Click here to switch to the map view.

The map label for this gene is pntB [H]

Identifier: 73539113

GI number: 73539113

Start: 2052058

End: 2053524

Strand: Reverse

Name: pntB [H]

Synonym: Reut_B5290

Alternate gene names: 73539113

Gene position: 2053524-2052058 (Counterclockwise)

Preceding gene: 73539114

Following gene: 73539112

Centisome position: 75.33

GC content: 63.53

Gene sequence:

>1467_bases
ATGAACGGACTGTCCATGAATACCGTGACGCTGTTCTACCTGGGCGCGTCAGTCTGCTTTATCCAGGCCCTCAAAGGGCT
TTCGCACCCGGCTTCGGCCCGCAAGGGCAATGCCTTCGGCATGATCGGCATGGCGGTGGCGGCACTCACCACGGTGGCGC
TGATCCTCAAGCTCAAGAACGAGTTCCTCGCTGCCGGTAGCGGCACGACAGCCGGGTCTGGCCTTGCGCTGATCCTGGCT
GGCCTGGTCGTCGGCGGCGGCATCGGCGCCTACGTGGCAAAGAAGGTCGAGATGACCAAGATGCCCGAACTGGTCGCGGC
GATGCACTCGCTGATCGGTCTCGCGGCGGTGTGCATTGCGGTGGCCGCGGTGGCGGAACCTTCCGCCTTTGGTATTGCGC
CGGCGGGCTCGCATGAGATTCCGATGGGCAACCGCATCGAACTGTTCATCGGCTGCTTCGTCGGTGCCATCACGTTCTCC
GGTTCCGTGATCGCCTTCGGCAAGCTGGCAGGTCGCTACAAGTTCCGCCTGTTCCAGGGTGCCCCCGTTGTGTTCGCGGG
CCAGCACATGCTGAACCTGGCGCTGGCCGTCGCCATGGTCGGCTTCGGCATTGCGTTCTTCATGACGCAGGAGTGGACGC
CGTTCCTCGTCATGCTGGCCATCGCCTTCGTGCTCGGCGTGCTGATCATCATCCCGATCGGCGGCGCCGACATGCCGGTG
GTGGTGTCGATGCTGAACTCGTACTCGGGCTGGGCGGCCGCCGGTATCGGCTTCTCGCTGAACAACCCGATGCTGATCAT
TGCCGGTTCGCTGGTGGGTTCGTCCGGTGCCATCCTCTCGTACATCATGTGCAAGGCGATGAACCGTTCGTTCTTCAACG
TGATCCTCGGCGGCTTCGGCAGCGATGCGGGAGCGAGCGCAGCAGGCGGTTCGCAAGTGCAGCGCAACGTAAAGTCGGGC
TCCGCCGATGACGCCTCGTTCCTGATGGGCAATGCCGAGACCGTGATCATCGTGCCGGGTTACGGCCTGGCAGTGGCGCG
CGCCCAGCACGCACTCAAGGAACTGACCGAAAAGCTGACCGAGAAGGGCGTGACCGTGAAGTACGCGATCCACCCGGTGG
CGGGCCGCATGCCGGGCCACATGAACGTGCTGCTGGCCGAGGCCGAGGTGCCCTACGACCAGGTCTTCGAGATGGAAGAC
ATCAACAGCGAGTTCGGCCAGGCCGACGTGGTGCTGGTGCTCGGCGCGAACGACGTGGTGAACCCGTCGGCCAAGACCGA
TCCGAAATCACCGATCGCCGGCATGCCGATCCTGGAGGCGTACAAGGCCAAGACCATCATCGTGAACAAGCGTTCGATGG
CGGCCGGCTACGCCGGCCTCGACAACGAGCTGTTCTACATGGACAAGACCATGATGGTGTTCGGCGACGCCAAGAAGGTG
GTCGAGGACATGGTCAAGGCGGCGTAA

Upstream 100 bases:

>100_bases
TGCTAGAGATGTTCCGCAAGAAGGCGCCGAAGGTGAAGGCCGAGGCGCAGCCCGCAAAGACGCCCGCGCACGCCGGCGGA
GAACTGGTGGAGATGCCGCG

Downstream 100 bases:

>100_bases
GCACTACGTCATACGGATATCGGAGGAGACATGGCAATGAACCATGAGGACGGACGCAGCCTGAACCCGTTCGCTGATCT
GGAGGGCAAGGTGGCGCTGG

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNGLSMNTVTLFYLGASVCFIQALKGLSHPASARKGNAFGMIGMAVAALTTVALILKLKNEFLAAGSGTTAGSGLALILA
GLVVGGGIGAYVAKKVEMTKMPELVAAMHSLIGLAAVCIAVAAVAEPSAFGIAPAGSHEIPMGNRIELFIGCFVGAITFS
GSVIAFGKLAGRYKFRLFQGAPVVFAGQHMLNLALAVAMVGFGIAFFMTQEWTPFLVMLAIAFVLGVLIIIPIGGADMPV
VVSMLNSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGSDAGASAAGGSQVQRNVKSG
SADDASFLMGNAETVIIVPGYGLAVARAQHALKELTEKLTEKGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMED
INSEFGQADVVLVLGANDVVNPSAKTDPKSPIAGMPILEAYKAKTIIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKV
VEDMVKAA

Sequences:

>Translated_488_residues
MNGLSMNTVTLFYLGASVCFIQALKGLSHPASARKGNAFGMIGMAVAALTTVALILKLKNEFLAAGSGTTAGSGLALILA
GLVVGGGIGAYVAKKVEMTKMPELVAAMHSLIGLAAVCIAVAAVAEPSAFGIAPAGSHEIPMGNRIELFIGCFVGAITFS
GSVIAFGKLAGRYKFRLFQGAPVVFAGQHMLNLALAVAMVGFGIAFFMTQEWTPFLVMLAIAFVLGVLIIIPIGGADMPV
VVSMLNSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGSDAGASAAGGSQVQRNVKSG
SADDASFLMGNAETVIIVPGYGLAVARAQHALKELTEKLTEKGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMED
INSEFGQADVVLVLGANDVVNPSAKTDPKSPIAGMPILEAYKAKTIIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKV
VEDMVKAA
>Mature_488_residues
MNGLSMNTVTLFYLGASVCFIQALKGLSHPASARKGNAFGMIGMAVAALTTVALILKLKNEFLAAGSGTTAGSGLALILA
GLVVGGGIGAYVAKKVEMTKMPELVAAMHSLIGLAAVCIAVAAVAEPSAFGIAPAGSHEIPMGNRIELFIGCFVGAITFS
GSVIAFGKLAGRYKFRLFQGAPVVFAGQHMLNLALAVAMVGFGIAFFMTQEWTPFLVMLAIAFVLGVLIIIPIGGADMPV
VVSMLNSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGSDAGASAAGGSQVQRNVKSG
SADDASFLMGNAETVIIVPGYGLAVARAQHALKELTEKLTEKGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMED
INSEFGQADVVLVLGANDVVNPSAKTDPKSPIAGMPILEAYKAKTIIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKV
VEDMVKAA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=484, Percent_Identity=47.3140495867769, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI122939153, Length=484, Percent_Identity=47.3140495867769, Blast_Score=404, Evalue=1e-112,
Organism=Escherichia coli, GI1787886, Length=483, Percent_Identity=50.7246376811594, Blast_Score=453, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17550456, Length=479, Percent_Identity=41.9624217118998, Blast_Score=359, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50557; Mature: 50557

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLSMNTVTLFYLGASVCFIQALKGLSHPASARKGNAFGMIGMAVAALTTVALILKLKN
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EFLAAGSGTTAGSGLALILAGLVVGGGIGAYVAKKVEMTKMPELVAAMHSLIGLAAVCIA
HHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAVAEPSAFGIAPAGSHEIPMGNRIELFIGCFVGAITFSGSVIAFGKLAGRYKFRLFQG
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCEEEEEEECC
APVVFAGQHMLNLALAVAMVGFGIAFFMTQEWTPFLVMLAIAFVLGVLIIIPIGGADMPV
CCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCHHH
VVSMLNSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFG
HHHHHHCCCCCEEECCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHCCC
SDAGASAAGGSQVQRNVKSGSADDASFLMGNAETVIIVPGYGLAVARAQHALKELTEKLT
CCCCCCCCCCHHHHHHHHCCCCCCCHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EKGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINSEFGQADVVLVLGANDVV
HCCCEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
NPSAKTDPKSPIAGMPILEAYKAKTIIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKV
CCCCCCCCCCCCCCCCHHHHHCCEEEEEECCHHHCCCCCCCCCEEEECCEEEEECCHHHH
VEDMVKAA
HHHHHHCC
>Mature Secondary Structure
MNGLSMNTVTLFYLGASVCFIQALKGLSHPASARKGNAFGMIGMAVAALTTVALILKLKN
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EFLAAGSGTTAGSGLALILAGLVVGGGIGAYVAKKVEMTKMPELVAAMHSLIGLAAVCIA
HHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAVAEPSAFGIAPAGSHEIPMGNRIELFIGCFVGAITFSGSVIAFGKLAGRYKFRLFQG
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCEEEEEEECC
APVVFAGQHMLNLALAVAMVGFGIAFFMTQEWTPFLVMLAIAFVLGVLIIIPIGGADMPV
CCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCHHH
VVSMLNSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFG
HHHHHHCCCCCEEECCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHCCC
SDAGASAAGGSQVQRNVKSGSADDASFLMGNAETVIIVPGYGLAVARAQHALKELTEKLT
CCCCCCCCCCHHHHHHHHCCCCCCCHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EKGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINSEFGQADVVLVLGANDVV
HCCCEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
NPSAKTDPKSPIAGMPILEAYKAKTIIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKV
CCCCCCCCCCCCCCCCHHHHHCCEEEEEECCHHHCCCCCCCCCEEEECCEEEEECCHHHH
VEDMVKAA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]