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The map label for this gene is 73537983

Identifier: 73537983

GI number: 73537983

Start: 791910

End: 793079

Strand: Direct

Name: 73537983

Synonym: Reut_B4152

Alternate gene names: NA

Gene position: 791910-793079 (Clockwise)

Preceding gene: 73537982

Following gene: 73537984

Centisome position: 29.05

GC content: 66.58

Gene sequence:

>1170_bases
ATGACCATCAAAGGCACAGCCTATATCGTCGGAGCCTACGAGCATCCGACCCGCAAGGCACCGGATAAGAGCGCGGCGCA
ACTGCATGCCGAAAGCGCGCGCGGTGCGCTCGAAGATGCCGGACTATCGTTGTCCGACGTCGACGGCTACTTCTGTGCGG
GCGACGCGCCGGGGCTCGGCGCGGTCAATATGGTCGACTATCTCGGCCTTAAGGTCCGCCATGTCGATTCCACCGATACC
GGCGGCTCCGCCTACCTCGTGCATGTCTCGCACGCCGCGCAGGCGATCGCGGCCGGCAAGTGCAACGTGGCGCTGATCAC
GCTGGCCGGCCGGCCGCGTTCGGAAGGCTCCAGCGGCACGCAGGCGCGCAACTGGGGCGCCAACCTGCCCGATGCGCCGT
TCGAGGCGCCCCTCAACGCGGTCACCGTGAACCTCTACGGCATGGTGGCCATGCGCCATATGTACGAGTACGGCACCACG
CCCGAGCAGCTTGCCTGGATCAAGGTGGCGGCGTCGCACCACGCGCAGCACAACCCGCATGCGATGCTGCGCGACGTGGT
GACGGTGGAAGACGTGCTGAACTCGCCGATGATCTCCGACCCGCTGCGCAAGCTCGACTGCTGCGTGGTCTCGGACGGCG
GCGGCGCGCTGATCGTGGCACGTCGCGAGATTGCAGCAAAGCTGGACCGTCCGCGCATCCGCGTGCTGGGCGCGGGCGAG
CACGTCAAAGGCCAGCTTGGCGGCGAGGTGGACCTGAGCTGGTCCGCCGCACGCGTATCGGGCGCGGCGGCGTTTGCCGA
AGCTGGCGTGACGCCGACCGACATCAAGTACGCCTCAATCTACGACAGCTTCACGATCACCGTGCTGATGCAACTGGAAG
ATCTCGGCTTCTGCAAGAAGGGAGACGGCGGCAAGTTCGTGATGGACGGCAACCTGATCTCCGGCGTCGGCAAGCTGCCC
ATCAATACCGATGGCGGCGGCCTGTGCAACAACCATCCCGCCAACCGCGGCGGCATCACCAAGGTGATCGAAGCCGTGCG
CCAGCTGCGTGGCGAGGCCCATCCCGCTGTGCAGGTGCCCAACTGCGACCTTGCACTCGCGCAAGGCACGGGCGGCTACC
TCGGCAGCCGGCACGGCAGCGCCACGCTGATCCTGGAACGCGATCAATGA

Upstream 100 bases:

>100_bases
CGGGCGCTGAAGGCGCAGCGTGTGGTGGCTTAGAGGCGTTCGATGAAGGCGCACAGGTACAGACAACACGCGGGAACAAC
GCAACAACAGGAACAAAGGC

Downstream 100 bases:

>100_bases
GCGACAACACGGGAGCCATCGAATGACCACCCCTCATGTCCCACTGGCCTACCAGGCCCCGGACGAACAGCCGGACAACA
CACCGTTCTGGCAGGCCGCG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTIKGTAYIVGAYEHPTRKAPDKSAAQLHAESARGALEDAGLSLSDVDGYFCAGDAPGLGAVNMVDYLGLKVRHVDSTDT
GGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPLNAVTVNLYGMVAMRHMYEYGTT
PEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMISDPLRKLDCCVVSDGGGALIVARREIAAKLDRPRIRVLGAGE
HVKGQLGGEVDLSWSAARVSGAAAFAEAGVTPTDIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLP
INTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVPNCDLALAQGTGGYLGSRHGSATLILERDQ

