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The map label for this gene is fliD [H]

Identifier: 73538283

GI number: 73538283

Start: 1119244

End: 1120710

Strand: Reverse

Name: fliD [H]

Synonym: Reut_B4456

Alternate gene names: 73538283

Gene position: 1120710-1119244 (Counterclockwise)

Preceding gene: 73538285

Following gene: 73538281

Centisome position: 41.11

GC content: 63.26

Gene sequence:

>1467_bases
ATGACAACCATATCGAATCTGGGCGTCGGCTCAGGTCTCGACCTGAGTTCCCTGCTGGATCAGCTAACGCAGTCTGAACA
GGCGCCGCTGCAAGCGATCCAGGATCAGGAAACCAGCTACCAGACCAAGCTGTCGGCCTACGGACAGCTCAAGAACGCGC
TGACCGCCTTCCAGTCGGCCGCAGGCAAGCTCGGCCAGCCTGACTTCTTCAACGCGACCAAGATCTCCTCGAGCAGTACC
GACGTGCTCAGCGCCACCAGTACCACCGGCGCCGCGCAGGGCACGTACTCGGTCAACGTCACCGCGCTGGCGCAGGCCCA
GTCGCTCGTCGGTGCCGGGCAGGCCAAGGAGGACGCGACGATCGGCACAGGCACGATCCATATCGACTTCGGCACCATCA
GCGGTGGCACGCTGGATACCGACAGCACCAGCGCCACATACGGCAAGTACACGGGCGCCACGTTTGCGGCCAAGGACGGC
AGCACTGGTGTCGATATCAATATCGACAGCACCCATGGCACGCTCGAAGGCGTGCGCGATGCGATCAATGCGGCCAATGC
CGGTGTGACCGCGACCATCCTGAACGACGGATCGGGGTCGCCGTACCGCCTGGTGCTGACGTCCAACGACACGGGCGAGG
CTAACAGCATGCGCATTTCCGTGACCGGCGACAGCACGGGCGCGCTCACCGGCCTGGTGGCCAATGATCCGGCGGGCACC
CAGAACATGGAGCAGACCGTCGCTGCGCGCGATGCCCGGCTCTCTGTCAACAACATCGACATCCAGAGCGCCAGCAACGA
CGTCTCGGCCATTCAGGGCCTGAGCCTGTCGCTGTCGCAGACCGGCACGTCGGTCGTCAGCGTGCAGCGCGACAACACGG
CCATCCAGAACGGCATCCAGGCCTTCGTCACGGCCTACAACAGCCTGCAAAGCACGGCCACGAGCCTGTCGGCCTTCAAC
CCGACCGCGGCGCAGGGCCAGCAGGCCGCCCCGCTGACAGGTGACGGTGTGCTGCGCAACATCCAGACGCAACTCCGCTC
AGCGCTCAATATGCCGGAGGCCGGCGGCCAGGACGCCTTCACGATGCTGTCCCAGGTCGGTGTCAGCTTCCAGAACGACG
GCACGCTGACTTTGGACGCCAACAAGCTGTCCAAGGCCATGAACAGCAATATGGCCGGGGTGGAGACACTGTTCAGCAAC
AGCGACGGCAAGACCGGCTACGGCAACCAGATCAGCAGCCTGGTCGGTGAAATGACCGGAACCGACGGCGAGCTGACTTC
CGCGACCGATGGCATCAACAGCACGCTGAAGGACCTGAGCTCGCAGTACGACTCGACGCAGAACATGGTCAACGACACGA
TCGCAAACTATCGCCAGCAGTTCACCCAGCTGGACACGATCATGGCGCAGATGAAGAACACCAGCACTTACCTGACGCAG
CAGTTCAGTGCGTCGAGCAAGAGCTGA

Upstream 100 bases:

>100_bases
TTGAAGAGAGTTGGTCGAAATGCCCACTGCTATGGTGGCTCGCGGCCAATGTCTGGACATTGCAGCCGCACCTATCCAAG
CAACCGTTGCAGGAATACGC

Downstream 100 bases:

>100_bases
CAGGAAGACTACGAAGAGGATCTTCGGGGTCTTCGCGGGCCGGGGTTTGACTCGGCCCGCGCCTCGGTCAGGCGCCCAGC
GCGTCCGGGTCGATGCCGAG

Product: flagellar hook-associated protein 2

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTTISNLGVGSGLDLSSLLDQLTQSEQAPLQAIQDQETSYQTKLSAYGQLKNALTAFQSAAGKLGQPDFFNATKISSSST
DVLSATSTTGAAQGTYSVNVTALAQAQSLVGAGQAKEDATIGTGTIHIDFGTISGGTLDTDSTSATYGKYTGATFAAKDG
STGVDINIDSTHGTLEGVRDAINAANAGVTATILNDGSGSPYRLVLTSNDTGEANSMRISVTGDSTGALTGLVANDPAGT
QNMEQTVAARDARLSVNNIDIQSASNDVSAIQGLSLSLSQTGTSVVSVQRDNTAIQNGIQAFVTAYNSLQSTATSLSAFN
PTAAQGQQAAPLTGDGVLRNIQTQLRSALNMPEAGGQDAFTMLSQVGVSFQNDGTLTLDANKLSKAMNSNMAGVETLFSN
SDGKTGYGNQISSLVGEMTGTDGELTSATDGINSTLKDLSSQYDSTQNMVNDTIANYRQQFTQLDTIMAQMKNTSTYLTQ
QFSASSKS

Sequences:

>Translated_488_residues
MTTISNLGVGSGLDLSSLLDQLTQSEQAPLQAIQDQETSYQTKLSAYGQLKNALTAFQSAAGKLGQPDFFNATKISSSST
DVLSATSTTGAAQGTYSVNVTALAQAQSLVGAGQAKEDATIGTGTIHIDFGTISGGTLDTDSTSATYGKYTGATFAAKDG
STGVDINIDSTHGTLEGVRDAINAANAGVTATILNDGSGSPYRLVLTSNDTGEANSMRISVTGDSTGALTGLVANDPAGT
QNMEQTVAARDARLSVNNIDIQSASNDVSAIQGLSLSLSQTGTSVVSVQRDNTAIQNGIQAFVTAYNSLQSTATSLSAFN
PTAAQGQQAAPLTGDGVLRNIQTQLRSALNMPEAGGQDAFTMLSQVGVSFQNDGTLTLDANKLSKAMNSNMAGVETLFSN
SDGKTGYGNQISSLVGEMTGTDGELTSATDGINSTLKDLSSQYDSTQNMVNDTIANYRQQFTQLDTIMAQMKNTSTYLTQ
QFSASSKS
>Mature_487_residues
TTISNLGVGSGLDLSSLLDQLTQSEQAPLQAIQDQETSYQTKLSAYGQLKNALTAFQSAAGKLGQPDFFNATKISSSSTD
VLSATSTTGAAQGTYSVNVTALAQAQSLVGAGQAKEDATIGTGTIHIDFGTISGGTLDTDSTSATYGKYTGATFAAKDGS
TGVDINIDSTHGTLEGVRDAINAANAGVTATILNDGSGSPYRLVLTSNDTGEANSMRISVTGDSTGALTGLVANDPAGTQ
NMEQTVAARDARLSVNNIDIQSASNDVSAIQGLSLSLSQTGTSVVSVQRDNTAIQNGIQAFVTAYNSLQSTATSLSAFNP
TAAQGQQAAPLTGDGVLRNIQTQLRSALNMPEAGGQDAFTMLSQVGVSFQNDGTLTLDANKLSKAMNSNMAGVETLFSNS
DGKTGYGNQISSLVGEMTGTDGELTSATDGINSTLKDLSSQYDSTQNMVNDTIANYRQQFTQLDTIMAQMKNTSTYLTQQ
FSASSKS

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=497, Percent_Identity=39.0342052313883, Blast_Score=262, Evalue=4e-71,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 50245; Mature: 50114

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTISNLGVGSGLDLSSLLDQLTQSEQAPLQAIQDQETSYQTKLSAYGQLKNALTAFQSA
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGKLGQPDFFNATKISSSSTDVLSATSTTGAAQGTYSVNVTALAQAQSLVGAGQAKEDAT
HCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCE
IGTGTIHIDFGTISGGTLDTDSTSATYGKYTGATFAAKDGSTGVDINIDSTHGTLEGVRD
ECCEEEEEEEECCCCCEECCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHH
AINAANAGVTATILNDGSGSPYRLVLTSNDTGEANSMRISVTGDSTGALTGLVANDPAGT
HHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCC
QNMEQTVAARDARLSVNNIDIQSASNDVSAIQGLSLSLSQTGTSVVSVQRDNTAIQNGIQ
CHHHHHHHHHHCEEEECCEEECCCCCCHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHH
AFVTAYNSLQSTATSLSAFNPTAAQGQQAAPLTGDGVLRNIQTQLRSALNMPEAGGQDAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
TMLSQVGVSFQNDGTLTLDANKLSKAMNSNMAGVETLFSNSDGKTGYGNQISSLVGEMTG
HHHHHHCCEECCCCEEEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCC
TDGELTSATDGINSTLKDLSSQYDSTQNMVNDTIANYRQQFTQLDTIMAQMKNTSTYLTQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QFSASSKS
HHCCCCCC
>Mature Secondary Structure 
TTISNLGVGSGLDLSSLLDQLTQSEQAPLQAIQDQETSYQTKLSAYGQLKNALTAFQSA
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGKLGQPDFFNATKISSSSTDVLSATSTTGAAQGTYSVNVTALAQAQSLVGAGQAKEDAT
HCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCE
IGTGTIHIDFGTISGGTLDTDSTSATYGKYTGATFAAKDGSTGVDINIDSTHGTLEGVRD
ECCEEEEEEEECCCCCEECCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHH
AINAANAGVTATILNDGSGSPYRLVLTSNDTGEANSMRISVTGDSTGALTGLVANDPAGT
HHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCC
QNMEQTVAARDARLSVNNIDIQSASNDVSAIQGLSLSLSQTGTSVVSVQRDNTAIQNGIQ
CHHHHHHHHHHCEEEECCEEECCCCCCHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHH
AFVTAYNSLQSTATSLSAFNPTAAQGQQAAPLTGDGVLRNIQTQLRSALNMPEAGGQDAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
TMLSQVGVSFQNDGTLTLDANKLSKAMNSNMAGVETLFSNSDGKTGYGNQISSLVGEMTG
HHHHHHCCEECCCCEEEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCC
TDGELTSATDGINSTLKDLSSQYDSTQNMVNDTIANYRQQFTQLDTIMAQMKNTSTYLTQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QFSASSKS
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2193164; 11677609; 1527488; 9878359; 11118149 [H]