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The map label for this gene is gbpR [H]

Identifier: 73539333

GI number: 73539333

Start: 2307670

End: 2308707

Strand: Reverse

Name: gbpR [H]

Synonym: Reut_B5511

Alternate gene names: 73539333

Gene position: 2308707-2307670 (Counterclockwise)

Preceding gene: 73539338

Following gene: 73539326

Centisome position: 84.69

GC content: 68.21

Gene sequence:

>1038_bases
ATGGCATTCACCCCCACCGCTGACACGCTGGAATCCGCCAGCTTTCCACTGAGCCGCCTCAAGCTGCGGCACCTGCGCAT
CATCGTCGCGCTCGGCGAGATGCAGACCGCAGCGTCGGTGGCGGCGCGCATTCATGTGAGTCCGGCGGCCGTGTCGAAGA
CCCTCGCCGAAATCGAGGACATCGTCGGCATGCCGCTGTTCGTGCGCGGTCGCCGCGGGTTGGAGCTGACCGAAGCAGGG
CGCGAACTGGCGACGCACGGTCAGGTGTTGCTCACGCAGCTGGGCCGGCTCGCGGACTCCATGCAGGCGGTACGCGCCGG
GAACCAGGGCGAACTGCGGGTCGCGTTCCGGACCATGTCGGTGCAGCCATTCCTGGCGCAGGCGATGAGCGATTTCTACC
GCGACAACCCACGCGTCGAGATAAGCGTGATCGAAGGCGGTATTGGCGAACTGACCGAGCAGTTGCTGCAAGGCTCGCTG
GACCTGCTGTTCGCTTATGACGATCCACGGCTGTCGCGGCCCGCGCTGCGCAGCACGCCCGTAGTGCCGGCGCAGAAGGT
CGTGATCGTCGCCAGCCCGGACCACCCCTTGCTGGCGCGCCGCAAGTTCACGGCGCAGGCGTTGTCCGAACAGCAGTGGT
GCATTCCGGCTGCAGGTTCGCGCATGCTGCATCTGCTGCATACGGCCTTCCATGCGCTCGGTGCGCCGGCGCCATCGCAA
GGCATCCGCACGAGCGACGTCGCCGCGACCGCCAGCCTGATGCAGACCGGGCACTACCTGTCGGTGTTCCCGGAGCGCAT
TGCCGCGCAGCTCGCCTCGGCCAAGGTGGCGCGCGTGCTGCGCTTCGAACTCGACAGCCGTGTCGAACCGGTGGTCGCGG
TATGGAACGGCCAGATCACGCCACGTACCGCCGCACACCGCTTTCGCGATTTCGTGCTGCAGCGAGCCACGCAGGACGCC
TTGGGCGACGCGGAGCCACTGCTCGCGGCCCGCGCGGTGGCAGCGGCTGGCCTGGCACCGCGCCGCACCCACGGCTAA

Upstream 100 bases:

>100_bases
GCGGATGCGGCCGACTATAGGGGATCCTGTCCTGCACCAAAAGCGAATTAAAATCTCGTCATATTGAGCAAATGGTTAAC
TTACCGAACGGGCCCATGCC

Downstream 100 bases:

>100_bases
GCGGGCTGCCCGCCGCGAACGTCGCGACGATCAGAAGATATGCTTGATGCCCAGCATTGCGCCCGCCTGCGAAGCACCGG
GCGGCGGAGTTGCCGCGCCA

Product: regulatory protein LysR

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAFTPTADTLESASFPLSRLKLRHLRIIVALGEMQTAASVAARIHVSPAAVSKTLAEIEDIVGMPLFVRGRRGLELTEAG
RELATHGQVLLTQLGRLADSMQAVRAGNQGELRVAFRTMSVQPFLAQAMSDFYRDNPRVEISVIEGGIGELTEQLLQGSL
DLLFAYDDPRLSRPALRSTPVVPAQKVVIVASPDHPLLARRKFTAQALSEQQWCIPAAGSRMLHLLHTAFHALGAPAPSQ
GIRTSDVAATASLMQTGHYLSVFPERIAAQLASAKVARVLRFELDSRVEPVVAVWNGQITPRTAAHRFRDFVLQRATQDA
LGDAEPLLAARAVAAAGLAPRRTHG

