Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 73538966

GI number: 73538966

Start: 1881062

End: 1882366

Strand: Direct

Name: ttuB [H]

Synonym: Reut_B5141

Alternate gene names: 73538966

Gene position: 1881062-1882366 (Clockwise)

Preceding gene: 73538965

Following gene: 73538967

Centisome position: 69.0

GC content: 61.23

Gene sequence:

>1305_bases
GTGGAAACTACCCTGCACGCCGGGGCAAAGGTGAGTTCGTACGAAGACGCGGTTTATCGCAAGGTAAGCTGGCGCCTCGT
GCCGTTCCTGATGCTTTGCTTCCTGATTGCCTATCTCGACCGAGTCAACGTCGGCTTTGCCAAGCTCCAGATGTCGCAGG
ACCTTGGCTTCAGCGAAACCGTCTATGGCCTGGGCGCCGGCATCTTCTTCATCGGATACTTCCTGTTCGAGATACCCAGC
AACCTTGCGCTTCACCGCTTCGGCGCCAAGGTCTGGATCGGCCGGATCATGGTGACATGGGGCCTGCTTTCGGCGTGCTT
CGTGTTCGTGGAGACCCCGACTGCTTTCTACACCTTGCGTTTCCTGCTGGGCCTGGCCGAAGCGGGCTTCACGCCCGGCA
TCGTGTACTACTTGTCCTGCTGGTATCCCTCGCATCGGCGCGCCAAGATCATGGCGATCTATTGCATGGGCTCGCCGCTG
TCCGGCATCATCGGCAACCCGTTGTCAGGCTTTTTGATGGGCAGCATGGGGGGCATTGCGGGTTGGGCGGGCTGGCAATG
GATGTTCTTCATTGAAGCCGTGCCTGCCATATTGCTGGGCCTCGCCTGCTTCTTCTACCTGGACAGTTCCATCTCCAAGG
CCAAATGGCTCAGTGACGACGAGAAGCGCGTGCTCGAGCTGGCCAAGGCGGAGGACAACAAGGCGGCGGGCCATGAGGCG
CGCGTGGGCAACGTCTTCACCGACCCGCGTGTCTGGCTCATCAGCCTGATCTGCTTCTGCTATGTCACCGGGCAGTACGG
CATTACGCTCTGGCTGCCAACGTTCATCAAGTCGACAGGTGTGTCCGATCCGCTGCATATCGGCCTGCTCAGCGCGATCC
CGTATATGGCGGCCATCGTCACCATGTACGTGTTCGGCAAGAGCGCGGATAAGCATCGGGAACGGCGCTGGCACCTGATC
GTGCCCTGCATGATGGGCGCCATCGGCTTCCTGGCCCTGCCCTGGATCATGCACAGCACGGCGCTCTCGCTGGTGTTCCT
GTCGATTGCCGCGGCCGGCATCCTGACCTGTTCGCCGCTGTTCTGGTCCCTGCCTACCGCCTTCCTCAGCGGCGCGGCGG
CGGCGACGGCCATCGCCATGAGCAATTCGATCGGCAACCTGGCCGGCTTTACCAGCGGCTACATGATCGGGTATCTGCGT
GACGTAACCCAGAGCGGTACCAGCGCGTACTACATGATTGCGGGCATGCTTGTCCTTGGCGCGTTCGCCATCTGGACCTT
GCCGGCAAAGCTGGTCAACCGGTAG

Upstream 100 bases:

>100_bases
CCCCGGCGGTACAGGCCCATTCCACGTTCCACACAGCGCCGATCGGCTCCAGCATCGGCGCAGCAGCACCGACGTACCTG
ACAATACAAAAGGAGACGCT

Downstream 100 bases:

>100_bases
CGCATGTCGGGGAGCGGCGTGCCGCTCCCCGACGACTCATCACCCCGGCGCCCTTCCCGTGGGCGCAAGGAACACAAACA
TGAAATCAACCACCGACTCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
METTLHAGAKVSSYEDAVYRKVSWRLVPFLMLCFLIAYLDRVNVGFAKLQMSQDLGFSETVYGLGAGIFFIGYFLFEIPS
NLALHRFGAKVWIGRIMVTWGLLSACFVFVETPTAFYTLRFLLGLAEAGFTPGIVYYLSCWYPSHRRAKIMAIYCMGSPL
SGIIGNPLSGFLMGSMGGIAGWAGWQWMFFIEAVPAILLGLACFFYLDSSISKAKWLSDDEKRVLELAKAEDNKAAGHEA
RVGNVFTDPRVWLISLICFCYVTGQYGITLWLPTFIKSTGVSDPLHIGLLSAIPYMAAIVTMYVFGKSADKHRERRWHLI
VPCMMGAIGFLALPWIMHSTALSLVFLSIAAAGILTCSPLFWSLPTAFLSGAAAATAIAMSNSIGNLAGFTSGYMIGYLR
DVTQSGTSAYYMIAGMLVLGAFAIWTLPAKLVNR

Sequences:

>Translated_434_residues
METTLHAGAKVSSYEDAVYRKVSWRLVPFLMLCFLIAYLDRVNVGFAKLQMSQDLGFSETVYGLGAGIFFIGYFLFEIPS
NLALHRFGAKVWIGRIMVTWGLLSACFVFVETPTAFYTLRFLLGLAEAGFTPGIVYYLSCWYPSHRRAKIMAIYCMGSPL
SGIIGNPLSGFLMGSMGGIAGWAGWQWMFFIEAVPAILLGLACFFYLDSSISKAKWLSDDEKRVLELAKAEDNKAAGHEA
RVGNVFTDPRVWLISLICFCYVTGQYGITLWLPTFIKSTGVSDPLHIGLLSAIPYMAAIVTMYVFGKSADKHRERRWHLI
VPCMMGAIGFLALPWIMHSTALSLVFLSIAAAGILTCSPLFWSLPTAFLSGAAAATAIAMSNSIGNLAGFTSGYMIGYLR
DVTQSGTSAYYMIAGMLVLGAFAIWTLPAKLVNR
>Mature_434_residues
METTLHAGAKVSSYEDAVYRKVSWRLVPFLMLCFLIAYLDRVNVGFAKLQMSQDLGFSETVYGLGAGIFFIGYFLFEIPS
NLALHRFGAKVWIGRIMVTWGLLSACFVFVETPTAFYTLRFLLGLAEAGFTPGIVYYLSCWYPSHRRAKIMAIYCMGSPL
SGIIGNPLSGFLMGSMGGIAGWAGWQWMFFIEAVPAILLGLACFFYLDSSISKAKWLSDDEKRVLELAKAEDNKAAGHEA
RVGNVFTDPRVWLISLICFCYVTGQYGITLWLPTFIKSTGVSDPLHIGLLSAIPYMAAIVTMYVFGKSADKHRERRWHLI
VPCMMGAIGFLALPWIMHSTALSLVFLSIAAAGILTCSPLFWSLPTAFLSGAAAATAIAMSNSIGNLAGFTSGYMIGYLR
DVTQSGTSAYYMIAGMLVLGAFAIWTLPAKLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=391, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=36.2559241706161, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI2367379, Length=293, Percent_Identity=23.5494880546075, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=22.6244343891403, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082320, Length=400, Percent_Identity=22.5, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789515, Length=427, Percent_Identity=22.9508196721311, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=236, Percent_Identity=25.8474576271186, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319250, Length=313, Percent_Identity=23.6421725239617, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321698, Length=327, Percent_Identity=24.1590214067278, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321502, Length=378, Percent_Identity=24.8677248677249, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=149, Percent_Identity=28.1879194630872, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=257, Percent_Identity=26.0700389105058, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=335, Percent_Identity=23.5820895522388, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=279, Percent_Identity=22.9390681003584, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20130135, Length=343, Percent_Identity=23.6151603498542, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=23.3516483516484, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24653727, Length=386, Percent_Identity=21.5025906735751, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655271, Length=313, Percent_Identity=22.3642172523962, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639764, Length=441, Percent_Identity=22.9024943310658, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550460, Length=308, Percent_Identity=23.7012987012987, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47626; Mature: 47626

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTLHAGAKVSSYEDAVYRKVSWRLVPFLMLCFLIAYLDRVNVGFAKLQMSQDLGFSET
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHCCCCHHH
VYGLGAGIFFIGYFLFEIPSNLALHRFGAKVWIGRIMVTWGLLSACFVFVETPTAFYTLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLLGLAEAGFTPGIVYYLSCWYPSHRRAKIMAIYCMGSPLSGIIGNPLSGFLMGSMGGIA
HHHHHHHCCCCCCHHHHEEECCCCCCCEEEEEEEEECCCCCHHHCCCHHHHHHHCCCCCC
GWAGWQWMFFIEAVPAILLGLACFFYLDSSISKAKWLSDDEKRVLELAKAEDNKAAGHEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCC
RVGNVFTDPRVWLISLICFCYVTGQYGITLWLPTFIKSTGVSDPLHIGLLSAIPYMAAIV
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TMYVFGKSADKHRERRWHLIVPCMMGAIGFLALPWIMHSTALSLVFLSIAAAGILTCSPL
HHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWSLPTAFLSGAAAATAIAMSNSIGNLAGFTSGYMIGYLRDVTQSGTSAYYMIAGMLVLG
HHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AFAIWTLPAKLVNR
HHHHHHHHHHHHCC
>Mature Secondary Structure
METTLHAGAKVSSYEDAVYRKVSWRLVPFLMLCFLIAYLDRVNVGFAKLQMSQDLGFSET
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHCCCCHHH
VYGLGAGIFFIGYFLFEIPSNLALHRFGAKVWIGRIMVTWGLLSACFVFVETPTAFYTLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLLGLAEAGFTPGIVYYLSCWYPSHRRAKIMAIYCMGSPLSGIIGNPLSGFLMGSMGGIA
HHHHHHHCCCCCCHHHHEEECCCCCCCEEEEEEEEECCCCCHHHCCCHHHHHHHCCCCCC
GWAGWQWMFFIEAVPAILLGLACFFYLDSSISKAKWLSDDEKRVLELAKAEDNKAAGHEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCC
RVGNVFTDPRVWLISLICFCYVTGQYGITLWLPTFIKSTGVSDPLHIGLLSAIPYMAAIV
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TMYVFGKSADKHRERRWHLIVPCMMGAIGFLALPWIMHSTALSLVFLSIAAAGILTCSPL
HHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWSLPTAFLSGAAAATAIAMSNSIGNLAGFTSGYMIGYLRDVTQSGTSAYYMIAGMLVLG
HHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AFAIWTLPAKLVNR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]