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The map label for this gene is 73538339

Identifier: 73538339

GI number: 73538339

Start: 1184546

End: 1185577

Strand: Direct

Name: 73538339

Synonym: Reut_B4512

Alternate gene names: NA

Gene position: 1184546-1185577 (Clockwise)

Preceding gene: 73538338

Following gene: 73538353

Centisome position: 43.45

GC content: 65.41

Gene sequence:

>1032_bases
ATGGATACCGCAAGCGAATTGCAGGCCACGATCCGGGCAATGGTGCAGCCGGGCAAGGGATTGCTCGCCGCCGATGAGAG
CGGCCCGACCATCGCCAAGCGCTTCACCACGATCGGCGTGGAATCGAACGAAGAGAACCGCCGCGCGTGGCGCAGCCTGT
TGCTGTCCACACCAGGGCTTGGCGCGCATATCAGCGGTGTGATCCTGTATGAGGAAACGCTGGGCCAGCGCGCCGACGAC
GGCACGCCGCTGCCCGAGCTTTGCGCGCGCCAGGGCATCGTGCCCGGCATCAAGGTGGACAAGGGAAAGGTTCCACTCGT
GAATGCGCCCGGTGACGAGATCACCGAAGGTCTGGACGGACTGCCAAAGCGACTGGAGGCCTACCGCCAGCAAGGCGCGC
GCTTTGCAAAGTGGCGCGCGGTGTTCAACGTGTCGGACACGCTGCCGAGCGCGCTGGCGGTGCAGGCCAATGCGCAGGTG
CTCGCCGCGTATGCGGCAATCTGCCAGGCGTCAGGCATCGTGCCGATCGTGGAACCCGAGGTGCTGATGGATGGCGATCA
TGGGCTGGCGCGCTCCGCTGCGGTGACGGAGCGCGTGCTCCATGCGGTGTTTCACGCGTTGCATCGCTATGGGGTCGTGC
TCGAACACATGGTGCTCAAGCCGAGCATGGTCATCGCAGGCAAGAAAAGCGCGCAGCAAACATCCGTGCAAGACGTCGCG
ACCGAAACGGTGCGCGTGCTGAAGCGCACGGTCCCCGGCGCGGTACCCGGCATCTTCTTCCTGTCCGGCGGACAGACACC
GGAACAGGCGACAGCAAACCTGGATGCCATGAACCGGCTGGGTCCGCTGCCGTGGCCGCTGAGCTTTTCCTACGGGCGCG
CGCTGCAGGAGCCGCCGCTGGCGGCATGGCGCGGACAGGCCGCAAATGTCGGGAAGGCGCAGCAGGCGCTGCTGCAAAGG
TCGCTTCTGAACGGCGAGGCGTGTCAGGGACAGTACGAGGCAGCGCAGGAATCGATGGAAAAAGTGGGGTAA

Upstream 100 bases:

>100_bases
CCGCAACCTGTCCAAGACGCAGCGCGCCACGTTGCAGCGCGCCAAGGGCAAGCTGCGCGAGGCGTTCGGCCGCACCGCGT
GACCGCAGAGAGGAGAATCC

Downstream 100 bases:

>100_bases
GCCACGGAGGCGGCCAGCGGCTAGGCGTCAGGGCCCCGCCGCTTGCGCCCCGTCACCATGGCCAGCACAAGGTTCTCCTT
GCCCGCCACGCTGAACACGA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDTASELQATIRAMVQPGKGLLAADESGPTIAKRFTTIGVESNEENRRAWRSLLLSTPGLGAHISGVILYEETLGQRADD
GTPLPELCARQGIVPGIKVDKGKVPLVNAPGDEITEGLDGLPKRLEAYRQQGARFAKWRAVFNVSDTLPSALAVQANAQV
LAAYAAICQASGIVPIVEPEVLMDGDHGLARSAAVTERVLHAVFHALHRYGVVLEHMVLKPSMVIAGKKSAQQTSVQDVA
TETVRVLKRTVPGAVPGIFFLSGGQTPEQATANLDAMNRLGPLPWPLSFSYGRALQEPPLAAWRGQAANVGKAQQALLQR
SLLNGEACQGQYEAAQESMEKVG

Sequences:

>Translated_343_residues
MDTASELQATIRAMVQPGKGLLAADESGPTIAKRFTTIGVESNEENRRAWRSLLLSTPGLGAHISGVILYEETLGQRADD
GTPLPELCARQGIVPGIKVDKGKVPLVNAPGDEITEGLDGLPKRLEAYRQQGARFAKWRAVFNVSDTLPSALAVQANAQV
LAAYAAICQASGIVPIVEPEVLMDGDHGLARSAAVTERVLHAVFHALHRYGVVLEHMVLKPSMVIAGKKSAQQTSVQDVA
TETVRVLKRTVPGAVPGIFFLSGGQTPEQATANLDAMNRLGPLPWPLSFSYGRALQEPPLAAWRGQAANVGKAQQALLQR
SLLNGEACQGQYEAAQESMEKVG
>Mature_343_residues
MDTASELQATIRAMVQPGKGLLAADESGPTIAKRFTTIGVESNEENRRAWRSLLLSTPGLGAHISGVILYEETLGQRADD
GTPLPELCARQGIVPGIKVDKGKVPLVNAPGDEITEGLDGLPKRLEAYRQQGARFAKWRAVFNVSDTLPSALAVQANAQV
LAAYAAICQASGIVPIVEPEVLMDGDHGLARSAAVTERVLHAVFHALHRYGVVLEHMVLKPSMVIAGKKSAQQTSVQDVA
TETVRVLKRTVPGAVPGIFFLSGGQTPEQATANLDAMNRLGPLPWPLSFSYGRALQEPPLAAWRGQAANVGKAQQALLQR
SLLNGEACQGQYEAAQESMEKVG

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=330, Percent_Identity=53.030303030303, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI34577110, Length=330, Percent_Identity=53.030303030303, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI4557305, Length=330, Percent_Identity=53.030303030303, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI193794814, Length=330, Percent_Identity=53.030303030303, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI4885063, Length=335, Percent_Identity=51.9402985074627, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI40354205, Length=330, Percent_Identity=49.6969696969697, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI71983985, Length=329, Percent_Identity=53.4954407294833, Blast_Score=337, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI25150450, Length=330, Percent_Identity=50.3030303030303, Blast_Score=329, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI71983990, Length=231, Percent_Identity=53.2467532467532, Blast_Score=242, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24650282, Length=331, Percent_Identity=53.7764350453172, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24650280, Length=331, Percent_Identity=53.7764350453172, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24650278, Length=331, Percent_Identity=53.7764350453172, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI45553577, Length=331, Percent_Identity=53.7764350453172, Blast_Score=344, Evalue=4e-95,
Organism=Drosophila melanogaster, GI221459619, Length=333, Percent_Identity=53.7537537537538, Blast_Score=343, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24650288, Length=333, Percent_Identity=53.7537537537538, Blast_Score=343, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24650304, Length=330, Percent_Identity=45.1515151515152, Blast_Score=291, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36521; Mature: 36521

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTASELQATIRAMVQPGKGLLAADESGPTIAKRFTTIGVESNEENRRAWRSLLLSTPGL
CCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCCCC
GAHISGVILYEETLGQRADDGTPLPELCARQGIVPGIKVDKGKVPLVNAPGDEITEGLDG
CCCCEEEEEEHHHHCCCCCCCCCHHHHHHHCCCCCCCEECCCCCCEEECCCHHHHHHHCC
LPKRLEAYRQQGARFAKWRAVFNVSDTLPSALAVQANAQVLAAYAAICQASGIVPIVEPE
HHHHHHHHHHHCCHHHHHHHEECHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCEEECCC
VLMDGDHGLARSAAVTERVLHAVFHALHRYGVVLEHMVLKPSMVIAGKKSAQQTSVQDVA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
TETVRVLKRTVPGAVPGIFFLSGGQTPEQATANLDAMNRLGPLPWPLSFSYGRALQEPPL
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCC
AAWRGQAANVGKAQQALLQRSLLNGEACQGQYEAAQESMEKVG
HHHCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDTASELQATIRAMVQPGKGLLAADESGPTIAKRFTTIGVESNEENRRAWRSLLLSTPGL
CCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCCCC
GAHISGVILYEETLGQRADDGTPLPELCARQGIVPGIKVDKGKVPLVNAPGDEITEGLDG
CCCCEEEEEEHHHHCCCCCCCCCHHHHHHHCCCCCCCEECCCCCCEEECCCHHHHHHHCC
LPKRLEAYRQQGARFAKWRAVFNVSDTLPSALAVQANAQVLAAYAAICQASGIVPIVEPE
HHHHHHHHHHHCCHHHHHHHEECHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCEEECCC
VLMDGDHGLARSAAVTERVLHAVFHALHRYGVVLEHMVLKPSMVIAGKKSAQQTSVQDVA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
TETVRVLKRTVPGAVPGIFFLSGGQTPEQATANLDAMNRLGPLPWPLSFSYGRALQEPPL
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCC
AAWRGQAANVGKAQQALLQRSLLNGEACQGQYEAAQESMEKVG
HHHCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]