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The map label for this gene is fur [H]

Identifier: 73539352

GI number: 73539352

Start: 2330659

End: 2331099

Strand: Reverse

Name: fur [H]

Synonym: Reut_B5530

Alternate gene names: 73539352

Gene position: 2331099-2330659 (Counterclockwise)

Preceding gene: 73539353

Following gene: 73539351

Centisome position: 85.51

GC content: 64.63

Gene sequence:

>441_bases
ATGCCAACTGTGATGTCCGATCCTGCCCACCTGAAGCGCGCTGGTCTCAAGGCGACGTCGCCGCGCATGCGCATCCTGGA
GGTGTTCCGCACCAGCGACCGGCGCCATCTGAGCGCCGAAGACGTTTATCGCATCCTGCTCACGCAGGACGACGACGCCG
GGCTGTCGACCGTGTACCGCGTGCTCAACCAGCTCGTGCAGGCCGAGATCCTGCTGCGCCACAGCTTCGAGTCGGATCAT
GCCGTGTTCGAGCTCAACGAGGGCGGCCATCACGACCATCTGATCTGCGTGAACTGCGGGCGCGTCGAGGAATTCCGGGA
CGAACGCATCGAGCAGCGCCAGCGCCAGGTGGCTGCCGACAACGATTTCGCGCTGCGTGAGCACATGCTGGTGCTGTATG
GCATCTGCCTGGAATGCCGGGCCGAACAACCGGCCGGCTGA

Upstream 100 bases:

>100_bases
ACGTCCGGGACGCACCGCAAGGGCGTTCCGGACGTCTTCCAGCCTGATTTCCAGCGATTTTCGCGACGCCATTTCTGGAT
GGCGCCTGTAGCCACATGCC

Downstream 100 bases:

>100_bases
CATGCACGGCGCGCCTTAGCAGGAGCCGATCATGGACCGACTGACCAAGCCTCTGTCCGAACTGAAGCGTTTGCTCAACC
TGTGCCTGCGCCAGGAGCCG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MPTVMSDPAHLKRAGLKATSPRMRILEVFRTSDRRHLSAEDVYRILLTQDDDAGLSTVYRVLNQLVQAEILLRHSFESDH
AVFELNEGGHHDHLICVNCGRVEEFRDERIEQRQRQVAADNDFALREHMLVLYGICLECRAEQPAG

Sequences:

>Translated_146_residues
MPTVMSDPAHLKRAGLKATSPRMRILEVFRTSDRRHLSAEDVYRILLTQDDDAGLSTVYRVLNQLVQAEILLRHSFESDH
AVFELNEGGHHDHLICVNCGRVEEFRDERIEQRQRQVAADNDFALREHMLVLYGICLECRAEQPAG
>Mature_145_residues
PTVMSDPAHLKRAGLKATSPRMRILEVFRTSDRRHLSAEDVYRILLTQDDDAGLSTVYRVLNQLVQAEILLRHSFESDHA
VFELNEGGHHDHLICVNCGRVEEFRDERIEQRQRQVAADNDFALREHMLVLYGICLECRAEQPAG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=137, Percent_Identity=52.5547445255474, Blast_Score=145, Evalue=1e-36,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16780; Mature: 16649

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTVMSDPAHLKRAGLKATSPRMRILEVFRTSDRRHLSAEDVYRILLTQDDDAGLSTVYR
CCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCHHHHHH
VLNQLVQAEILLRHSFESDHAVFELNEGGHHDHLICVNCGRVEEFRDERIEQRQRQVAAD
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
NDFALREHMLVLYGICLECRAEQPAG
CCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PTVMSDPAHLKRAGLKATSPRMRILEVFRTSDRRHLSAEDVYRILLTQDDDAGLSTVYR
CCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCHHHHHH
VLNQLVQAEILLRHSFESDHAVFELNEGGHHDHLICVNCGRVEEFRDERIEQRQRQVAAD
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
NDFALREHMLVLYGICLECRAEQPAG
CCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA