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The map label for this gene is mtaD [H]

Identifier: 73538357

GI number: 73538357

Start: 1202276

End: 1203742

Strand: Reverse

Name: mtaD [H]

Synonym: Reut_B4530

Alternate gene names: 73538357

Gene position: 1203742-1202276 (Counterclockwise)

Preceding gene: 73538358

Following gene: 73538356

Centisome position: 44.16

GC content: 67.35

Gene sequence:

>1467_bases
ATGACACATCGATCCGCATTCCAGCCAGCGTGGCCTGGCGATCTGGCGCCGCCCCTGGACCCGGCACGCCTTGCCGAACC
CCATATCCTCCAGCCCGAATGGACGCTGTTGCGCCACGGTGCCGTGCGCGATCACGCGGTGGTGGTCGAGGGCGGCCGCT
TCACGGCGGTAGGCCCGGTCGACGACGTTGCCGCGCAGTTTCCGTCGCTGAAGCGGCTTTCCCTGCCAGGCATGCTGCTG
ATGCCCGGCATGATCGACACCCATCACCACCTGACCCAGTCGTTCGGCAAGTCGCTGGTGTTCGGCGAGCCCTCAGAGAT
TTTCCGTCGCGTATGGGTCCCGCTGGAAGGCAGTCTCAACGCCGAGCATCTCTACCTGTCGTCAAAACTCGCGGCGCTGG
AGGCGCTGCGCGGCGGCTTCACGACCGTCGTGGATGCGGGCACGCGCAGCGACGCGGGGCTCGACGCCATTGCGCGGGCC
GTGTCCGATGCCGGCGTGCGGTGCGTGCTGGGGCTGATCTGCAACGACCGCCCGGGCGCCGAGACGCTCGATGCCGCTCC
CATCCAGCGCCGCGCATCCGAGCATCTTGGCCGCTACGATCACCACGCACTGGTCACGCCATCGCTGGCGATCTCGATTC
CCGAAGTCGCCAGCGATGCGATGCTGCATTACGTACATCGCATGTGTGCCGAAGCGGGTCGAATTTTCCAGACGCATGCC
AACGAGCACCTGGTCGCGGTGGAGCGTTCGCTCAACGCCTGCGGCCGCCGGCCGATCGAACATCTGGCAGCCGTAGGAGC
GCTTGGCCCCGCGGCGCTGCTGGCGCATGCCACGCTGGTCACGCCGCATGAGATCCGCCTGCTGGCCGACACTGGCGCGG
CCGTTGCCTACAACCCGGTGGCCAGTGCATGGAAGGGCAATGCCGTGGCACCGGCTGAAACCATGGCCACCTTCGGCGTT
CGGCTCGGATTGGGCACCGACGGTACGCGCAGCGACGGCTTCCGTCTGCTCGACTATGCCGAAGCGGCGCAGCGTTTTGC
GTTCGGCATCGGCGTGGGCGACTCATCGTGCGGGGCCGGCTGGCGCTGGCTCGACATGGCGACGCATGATGCTGCCGACG
TGGCCGGTCTTGGTGCGGTGACCGGCGAGATTGCCGCGGGCAAGCGTGCGGATTTCCTGCTGGTCGATCTCGACGTGCCG
GAGCTGACGCCTTCTTGGGACGTGACGTGGGAGCTCGTGCGTCTTGCCAATCGCGACCAGATCCGCGCTGTGTTTGTCGA
TGGCAAGTTACGGCTGTGGGAAGGATGGCCGCCGGACTGGGATGCACGTGCGCTGATGCGTGATATCCGCGCGATGGCCG
CCGACACGATTGCCGGCGCGCCGATCCGCAAACTGCACGACTACGCCGATGCACATCGCGCGCGGCACGCGCAAACGGTG
CCGCACGCCGGCACGCCTGGAGCATGA

Upstream 100 bases:

>100_bases
TCACTGCCGCCTTGCTCAACTTCCTGTTCTTCCACACGGGCGCCAGGCGCGTCGCCGACGTGGCGCCTGTTACGCACTGA
AACCGTATCCGGAAATCCGA

Downstream 100 bases:

>100_bases
CGATGGATCTGACGGTTTTCAGTGTCTGCGCCGCGGTGTTCACCGGTGCGCTGATCCAGGGCGCGACCGGCATGGGTTTT
GCGCTGATCGTCGTGCCGGT

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTHRSAFQPAWPGDLAPPLDPARLAEPHILQPEWTLLRHGAVRDHAVVVEGGRFTAVGPVDDVAAQFPSLKRLSLPGMLL
MPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLEGSLNAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAIARA
VSDAGVRCVLGLICNDRPGAETLDAAPIQRRASEHLGRYDHHALVTPSLAISIPEVASDAMLHYVHRMCAEAGRIFQTHA
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPHEIRLLADTGAAVAYNPVASAWKGNAVAPAETMATFGV
RLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWLDMATHDAADVAGLGAVTGEIAAGKRADFLLVDLDVP
ELTPSWDVTWELVRLANRDQIRAVFVDGKLRLWEGWPPDWDARALMRDIRAMAADTIAGAPIRKLHDYADAHRARHAQTV
PHAGTPGA

