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The map label for this gene is pyc [H]

Identifier: 73538542

GI number: 73538542

Start: 1415720

End: 1419229

Strand: Direct

Name: pyc [H]

Synonym: Reut_B4717

Alternate gene names: 73538542

Gene position: 1415720-1419229 (Clockwise)

Preceding gene: 73538541

Following gene: 73538544

Centisome position: 51.93

GC content: 65.47

Gene sequence:

>3510_bases
ATGAACTACACCCCAATCAAATCCCTGCTGATTGCCAACCGATCCGAAATCGCGATTCGCGTGATGCGCGCCGCCGCCGA
GATGAACATCCGCACGGTTGCGATCTATTCGAAGGAAGACCGGCTCGCGCTCCATCGCTTCAAGGCCGATGAAAGCTACC
TTGTCGGCGAGGGCAAGAAGCCGCTGGCGGCCTACCTCGATATCGACGACATCTTGCGCATTGCGCGCCAGGCGAAGGTC
GACGCCATTCACCCGGGCTACGGCTTCCTCTCGGAGAACCCTGATTTCGCGCAGGCCGTGATGGATGCCGGTATCCGCTG
GATCGGCCCGTCGCCCGATGTCATGCGCAAGCTCGGCAACAAGGTCGCGGCGCGCAATGCCGCGATCGAGGCGGGCGTGC
CGGTGATGCCGGCCACCGACCCGTTGCCGCAAGATCTGGACGAGTGCAAGCGCCTGGCAGCCGGCATCGGCTATCCGCTA
ATGCTCAAGGCGAGCTGGGGTGGCGGCGGACGCGGCATGCGTATGCTGGAGAATGAACAGGATCTCGAAACGTTGCTGCC
GGCGGCAAGGCGGGAGGCGCTGGCTGCGTTCGGCAACGATGAGGTCTATGTCGAGAAACTGGTACGCAATGCGCGCCACG
TCGAAGTGCAGGCGCTCGGCGATACGCATGGCAACCTGGTGCACCTGTACGAGCGCGATTGTACCGTGCAGCGGCGCAAC
CAGAAGGTGGTGGAGCGCGCGCCTGCGCCATACCTCGACGCCGCCGGTCGCGCAGCACTGTGCGACGCGGCGATGCGGCT
GATGCGCGCGGTCGGCTACACGCATGCGGGCACGATCGAATTCCTGATGGATGCCGACTCCGGCCAGTTCTACTTCATCG
AAGTCAATCCGCGCATCCAGGTCGAGCACACGGTCACCGAGATGGTCACCGGCGTCGATATCGTCAAGGCGCAGATCCGC
ATCACTGAAGGCGGCCATATCGGCATGACCGAGAACACGCGCGACGCTGAGGGCAAGATCGTGGTGCGCGCTGCGGGTGT
GCCGGAACAGTCGGGGATTTCGCTGAACGGGCATGCCTTGCAATGCCGGATCACCACAGAGGACCCTGAGAACGGCTTCC
TGCCCGACTATGGCCGCCTGTCCGCGTATCGCAGCGCCGCAGGCTTCGGCGTGCGGCTCGATGCCGGCACCGCCTACGGC
GGCGCGGTGATCACGCCCTACTACGATTCGCTGCTGGTCAAGGTCACGACCTGGGCGCCCACTGCTCCCGAGTCGATCCG
GCGCATGGACCGCGCGCTGCGCGAGTTCCGCATCCGCGGCGTCGCGTCCAACCTGCAGTTCCTCGAGAACGTCATCAACC
ACCCATCGTTCAAGGCCGGTGACGTCACCACGCGCTTTATCGACAAGACGCCCGAACTGCTGGCGTTCACCAAGCGGCAG
GATCGCGCGACCAAGCTGCTGCACTATCTCGGCGATGTCTGCGTCAATGGCCATCCAGAAATGGCGGGCCGCTCGCTGCC
GTCCTTGCCACTGCCCGCACCGGTGCTTCCCTCGGTAGACGCAACGAGCCCGGTGCCGACCGGCACGCGCGATCTGCTGC
GCGAGCTTGGTGCAGAGAAGTTCTCGCAATGGATGCTCGAGCAGAAGCGGGTGCTGCTGACCGACACCACCATGCGCGAT
GCGCACCAGTCGCTGTTCGCCACGCGCATGCGCACCGCCGACATGCTGCCGATCGCGCCGTTCTACGCGCGCGAACTGCC
GCAGCTGTTCTCGATGGAGTGCTGGGGTGGCGCGACGTTCGATGTGGCGCTGCGCTTCCTCAAGGAAGACCCGTGGCAGC
GTCTCGAGCAACTGCGCGAGCGGGTGCCGAACATCCTGTTCCAGATGCTGTTGCGCGGCTCGAACGCGGTCGGCTACACC
AACTACGCGGACAACGTGGTGAAGTTCTTCGTGCGCCAGGCCGCCAGCGCCGGCGTGGACGTGTTCCGCGTGTTCGATTC
CCTGAACTGGGTGCGCAATATGCGCGTGGCCATCGATGCCGTGGGCGAAAGCGGCGCGCTATGCGAAGGCGCGATCTGCT
ACACCGGCGACGTCTTCGACGGCTCCCGTCCCAAGTACGACCTGAAGTACTACGTCGGCATCGCGCGCGAGCTGAAGCAG
GCCGGCGTGCATGTGCTGGGCATCAAGGACATGGCCGGCATCTGCCGTCCGCAAGCGGCGGCCGCGCTGGTCAAGGCGCT
CAAGGAAGAGACCGGCCTGCCCGTGCACTTCCATACCCACGACACCAGCGGCATCTCGGCCGCGTCCGCGCTGGCCGCCA
TCGAGGCAGGCTGCGATGCAGTGGATGGTGCGCTCGATGCCATGAGCGGACTGACGTCGCAACCGAACCTGTCTAGCATC
GCGGCGGCGCTGGCCGGCAGCGAGCGCGACCCGGGGCTCAGCCTGGAGCGGCTGCACGAGGCGTCGATGTACTGGGAAGG
CGTGCGTCGCTACTACGCGCCGTTCGAGTCGGAAATCCGCGCGGGTACCGCCGATGTCTACCGCCACGAAATGCCCGGCG
GCCAGTACACCAACCTGCGCGAGCAGGCACGTTCGCTCGGTATCGAGCATCGCTGGACCGAGGTGTCGCGCGCGTACGCA
GACGTCAACAAGATGTTCGGCGATATCGTGAAGGTGACGCCGACTTCAAAGGTAGTCGGCGACATGGCGCTGATGATGGT
CGCCAACGACATGAGCGCAGCCGACGTCTGCGATCCGGCCCGCGAAGTTGCCTTCCCCGAATCGGTGGTCTCGCTGTTCA
AGGGCGAGCTGGGCTTCCCGCCCGACGGCTTCCCCGCGGAACTGTCGCGCAAGGTGCTGCGCGGCGAGCCGCCCGCACCT
TACCGCCCGGGCGACCAGATTCCGGCGGTTGACCTCGAGGCAGCGCGCGCCGAAGCCAGCGCGGCGTGCGAACAGCCTGT
CGACGACCGCCAGCTGGCGTCGTACCTGATGTATCCCAAGCAGGCCGTTGCTTATCACGCGCACGTGCGCACCTACAGCG
ATACCTCGGTGGTGCCGACGCCGGCCTTCCTGTACGGCCTGCAGCCACAGGAAGAAGTGGGCATCGACATCGAGCCGGGC
AAGACGCTGCTGGTATCGCTGCAGGGCACGCATGCCGACGCGGAAGAGGGCAACATCAAGGTCCAGTTCGAACTGAACGG
GCAGTCGCGCACGGCGGTGATCGAGCAGCGCAGCACCGTGCAGGCCGGTACGTCACGCCACAGCCGTCCGGTTGCGGACC
CTGAGAATCCGCTGCATATCGCCGCGCCGATGCCAGGCTCGATCGTGACCGTAGCGGTCCAGCCGGGCCAACGCGTGGCG
GCGGGCACGACGCTGATTGCGTTGGAAGCCATGAAGATGGAAACCCACATCGCGGCTGAGCGCGACTGTGAGATCGCGGC
CGTGCATGTGAAGTCTGGTGACCGGGTGTCGGCGAAGGATCTGCTGATCGAGCTGAAGGGAACGGAGTAA

