The gene/protein map for NC_007348 is currently unavailable.
Definition Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession NC_007348
Length 2,726,152

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The map label for this gene is kduD [H]

Identifier: 73539112

GI number: 73539112

Start: 2051230

End: 2052021

Strand: Reverse

Name: kduD [H]

Synonym: Reut_B5289

Alternate gene names: 73539112

Gene position: 2052021-2051230 (Counterclockwise)

Preceding gene: 73539113

Following gene: 73539111

Centisome position: 75.27

GC content: 66.67

Gene sequence:

>792_bases
ATGAACCATGAGGACGGACGCAGCCTGAACCCGTTCGCTGATCTGGAGGGCAAGGTGGCGCTGGTCACCGGCGCCTTCGG
TGGACTGGGTCTGCATTTCGCGAAGACCCTGTCGCGCGCCGGCTGCAAGGTGGCATTGGCCGGACGGCGTGTGGGCGAAG
GCGAGGCGCTGCTGGCCGAACTGCGCAAGCAGGGTGGACAGGGTTGCGTGGTCGCGCTCGACGTCAGGGACCCCACCTGG
GTCGATTCGGCATTCGAGCGAGCGCAGCAAGAGCTGGGTCCGGTGCAGATCGTCGTCAACAGCGCCGGCATTGCAACCAC
CGGCGCGGCCATGGACGTGGACGAGGCGCAGTGGCAAAGCGTGATCGACACCAACCTGAACGGCGCCTGGCGCGTGGCGC
AGCGTGCCGCGCGCATGATGCGCGACACCGACACGCACGGCAGCATCATCAACATCGCGTCGATCCTCGGGCTACGCGTG
GCCCAGCAGGTGCCGGCATACACCGCAGCCAAAGCGGGCCTGATCCACCTGACGCGCTCGCTCGCGCTGGAGTGGGCGCG
CCATGGCATCCGCGTCAATGCGTTGGCGCCGGGTTACTTCGAGACCGAGATCAACCGCAGCTTTTTCGAGACCGAGAGCG
GGCAGGCGCTGATCCGGCGCATCCCGCAGCGCAGGCTCGGTCAGCCGCGGCAGCTCGACGGCGCGCTGCTGTTACTGGCG
TCTGACGCATCCGATTTCATGACCGGCACGGTGCTGCCTGTCGACGGTGGCCATTCCATCAATTCGCTTTAA

Upstream 100 bases:

>100_bases
CAAGACCATGATGGTGTTCGGCGACGCCAAGAAGGTGGTCGAGGACATGGTCAAGGCGGCGTAAGCACTACGTCATACGG
ATATCGGAGGAGACATGGCA

Downstream 100 bases:

>100_bases
GGCAAGCCTCCATGTTCACTCCCTGCCCCACCGAACGCAGCAAGGCCATTGCCGACCGCGTCGAGGCATTCGTGCGCGAC
GTTGTCGCGCCGTATGAGCG

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNHEDGRSLNPFADLEGKVALVTGAFGGLGLHFAKTLSRAGCKVALAGRRVGEGEALLAELRKQGGQGCVVALDVRDPTW
VDSAFERAQQELGPVQIVVNSAGIATTGAAMDVDEAQWQSVIDTNLNGAWRVAQRAARMMRDTDTHGSIINIASILGLRV
AQQVPAYTAAKAGLIHLTRSLALEWARHGIRVNALAPGYFETEINRSFFETESGQALIRRIPQRRLGQPRQLDGALLLLA
SDASDFMTGTVLPVDGGHSINSL

Sequences:

>Translated_263_residues
MNHEDGRSLNPFADLEGKVALVTGAFGGLGLHFAKTLSRAGCKVALAGRRVGEGEALLAELRKQGGQGCVVALDVRDPTW
VDSAFERAQQELGPVQIVVNSAGIATTGAAMDVDEAQWQSVIDTNLNGAWRVAQRAARMMRDTDTHGSIINIASILGLRV
AQQVPAYTAAKAGLIHLTRSLALEWARHGIRVNALAPGYFETEINRSFFETESGQALIRRIPQRRLGQPRQLDGALLLLA
SDASDFMTGTVLPVDGGHSINSL
>Mature_263_residues
MNHEDGRSLNPFADLEGKVALVTGAFGGLGLHFAKTLSRAGCKVALAGRRVGEGEALLAELRKQGGQGCVVALDVRDPTW
VDSAFERAQQELGPVQIVVNSAGIATTGAAMDVDEAQWQSVIDTNLNGAWRVAQRAARMMRDTDTHGSIINIASILGLRV
AQQVPAYTAAKAGLIHLTRSLALEWARHGIRVNALAPGYFETEINRSFFETESGQALIRRIPQRRLGQPRQLDGALLLLA
SDASDFMTGTVLPVDGGHSINSL

