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The map label for this gene is bvgS [H]

Identifier: 73538298

GI number: 73538298

Start: 1136687

End: 1138723

Strand: Reverse

Name: bvgS [H]

Synonym: Reut_B4471

Alternate gene names: 73538298

Gene position: 1138723-1136687 (Counterclockwise)

Preceding gene: 73538300

Following gene: 73538297

Centisome position: 41.77

GC content: 67.94

Gene sequence:

>2037_bases
ATGCTGACCGCGCCAACCCCGATCACTGGCCTGCTGGCCGCCTGCGTGGTGCTCATGGCCGCCTGCCTGCTGCACTGGCA
CCGGCGTCTGCGAACGATGGGCAGCCAACGCGATGTGCTGGCCGCCATCATTGACGCTGCGCCATATCCGATGGTGGCGC
GCGACGCACGCGGGCGCTTCGTCGCAGTCAATGTGGCGCTTGAGGATTTTCTCGACATCCGCCGCCAGACAATGCTGGGG
AAGACCATGGAAGACGCTGGCGTGCCGCCCAACATCGTGGCTGCCGTGGCATCGCCGATCGCGCGCGCGCGGGCGTCAGG
CCAGCGGGTCGACGAGACGCTGCGCGTGCGTGATGCCGCCGGCGAGTGGCATGACCTGCTCTTCGCCACGCAGCCGCTGC
GCCTGCCGGACGGCACCGAGGCAGGCACCGTTTCCGCGACCATCGACATCACCGCCCAGCTCGCAGCCGAACAGGCCGCC
CTCGAGGCCAAGCGCGTGCTCGATGAGATTGCCGACGCCTTGCCCGTGGCGTCGTTCCAGCTCTGCGCGGAGCCGGGTGG
CCGGTACTGGTTTTCGTATTTTTCCGCGAAGGCGGAACGGTATCGCGGCTGGTCCGCCGAACGGCTGCTCGCCGTGGTCG
ATGGCGAATACCCGTCGATCCATCCGGAGGACCGCTTGAAAATGGCCGACGCGTTGCATCAGTCCGCTGCCGCGCAATCG
GCCGCGCAGTTTGAACTCCGGATTCTTGTCGACGGCGAAACGCGGTGGCTGCGCTTGTTCGTGGGCGCACCGGCGCGTGA
TCCATCCGGCCAGTTGCGCTGGAGCGGTTATGCCGGCGACGCGACCGACGAACATCGCCAGCTCGAAGCGCTGGCGGCGG
CCCGCGCGGCCGCGGAAGGCGCCGCACAGGCGAAGGCGCGCTTCCTGGCCACGATGACGCACGAGATCCGCACGCCGCTG
GCAGCGGTCATCGGTGCGCTGGAACTGTTGCGCGGCAGCCCGATGAGCGCGCAGCAGGCCAGCGAGGTCGCGCTGGCCGA
CAATGCGGCGCGCCTGCTCATGGAAATCCTCGACGGCATCCTCGACTACAGTCGCCTGGAGGCCGGGCAACTCGCGTTGG
AGTCGCTGCCGCTGGATCTGCGCGCCCTCGTCGAGTCGGTGATGCAGGTGCACAGGCCCGCGGTCGCGGCAAAGCAGCTC
GCGTTTGCGTTCGAAGCCGATGCGCGCGTTGCCGTGGCCTTGCTAGGCGATCCCACGCGGCTCAAGGAGATCCTGCTCAA
CCTGATCGGCAATGCTGTGAAGTTTACGGCGCAGGGCGGCATTACGGTGCGATTGGACTTGCTCGAAGACATGGAGGAGC
ACCAGCGTGTGTCGCTCAGCGTCGCCGATACCGGCGTGGGTATCGACGCCAGACAGCAAGAGCAGCTGTTCGCGCCATTT
TCGCAGGCAGATAGCTCCATTTCGCGCCGTTTTGGCGGCAGCGGGCTGGGCCTGGCGATCTGCCGGCGCCTGGCGGAACG
GATGGGCGGCACGCTGACGCTGCAAAGCCAGCCTGGGGCCGGCACTACGATTGTGCTGTGTGTGACGTTGCCAGTGGCCA
TGAGCCCAGTGCCCCAAGGGGTCGCCGGCCGCGCTGGGCCGCCGCCCCCCTTGGAACCGCTGGACGTGCGCAAGGCCATC
CTGGTAGTGGAAGACCACCTGCCGTTCCAGGTCATCATGCGCCGGCAACTGGAGATGCTGGGGCAGGATTGCACGGTGGC
GTCCGGGGGCGAAGCGGCGCTGGAGCAGCTCCGGCAGCAGCGTTTCGCGCTGGTACTGACCGATTGCCAGATGCCCGGCA
TGAACGGTTTCGAACTGGCCAGCCGCATCCGGGCATCCGGGCCGGGCGCCAATGCCGACGTGCCGATCGTCGCGCTGACG
GCGTCTGCCGGTGCGGAAGTGGCCCGGCAATGCCACGACGCGGGCATGGACGCCTGTCTCGCCAAGCCCGTTCGCATGGA
CGACCTGCGCGCATGCATTGCCCGATGGGCGCGGTAA