Upstream 100 bases:

>100_bases
CCCGACCAACCTCCGCTTATTCGACCCAATGGCGGAGACCACCGCACCCGATTGACCATGAGGGCCACCTGAACCCTGGC
CGACCCTTCCTTTGTGCGCT

Downstream 100 bases:

>100_bases
CCCCGGGCGGCAGCCAGCCAGCGTCTCAGCTGGCTGCCTGCCGCTTTTCCATCTCTAATCCGCGAACAGTTCGACAAACT
GATTGCGCAGCCACTGGTTT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1169; Mature: 1169

Protein sequence:

>1169_residues
MNYTPIKSLLIANRSEIAIRVMRAAAEMNIRTVAIYSKEDRLALHRFKADESYLVGEGKKPLAAYLDIDDILRIARQAKV
DAIHPGYGFLSENPDFAQAVMDAGIRWIGPSPDVMRKLGNKVAARNAAIEAGVPVMPATDPLPQDLDECKRLAAGIGYPL
MLKASWGGGGRGMRMLENEQDLETLLPAARREALAAFGNDEVYVEKLVRNARHVEVQALGDTHGNLVHLYERDCTVQRRN
QKVVERAPAPYLDAAGRAALCDAAMRLMRAVGYTHAGTIEFLMDADSGQFYFIEVNPRIQVEHTVTEMVTGVDIVKAQIR
ITEGGHIGMTENTRDAEGKIVVRAAGVPEQSGISLNGHALQCRITTEDPENGFLPDYGRLSAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAPESIRRMDRALREFRIRGVASNLQFLENVINHPSFKAGDVTTRFIDKTPELLAFTKRQ
DRATKLLHYLGDVCVNGHPEMAGRSLPSLPLPAPVLPSVDATSPVPTGTRDLLRELGAEKFSQWMLEQKRVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYARELPQLFSMECWGGATFDVALRFLKEDPWQRLEQLRERVPNILFQMLLRGSNAVGYT
NYADNVVKFFVRQAASAGVDVFRVFDSLNWVRNMRVAIDAVGESGALCEGAICYTGDVFDGSRPKYDLKYYVGIARELKQ
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
AAALAGSERDPGLSLERLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNKMFGDIVKVTPTSKVVGDMALMMVANDMSAADVCDPAREVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDQIPAVDLEAARAEASAACEQPVDDRQLASYLMYPKQAVAYHAHVRTYSDTSVVPTPAFLYGLQPQEEVGIDIEPG
KTLLVSLQGTHADAEEGNIKVQFELNGQSRTAVIEQRSTVQAGTSRHSRPVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLIALEAMKMETHIAAERDCEIAAVHVKSGDRVSAKDLLIELKGTE

Sequences:

