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The map label for this gene is mucK [H]

Identifier: 73538541

GI number: 73538541

Start: 1414091

End: 1415362

Strand: Direct

Name: mucK [H]

Synonym: Reut_B4716

Alternate gene names: 73538541

Gene position: 1414091-1415362 (Clockwise)

Preceding gene: 73538540

Following gene: 73538542

Centisome position: 51.87

GC content: 62.97

Gene sequence:

>1272_bases
ATGTCGTGGAAAGACCGCCCCTCTGCCGTGCTCACCGGCCTGCTCGCGATCCACCTGCTGGCGCATATCGACAGAAATAT
GCTGCTGGGTTTCTCGCCGCAGATCACCACTGACCTGGCGCTCAGCAATGCGCAATATGGCTTCCTGGTTGGCGCAGTCT
GGGTGCTCAGCTTTGGCGTCATGGCGTTGTTCATGGGTGCGCTTGCCGACCGGTTCAGCCGTACGCGCGTCATCGCTGCG
GGCGTGCTCGTGTGGAGTGCCTGCACATGGGCATCGGGCCATGCGGAAAGCTTCGAGCAAATGGTCATGGCGCGTTTCTT
CGTTGCGAGCGGCGAAGCCGCCCTGGTGCCCGCCGCCGTCGGCTTGCTGGCAGAGTTGTTTTCGGAGAAGCGCCGCAGCT
CAGCCATGGGTGTGTTCTTCATGGGCATCCCAATGGGAATCGGTTGCAGCTTCCTGCTGGCCGGCACGCTCGGCGCATCG
CACGGCTGGCGCAACACCTTCTACGTGCTGGGCGCCATCGGCGTGGGCATTGCCATCGTGCTGGCGTTCCTGAAAGACGA
GCGCGATCAACAGGCACATCAGGAGCGCGGCGCGCCTTTCGTGCGACAAGTGGCCAGTATCATGGCCGTCTTGCGCGAAC
GCCCTTCGCTGCGCCTCATCATCGCCGGCTTCGTGCTCGTACACATGCTCTTCGCCGGGCTCGCGTTCACGCAACTGTGG
CTGGCAAGGGAGCGGGGCATGGATGCTACCGGTATCGCCACGAACATCGGCATGCTGCAACTCCTGTTCGGCACGCTTGG
CTCCGTGGTGGGTGGTGTGCTGGGCGACCGGTTGGGCCGCCGCCTGCCGGGTTCGCAGGCGACATTGATGGCCCTGCTCG
TCGCGCTTTGCTCGGCGCCGATGATTGCCTACCGCTTCGCCGCCCCTGGCTCCGTCATCTTCTATGTCGGGATGTGTGCG
GGCTTCTTCCTGCCGCTGGCACTGTATGGTCCTGTGAACGCAGCGATCGTGAGCATGGTTCCGCAGCAGACCCGATCGAC
CATCTCGGGCTTCTCGATGCTCTGCATCAACGTGTTTGCGATCGCCATCGGCAATCTGGCGGTTGGCTGGGCGATCGACG
ACTTCGGTGCGCGCGGCATGCCAATGCCCATCACTCATATCTTGCTGGCAACCGACGTACTCGGGATCAGTTCAGCGTTG
CTCTTCGCGTTTGCCGCGCGCGCTTCGAGCCGGCAGCACATTTCTGGCAGCACTGTGAAATGGGTGCAATGA

Upstream 100 bases:

>100_bases
GCAGCCTGACCGGCACGACTCGTGCAACCTCGCGGCAACGCACCGCAGGTTGCCCTGGACGCGCCGTTGTGCGCGCCGAA
GCAAACAAGTGGAGACAACG

Downstream 100 bases:

>100_bases
GGAACACTGAAGACGGACGATCCACGACTGCCTCGGATTGTGCGGACAGGGTATTAGGCGACATCACGCGGCCTATCGGG
CGCCATCTCCTGCCTCGCCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSWKDRPSAVLTGLLAIHLLAHIDRNMLLGFSPQITTDLALSNAQYGFLVGAVWVLSFGVMALFMGALADRFSRTRVIAA
GVLVWSACTWASGHAESFEQMVMARFFVASGEAALVPAAVGLLAELFSEKRRSSAMGVFFMGIPMGIGCSFLLAGTLGAS
HGWRNTFYVLGAIGVGIAIVLAFLKDERDQQAHQERGAPFVRQVASIMAVLRERPSLRLIIAGFVLVHMLFAGLAFTQLW
LARERGMDATGIATNIGMLQLLFGTLGSVVGGVLGDRLGRRLPGSQATLMALLVALCSAPMIAYRFAAPGSVIFYVGMCA
GFFLPLALYGPVNAAIVSMVPQQTRSTISGFSMLCINVFAIAIGNLAVGWAIDDFGARGMPMPITHILLATDVLGISSAL
LFAFAARASSRQHISGSTVKWVQ

Sequences:

>Translated_423_residues
MSWKDRPSAVLTGLLAIHLLAHIDRNMLLGFSPQITTDLALSNAQYGFLVGAVWVLSFGVMALFMGALADRFSRTRVIAA
GVLVWSACTWASGHAESFEQMVMARFFVASGEAALVPAAVGLLAELFSEKRRSSAMGVFFMGIPMGIGCSFLLAGTLGAS
HGWRNTFYVLGAIGVGIAIVLAFLKDERDQQAHQERGAPFVRQVASIMAVLRERPSLRLIIAGFVLVHMLFAGLAFTQLW
LARERGMDATGIATNIGMLQLLFGTLGSVVGGVLGDRLGRRLPGSQATLMALLVALCSAPMIAYRFAAPGSVIFYVGMCA
GFFLPLALYGPVNAAIVSMVPQQTRSTISGFSMLCINVFAIAIGNLAVGWAIDDFGARGMPMPITHILLATDVLGISSAL
LFAFAARASSRQHISGSTVKWVQ
>Mature_422_residues
SWKDRPSAVLTGLLAIHLLAHIDRNMLLGFSPQITTDLALSNAQYGFLVGAVWVLSFGVMALFMGALADRFSRTRVIAAG
VLVWSACTWASGHAESFEQMVMARFFVASGEAALVPAAVGLLAELFSEKRRSSAMGVFFMGIPMGIGCSFLLAGTLGASH
GWRNTFYVLGAIGVGIAIVLAFLKDERDQQAHQERGAPFVRQVASIMAVLRERPSLRLIIAGFVLVHMLFAGLAFTQLWL
ARERGMDATGIATNIGMLQLLFGTLGSVVGGVLGDRLGRRLPGSQATLMALLVALCSAPMIAYRFAAPGSVIFYVGMCAG
FFLPLALYGPVNAAIVSMVPQQTRSTISGFSMLCINVFAIAIGNLAVGWAIDDFGARGMPMPITHILLATDVLGISSALL
FAFAARASSRQHISGSTVKWVQ

Specific function: Probable uptake of muconate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI215490102, Length=149, Percent_Identity=30.2013422818792, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI215490096, Length=149, Percent_Identity=30.2013422818792, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI14042968, Length=149, Percent_Identity=30.2013422818792, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI185136021, Length=147, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367379, Length=273, Percent_Identity=26.007326007326, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082071, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789515, Length=318, Percent_Identity=22.6415094339623, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI2367193, Length=398, Percent_Identity=25.3768844221106, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081723, Length=168, Percent_Identity=27.9761904761905, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17539092, Length=392, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209775, Length=195, Percent_Identity=24.6153846153846, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17557872, Length=283, Percent_Identity=26.1484098939929, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864456, Length=362, Percent_Identity=28.1767955801105, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24654039, Length=362, Percent_Identity=28.1767955801105, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24654037, Length=357, Percent_Identity=26.0504201680672, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24654041, Length=357, Percent_Identity=26.0504201680672, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24654044, Length=228, Percent_Identity=27.1929824561404, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640209, Length=155, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45011; Mature: 44880

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKDRPSAVLTGLLAIHLLAHIDRNMLLGFSPQITTDLALSNAQYGFLVGAVWVLSFGV
CCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
MALFMGALADRFSRTRVIAAGVLVWSACTWASGHAESFEQMVMARFFVASGEAALVPAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
GLLAELFSEKRRSSAMGVFFMGIPMGIGCSFLLAGTLGASHGWRNTFYVLGAIGVGIAIV
HHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LAFLKDERDQQAHQERGAPFVRQVASIMAVLRERPSLRLIIAGFVLVHMLFAGLAFTQLW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LARERGMDATGIATNIGMLQLLFGTLGSVVGGVLGDRLGRRLPGSQATLMALLVALCSAP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
MIAYRFAAPGSVIFYVGMCAGFFLPLALYGPVNAAIVSMVPQQTRSTISGFSMLCINVFA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIGNLAVGWAIDDFGARGMPMPITHILLATDVLGISSALLFAFAARASSRQHISGSTVK
HHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
WVQ
CCC
>Mature Secondary Structure 
SWKDRPSAVLTGLLAIHLLAHIDRNMLLGFSPQITTDLALSNAQYGFLVGAVWVLSFGV
CCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
MALFMGALADRFSRTRVIAAGVLVWSACTWASGHAESFEQMVMARFFVASGEAALVPAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
GLLAELFSEKRRSSAMGVFFMGIPMGIGCSFLLAGTLGASHGWRNTFYVLGAIGVGIAIV
HHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LAFLKDERDQQAHQERGAPFVRQVASIMAVLRERPSLRLIIAGFVLVHMLFAGLAFTQLW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LARERGMDATGIATNIGMLQLLFGTLGSVVGGVLGDRLGRRLPGSQATLMALLVALCSAP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
MIAYRFAAPGSVIFYVGMCAGFFLPLALYGPVNAAIVSMVPQQTRSTISGFSMLCINVFA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIGNLAVGWAIDDFGARGMPMPITHILLATDVLGISSALLFAFAARASSRQHISGSTVK
HHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
WVQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]