Upstream 100 bases:

>100_bases
GTCGTCGCGGCCACCGGGCCGAGCGGCTGGCAAGCCACCGGGCAACGCTATCATTGTCTTGCCCTGCTCGTCTGTTACCT
GTCCGCGATGGAGTTTTCCG

Downstream 100 bases:

>100_bases
GGCGCATCATGAGGTGACTGTCCGGCGCCGTTGCAGTGCGCAGGCGATGCCGGTGGGTGCAGGATCCTGCTCGTGAAGGT
CAATCGGGAAAAGTCGTACC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MLTAPTPITGLLAACVVLMAACLLHWHRRLRTMGSQRDVLAAIIDAAPYPMVARDARGRFVAVNVALEDFLDIRRQTMLG
KTMEDAGVPPNIVAAVASPIARARASGQRVDETLRVRDAAGEWHDLLFATQPLRLPDGTEAGTVSATIDITAQLAAEQAA
LEAKRVLDEIADALPVASFQLCAEPGGRYWFSYFSAKAERYRGWSAERLLAVVDGEYPSIHPEDRLKMADALHQSAAAQS
AAQFELRILVDGETRWLRLFVGAPARDPSGQLRWSGYAGDATDEHRQLEALAAARAAAEGAAQAKARFLATMTHEIRTPL
AAVIGALELLRGSPMSAQQASEVALADNAARLLMEILDGILDYSRLEAGQLALESLPLDLRALVESVMQVHRPAVAAKQL
AFAFEADARVAVALLGDPTRLKEILLNLIGNAVKFTAQGGITVRLDLLEDMEEHQRVSLSVADTGVGIDARQQEQLFAPF
SQADSSISRRFGGSGLGLAICRRLAERMGGTLTLQSQPGAGTTIVLCVTLPVAMSPVPQGVAGRAGPPPPLEPLDVRKAI
LVVEDHLPFQVIMRRQLEMLGQDCTVASGGEAALEQLRQQRFALVLTDCQMPGMNGFELASRIRASGPGANADVPIVALT
ASAGAEVARQCHDAGMDACLAKPVRMDDLRACIARWAR

Sequences:

>Translated_678_residues
MLTAPTPITGLLAACVVLMAACLLHWHRRLRTMGSQRDVLAAIIDAAPYPMVARDARGRFVAVNVALEDFLDIRRQTMLG
KTMEDAGVPPNIVAAVASPIARARASGQRVDETLRVRDAAGEWHDLLFATQPLRLPDGTEAGTVSATIDITAQLAAEQAA
LEAKRVLDEIADALPVASFQLCAEPGGRYWFSYFSAKAERYRGWSAERLLAVVDGEYPSIHPEDRLKMADALHQSAAAQS
AAQFELRILVDGETRWLRLFVGAPARDPSGQLRWSGYAGDATDEHRQLEALAAARAAAEGAAQAKARFLATMTHEIRTPL
AAVIGALELLRGSPMSAQQASEVALADNAARLLMEILDGILDYSRLEAGQLALESLPLDLRALVESVMQVHRPAVAAKQL
AFAFEADARVAVALLGDPTRLKEILLNLIGNAVKFTAQGGITVRLDLLEDMEEHQRVSLSVADTGVGIDARQQEQLFAPF
SQADSSISRRFGGSGLGLAICRRLAERMGGTLTLQSQPGAGTTIVLCVTLPVAMSPVPQGVAGRAGPPPPLEPLDVRKAI
LVVEDHLPFQVIMRRQLEMLGQDCTVASGGEAALEQLRQQRFALVLTDCQMPGMNGFELASRIRASGPGANADVPIVALT
ASAGAEVARQCHDAGMDACLAKPVRMDDLRACIARWAR
>Mature_678_residues
MLTAPTPITGLLAACVVLMAACLLHWHRRLRTMGSQRDVLAAIIDAAPYPMVARDARGRFVAVNVALEDFLDIRRQTMLG
KTMEDAGVPPNIVAAVASPIARARASGQRVDETLRVRDAAGEWHDLLFATQPLRLPDGTEAGTVSATIDITAQLAAEQAA
LEAKRVLDEIADALPVASFQLCAEPGGRYWFSYFSAKAERYRGWSAERLLAVVDGEYPSIHPEDRLKMADALHQSAAAQS
AAQFELRILVDGETRWLRLFVGAPARDPSGQLRWSGYAGDATDEHRQLEALAAARAAAEGAAQAKARFLATMTHEIRTPL
AAVIGALELLRGSPMSAQQASEVALADNAARLLMEILDGILDYSRLEAGQLALESLPLDLRALVESVMQVHRPAVAAKQL
AFAFEADARVAVALLGDPTRLKEILLNLIGNAVKFTAQGGITVRLDLLEDMEEHQRVSLSVADTGVGIDARQQEQLFAPF
SQADSSISRRFGGSGLGLAICRRLAERMGGTLTLQSQPGAGTTIVLCVTLPVAMSPVPQGVAGRAGPPPPLEPLDVRKAI
LVVEDHLPFQVIMRRQLEMLGQDCTVASGGEAALEQLRQQRFALVLTDCQMPGMNGFELASRIRASGPGANADVPIVALT
ASAGAEVARQCHDAGMDACLAKPVRMDDLRACIARWAR