>Translated_1169_residues
MNYTPIKSLLIANRSEIAIRVMRAAAEMNIRTVAIYSKEDRLALHRFKADESYLVGEGKKPLAAYLDIDDILRIARQAKV
DAIHPGYGFLSENPDFAQAVMDAGIRWIGPSPDVMRKLGNKVAARNAAIEAGVPVMPATDPLPQDLDECKRLAAGIGYPL
MLKASWGGGGRGMRMLENEQDLETLLPAARREALAAFGNDEVYVEKLVRNARHVEVQALGDTHGNLVHLYERDCTVQRRN
QKVVERAPAPYLDAAGRAALCDAAMRLMRAVGYTHAGTIEFLMDADSGQFYFIEVNPRIQVEHTVTEMVTGVDIVKAQIR
ITEGGHIGMTENTRDAEGKIVVRAAGVPEQSGISLNGHALQCRITTEDPENGFLPDYGRLSAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAPESIRRMDRALREFRIRGVASNLQFLENVINHPSFKAGDVTTRFIDKTPELLAFTKRQ
DRATKLLHYLGDVCVNGHPEMAGRSLPSLPLPAPVLPSVDATSPVPTGTRDLLRELGAEKFSQWMLEQKRVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYARELPQLFSMECWGGATFDVALRFLKEDPWQRLEQLRERVPNILFQMLLRGSNAVGYT
NYADNVVKFFVRQAASAGVDVFRVFDSLNWVRNMRVAIDAVGESGALCEGAICYTGDVFDGSRPKYDLKYYVGIARELKQ
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
AAALAGSERDPGLSLERLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNKMFGDIVKVTPTSKVVGDMALMMVANDMSAADVCDPAREVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDQIPAVDLEAARAEASAACEQPVDDRQLASYLMYPKQAVAYHAHVRTYSDTSVVPTPAFLYGLQPQEEVGIDIEPG
KTLLVSLQGTHADAEEGNIKVQFELNGQSRTAVIEQRSTVQAGTSRHSRPVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLIALEAMKMETHIAAERDCEIAAVHVKSGDRVSAKDLLIELKGTE
>Mature_1169_residues
MNYTPIKSLLIANRSEIAIRVMRAAAEMNIRTVAIYSKEDRLALHRFKADESYLVGEGKKPLAAYLDIDDILRIARQAKV
DAIHPGYGFLSENPDFAQAVMDAGIRWIGPSPDVMRKLGNKVAARNAAIEAGVPVMPATDPLPQDLDECKRLAAGIGYPL
MLKASWGGGGRGMRMLENEQDLETLLPAARREALAAFGNDEVYVEKLVRNARHVEVQALGDTHGNLVHLYERDCTVQRRN
QKVVERAPAPYLDAAGRAALCDAAMRLMRAVGYTHAGTIEFLMDADSGQFYFIEVNPRIQVEHTVTEMVTGVDIVKAQIR
ITEGGHIGMTENTRDAEGKIVVRAAGVPEQSGISLNGHALQCRITTEDPENGFLPDYGRLSAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAPESIRRMDRALREFRIRGVASNLQFLENVINHPSFKAGDVTTRFIDKTPELLAFTKRQ
DRATKLLHYLGDVCVNGHPEMAGRSLPSLPLPAPVLPSVDATSPVPTGTRDLLRELGAEKFSQWMLEQKRVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYARELPQLFSMECWGGATFDVALRFLKEDPWQRLEQLRERVPNILFQMLLRGSNAVGYT
NYADNVVKFFVRQAASAGVDVFRVFDSLNWVRNMRVAIDAVGESGALCEGAICYTGDVFDGSRPKYDLKYYVGIARELKQ
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
AAALAGSERDPGLSLERLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNKMFGDIVKVTPTSKVVGDMALMMVANDMSAADVCDPAREVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDQIPAVDLEAARAEASAACEQPVDDRQLASYLMYPKQAVAYHAHVRTYSDTSVVPTPAFLYGLQPQEEVGIDIEPG
KTLLVSLQGTHADAEEGNIKVQFELNGQSRTAVIEQRSTVQAGTSRHSRPVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLIALEAMKMETHIAAERDCEIAAVHVKSGDRVSAKDLLIELKGTE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1180, Percent_Identity=47.8813559322034, Blast_Score=1069, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1180, Percent_Identity=47.8813559322034, Blast_Score=1069, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1180, Percent_Identity=47.8813559322034, Blast_Score=1069, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=486, Percent_Identity=41.5637860082305, Blast_Score=375, Evalue=1e-103,
Organism=Homo sapiens, GI65506442, Length=471, Percent_Identity=40.7643312101911, Blast_Score=348, Evalue=1e-95,
Organism=Homo sapiens, GI295821183, Length=471, Percent_Identity=40.7643312101911, Blast_Score=348, Evalue=2e-95,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=41.1637931034483, Blast_Score=348, Evalue=3e-95,
Organism=Homo sapiens, GI134142062, Length=507, Percent_Identity=32.741617357002, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI38679960, Length=531, Percent_Identity=31.4500941619586, Blast_Score=241, Evalue=4e-63,
Organism=Homo sapiens, GI38679977, Length=531, Percent_Identity=31.4500941619586, Blast_Score=240, Evalue=6e-63,