Sequences:

>Translated_345_residues
MAFTPTADTLESASFPLSRLKLRHLRIIVALGEMQTAASVAARIHVSPAAVSKTLAEIEDIVGMPLFVRGRRGLELTEAG
RELATHGQVLLTQLGRLADSMQAVRAGNQGELRVAFRTMSVQPFLAQAMSDFYRDNPRVEISVIEGGIGELTEQLLQGSL
DLLFAYDDPRLSRPALRSTPVVPAQKVVIVASPDHPLLARRKFTAQALSEQQWCIPAAGSRMLHLLHTAFHALGAPAPSQ
GIRTSDVAATASLMQTGHYLSVFPERIAAQLASAKVARVLRFELDSRVEPVVAVWNGQITPRTAAHRFRDFVLQRATQDA
LGDAEPLLAARAVAAAGLAPRRTHG
>Mature_344_residues
AFTPTADTLESASFPLSRLKLRHLRIIVALGEMQTAASVAARIHVSPAAVSKTLAEIEDIVGMPLFVRGRRGLELTEAGR
ELATHGQVLLTQLGRLADSMQAVRAGNQGELRVAFRTMSVQPFLAQAMSDFYRDNPRVEISVIEGGIGELTEQLLQGSLD
LLFAYDDPRLSRPALRSTPVVPAQKVVIVASPDHPLLARRKFTAQALSEQQWCIPAAGSRMLHLLHTAFHALGAPAPSQG
IRTSDVAATASLMQTGHYLSVFPERIAAQLASAKVARVLRFELDSRVEPVVAVWNGQITPRTAAHRFRDFVLQRATQDAL
GDAEPLLAARAVAAAGLAPRRTHG

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790262, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=253, Percent_Identity=20.9486166007905, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=196, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=215, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081904, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=285, Percent_Identity=21.0526315789474, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.8219178082192, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37285; Mature: 37154

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTPTADTLESASFPLSRLKLRHLRIIVALGEMQTAASVAARIHVSPAAVSKTLAEIED
CCCCCCHHHHHHCCCCHHHHHHHHHHEEEECCCHHHHHHHHHHEECCHHHHHHHHHHHHH
IVGMPLFVRGRRGLELTEAGRELATHGQVLLTQLGRLADSMQAVRAGNQGELRVAFRTMS
HHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
VQPFLAQAMSDFYRDNPRVEISVIEGGIGELTEQLLQGSLDLLFAYDDPRLSRPALRSTP
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
VVPAQKVVIVASPDHPLLARRKFTAQALSEQQWCIPAAGSRMLHLLHTAFHALGAPAPSQ
CCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GIRTSDVAATASLMQTGHYLSVFPERIAAQLASAKVARVLRFELDSRVEPVVAVWNGQIT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PRTAAHRFRDFVLQRATQDALGDAEPLLAARAVAAAGLAPRRTHG
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AFTPTADTLESASFPLSRLKLRHLRIIVALGEMQTAASVAARIHVSPAAVSKTLAEIED
CCCCCHHHHHHCCCCHHHHHHHHHHEEEECCCHHHHHHHHHHEECCHHHHHHHHHHHHH
IVGMPLFVRGRRGLELTEAGRELATHGQVLLTQLGRLADSMQAVRAGNQGELRVAFRTMS
HHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
VQPFLAQAMSDFYRDNPRVEISVIEGGIGELTEQLLQGSLDLLFAYDDPRLSRPALRSTP
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
VVPAQKVVIVASPDHPLLARRKFTAQALSEQQWCIPAAGSRMLHLLHTAFHALGAPAPSQ
CCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GIRTSDVAATASLMQTGHYLSVFPERIAAQLASAKVARVLRFELDSRVEPVVAVWNGQIT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PRTAAHRFRDFVLQRATQDALGDAEPLLAARAVAAAGLAPRRTHG
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]