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The map label for this gene is paaG [H]

Identifier: 73538353

GI number: 73538353

Start: 1199183

End: 1199959

Strand: Direct

Name: paaG [H]

Synonym: Reut_B4526

Alternate gene names: 73538353

Gene position: 1199183-1199959 (Clockwise)

Preceding gene: 73538339

Following gene: 73538355

Centisome position: 43.99

GC content: 63.32

Gene sequence:

>777_bases
ATGTCTTCCGAAATCCGCACCGAACTCGACCACGGCATCCAGACGATTACGCTTTCCCGCCCGGACAAGATGAACGCTCT
CACGAACGACATGTACGGCACACTCGCCGATACGATCGAGCGCGCACAGCAGGACCGCAATATCCGGGTATTGCTGCTGC
AGGCTGATGGGGACAGCTTCACGGCGGGCAACGATTTGGGCGAGTTCGCGGCGATTGCTGCCGGCAAGGGCCCGAGCGAA
CGTCATGTCCATCGCTTTCTGCGCGCCCTGGCCAATTCGACCGTGCCGGTCGTGGTCGCGGTGCACGGCAATGCCGTGGG
CGTGGGCACCACCATGCTGCTGCATTGCGACTACGTCGTGCTTGGCGAAGATGCCAGACTGGTCACGCCGTTCGTCAACC
TCGCGCTGGTTCCCGAAGCGGCTTCGAGCTACCTGCTGCCGCTGCGCATCGGCCACGCACGGGCGTTCCAGATGTTCGCG
CTGGGCGAGTCGCTTGATGCGCAAACCGCCGTGGCATGGGGCATTGCCAACAAGGTCAGCGCCAGCGGCGAGTTGCGTGC
AGACGCGCGGCGAATGGCCGAGAAGCTTGCCAGCAAACCCGCCGGTTCACTGAGCGCCATGAAGACACTCATGCGCGACG
CAGAAAAACTGGTCGCGCAGATGACCAGCGAAAGCGCCCAATTCGAAGCACGGCTGGCCAGCGCCGAAGCGCGCGAGGCA
TTCTCCGCGTTCGCCGAGAAGCGCAAGCCGGACTTCGTCAAGATCGCCCAGCAATAA

Upstream 100 bases:

>100_bases
CCGAGCCCCGGTTTACTTCGCACGCGAATTATCTATATACTTCGCACACGAAATTAATCTTGACGCCGCCTGGCACCGCA
CATCCCCTTGGAGAACAACC

Downstream 100 bases:

>100_bases
GTCCCAGTGAACTGACTAGACCTCGCCCTCGTCAGTAGCGGGGAACTTCGTCTGCAGGCTGGTGAGCCACCTTGCCACCA
CGTCGATCTCCGCTTCACTG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSSEIRTELDHGIQTITLSRPDKMNALTNDMYGTLADTIERAQQDRNIRVLLLQADGDSFTAGNDLGEFAAIAAGKGPSE
RHVHRFLRALANSTVPVVVAVHGNAVGVGTTMLLHCDYVVLGEDARLVTPFVNLALVPEAASSYLLPLRIGHARAFQMFA
LGESLDAQTAVAWGIANKVSASGELRADARRMAEKLASKPAGSLSAMKTLMRDAEKLVAQMTSESAQFEARLASAEAREA
FSAFAEKRKPDFVKIAQQ

Sequences:

>Translated_258_residues
MSSEIRTELDHGIQTITLSRPDKMNALTNDMYGTLADTIERAQQDRNIRVLLLQADGDSFTAGNDLGEFAAIAAGKGPSE
RHVHRFLRALANSTVPVVVAVHGNAVGVGTTMLLHCDYVVLGEDARLVTPFVNLALVPEAASSYLLPLRIGHARAFQMFA
LGESLDAQTAVAWGIANKVSASGELRADARRMAEKLASKPAGSLSAMKTLMRDAEKLVAQMTSESAQFEARLASAEAREA
FSAFAEKRKPDFVKIAQQ
>Mature_257_residues
SSEIRTELDHGIQTITLSRPDKMNALTNDMYGTLADTIERAQQDRNIRVLLLQADGDSFTAGNDLGEFAAIAAGKGPSER
HVHRFLRALANSTVPVVVAVHGNAVGVGTTMLLHCDYVVLGEDARLVTPFVNLALVPEAASSYLLPLRIGHARAFQMFAL
GESLDAQTAVAWGIANKVSASGELRADARRMAEKLASKPAGSLSAMKTLMRDAEKLVAQMTSESAQFEARLASAEAREAF
SAFAEKRKPDFVKIAQQ

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=247, Percent_Identity=29.1497975708502, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI260275230, Length=247, Percent_Identity=29.1497975708502, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI260274832, Length=247, Percent_Identity=29.1497975708502, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=29.2, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=26.2096774193548, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4757968, Length=257, Percent_Identity=26.8482490272374, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI49355787, Length=257, Percent_Identity=26.8482490272374, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI25453481, Length=257, Percent_Identity=26.4591439688716, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI51538573, Length=257, Percent_Identity=26.4591439688716, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4757966, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI51538581, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI116235487, Length=209, Percent_Identity=29.6650717703349, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221307494, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI221136756, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI221136753, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4502327, Length=274, Percent_Identity=25.9124087591241, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI68989263, Length=218, Percent_Identity=27.5229357798165, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI70995211, Length=186, Percent_Identity=24.7311827956989, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=33.8461538461538, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=31.8897637795276, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788597, Length=266, Percent_Identity=25.9398496240602, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790281, Length=190, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788682, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082183, Length=255, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=242, Percent_Identity=32.6446280991736, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=28.1124497991968, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=29.7674418604651, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=255, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=23.5521235521236, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323314, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24654903, Length=236, Percent_Identity=27.5423728813559, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=29.1338582677165, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=21.9123505976096, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27753; Mature: 27622

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEIRTELDHGIQTITLSRPDKMNALTNDMYGTLADTIERAQQDRNIRVLLLQADGDSF
CCCHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
TAGNDLGEFAAIAAGKGPSERHVHRFLRALANSTVPVVVAVHGNAVGVGTTMLLHCDYVV
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEECHHHEEEEEECEEE
LGEDARLVTPFVNLALVPEAASSYLLPLRIGHARAFQMFALGESLDAQTAVAWGIANKVS
ECCCCEEEHHHHHHEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ASGELRADARRMAEKLASKPAGSLSAMKTLMRDAEKLVAQMTSESAQFEARLASAEAREA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAFAEKRKPDFVKIAQQ
HHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
SSEIRTELDHGIQTITLSRPDKMNALTNDMYGTLADTIERAQQDRNIRVLLLQADGDSF
CCHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
TAGNDLGEFAAIAAGKGPSERHVHRFLRALANSTVPVVVAVHGNAVGVGTTMLLHCDYVV
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEECHHHEEEEEECEEE
LGEDARLVTPFVNLALVPEAASSYLLPLRIGHARAFQMFALGESLDAQTAVAWGIANKVS
ECCCCEEEHHHHHHEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ASGELRADARRMAEKLASKPAGSLSAMKTLMRDAEKLVAQMTSESAQFEARLASAEAREA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAFAEKRKPDFVKIAQQ
HHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]