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The map label for this gene is aaeR [H]

Identifier: 73538511

GI number: 73538511

Start: 1382461

End: 1383366

Strand: Direct

Name: aaeR [H]

Synonym: Reut_B4685

Alternate gene names: 73538511

Gene position: 1382461-1383366 (Clockwise)

Preceding gene: 73538509

Following gene: 73538512

Centisome position: 50.71

GC content: 64.79

Gene sequence:

>906_bases
TTGCAAGACCTGAATGACCTCTACTTCTACGTCCAGGCCGTCGACCACGGGGGTTTTGCCCCAGCCGGTCGAGCGCTCGG
CATGCCCAAGTCACGGCTCAGCCGCCGCATGGCGATACTGGAAGAACGGCTAGGGGTGCGCCTCATCCAGCGCTCCACGC
GTCGCTTCGCCGTTACCGAGATCGGCCGCATTTACTACGAACACTGCAAGGCTATGCTGTTGCAGGCTGAGGCCGCGCAG
GAAGCCATCGAAGTCACACGCGCCGAGCCACGCGGCACAGTGCGTGTGACCTGTCCGGTCGCGTTACTTCAGGCGCACGT
TGGTGTCATGCTCGGCGAGTTCATGGCAAGGCATCCGCTGGTGACGATCCATCTGGAGGCCACCAATCGCCGGGTCGATC
CGGTGGCGGAGGCCATCGACGTAGCCATCCGCGTTCGGCCGCCCCCGCTTGAGGACAGCGACCTCGTCATCCGACCGCTG
GCCGAGCGCAGCCAGTGTCTGATTGCCAGTCCTTCACTGGTACAAGCCTTCGGCATGCCGCAGTTTCCCGTCGCGCTGCA
TGACTGGCCCAGCCTGGCAATCGGCACCCCGCAGAGCGACCACGCGTGGAAGCTGTTTGGCCCCGATGGGGAGCAAGCCA
CCATCCACCACATCCCGCGCTATATCACCGGTGACATGATCGCCGCGCGCAACGCGGCGATTGCGGGCGTCGGGGTCTGC
CAGTTGCCGGTCATGATGGTGCGCGATCAATTGGCCGAAGGCTCGCTGGTGCGGGTGTTGCCGGGCTGGGCACCACGGCG
CGAGATTCTGCATGTCGTCTTCGCGTCGCGGCGCGGCCTGTTGCCGGCCGTCAGGATGCTGATCGACCATCTGGCCGACC
GTTTCGGACAGATGGACGAGGATTAG

Upstream 100 bases:

>100_bases
ATTGCTTCATTCGATGGACAAAGCATAGTATTAGGACGAAGGTGGCTCTAGATGCTGAATTCGCGCATGAGAGTCCTGTT
ATGTGAACGGTGAGAGCCAC

Downstream 100 bases:

>100_bases
CCGCCAACGCCCTTTCGAGAGCACTGCGCGAGCCATTCAGCGGCCTGCTGCCCCCGGCAGCCCGGCGCCCAAACAACCCA
TCGTTGCAGCCATGGGACTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQDLNDLYFYVQAVDHGGFAPAGRALGMPKSRLSRRMAILEERLGVRLIQRSTRRFAVTEIGRIYYEHCKAMLLQAEAAQ
EAIEVTRAEPRGTVRVTCPVALLQAHVGVMLGEFMARHPLVTIHLEATNRRVDPVAEAIDVAIRVRPPPLEDSDLVIRPL
AERSQCLIASPSLVQAFGMPQFPVALHDWPSLAIGTPQSDHAWKLFGPDGEQATIHHIPRYITGDMIAARNAAIAGVGVC
QLPVMMVRDQLAEGSLVRVLPGWAPRREILHVVFASRRGLLPAVRMLIDHLADRFGQMDED

Sequences:

>Translated_301_residues
MQDLNDLYFYVQAVDHGGFAPAGRALGMPKSRLSRRMAILEERLGVRLIQRSTRRFAVTEIGRIYYEHCKAMLLQAEAAQ
EAIEVTRAEPRGTVRVTCPVALLQAHVGVMLGEFMARHPLVTIHLEATNRRVDPVAEAIDVAIRVRPPPLEDSDLVIRPL
AERSQCLIASPSLVQAFGMPQFPVALHDWPSLAIGTPQSDHAWKLFGPDGEQATIHHIPRYITGDMIAARNAAIAGVGVC
QLPVMMVRDQLAEGSLVRVLPGWAPRREILHVVFASRRGLLPAVRMLIDHLADRFGQMDED
>Mature_301_residues
MQDLNDLYFYVQAVDHGGFAPAGRALGMPKSRLSRRMAILEERLGVRLIQRSTRRFAVTEIGRIYYEHCKAMLLQAEAAQ
EAIEVTRAEPRGTVRVTCPVALLQAHVGVMLGEFMARHPLVTIHLEATNRRVDPVAEAIDVAIRVRPPPLEDSDLVIRPL
AERSQCLIASPSLVQAFGMPQFPVALHDWPSLAIGTPQSDHAWKLFGPDGEQATIHHIPRYITGDMIAARNAAIAGVGVC
QLPVMMVRDQLAEGSLVRVLPGWAPRREILHVVFASRRGLLPAVRMLIDHLADRFGQMDED

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=27.9461279461279, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=29.0102389078498, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=26.5573770491803, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=27.4834437086093, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081978, Length=302, Percent_Identity=26.8211920529801, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=22.4137931034483, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=26.2798634812287, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=161, Percent_Identity=27.9503105590062, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788706, Length=146, Percent_Identity=28.7671232876712, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33385; Mature: 33385

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDLYFYVQAVDHGGFAPAGRALGMPKSRLSRRMAILEERLGVRLIQRSTRRFAVTE
CCCHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRIYYEHCKAMLLQAEAAQEAIEVTRAEPRGTVRVTCPVALLQAHVGVMLGEFMARHPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCE
VTIHLEATNRRVDPVAEAIDVAIRVRPPPLEDSDLVIRPLAERSQCLIASPSLVQAFGMP
EEEEEECCCCCCHHHHHHHEEEEEECCCCCCCCCEEEEECCCCCCEEEECCHHHHHHCCC
QFPVALHDWPSLAIGTPQSDHAWKLFGPDGEQATIHHIPRYITGDMIAARNAAIAGVGVC
CCCEEECCCCCEEECCCCCCCEEEEECCCCCCHHHHHCCHHHHCCHHHHCCCHHCCCHHH
QLPVMMVRDQLAEGSLVRVLPGWAPRREILHVVFASRRGLLPAVRMLIDHLADRFGQMDE
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
D
C
>Mature Secondary Structure
MQDLNDLYFYVQAVDHGGFAPAGRALGMPKSRLSRRMAILEERLGVRLIQRSTRRFAVTE
CCCHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRIYYEHCKAMLLQAEAAQEAIEVTRAEPRGTVRVTCPVALLQAHVGVMLGEFMARHPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCE
VTIHLEATNRRVDPVAEAIDVAIRVRPPPLEDSDLVIRPLAERSQCLIASPSLVQAFGMP
EEEEEECCCCCCHHHHHHHEEEEEECCCCCCCCCEEEEECCCCCCEEEECCHHHHHHCCC
QFPVALHDWPSLAIGTPQSDHAWKLFGPDGEQATIHHIPRYITGDMIAARNAAIAGVGVC
CCCEEECCCCCEEECCCCCCCEEEEECCCCCCHHHHHCCHHHHCCHHHHCCCHHCCCHHH
QLPVMMVRDQLAEGSLVRVLPGWAPRREILHVVFASRRGLLPAVRMLIDHLADRFGQMDE
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]