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The map label for this gene is acdA [H]

Identifier: 73537981

GI number: 73537981

Start: 789433

End: 790599

Strand: Direct

Name: acdA [H]

Synonym: Reut_B4150

Alternate gene names: 73537981

Gene position: 789433-790599 (Clockwise)

Preceding gene: 73537977

Following gene: 73537982

Centisome position: 28.96

GC content: 64.52

Gene sequence:

>1167_bases
GTGCAGAAACTGACCGAAGAACGCCGCATGATCCAGGAGGCCGCGCGCCAGTTCACGATGGAGCGCGTGCTGCCCATCGC
CAACAAGCGGGACCCCGAGAAGGGCAAGATCCCGCGCGAGCTGATCGACGAGATGGCCGAACTCGGCTACTTCGGCATCC
TGATTCCCGAGGAGTACGGCGGTCTGGGTCTGGGCGCCTACGAGTACTGCCTGGTCGCGGAACAACTGTCGCGTGGCTGG
ATGAGCGTCGGCAGCCTGATCGCGCGTGGCAACGGCCTGATCGGCGCGCTCAAGGGCCTGTCGTCCGAGCGCAAGGCCGA
GTTTCTGCCGCGCATGGCGCGCGGTGAATTCCTCGGTGCATTCTCACTGTCCGAGCCCAATGCCGGCTCCGACGTGGCCA
ATATCTCGTGCCGCGCGGTGCGCGATGGCGACGACTGGCTCATCACCGGCAACAAGTACTGGTGCACGTTTGCCGACGAG
GCCGACTTCATCCTGGTCATCTGCCGCACCGACCCGGTCATCGACCCGAAGGCGCGCCACAAGGGTCTGTCTGCCTTCAT
GGTGGAAAAGCCGCGCGGCGAACTGCCCGAGGGCGTCAAGGGTAGCGTGATTCCCAAGATCGGCTACCACGGCTGGACCA
CGTGGGAACTGGCCTTCGATGGCTGCCGCGTGCCACATTCGAAGATGGTCGGCGAGGAAGGCAAGGCGTTCTACCTGACC
ACGGCCGGGCTTGAGACTGCACGGGCCCATACGGCCGCGCGCTCGATCGGCCTCGCACAAGGCAGTCTCGAGGACTCCAT
TCAATACGCGAAGGGCCGCAACCAGTTCGGCAACCCGATCGGCAACTTCCAGGCGATTCGCTTCAAGATCGCCGACATGG
CCACGCAGATAGAGGCCTCGCGCGCGCTGCTCTACACGGTGTGCGAGAAGATCGACGAAGGCGTGCGCGCCGACACCGAA
GCGTCGATGGTCAAGCTGTTCGCGAGCGAGATGTGTGAGCGGGTGACCAGCGAAGGCCTGCAGATCCACGGCGGCGCGGG
CTACACCACGCACTTCGCGGCCGAGCGCTACTGGCGTGACGCGCGCCTGACCAAGATCTTCGAAGGCACCTCTGATATTC
AGATGCGCATCATCTCCGATGCGATGCTGGGCAAGGTCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGGATAAGTCTTGCCTATCCCCATCCTCCTCCCGCTATTATGTCCGTACATACACGCCGCCGATATGGCGGAATCCAG
ACCACCGCCAGGAGTGCAAG

Downstream 100 bases:

>100_bases
ACGGGAGCCCGAAGTGCAGACTCAAGCCAAACCCGCCGGGGCGCTTGCCGGCCTGCGCGTAATCGACCTCACGCAGATGC
TGGCCGGCCCCTTTTGCACG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MQKLTEERRMIQEAARQFTMERVLPIANKRDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYEYCLVAEQLSRGW
MSVGSLIARGNGLIGALKGLSSERKAEFLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLITGNKYWCTFADE
ADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKMVGEEGKAFYLT
TAGLETARAHTAARSIGLAQGSLEDSIQYAKGRNQFGNPIGNFQAIRFKIADMATQIEASRALLYTVCEKIDEGVRADTE
ASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSDIQMRIISDAMLGKVAA

Sequences:

>Translated_388_residues
MQKLTEERRMIQEAARQFTMERVLPIANKRDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYEYCLVAEQLSRGW
MSVGSLIARGNGLIGALKGLSSERKAEFLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLITGNKYWCTFADE
ADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKMVGEEGKAFYLT
TAGLETARAHTAARSIGLAQGSLEDSIQYAKGRNQFGNPIGNFQAIRFKIADMATQIEASRALLYTVCEKIDEGVRADTE
ASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSDIQMRIISDAMLGKVAA
>Mature_388_residues
MQKLTEERRMIQEAARQFTMERVLPIANKRDPEKGKIPRELIDEMAELGYFGILIPEEYGGLGLGAYEYCLVAEQLSRGW
MSVGSLIARGNGLIGALKGLSSERKAEFLPRMARGEFLGAFSLSEPNAGSDVANISCRAVRDGDDWLITGNKYWCTFADE
ADFILVICRTDPVIDPKARHKGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKMVGEEGKAFYLT
TAGLETARAHTAARSIGLAQGSLEDSIQYAKGRNQFGNPIGNFQAIRFKIADMATQIEASRALLYTVCEKIDEGVRADTE
ASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRDARLTKIFEGTSDIQMRIISDAMLGKVAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=36.1256544502618, Blast_Score=242, Evalue=6e-64,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=36.8146214099217, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI226958414, Length=362, Percent_Identity=35.6353591160221, Blast_Score=228, Evalue=8e-60,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=34.1207349081365, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=33.160621761658, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=33.160621761658, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI21361497, Length=376, Percent_Identity=32.9787234042553, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=31.331592689295, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI76496475, Length=380, Percent_Identity=33.6842105263158, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4557235, Length=380, Percent_Identity=33.6842105263158, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=30.1587301587302, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI4503943, Length=406, Percent_Identity=28.8177339901478, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7669494, Length=390, Percent_Identity=28.2051282051282, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI38505218, Length=397, Percent_Identity=24.6851385390428, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=31.1688311688312, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786223, Length=346, Percent_Identity=26.878612716763, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87082384, Length=288, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=34.2857142857143, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=32.8165374677003, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=34.0314136125654, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17534899, Length=388, Percent_Identity=32.7319587628866, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=33.3333333333333, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=32.1052631578947, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=362, Percent_Identity=30.3867403314917, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=35.5932203389831, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=30.8093994778068, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=30.4, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=304, Percent_Identity=28.9473684210526, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=286, Percent_Identity=29.020979020979, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=33.7552742616034, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17534353, Length=393, Percent_Identity=26.7175572519084, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=29.3388429752066, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=368, Percent_Identity=26.3586956521739, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17531913, Length=173, Percent_Identity=28.9017341040462, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=26.7657992565056, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=26.7657992565056, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=36.6666666666667, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=35.9580052493438, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=34.9081364829396, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24666513, Length=387, Percent_Identity=32.5581395348837, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=33.8582677165354, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI281363737, Length=351, Percent_Identity=32.4786324786325, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19920834, Length=398, Percent_Identity=27.1356783919598, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42784; Mature: 42784

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLTEERRMIQEAARQFTMERVLPIANKRDPEKGKIPRELIDEMAELGYFGILIPEEYG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCC
GLGLGAYEYCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSSERKAEFLPRMARGEFLGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEE
FSLSEPNAGSDVANISCRAVRDGDDWLITGNKYWCTFADEADFILVICRTDPVIDPKARH
EECCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHHH
KGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKMVGEEGKAFYLT
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCCEEEEE
TAGLETARAHTAARSIGLAQGSLEDSIQYAKGRNQFGNPIGNFQAIRFKIADMATQIEAS
ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
RALLYTVCEKIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
ARLTKIFEGTSDIQMRIISDAMLGKVAA
HHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKLTEERRMIQEAARQFTMERVLPIANKRDPEKGKIPRELIDEMAELGYFGILIPEEYG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCC
GLGLGAYEYCLVAEQLSRGWMSVGSLIARGNGLIGALKGLSSERKAEFLPRMARGEFLGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEE
FSLSEPNAGSDVANISCRAVRDGDDWLITGNKYWCTFADEADFILVICRTDPVIDPKARH
EECCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHHH
KGLSAFMVEKPRGELPEGVKGSVIPKIGYHGWTTWELAFDGCRVPHSKMVGEEGKAFYLT
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCCEEEEE
TAGLETARAHTAARSIGLAQGSLEDSIQYAKGRNQFGNPIGNFQAIRFKIADMATQIEAS
ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
RALLYTVCEKIDEGVRADTEASMVKLFASEMCERVTSEGLQIHGGAGYTTHFAAERYWRD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
ARLTKIFEGTSDIQMRIISDAMLGKVAA
HHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]