Sequences:

>Translated_488_residues
MTHRSAFQPAWPGDLAPPLDPARLAEPHILQPEWTLLRHGAVRDHAVVVEGGRFTAVGPVDDVAAQFPSLKRLSLPGMLL
MPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLEGSLNAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAIARA
VSDAGVRCVLGLICNDRPGAETLDAAPIQRRASEHLGRYDHHALVTPSLAISIPEVASDAMLHYVHRMCAEAGRIFQTHA
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPHEIRLLADTGAAVAYNPVASAWKGNAVAPAETMATFGV
RLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWLDMATHDAADVAGLGAVTGEIAAGKRADFLLVDLDVP
ELTPSWDVTWELVRLANRDQIRAVFVDGKLRLWEGWPPDWDARALMRDIRAMAADTIAGAPIRKLHDYADAHRARHAQTV
PHAGTPGA
>Mature_487_residues
THRSAFQPAWPGDLAPPLDPARLAEPHILQPEWTLLRHGAVRDHAVVVEGGRFTAVGPVDDVAAQFPSLKRLSLPGMLLM
PGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLEGSLNAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAIARAV
SDAGVRCVLGLICNDRPGAETLDAAPIQRRASEHLGRYDHHALVTPSLAISIPEVASDAMLHYVHRMCAEAGRIFQTHAN
EHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPHEIRLLADTGAAVAYNPVASAWKGNAVAPAETMATFGVR
LGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWLDMATHDAADVAGLGAVTGEIAAGKRADFLLVDLDVPE
LTPSWDVTWELVRLANRDQIRAVFVDGKLRLWEGWPPDWDARALMRDIRAMAADTIAGAPIRKLHDYADAHRARHAQTVP
HAGTPGA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=422, Percent_Identity=22.7488151658768, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789249, Length=414, Percent_Identity=22.463768115942, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 52286; Mature: 52155

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRSAFQPAWPGDLAPPLDPARLAEPHILQPEWTLLRHGAVRDHAVVVEGGRFTAVGPV
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHCCCCCCCEEEEECCEEEEECCH
DDVAAQFPSLKRLSLPGMLLMPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLEGSLN
HHHHHHCCCCHHCCCCCCEECCCCCHHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCCC
AEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAIARAVSDAGVRCVLGLICNDRPGA
CCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHEEEHHHCCCCCCC
ETLDAAPIQRRASEHLGRYDHHALVTPSLAISIPEVASDAMLHYVHRMCAEAGRIFQTHA
CCCCCCHHHHHHHHHCCCCCCCEEECCHHEEECHHHHHHHHHHHHHHHHHHHHHEEHHCC
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPHEIRLLADTGAAVAYNPV
CCEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCH
ASAWKGNAVAPAETMATFGVRLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAG
HHHCCCCCCCCHHHHHHHHEEEECCCCCCCCCCEEHHHHHHHHHHHEEEECCCCCCCCCC
WRWLDMATHDAADVAGLGAVTGEIAAGKRADFLLVDLDVPELTPSWDVTWELVRLANRDQ
EEEEECCCCCHHHHHHCCHHHCHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
IRAVFVDGKLRLWEGWPPDWDARALMRDIRAMAADTIAGAPIRKLHDYADAHRARHAQTV
EEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PHAGTPGA
CCCCCCCC
>Mature Secondary Structure 
THRSAFQPAWPGDLAPPLDPARLAEPHILQPEWTLLRHGAVRDHAVVVEGGRFTAVGPV
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHCCCCCCCEEEEECCEEEEECCH
DDVAAQFPSLKRLSLPGMLLMPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLEGSLN
HHHHHHCCCCHHCCCCCCEECCCCCHHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCCC
AEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAIARAVSDAGVRCVLGLICNDRPGA
CCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHEEEHHHCCCCCCC
ETLDAAPIQRRASEHLGRYDHHALVTPSLAISIPEVASDAMLHYVHRMCAEAGRIFQTHA
CCCCCCHHHHHHHHHCCCCCCCEEECCHHEEECHHHHHHHHHHHHHHHHHHHHHEEHHCC
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPHEIRLLADTGAAVAYNPV
CCEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCH
ASAWKGNAVAPAETMATFGVRLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAG
HHHCCCCCCCCHHHHHHHHEEEECCCCCCCCCCEEHHHHHHHHHHHEEEECCCCCCCCCC
WRWLDMATHDAADVAGLGAVTGEIAAGKRADFLLVDLDVPELTPSWDVTWELVRLANRDQ
EEEEECCCCCHHHHHHCCHHHCHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
IRAVFVDGKLRLWEGWPPDWDARALMRDIRAMAADTIAGAPIRKLHDYADAHRARHAQTV
EEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PHAGTPGA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA