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The map label for this gene is zraR [H]

Identifier: 73539159

GI number: 73539159

Start: 2105624

End: 2107045

Strand: Reverse

Name: zraR [H]

Synonym: Reut_B5337

Alternate gene names: 73539159

Gene position: 2107045-2105624 (Counterclockwise)

Preceding gene: 73539160

Following gene: 73539157

Centisome position: 77.29

GC content: 65.33

Gene sequence:

>1422_bases
ATGCGCCGGGAAACCGGGATGAACAATAAGCCCAACGTCCGGGAGATCGTAATGGACCGACTGTGCAAGGCGCCGACACG
CGCCGCGCAGGTCGTGGTCGTGTCGCGTCATGAGGATTTTGGTTTTACCCCTGCCCAGTTCGGGCCGGGTTGGGACGTGC
GCCGCATCCAGCAGGTGCGCGACCTGGAGCGTATCGTGCGATCGAGCGCGCCCATGGCGGGCGTGATCGACCTGCAGACC
GAGTACAGCGATGTCGAGCTCGGGCAGCTGGAGCAGGGGCTGCAACACCTGCACGTGACGTGGGTGGCCATCACCACCGA
TGCACGTCTTGCGGACCAGCGCATACGCCGGCTGATCCGCGACTATTGCGTCGACTATGTGCGCACGCCGTTCTCGCATG
ACGAACTGCTCTACACGCTCAAGCATGCGCATGGCATGGCGTGCCTGCATCACGGGCGCACCACCGAGATGGCGCCGCAT
GGGACCATGATCGGCGAATGCGCGTCGATGCGTGCGATGTTCCGCTCGCTCGCCAAGGTGGCGCACAACGAGGCGCCGGT
GTTCATCTCGGGCGAGTCGGGCACGGGCAAGGAGCTCGCAGCACAGGCCATCCATGAGGCATCGAGCCGGCGCAAGGGAC
CTTTCGTTGCGATCAACTGCGGCGCGATTCCTTCACACCTCGTGCAGTCGGAGCTGTTCGGCTACGAGAAGGGCGCGTTC
ACCGGCGCGAACCAGCGCAAGATCGGTTGGATCGAGCAGGCGCAGGGCGGCACGCTGTTCCTCGATGAAATCGGCGACCT
GCCGCTCGAAAGTCAGGTGGCGCTGTTGCGCTTCCTGCAGCAGGGCACCATCACCAGGCTGGGCGGACACCAGTCCATTC
CGCTGGATCTGCGCATCATCTCGGCCACGCACGTGGACCTGGTGGCGGCGCAGGCCGATGGCCGCTTCCGCGCGGACTTG
TTCCACCGGCTCTGCGTGCTCACGCTGACCATCCCCGCATTGCGCGAACGCGGCGAGGACATCCTGCTGCTTGCCAATGC
GGTACTGGCCGAGCACGGGCACGAAGCCCACCGGCGCATCCGCGGATTCTCGCCATGCGCCACGCAGGCGATGATGCAAT
ACGCCTGGCCGGGCAATGTGCGGGAGCTGATCAACCGCGTGCGGCGTGCGATCGTGATGACCGACAACCGCAAGATTACC
GCAGAGGACCTGCAATTGCATGGTGGCGCCGAGTTGCCGCGCAAGACGCTCGATGCGATTCGCGAGGAGGCCGAACGCGA
GGCGATCCGCAGTGTCATGGCGAGCCACGGCTTCCATGTCGTGCCCGCCGCGCGCGAACTCAACGTGTCGCGCGTGACGC
TGTACCGGCTCATGCACAAGCACAACATCCGCGTGGAGACGCAGCAGACGGCCGGCGAGTAA

Upstream 100 bases:

>100_bases
GCGATCCGCTTGCTGTCATGGATGAACCAGCACGCAGTCAGTCCAGTTCGTGACACCGACGTCAAACCCGCGGCGGCAAC
GGCCGGGAGGGCCGGAACCG

Downstream 100 bases:

>100_bases
GCCGGCGAACGGTTGAGCCGACTGGCCGCATGCGCGCGCCAGGCGCTCCAGGGAAAGGGGAACTGGCGACGTCCGCTCGC
CGGTTCCCCCTTCCCCGTGC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MRRETGMNNKPNVREIVMDRLCKAPTRAAQVVVVSRHEDFGFTPAQFGPGWDVRRIQQVRDLERIVRSSAPMAGVIDLQT
EYSDVELGQLEQGLQHLHVTWVAITTDARLADQRIRRLIRDYCVDYVRTPFSHDELLYTLKHAHGMACLHHGRTTEMAPH
GTMIGECASMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHEASSRRKGPFVAINCGAIPSHLVQSELFGYEKGAF
TGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLDLRIISATHVDLVAAQADGRFRADL
FHRLCVLTLTIPALRERGEDILLLANAVLAEHGHEAHRRIRGFSPCATQAMMQYAWPGNVRELINRVRRAIVMTDNRKIT
AEDLQLHGGAELPRKTLDAIREEAEREAIRSVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVETQQTAGE

Sequences:

>Translated_473_residues
MRRETGMNNKPNVREIVMDRLCKAPTRAAQVVVVSRHEDFGFTPAQFGPGWDVRRIQQVRDLERIVRSSAPMAGVIDLQT
EYSDVELGQLEQGLQHLHVTWVAITTDARLADQRIRRLIRDYCVDYVRTPFSHDELLYTLKHAHGMACLHHGRTTEMAPH
GTMIGECASMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHEASSRRKGPFVAINCGAIPSHLVQSELFGYEKGAF
TGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLDLRIISATHVDLVAAQADGRFRADL
FHRLCVLTLTIPALRERGEDILLLANAVLAEHGHEAHRRIRGFSPCATQAMMQYAWPGNVRELINRVRRAIVMTDNRKIT
AEDLQLHGGAELPRKTLDAIREEAEREAIRSVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVETQQTAGE
>Mature_473_residues
MRRETGMNNKPNVREIVMDRLCKAPTRAAQVVVVSRHEDFGFTPAQFGPGWDVRRIQQVRDLERIVRSSAPMAGVIDLQT
EYSDVELGQLEQGLQHLHVTWVAITTDARLADQRIRRLIRDYCVDYVRTPFSHDELLYTLKHAHGMACLHHGRTTEMAPH
GTMIGECASMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHEASSRRKGPFVAINCGAIPSHLVQSELFGYEKGAF
TGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLDLRIISATHVDLVAAQADGRFRADL
FHRLCVLTLTIPALRERGEDILLLANAVLAEHGHEAHRRIRGFSPCATQAMMQYAWPGNVRELINRVRRAIVMTDNRKIT
AEDLQLHGGAELPRKTLDAIREEAEREAIRSVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVETQQTAGE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=287, Percent_Identity=47.0383275261324, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1790437, Length=343, Percent_Identity=41.1078717201166, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1788905, Length=285, Percent_Identity=44.9122807017544, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1790299, Length=284, Percent_Identity=44.3661971830986, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=41.6149068322981, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=40.7407407407407, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.2597402597403, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1786524, Length=358, Percent_Identity=39.1061452513966, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI87082152, Length=329, Percent_Identity=39.8176291793313, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=36.25, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=300, Percent_Identity=34.3333333333333, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=33.2191780821918, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=35.2941176470588, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52904; Mature: 52904

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRETGMNNKPNVREIVMDRLCKAPTRAAQVVVVSRHEDFGFTPAQFGPGWDVRRIQQVR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
DLERIVRSSAPMAGVIDLQTEYSDVELGQLEQGLQHLHVTWVAITTDARLADQRIRRLIR
HHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHH
DYCVDYVRTPFSHDELLYTLKHAHGMACLHHGRTTEMAPHGTMIGECASMRAMFRSLAKV
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHNEAPVFISGESGTGKELAAQAIHEASSRRKGPFVAINCGAIPSHLVQSELFGYEKGAF
HCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
TGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLDLRII
CCCCCCCCCCCEECCCCEEEHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEE
SATHVDLVAAQADGRFRADLFHRLCVLTLTIPALRERGEDILLLANAVLAEHGHEAHRRI
EECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHH
RGFSPCATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAI
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCEEEHHHHEECCCCCCCHHHHHHH
REEAEREAIRSVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVETQQTAGE
HHHHHHHHHHHHHHHCCCEEECCHHHCCHHHHHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MRRETGMNNKPNVREIVMDRLCKAPTRAAQVVVVSRHEDFGFTPAQFGPGWDVRRIQQVR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
DLERIVRSSAPMAGVIDLQTEYSDVELGQLEQGLQHLHVTWVAITTDARLADQRIRRLIR
HHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHH
DYCVDYVRTPFSHDELLYTLKHAHGMACLHHGRTTEMAPHGTMIGECASMRAMFRSLAKV
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHNEAPVFISGESGTGKELAAQAIHEASSRRKGPFVAINCGAIPSHLVQSELFGYEKGAF
HCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
TGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLDLRII
CCCCCCCCCCCEECCCCEEEHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEE
SATHVDLVAAQADGRFRADLFHRLCVLTLTIPALRERGEDILLLANAVLAEHGHEAHRRI
EECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHH
RGFSPCATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAI
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCEEEHHHHEECCCCCCCHHHHHHH
REEAEREAIRSVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVETQQTAGE
HHHHHHHHHHHHHHHCCCEEECCHHHCCHHHHHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]