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The map label for this gene is est [H]

Identifier: 73538487

GI number: 73538487

Start: 1352808

End: 1353707

Strand: Reverse

Name: est [H]

Synonym: Reut_B4661

Alternate gene names: 73538487

Gene position: 1353707-1352808 (Counterclockwise)

Preceding gene: 73538488

Following gene: 73538486

Centisome position: 49.66

GC content: 61.0

Gene sequence:

>900_bases
GTGGATGGACAGTTCTTGGGTGGCGATGCTACGGGTTCTTGCAATACAGTTGCAGCCCTATTGATCCACGGTCTCGGCGG
TACCGAACATGAGCTTCGGCTTGTCGAGAAGACGCTGAAGGCGGAAGGATACGAAACAAAGTGCGCCGTACTGCCCGGGC
ATGGTACACGCCCGGAGGATCTGGTCGGCGTAAGGTTCGAGCAGTGGCTTGAGGCCGTATCGGTCGAATATCTCGAACTG
CGCGCCAGGCACGATACCGTCCACATCGTCGGCATGTGCATGGGTGCGTTGCTGGCGCTTGCGTTGAGCCAGTTGATCGG
CGACAGGCGCGGCCGCGTCGTCGCACTGGCAGCACCTGTATTCCTCGACGGCTGGTCTCTGCCCTGGTATCGCGGCTTGC
GGCATCTGGTGTACCGTCTGCCGCGAGCCCGCGACAAATTCCGCGTGAAGGAATCCGAGCCGTTCGGTGTCAAGAACGGC
GTATTGCGCGCGGCAATCAAGGCTCGCTTCCTGCGAGGCGACACGTTTCACTATTCGTGGACGCCGCTCACTTGCATCCG
CGAACTGGATCGCCTGCGCAGCTACGTCCGCAAGCGCGTACGGCGCGTTAGCCGGCCAGCACTGATTATTCACGCTCGCG
AAGATGAGTTGACGAGCCTGCGATCGGCCTACTTTCTCAGCAAGCACATTCGCGCGGCCAAGTTGCTCGTCGTGGACGAG
AGCTACCACATGCTGAGCATCGACAACGATCGCAGGCTGGTCGCCAGCACTGTCGCGCAGTTTCTCCGCGAAGACGAGAA
CAGTGGACAGAACTTCGGCACCGCGCTGAGGGGCGTCTTTGCCGAACCCGCGAACGAGCCATTCGAGGCATTGGTCGGTA
TCTCCCTGGCCGCCGAATAG

Upstream 100 bases:

>100_bases
CGAGATGACGGCTCGTTTCGTTTACAAACAATTACGTGCTGAGTAGCGAAGGCGCCGCACGGAGACACAGTGCGGTACCT
GGAATAAAGTGAATAGAACA

Downstream 100 bases:

>100_bases
TCACGAGTCGCGCAGCAATTGCCAAACGGCCGCCGCAGGCCGTCGCCATTTTTCGGCCTCCGCACGTGCTTGGAACAAAC
TGATAATGATTCCTGTTTGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDGQFLGGDATGSCNTVAALLIHGLGGTEHELRLVEKTLKAEGYETKCAVLPGHGTRPEDLVGVRFEQWLEAVSVEYLEL
RARHDTVHIVGMCMGALLALALSQLIGDRRGRVVALAAPVFLDGWSLPWYRGLRHLVYRLPRARDKFRVKESEPFGVKNG
VLRAAIKARFLRGDTFHYSWTPLTCIRELDRLRSYVRKRVRRVSRPALIIHAREDELTSLRSAYFLSKHIRAAKLLVVDE
SYHMLSIDNDRRLVASTVAQFLREDENSGQNFGTALRGVFAEPANEPFEALVGISLAAE

Sequences:

>Translated_299_residues
MDGQFLGGDATGSCNTVAALLIHGLGGTEHELRLVEKTLKAEGYETKCAVLPGHGTRPEDLVGVRFEQWLEAVSVEYLEL
RARHDTVHIVGMCMGALLALALSQLIGDRRGRVVALAAPVFLDGWSLPWYRGLRHLVYRLPRARDKFRVKESEPFGVKNG
VLRAAIKARFLRGDTFHYSWTPLTCIRELDRLRSYVRKRVRRVSRPALIIHAREDELTSLRSAYFLSKHIRAAKLLVVDE
SYHMLSIDNDRRLVASTVAQFLREDENSGQNFGTALRGVFAEPANEPFEALVGISLAAE
>Mature_299_residues
MDGQFLGGDATGSCNTVAALLIHGLGGTEHELRLVEKTLKAEGYETKCAVLPGHGTRPEDLVGVRFEQWLEAVSVEYLEL
RARHDTVHIVGMCMGALLALALSQLIGDRRGRVVALAAPVFLDGWSLPWYRGLRHLVYRLPRARDKFRVKESEPFGVKNG
VLRAAIKARFLRGDTFHYSWTPLTCIRELDRLRSYVRKRVRRVSRPALIIHAREDELTSLRSAYFLSKHIRAAKLLVVDE
SYHMLSIDNDRRLVASTVAQFLREDENSGQNFGTALRGVFAEPANEPFEALVGISLAAE

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019149
- InterPro:   IPR012354 [H]

Pfam domain/function: PF09752 DUF2048 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 33517; Mature: 33517

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGQFLGGDATGSCNTVAALLIHGLGGTEHELRLVEKTLKAEGYETKCAVLPGHGTRPED
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
LVGVRFEQWLEAVSVEYLELRARHDTVHIVGMCMGALLALALSQLIGDRRGRVVALAAPV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCE
FLDGWSLPWYRGLRHLVYRLPRARDKFRVKESEPFGVKNGVLRAAIKARFLRGDTFHYSW
EECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECC
TPLTCIRELDRLRSYVRKRVRRVSRPALIIHAREDELTSLRSAYFLSKHIRAAKLLVVDE
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEC
SYHMLSIDNDRRLVASTVAQFLREDENSGQNFGTALRGVFAEPANEPFEALVGISLAAE
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDGQFLGGDATGSCNTVAALLIHGLGGTEHELRLVEKTLKAEGYETKCAVLPGHGTRPED
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
LVGVRFEQWLEAVSVEYLELRARHDTVHIVGMCMGALLALALSQLIGDRRGRVVALAAPV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCE
FLDGWSLPWYRGLRHLVYRLPRARDKFRVKESEPFGVKNGVLRAAIKARFLRGDTFHYSW
EECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECC
TPLTCIRELDRLRSYVRKRVRRVSRPALIIHAREDELTSLRSAYFLSKHIRAAKLLVVDE
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEC
SYHMLSIDNDRRLVASTVAQFLREDENSGQNFGTALRGVFAEPANEPFEALVGISLAAE
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]