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The map label for this gene is gstA [H]

Identifier: 73538554

GI number: 73538554

Start: 1429046

End: 1429657

Strand: Direct

Name: gstA [H]

Synonym: Reut_B4729

Alternate gene names: 73538554

Gene position: 1429046-1429657 (Clockwise)

Preceding gene: 73538553

Following gene: 73538555

Centisome position: 52.42

GC content: 67.97

Gene sequence:

>612_bases
ATGCAGATCTACCACCACCCGCTGTCCGGCCATTCGCATCGCGCCCGCCTCTTCCTGTCGCTGATCGATGTCCATGCCGA
GCCTGTCGAGGTCGACCTGGCCAGGCGCCAGCACAAGTCGCCCGAATTCCTCAAGCTCAATCCGTTCGGGCAGGTGCCGG
TCCTCGTCGACGGCGACACCGTGGTACCGGACTCCAACGCGATCATGGTCTACCTGGCCCGCAAGTTCGGCAGGACCGAC
TGGCTGCCTGAAGCGCCGGCCGCTGCCGCCGCCGTGCAGCGCTGGCTGTCCGTGGCCGCGGGCGATATTGCCTTCGGCCC
CGCCGCCGCGCGCCTGATCACCGTGTTCGGCGCGCCGCTGAACCGCGAGGAAGTCATCGCCCGTGCCCACGTGGTCATCA
AGCGCGTGGACGACGCGCTCGAAGGCCGCGAATGGATCGCCGCGGCGCAGCCGACGATTGCCGACGTGGCGCTCTACAGC
TATATCGCGCGCGCGCCGGAAGGCTTTGTCGACCTGGCGGAGTACGCCAATGTCAGGCGCTGGCTTGCGGCCGTGGAAGC
GCTGCCTGGCTTTATCGAGTTCAGGAAGAGCCCGGCCGGGCTCGAAGCCTGA

Upstream 100 bases:

>100_bases
GCACCTAAGATGGTTTGCAGCAGAACATCCCGCGCGCCGGCGGCAAGAATGCAGGCCGGCAGCGGCGCACACCATCACCG
TCGCAAAAGGGGCTTCTTCC

Downstream 100 bases:

>100_bases
AAACGCTACCTCGTCCGCCGGAGTCCGCACATGTCCACAAACCCCAGCCTCCCCTGGCACGCGGGCGAACTCGCGCTGCA
AGCCCGTGTCGGTGTCGCGG

Product: glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MQIYHHPLSGHSHRARLFLSLIDVHAEPVEVDLARRQHKSPEFLKLNPFGQVPVLVDGDTVVPDSNAIMVYLARKFGRTD
WLPEAPAAAAAVQRWLSVAAGDIAFGPAAARLITVFGAPLNREEVIARAHVVIKRVDDALEGREWIAAAQPTIADVALYS
YIARAPEGFVDLAEYANVRRWLAAVEALPGFIEFRKSPAGLEA

Sequences:

>Translated_203_residues
MQIYHHPLSGHSHRARLFLSLIDVHAEPVEVDLARRQHKSPEFLKLNPFGQVPVLVDGDTVVPDSNAIMVYLARKFGRTD
WLPEAPAAAAAVQRWLSVAAGDIAFGPAAARLITVFGAPLNREEVIARAHVVIKRVDDALEGREWIAAAQPTIADVALYS
YIARAPEGFVDLAEYANVRRWLAAVEALPGFIEFRKSPAGLEA
>Mature_203_residues
MQIYHHPLSGHSHRARLFLSLIDVHAEPVEVDLARRQHKSPEFLKLNPFGQVPVLVDGDTVVPDSNAIMVYLARKFGRTD
WLPEAPAAAAAVQRWLSVAAGDIAFGPAAARLITVFGAPLNREEVIARAHVVIKRVDDALEGREWIAAAQPTIADVALYS
YIARAPEGFVDLAEYANVRRWLAAVEALPGFIEFRKSPAGLEA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI124249394, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1788640, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864592, Length=197, Percent_Identity=29.4416243654822, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=28.7179487179487, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI85725204, Length=205, Percent_Identity=28.2926829268293, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737923, Length=205, Percent_Identity=28.2926829268293, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17864598, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17933730, Length=194, Percent_Identity=23.7113402061856, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45549270, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922532, Length=186, Percent_Identity=32.7956989247312, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864596, Length=195, Percent_Identity=24.1025641025641, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646249, Length=206, Percent_Identity=26.6990291262136, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922160, Length=193, Percent_Identity=28.4974093264249, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24654992, Length=186, Percent_Identity=30.6451612903226, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922526, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571670, Length=166, Percent_Identity=27.1084337349398, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130115, Length=188, Percent_Identity=32.4468085106383, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654979, Length=182, Percent_Identity=31.3186813186813, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221378983, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24646259, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24654965, Length=171, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922932, Length=200, Percent_Identity=26, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22261; Mature: 22261

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIYHHPLSGHSHRARLFLSLIDVHAEPVEVDLARRQHKSPEFLKLNPFGQVPVLVDGDT
CCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEECCCE
VVPDSNAIMVYLARKFGRTDWLPEAPAAAAAVQRWLSVAAGDIAFGPAAARLITVFGAPL
ECCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
NREEVIARAHVVIKRVDDALEGREWIAAAQPTIADVALYSYIARAPEGFVDLAEYANVRR
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WLAAVEALPGFIEFRKSPAGLEA
HHHHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MQIYHHPLSGHSHRARLFLSLIDVHAEPVEVDLARRQHKSPEFLKLNPFGQVPVLVDGDT
CCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEECCCE
VVPDSNAIMVYLARKFGRTDWLPEAPAAAAAVQRWLSVAAGDIAFGPAAARLITVFGAPL
ECCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
NREEVIARAHVVIKRVDDALEGREWIAAAQPTIADVALYSYIARAPEGFVDLAEYANVRR
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WLAAVEALPGFIEFRKSPAGLEA
HHHHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA