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The map label for this gene is 73538392

Identifier: 73538392

GI number: 73538392

Start: 1244393

End: 1245559

Strand: Direct

Name: 73538392

Synonym: Reut_B4565

Alternate gene names: NA

Gene position: 1244393-1245559 (Clockwise)

Preceding gene: 73538382

Following gene: 73538393

Centisome position: 45.65

GC content: 65.47

Gene sequence:

>1167_bases
ATGAGCATCAAAGGCAAGGCATATATCGTCGGGGCATACGAACACCCCACCCGCAAGGCACCGGACAAGTCGGTCGCGCA
ACTGCATGCCGAAAGCGCCAAGGGCGCGCTGGAAGACGCGGGCCTTACGCTCGCCGACGTCGACGGCTACTTCTGCGCCG
GCGACGCGCCGGGCCTTGGCGTGCTCAACATGGTCGACTACCTGGGTCTCAAGCTGCGCCATGTCGATTCCACCGAAACG
GGCGGCTCGTCGTACCTGGTGCACGTGGCCCACGCCGCGCAGGCCATTGCCGCAGGCAAGTGCAACGTCGCGCTGATCAC
GCTGGCCGGCCGTCCGCGTTCGGAAGGCTCCAGCGGCACCAAGCCGCGCAACTGGGGCAACAACCTGCCCGACCAGCCGT
TCGAGGCCCCGTTCAGCCCGCTCACGGTCAATTCGTACGCGATGGTCGCCATGCGCCATATGTACGAGTACGGCACCACG
GCCGAACAGCTCGCCTGGATCAAGGTCGCGGCATCGCACCACGCGCAGCACAACCCGAATGCGATGCTGCGCGAGCTCGT
GACCGTTGACGACGTGCTGAACTCGCCGATGATTTCCGATCCGCTGCGCAAGCTCGACTGCTGCGTGGTGTCCGATGGCG
GCGGCGCCCTGATCGTCGCGCGTCCGGAAATCGCGGCAAAGCTGAACCGGCCGAAGGTCAAGGTGCTCGGCGCCGGCGAA
TTCGTGAAGGGGCAGATGGGCGGCCATGTCGACCTTAGCTGGTCGGCCGCGAAGTTCTCGGGCGCGGCAGCATTCGCCGA
AGCCGGGGTGACGCCGGCCGACATCAAATACGCCTCGATCTACGACAGCTTCACGATCACCGTGCTGATGCAGCTTGAGG
ACCTCGGCTTCTGCAAGAAGGGAGACGGCGGCAAGTTCGTGATGGACGGCAACCTGATTTCGGGCGTCGGCAAGCTGCCG
TTCAATACCGATGGCGGTGGGCTGTGCAACAACCACCCGGCCAACCGCGGCGGCATCACCAAGGTGATCGAAGCGGTGCG
CCAGCTGCGTGGCGAGGCACATCCCGCGGTCCAGGTAAAGAACTGCGACCTAGCCGTGGCGCAGGGCATGGGCGGCCTGC
TCGGCTCGCGCCATGGCAGCGCCACGCTGATCCTCGAACGCGAATAA

Upstream 100 bases:

>100_bases
TACATAGCCTGTATTGGAAATTGCACCCCACTTGCCGGAAGATCACGGCGAACGCCGTTTCCAGACGGCCGGCACAACGT
TTCCAACTGAGGGTTCGCGC

Downstream 100 bases:

>100_bases
TCCGCATCCATATCGAATCACCGAGAACGCATCATGAGCACTCCTTTCACCCCGCAAGTCCTGACGGCGCCTGAAGAGCT
GCCGGACAACACCGAGTTCT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAESAKGALEDAGLTLADVDGYFCAGDAPGLGVLNMVDYLGLKLRHVDSTET
GGSSYLVHVAHAAQAIAAGKCNVALITLAGRPRSEGSSGTKPRNWGNNLPDQPFEAPFSPLTVNSYAMVAMRHMYEYGTT
AEQLAWIKVAASHHAQHNPNAMLRELVTVDDVLNSPMISDPLRKLDCCVVSDGGGALIVARPEIAAKLNRPKVKVLGAGE
FVKGQMGGHVDLSWSAAKFSGAAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLAVAQGMGGLLGSRHGSATLILERE

Sequences:

>Translated_388_residues
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAESAKGALEDAGLTLADVDGYFCAGDAPGLGVLNMVDYLGLKLRHVDSTET
GGSSYLVHVAHAAQAIAAGKCNVALITLAGRPRSEGSSGTKPRNWGNNLPDQPFEAPFSPLTVNSYAMVAMRHMYEYGTT
AEQLAWIKVAASHHAQHNPNAMLRELVTVDDVLNSPMISDPLRKLDCCVVSDGGGALIVARPEIAAKLNRPKVKVLGAGE
FVKGQMGGHVDLSWSAAKFSGAAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLAVAQGMGGLLGSRHGSATLILERE
>Mature_387_residues
SIKGKAYIVGAYEHPTRKAPDKSVAQLHAESAKGALEDAGLTLADVDGYFCAGDAPGLGVLNMVDYLGLKLRHVDSTETG
GSSYLVHVAHAAQAIAAGKCNVALITLAGRPRSEGSSGTKPRNWGNNLPDQPFEAPFSPLTVNSYAMVAMRHMYEYGTTA
EQLAWIKVAASHHAQHNPNAMLRELVTVDDVLNSPMISDPLRKLDCCVVSDGGGALIVARPEIAAKLNRPKVKVLGAGEF
VKGQMGGHVDLSWSAAKFSGAAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLPF
NTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLAVAQGMGGLLGSRHGSATLILERE

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=377, Percent_Identity=27.0557029177719, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI302344760, Length=320, Percent_Identity=27.1875, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI302344767, Length=320, Percent_Identity=27.1875, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI302344762, Length=243, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI55956775, Length=205, Percent_Identity=29.2682926829268, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=391, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921506, Length=391, Percent_Identity=26.3427109974425, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24585051, Length=391, Percent_Identity=27.1099744245524, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40773; Mature: 40642

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAESAKGALEDAGLTLADVDGYFCAGDAPGLG
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCEEEEECCCEEECCCCCCCH
VLNMVDYLGLKLRHVDSTETGGSSYLVHVAHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEECCCCCCCCCEEEEEEEHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
KPRNWGNNLPDQPFEAPFSPLTVNSYAMVAMRHMYEYGTTAEQLAWIKVAASHHAQHNPN
CCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCHHHEEEEEEEHHHCCCCCHH
AMLRELVTVDDVLNSPMISDPLRKLDCCVVSDGGGALIVARPEIAAKLNRPKVKVLGAGE
HHHHHHHHHHHHHCCCCHHCHHHHCCEEEEECCCCEEEEECCHHHHHCCCCEEEEEECCC
FVKGQMGGHVDLSWSAAKFSGAAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKK
EEECCCCCEEEEEECHHHCCCHHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCEEC
GDGGKFVMDGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
NCDLAVAQGMGGLLGSRHGSATLILERE
CCCEEECCCCCHHHCCCCCCEEEEEECC
>Mature Secondary Structure 
SIKGKAYIVGAYEHPTRKAPDKSVAQLHAESAKGALEDAGLTLADVDGYFCAGDAPGLG
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCEEEEECCCEEECCCCCCCH
VLNMVDYLGLKLRHVDSTETGGSSYLVHVAHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEECCCCCCCCCEEEEEEEHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
KPRNWGNNLPDQPFEAPFSPLTVNSYAMVAMRHMYEYGTTAEQLAWIKVAASHHAQHNPN
CCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCHHHEEEEEEEHHHCCCCCHH
AMLRELVTVDDVLNSPMISDPLRKLDCCVVSDGGGALIVARPEIAAKLNRPKVKVLGAGE
HHHHHHHHHHHHHCCCCHHCHHHHCCEEEEECCCCEEEEECCHHHHHCCCCEEEEEECCC
FVKGQMGGHVDLSWSAAKFSGAAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKK
EEECCCCCEEEEEECHHHCCCHHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCEEC
GDGGKFVMDGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
NCDLAVAQGMGGLLGSRHGSATLILERE
CCCEEECCCCCHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]