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The map label for this gene is frc [H]

Identifier: 73537982

GI number: 73537982

Start: 790571

End: 791842

Strand: Direct

Name: frc [H]

Synonym: Reut_B4151

Alternate gene names: 73537982

Gene position: 790571-791842 (Clockwise)

Preceding gene: 73537981

Following gene: 73537983

Centisome position: 29.0

GC content: 66.82

Gene sequence:

>1272_bases
ATGCGATGCTGGGCAAGGTCGCCGCCTGAACGGGAGCCCGAAGTGCAGACTCAAGCCAAACCCGCCGGGGCGCTTGCCGG
CCTGCGCGTAATCGACCTCACGCAGATGCTGGCCGGCCCCTTTTGCACGCAGATCCTTGCTGACCACGGGGCGGATGTCA
TCAAGGTCGAAGCGATGACGGGCGACGGCACGCGCGTGACCGGCCCGTTCTGCCCCGACGACGCGCTGCGCGACTTCGGC
GGCTATTTCCAGAGCGTCAACCGCAACAAGCGATCGATCGCACTGGACCTGAAGACCAGCGCCGGCCGCGAGATACTGCG
CCGGCTGATCGACGGGGCCGATGTGGTCGTGGAAAACTTCCGCGCCGGCGTGATGGAGCGCCTTGGCTTGTCCTATGAAA
CCCTGCGGGAAACCAATTCGCGCCTGGTCTATGGCGCGGTGCGGGGGTTCGGCGATCCGCGCAGCGGCGAAAGCCCGTAT
GCGCAGTGGCCGGCCTACGACGTGGTCTCGCAAGCCATGGGCGGCATGATGGGCATCACCGGCCCCGACCGCGACACGCC
CACCAAGATCGGGCCCGGCGTAGGCGACACGGTGCCGGCGCTGATGCTATGTATCGGCATCCTTGCGGCCGTCAACCGCG
TGCGCGAAACCGGTCAGGGCCAGTTCGTCGATGTCGCCATGACCGACGCGGTGCTGGCCATGTGCGAGCGCATCGTCTAC
CAGACCTCCTACACCGGCGCCGTGCCAGCACCAGAAGGCAACCGCCACCCGCTGCTGTGCCCGTTCGGACTGTTCCGCGC
GCGTGACGGCCATGTCTCGATTGCCTGTGCGACCGACGCATTCTGGGAAAAGCTGGCGATTGCCATTGGCCGCCCGGACA
TGGCGCAGGACCCGGCCTTCGCGACCAATGCCGCACGCGTGCAGCACCAGCAGCAGGTCATCGACGCCATCGAGGCCTTT
ACCGCCGTACGCACCAAGGAGGAAATCGCGGTGGCGCTGGGCGGAAAAGTGCCGTTCGGCCCGGTCTACACCTCGGCGGA
AATCTTCGCGGACAGGCACTACGCCGTACGCGAGATGCTGGTGGATGTGGAGCAGCCTGGATCGACGAAGCCCGTAAAGA
TCGCGGGCGTGCCGATCAAGCTCAGCGATACGCCGGGCGCCGTGCGGCGCCGCGCGCCGATGTTCGGCGAGCACACCGAC
GAGATCCTTGGCGGGATCGGCTATGCGGACGACCTGATCCGGGCGCTGAAGGCGCAGCGTGTGGTGGCTTAG

Upstream 100 bases:

>100_bases
GGCTACACCACGCACTTCGCGGCCGAGCGCTACTGGCGTGACGCGCGCCTGACCAAGATCTTCGAAGGCACCTCTGATAT
TCAGATGCGCATCATCTCCG

Downstream 100 bases:

>100_bases
AGGCGTTCGATGAAGGCGCACAGGTACAGACAACACGCGGGAACAACGCAACAACAGGAACAAAGGCATGACCATCAAAG
GCACAGCCTATATCGTCGGA

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRCWARSPPEREPEVQTQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIALDLKTSAGREILRRLIDGADVVVENFRAGVMERLGLSYETLRETNSRLVYGAVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRDTPTKIGPGVGDTVPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QTSYTGAVPAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAIAIGRPDMAQDPAFATNAARVQHQQQVIDAIEAF
TAVRTKEEIAVALGGKVPFGPVYTSAEIFADRHYAVREMLVDVEQPGSTKPVKIAGVPIKLSDTPGAVRRRAPMFGEHTD
EILGGIGYADDLIRALKAQRVVA

Sequences:

>Translated_423_residues
MRCWARSPPEREPEVQTQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIALDLKTSAGREILRRLIDGADVVVENFRAGVMERLGLSYETLRETNSRLVYGAVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRDTPTKIGPGVGDTVPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QTSYTGAVPAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAIAIGRPDMAQDPAFATNAARVQHQQQVIDAIEAF
TAVRTKEEIAVALGGKVPFGPVYTSAEIFADRHYAVREMLVDVEQPGSTKPVKIAGVPIKLSDTPGAVRRRAPMFGEHTD
EILGGIGYADDLIRALKAQRVVA
>Mature_423_residues
MRCWARSPPEREPEVQTQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMTGDGTRVTGPFCPDDALRDFG
GYFQSVNRNKRSIALDLKTSAGREILRRLIDGADVVVENFRAGVMERLGLSYETLRETNSRLVYGAVRGFGDPRSGESPY
AQWPAYDVVSQAMGGMMGITGPDRDTPTKIGPGVGDTVPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
QTSYTGAVPAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAIAIGRPDMAQDPAFATNAARVQHQQQVIDAIEAF
TAVRTKEEIAVALGGKVPFGPVYTSAEIFADRHYAVREMLVDVEQPGSTKPVKIAGVPIKLSDTPGAVRRRAPMFGEHTD
EILGGIGYADDLIRALKAQRVVA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=390, Percent_Identity=29.7435897435897, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI300863124, Length=416, Percent_Identity=28.3653846153846, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI300863126, Length=390, Percent_Identity=27.1794871794872, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI13376042, Length=416, Percent_Identity=25.4807692307692, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI42794625, Length=405, Percent_Identity=28.641975308642, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI266456254, Length=405, Percent_Identity=28.641975308642, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI266458393, Length=271, Percent_Identity=31.3653136531365, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI266458397, Length=283, Percent_Identity=31.4487632508834, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=37.5, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=36.8421052631579, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87082093, Length=365, Percent_Identity=36.4383561643836, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1788717, Length=426, Percent_Identity=34.9765258215962, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786222, Length=405, Percent_Identity=27.4074074074074, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115535051, Length=357, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32564160, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648431, Length=401, Percent_Identity=33.6658354114713, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24585488, Length=372, Percent_Identity=25, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45555; Mature: 45555

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCWARSPPEREPEVQTQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMT
CCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
GDGTRVTGPFCPDDALRDFGGYFQSVNRNKRSIALDLKTSAGREILRRLIDGADVVVENF
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHH
RAGVMERLGLSYETLRETNSRLVYGAVRGFGDPRSGESPYAQWPAYDVVSQAMGGMMGIT
HHHHHHHHCCCHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEECCC
GPDRDTPTKIGPGVGDTVPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
QTSYTGAVPAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAIAIGRPDMAQDPAF
HCCCCCCCCCCCCCCCCEECCHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCH
ATNAARVQHQQQVIDAIEAFTAVRTKEEIAVALGGKVPFGPVYTSAEIFADRHYAVREML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VDVEQPGSTKPVKIAGVPIKLSDTPGAVRRRAPMFGEHTDEILGGIGYADDLIRALKAQR
HHCCCCCCCCCEEEEEEEEEECCCCHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
VVA
CCC
>Mature Secondary Structure
MRCWARSPPEREPEVQTQAKPAGALAGLRVIDLTQMLAGPFCTQILADHGADVIKVEAMT
CCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
GDGTRVTGPFCPDDALRDFGGYFQSVNRNKRSIALDLKTSAGREILRRLIDGADVVVENF
CCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHH
RAGVMERLGLSYETLRETNSRLVYGAVRGFGDPRSGESPYAQWPAYDVVSQAMGGMMGIT
HHHHHHHHCCCHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEECCC
GPDRDTPTKIGPGVGDTVPALMLCIGILAAVNRVRETGQGQFVDVAMTDAVLAMCERIVY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
QTSYTGAVPAPEGNRHPLLCPFGLFRARDGHVSIACATDAFWEKLAIAIGRPDMAQDPAF
HCCCCCCCCCCCCCCCCEECCHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCH
ATNAARVQHQQQVIDAIEAFTAVRTKEEIAVALGGKVPFGPVYTSAEIFADRHYAVREML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VDVEQPGSTKPVKIAGVPIKLSDTPGAVRRRAPMFGEHTDEILGGIGYADDLIRALKAQR
HHCCCCCCCCCEEEEEEEEEECCCCHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
VVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]