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=397, Percent_Identity=34.7607052896725, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI48994928, Length=402, Percent_Identity=32.089552238806, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=37.4517374517375, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=37.4531835205993, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081816, Length=397, Percent_Identity=33.7531486146096, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=32.4675324675325, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=29.535864978903, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786600, Length=256, Percent_Identity=29.296875, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=31.4741035856574, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788549, Length=304, Percent_Identity=27.9605263157895, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=29.4605809128631, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=26.271186440678, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=28.8135593220339, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=223, Percent_Identity=31.390134529148, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788545, Length=355, Percent_Identity=23.0985915492958, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=231, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=27.2357723577236, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=30.2222222222222, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=76, Percent_Identity=50, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72621; Mature: 72621

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAPTPITGLLAACVVLMAACLLHWHRRLRTMGSQRDVLAAIIDAAPYPMVARDARGRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCE
VAVNVALEDFLDIRRQTMLGKTMEDAGVPPNIVAAVASPIARARASGQRVDETLRVRDAA
EEEEHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
GEWHDLLFATQPLRLPDGTEAGTVSATIDITAQLAAEQAALEAKRVLDEIADALPVASFQ
CHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LCAEPGGRYWFSYFSAKAERYRGWSAERLLAVVDGEYPSIHPEDRLKMADALHQSAAAQS
HHCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
AAQFELRILVDGETRWLRLFVGAPARDPSGQLRWSGYAGDATDEHRQLEALAAARAAAEG
HCEEEEEEEEECCCEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
AAQAKARFLATMTHEIRTPLAAVIGALELLRGSPMSAQQASEVALADNAARLLMEILDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDYSRLEAGQLALESLPLDLRALVESVMQVHRPAVAAKQLAFAFEADARVAVALLGDPTR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHH
LKEILLNLIGNAVKFTAQGGITVRLDLLEDMEEHQRVSLSVADTGVGIDARQQEQLFAPF
HHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCH
SQADSSISRRFGGSGLGLAICRRLAERMGGTLTLQSQPGAGTTIVLCVTLPVAMSPVPQG
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEHHHHCCCCCCC
VAGRAGPPPPLEPLDVRKAILVVEDHLPFQVIMRRQLEMLGQDCTVASGGEAALEQLRQQ
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RFALVLTDCQMPGMNGFELASRIRASGPGANADVPIVALTASAGAEVARQCHDAGMDACL
HHEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHH
AKPVRMDDLRACIARWAR
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLTAPTPITGLLAACVVLMAACLLHWHRRLRTMGSQRDVLAAIIDAAPYPMVARDARGRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCE
VAVNVALEDFLDIRRQTMLGKTMEDAGVPPNIVAAVASPIARARASGQRVDETLRVRDAA
EEEEHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
GEWHDLLFATQPLRLPDGTEAGTVSATIDITAQLAAEQAALEAKRVLDEIADALPVASFQ
CHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LCAEPGGRYWFSYFSAKAERYRGWSAERLLAVVDGEYPSIHPEDRLKMADALHQSAAAQS
HHCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
AAQFELRILVDGETRWLRLFVGAPARDPSGQLRWSGYAGDATDEHRQLEALAAARAAAEG
HCEEEEEEEEECCCEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
AAQAKARFLATMTHEIRTPLAAVIGALELLRGSPMSAQQASEVALADNAARLLMEILDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDYSRLEAGQLALESLPLDLRALVESVMQVHRPAVAAKQLAFAFEADARVAVALLGDPTR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHH
LKEILLNLIGNAVKFTAQGGITVRLDLLEDMEEHQRVSLSVADTGVGIDARQQEQLFAPF
HHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCH
SQADSSISRRFGGSGLGLAICRRLAERMGGTLTLQSQPGAGTTIVLCVTLPVAMSPVPQG
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEHHHHCCCCCCC
VAGRAGPPPPLEPLDVRKAILVVEDHLPFQVIMRRQLEMLGQDCTVASGGEAALEQLRQQ
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RFALVLTDCQMPGMNGFELASRIRASGPGANADVPIVALTASAGAEVARQCHDAGMDACL
HHEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHH
AKPVRMDDLRACIARWAR
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]