Sequences:

>Translated_389_residues
MTIKGTAYIVGAYEHPTRKAPDKSAAQLHAESARGALEDAGLSLSDVDGYFCAGDAPGLGAVNMVDYLGLKVRHVDSTDT
GGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPLNAVTVNLYGMVAMRHMYEYGTT
PEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMISDPLRKLDCCVVSDGGGALIVARREIAAKLDRPRIRVLGAGE
HVKGQLGGEVDLSWSAARVSGAAAFAEAGVTPTDIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLP
INTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVPNCDLALAQGTGGYLGSRHGSATLILERDQ
>Mature_388_residues
TIKGTAYIVGAYEHPTRKAPDKSAAQLHAESARGALEDAGLSLSDVDGYFCAGDAPGLGAVNMVDYLGLKVRHVDSTDTG
GSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPLNAVTVNLYGMVAMRHMYEYGTTP
EQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMISDPLRKLDCCVVSDGGGALIVARREIAAKLDRPRIRVLGAGEH
VKGQLGGEVDLSWSAARVSGAAAFAEAGVTPTDIKYASIYDSFTITVLMQLEDLGFCKKGDGGKFVMDGNLISGVGKLPI
NTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVPNCDLALAQGTGGYLGSRHGSATLILERDQ

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=379, Percent_Identity=27.9683377308707, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI302344762, Length=242, Percent_Identity=30.9917355371901, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI302344760, Length=242, Percent_Identity=30.9917355371901, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI302344767, Length=242, Percent_Identity=30.9917355371901, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI55956775, Length=204, Percent_Identity=29.9019607843137, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=367, Percent_Identity=26.7029972752044, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19921506, Length=398, Percent_Identity=28.643216080402, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24585051, Length=391, Percent_Identity=28.6445012787724, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40753; Mature: 40621

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKGTAYIVGAYEHPTRKAPDKSAAQLHAESARGALEDAGLSLSDVDGYFCAGDAPGLG
CEECEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCEEECCCCEEECCCCCCCC
AVNMVDYLGLKVRHVDSTDTGGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
QARNWGANLPDAPFEAPLNAVTVNLYGMVAMRHMYEYGTTPEQLAWIKVAASHHAQHNPH
CCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHEEEEEEEEHHCCCCCCH
AMLRDVVTVEDVLNSPMISDPLRKLDCCVVSDGGGALIVARREIAAKLDRPRIRVLGAGE
HHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCCEEEEEEHHHHHHCCCCEEEEEECCC
HVKGQLGGEVDLSWSAARVSGAAAFAEAGVTPTDIKYASIYDSFTITVLMQLEDLGFCKK
CCCCCCCCEEEECCCHHHHCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEEEHHCCCEEC
GDGGKFVMDGNLISGVGKLPINTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVP
CCCCEEEECCCEECCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECC
NCDLALAQGTGGYLGSRHGSATLILERDQ
CCCEEEECCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TIKGTAYIVGAYEHPTRKAPDKSAAQLHAESARGALEDAGLSLSDVDGYFCAGDAPGLG
EECEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCEEECCCCEEECCCCCCCC
AVNMVDYLGLKVRHVDSTDTGGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
QARNWGANLPDAPFEAPLNAVTVNLYGMVAMRHMYEYGTTPEQLAWIKVAASHHAQHNPH
CCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHEEEEEEEEHHCCCCCCH
AMLRDVVTVEDVLNSPMISDPLRKLDCCVVSDGGGALIVARREIAAKLDRPRIRVLGAGE
HHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCCEEEEEEHHHHHHCCCCEEEEEECCC
HVKGQLGGEVDLSWSAARVSGAAAFAEAGVTPTDIKYASIYDSFTITVLMQLEDLGFCKK
CCCCCCCCEEEECCCHHHHCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEEEHHCCCEEC
GDGGKFVMDGNLISGVGKLPINTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVP
CCCCEEEECCCEECCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECC
NCDLALAQGTGGYLGSRHGSATLILERDQ
CCCEEEECCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]