Organism=Homo sapiens, GI38679967, Length=531, Percent_Identity=31.4500941619586, Blast_Score=240, Evalue=6e-63,
Organism=Homo sapiens, GI38679971, Length=531, Percent_Identity=31.4500941619586, Blast_Score=240, Evalue=7e-63,
Organism=Homo sapiens, GI38679974, Length=531, Percent_Identity=31.4500941619586, Blast_Score=240, Evalue=7e-63,
Organism=Escherichia coli, GI1789654, Length=465, Percent_Identity=41.9354838709677, Blast_Score=347, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17562816, Length=1172, Percent_Identity=48.3788395904437, Blast_Score=1085, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=475, Percent_Identity=44.2105263157895, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=469, Percent_Identity=40.5117270788913, Blast_Score=339, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI71997163, Length=515, Percent_Identity=29.7087378640777, Blast_Score=218, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=515, Percent_Identity=29.7087378640777, Blast_Score=217, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI133931226, Length=502, Percent_Identity=29.0836653386454, Blast_Score=201, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1174, Percent_Identity=45.5706984667802, Blast_Score=991, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1178, Percent_Identity=46.0101867572156, Blast_Score=981, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=463, Percent_Identity=37.7969762419007, Blast_Score=321, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6324343, Length=519, Percent_Identity=31.7919075144509, Blast_Score=233, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6323863, Length=438, Percent_Identity=32.1917808219178, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI24652212, Length=1169, Percent_Identity=48.2463644140291, Blast_Score=1078, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1169, Percent_Identity=48.2463644140291, Blast_Score=1078, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1169, Percent_Identity=48.2463644140291, Blast_Score=1078, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1169, Percent_Identity=48.2463644140291, Blast_Score=1078, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1169, Percent_Identity=48.2463644140291, Blast_Score=1078, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1185, Percent_Identity=47.7637130801688, Blast_Score=1070, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1185, Percent_Identity=47.7637130801688, Blast_Score=1070, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1185, Percent_Identity=47.7637130801688, Blast_Score=1070, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1185, Percent_Identity=47.7637130801688, Blast_Score=1070, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1185, Percent_Identity=47.7637130801688, Blast_Score=1070, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=475, Percent_Identity=41.6842105263158, Blast_Score=356, Evalue=6e-98,
Organism=Drosophila melanogaster, GI24651759, Length=436, Percent_Identity=41.0550458715596, Blast_Score=316, Evalue=6e-86,
Organism=Drosophila melanogaster, GI161076407, Length=502, Percent_Identity=30.6772908366534, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24586460, Length=502, Percent_Identity=30.6772908366534, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24586458, Length=502, Percent_Identity=30.6772908366534, Blast_Score=217, Evalue=3e-56,
Organism=Drosophila melanogaster, GI161076409, Length=502, Percent_Identity=30.6772908366534, Blast_Score=217, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127718; Mature: 127718

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYTPIKSLLIANRSEIAIRVMRAAAEMNIRTVAIYSKEDRLALHRFKADESYLVGEGKK
CCCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCCCEEECCCCC
PLAAYLDIDDILRIARQAKVDAIHPGYGFLSENPDFAQAVMDAGIRWIGPSPDVMRKLGN
CEEEECCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHH
KVAARNAAIEAGVPVMPATDPLPQDLDECKRLAAGIGYPLMLKASWGGGGRGMRMLENEQ
HHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCH
DLETLLPAARREALAAFGNDEVYVEKLVRNARHVEVQALGDTHGNLVHLYERDCTVQRRN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCHHHHHH
QKVVERAPAPYLDAAGRAALCDAAMRLMRAVGYTHAGTIEFLMDADSGQFYFIEVNPRIQ
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCEEE
VEHTVTEMVTGVDIVKAQIRITEGGHIGMTENTRDAEGKIVVRAAGVPEQSGISLNGHAL
EHHHHHHHHHCHHEEEEEEEEECCCEECCCCCCCCCCCEEEEEECCCCCCCCEEECCCEE
QCRITTEDPENGFLPDYGRLSAYRSAAGFGVRLDAGTAYGGAVITPYYDSLLVKVTTWAP
EEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCC
TAPESIRRMDRALREFRIRGVASNLQFLENVINHPSFKAGDVTTRFIDKTPELLAFTKRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHH
DRATKLLHYLGDVCVNGHPEMAGRSLPSLPLPAPVLPSVDATSPVPTGTRDLLRELGAEK
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHH
FSQWMLEQKRVLLTDTTMRDAHQSLFATRMRTADMLPIAPFYARELPQLFSMECWGGATF
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHH
DVALRFLKEDPWQRLEQLRERVPNILFQMLLRGSNAVGYTNYADNVVKFFVRQAASAGVD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VFRVFDSLNWVRNMRVAIDAVGESGALCEGAICYTGDVFDGSRPKYDLKYYVGIARELKQ
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDA
CCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCH
VDGALDAMSGLTSQPNLSSIAAALAGSERDPGLSLERLHEASMYWEGVRRYYAPFESEIR
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHC
AGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYADVNKMFGDIVKVTPTSKVVG
CCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
DMALMMVANDMSAADVCDPAREVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
HHHHHHHCCCCCHHHHCCHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
YRPGDQIPAVDLEAARAEASAACEQPVDDRQLASYLMYPKQAVAYHAHVRTYSDTSVVPT
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHEEHHEEEECCCCCCCC
PAFLYGLQPQEEVGIDIEPGKTLLVSLQGTHADAEEGNIKVQFELNGQSRTAVIEQRSTV
CHHHCCCCCHHHCCCEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEHHHHHHH
QAGTSRHSRPVADPENPLHIAAPMPGSIVTVAVQPGQRVAAGTTLIALEAMKMETHIAAE
HHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEECCCCEEEEHHHHHHHHHHCCC
RDCEIAAVHVKSGDRVSAKDLLIELKGTE
CCCEEEEEEECCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MNYTPIKSLLIANRSEIAIRVMRAAAEMNIRTVAIYSKEDRLALHRFKADESYLVGEGKK
CCCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCCCEEECCCCC
PLAAYLDIDDILRIARQAKVDAIHPGYGFLSENPDFAQAVMDAGIRWIGPSPDVMRKLGN
CEEEECCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHH
KVAARNAAIEAGVPVMPATDPLPQDLDECKRLAAGIGYPLMLKASWGGGGRGMRMLENEQ
HHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCH
DLETLLPAARREALAAFGNDEVYVEKLVRNARHVEVQALGDTHGNLVHLYERDCTVQRRN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCHHHHHH
QKVVERAPAPYLDAAGRAALCDAAMRLMRAVGYTHAGTIEFLMDADSGQFYFIEVNPRIQ
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCEEE
VEHTVTEMVTGVDIVKAQIRITEGGHIGMTENTRDAEGKIVVRAAGVPEQSGISLNGHAL
EHHHHHHHHHCHHEEEEEEEEECCCEECCCCCCCCCCCEEEEEECCCCCCCCEEECCCEE
QCRITTEDPENGFLPDYGRLSAYRSAAGFGVRLDAGTAYGGAVITPYYDSLLVKVTTWAP
EEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCC
TAPESIRRMDRALREFRIRGVASNLQFLENVINHPSFKAGDVTTRFIDKTPELLAFTKRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHH
DRATKLLHYLGDVCVNGHPEMAGRSLPSLPLPAPVLPSVDATSPVPTGTRDLLRELGAEK
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHH
FSQWMLEQKRVLLTDTTMRDAHQSLFATRMRTADMLPIAPFYARELPQLFSMECWGGATF
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHH
DVALRFLKEDPWQRLEQLRERVPNILFQMLLRGSNAVGYTNYADNVVKFFVRQAASAGVD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VFRVFDSLNWVRNMRVAIDAVGESGALCEGAICYTGDVFDGSRPKYDLKYYVGIARELKQ
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDA
CCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCH
VDGALDAMSGLTSQPNLSSIAAALAGSERDPGLSLERLHEASMYWEGVRRYYAPFESEIR
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHC
AGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYADVNKMFGDIVKVTPTSKVVG
CCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
DMALMMVANDMSAADVCDPAREVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
HHHHHHHCCCCCHHHHCCHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
YRPGDQIPAVDLEAARAEASAACEQPVDDRQLASYLMYPKQAVAYHAHVRTYSDTSVVPT
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHEEHHEEEECCCCCCCC
PAFLYGLQPQEEVGIDIEPGKTLLVSLQGTHADAEEGNIKVQFELNGQSRTAVIEQRSTV
CHHHCCCCCHHHCCCEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEHHHHHHH
QAGTSRHSRPVADPENPLHIAAPMPGSIVTVAVQPGQRVAAGTTLIALEAMKMETHIAAE
HHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEECCCCEEEEHHHHHHHHHHCCC
RDCEIAAVHVKSGDRVSAKDLLIELKGTE
CCCEEEEEEECCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]