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=31.1111111111111, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=33.75, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=33.4677419354839, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=32.2709163346614, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=30.7377049180328, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.1632653061224, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4503301, Length=261, Percent_Identity=27.9693486590038, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=32.421875, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI31542939, Length=253, Percent_Identity=29.6442687747036, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=26.2295081967213, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=26.9430051813472, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=31.1557788944724, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=29.9145299145299, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=27.3809523809524, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=30.859375, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI209862901, Length=208, Percent_Identity=29.8076923076923, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI19923983, Length=208, Percent_Identity=29.8076923076923, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=31.9767441860465, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=28.643216080402, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=37.2950819672131, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=34, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.1428571428571, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.078431372549, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=34.0996168582375, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=32.3651452282158, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.0411522633745, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=29.0836653386454, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=28.2352941176471, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=201, Percent_Identity=29.3532338308458, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=34.0080971659919, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=29.3172690763052, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561272, Length=253, Percent_Identity=33.9920948616601, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=30, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.4, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=27.2, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.188679245283, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=28.8537549407115, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=28.3018867924528, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=30.5970149253731, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=25.9398496240602, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=25.0950570342205, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.1954887218045, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=31.2252964426877, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.4367816091954, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=27.7566539923954, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=25.3787878787879, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=25.9541984732824, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=27.3764258555133, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=27.8810408921933, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=26.1992619926199, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=27.6752767527675, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=25.4681647940075, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=228, Percent_Identity=30.2631578947368, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=219, Percent_Identity=29.6803652968037, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=26.2773722627737, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86565303, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=23.5897435897436, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=28.6290322580645, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=205, Percent_Identity=31.219512195122, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=186, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=32.2448979591837, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.8709677419355, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=32.4, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=33.4677419354839, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=31.25, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=29.4820717131474, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.7619047619048, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=33.6683417085427, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.1338582677165, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=28.4615384615385, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=34.0314136125654, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584752, Length=191, Percent_Identity=30.3664921465969, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=31, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=31, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=29.5918367346939, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571387, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=31.6582914572864, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007234, Length=202, Percent_Identity=30.6930693069307, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007238, Length=220, Percent_Identity=29.0909090909091, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24663911, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24665264, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364494, Length=203, Percent_Identity=30.5418719211823, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 28116; Mature: 28116

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNHEDGRSLNPFADLEGKVALVTGAFGGLGLHFAKTLSRAGCKVALAGRRVGEGEALLAE
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
LRKQGGQGCVVALDVRDPTWVDSAFERAQQELGPVQIVVNSAGIATTGAAMDVDEAQWQS
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCCHHHHHHH
VIDTNLNGAWRVAQRAARMMRDTDTHGSIINIASILGLRVAQQVPAYTAAKAGLIHLTRS
HHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LALEWARHGIRVNALAPGYFETEINRSFFETESGQALIRRIPQRRLGQPRQLDGALLLLA
HHHHHHHCCEEEEEECCCHHHHHHCHHHHHCCCCHHHHHHCCHHHCCCCCCCCCEEEEEE
SDASDFMTGTVLPVDGGHSINSL
CCCCHHHCCEEEECCCCCCCCCC
>Mature Secondary Structure
MNHEDGRSLNPFADLEGKVALVTGAFGGLGLHFAKTLSRAGCKVALAGRRVGEGEALLAE
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
LRKQGGQGCVVALDVRDPTWVDSAFERAQQELGPVQIVVNSAGIATTGAAMDVDEAQWQS
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCCHHHHHHH
VIDTNLNGAWRVAQRAARMMRDTDTHGSIINIASILGLRVAQQVPAYTAAKAGLIHLTRS
HHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LALEWARHGIRVNALAPGYFETEINRSFFETESGQALIRRIPQRRLGQPRQLDGALLLLA
HHHHHHHCCEEEEEECCCHHHHHHCHHHHHCCCCHHHHHHCCHHHCCCCCCCCCEEEEEE
SDASDFMTGTVLPVDGGHSINSL
CCCCHHHCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766386 [H]