Click here to switch to the map view.

The map label for this gene is nhaA2 [H]

Identifier: 73538274

GI number: 73538274

Start: 1108625

End: 1109146

Strand: Direct

Name: nhaA2 [H]

Synonym: Reut_B4447

Alternate gene names: 73538274

Gene position: 1108625-1109146 (Clockwise)

Preceding gene: 73538273

Following gene: 73538280

Centisome position: 40.67

GC content: 63.03

Gene sequence:

>522_bases
ATGCCAGACGTCGCCGTTACCGCTGCCGACCATGCCATCGGCCCTGACACCGCCAGGGTCACCGTCGTCGAATATGGCGA
CTTCGAATGCGAATACTGCCGCATGGCCTACGGCGCCATGAAGATCCTGATGGAGCACTATGGCCCGCAGGTCCGCTTCG
TCTATCGGCACTATCCGATGTCTCACTGGCATCCATCCGCCGAAGCCGCGGCCGAATGCGCGGAAGCGGCCGGCGCGCAG
CAGAAGTTCTGGCAGATGTACCGCCTGCTGCACGAAAAGCCGAACGGCCTGAAATCGGAAGCGCTACGCCACTATGCCGG
CATGCTCGGCATGGACCTGAACCGCTTCGACAGCGACATGGCGGCTCACTCGCACCTGCCGCATATCCGCGATGACATGC
GCGGCGCCACGCAATGGCAGGTACGGGGCACGCCATCGTTCTTCGTCAATGGCGTGGTGCAGGACGTGACCTTCGGTATG
GAACGGCTGCAGCGCGCCATTGATGTGGCGTTGGCGGGTTGA

Upstream 100 bases:

>100_bases
GGGCGCGAAGCTGTAGCCGATCAGCTGGCGGCGCGGTGAGGCCGGTCTGCGCCTAAACTGGAAAGTCCCCGGGCCGCCCG
CCCATGAACCGGAGCGCTCC

Downstream 100 bases:

>100_bases
ACGTTGGTTTCACGAAGAAACCACGACTGCCCTGTCGCGTTGCCCGCCCATGAACATGGCGAGGCCGAATAACTGCAGCG
CTGCCATACAAACCGCCAGC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPDVAVTAADHAIGPDTARVTVVEYGDFECEYCRMAYGAMKILMEHYGPQVRFVYRHYPMSHWHPSAEAAAECAEAAGAQ
QKFWQMYRLLHEKPNGLKSEALRHYAGMLGMDLNRFDSDMAAHSHLPHIRDDMRGATQWQVRGTPSFFVNGVVQDVTFGM
ERLQRAIDVALAG

Sequences:

>Translated_173_residues
MPDVAVTAADHAIGPDTARVTVVEYGDFECEYCRMAYGAMKILMEHYGPQVRFVYRHYPMSHWHPSAEAAAECAEAAGAQ
QKFWQMYRLLHEKPNGLKSEALRHYAGMLGMDLNRFDSDMAAHSHLPHIRDDMRGATQWQVRGTPSFFVNGVVQDVTFGM
ERLQRAIDVALAG
>Mature_172_residues
PDVAVTAADHAIGPDTARVTVVEYGDFECEYCRMAYGAMKILMEHYGPQVRFVYRHYPMSHWHPSAEAAAECAEAAGAQQ
KFWQMYRLLHEKPNGLKSEALRHYAGMLGMDLNRFDSDMAAHSHLPHIRDDMRGATQWQVRGTPSFFVNGVVQDVTFGME
RLQRAIDVALAG

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 19503; Mature: 19372

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVAVTAADHAIGPDTARVTVVEYGDFECEYCRMAYGAMKILMEHYGPQVRFVYRHYPM
CCCCEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
SHWHPSAEAAAECAEAAGAQQKFWQMYRLLHEKPNGLKSEALRHYAGMLGMDLNRFDSDM
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AAHSHLPHIRDDMRGATQWQVRGTPSFFVNGVVQDVTFGMERLQRAIDVALAG
HHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDVAVTAADHAIGPDTARVTVVEYGDFECEYCRMAYGAMKILMEHYGPQVRFVYRHYPM
CCCEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
SHWHPSAEAAAECAEAAGAQQKFWQMYRLLHEKPNGLKSEALRHYAGMLGMDLNRFDSDM
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AAHSHLPHIRDDMRGATQWQVRGTPSFFVNGVVQDVTFGMERLQRAIDVALAG
HHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]