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The map label for this gene is cph2 [H]

Identifier: 73537858

GI number: 73537858

Start: 665702

End: 667207

Strand: Reverse

Name: cph2 [H]

Synonym: Reut_B4025

Alternate gene names: 73537858

Gene position: 667207-665702 (Counterclockwise)

Preceding gene: 73537859

Following gene: 73537854

Centisome position: 24.47

GC content: 68.79

Gene sequence:

>1506_bases
ATGCCGACGGCGCTCTCCTGCCGCCCTGCCTGCCGTATGATCGTAGTTGCGCCACATCGGACACCGCGATACTGCCTGCA
CGGCAACGTGCAATCGCAGTGGCAAAATACGATCACAACGACAGAACGGGGAAGTGTGGACAGTAGCCGGCATCTTGCCG
GCCTTGCCTGCAAGAGAGATTGCATGCACCAAGACGACGCCGACGACAGCGCCGGTCAACGTGCCGGAAACGCATATGAC
ATGGTCCAGCCGGCCGCCTTCGTGGCCGCGCTGGGGAATTGCCGCGCCACTTTCGCTGGCGCACCGTTGGTCATCCTCGT
CATTCGACTGGACCGCTTTGCCAGCGCGTGCGAATCCGCGGGCCCCCGGCGGGCTGCGCATCTGCGCCAACTCGTCCAGG
CGCGGCTCGCGCGATTGCTGCTGCCGGAAGCGCGCATGTACTGGCTCGGGCCCGCGGACCTGGCGGTGGTGACGCCATTG
CCGGCGGCGACGCAAGACCCGGCACGGCTCGGACAACGCATGGCCGACGAGCTGGGCCGACCCTTCACGCTGGACGGCTT
CGAGCTGTTCCTGTCCTGCAGCATCGGCATGTCGCTCGACCATCCCGACGTGGCCGCCGAACGCAGCCTGCAGCACGCGT
TTGACGCCATGCTGCGGATCTGCCGCCAAGGCGGCGACGGGTTGGCCAGCGCCATGCGTGCCGGCACGCCCGCCGCGGAC
CAGATGCTCGCCGCGCTGCCCCAGGCGCTTGAGCGCGGCGAACTGAGCTTGCACCTCCAGCCGCGCGCCGATTTCGCCGG
CGCCCGCATCAGCGGCTATTCGGTCCGCCTGCGCTGGCGCCATCCCGCGCTCGGGCGGGTTGCGCCGCAGGACTTCCTGC
CCGCGCTCGAAGGCTTGGGCCTGATGGGCCCGGTCGGCAACTGGCTGCTCGGCAGCTTGGCGCCGCTGGCACGCGCAGCC
GAAGATGTCGGGCCGCTGCAGTTCACCCTGCTGGCATCGAGTGCGCAGCTGCATCAGCTTGAAATGGTCGATGCGCTTGC
GCGAACGCTTGATGCTGGTGCCGTCGCGCCGGAGCGGCTCTGCATCGAAGTGCCCTCCACCAACCTGCCGGACGACCCGG
AACTGATCGGAAGTTTCGAAGCCTTGCGCCAGCGCGGCCTGCAACTGTCGCTCAGCGACTTCGACGGCCGGCCGGAAAGC
CTGGAGACCTTTGCCTGGTTGCGTCCCGACCGGGTCACGCTGGACGTGCGCAGCCTCGGGCATGCCGACCAGCCCGCCAA
CGCCGCGGCAGGGCTGCGCGACGCGTGCACGGTGGCGCGCAAGGCGGGCGTCATGGTTTGTGCAAAGGGCGTGGAAACGC
GCAAGCAGCTGGAACAGGTGCATGCCTGGGGGTGCCACAGCATCCAGGGCTACCTGCTGGCGCAGCCATTCCCGGCCAAC
TGGCTCGCGCAGACGCACTGGGCCATCCAGCAGCGCGCGCGGGAACTGCTCGGGCCGGCGGGATGA

Upstream 100 bases:

>100_bases
GACGAAACCACGGGCTGATTCCGGCACCGCCCTTCGTCGTCTTTCCCGCGCATCGGCAATTCGGGCGGCTGTCAAGGCCG
GCGTACCGCGCACCGGCTCG

Downstream 100 bases:

>100_bases
CGCCAGCGGCGAGCGTCCATGCGCCTCCCAGCCCAGTACGATTTACAAATTGCGACACATCACACGTGATGCGCACGGCC
ACTGGCGGTAAAATCTGCCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MPTALSCRPACRMIVVAPHRTPRYCLHGNVQSQWQNTITTTERGSVDSSRHLAGLACKRDCMHQDDADDSAGQRAGNAYD
MVQPAAFVAALGNCRATFAGAPLVILVIRLDRFASACESAGPRRAAHLRQLVQARLARLLLPEARMYWLGPADLAVVTPL
PAATQDPARLGQRMADELGRPFTLDGFELFLSCSIGMSLDHPDVAAERSLQHAFDAMLRICRQGGDGLASAMRAGTPAAD
QMLAALPQALERGELSLHLQPRADFAGARISGYSVRLRWRHPALGRVAPQDFLPALEGLGLMGPVGNWLLGSLAPLARAA
EDVGPLQFTLLASSAQLHQLEMVDALARTLDAGAVAPERLCIEVPSTNLPDDPELIGSFEALRQRGLQLSLSDFDGRPES
LETFAWLRPDRVTLDVRSLGHADQPANAAAGLRDACTVARKAGVMVCAKGVETRKQLEQVHAWGCHSIQGYLLAQPFPAN
WLAQTHWAIQQRARELLGPAG

Sequences:

>Translated_501_residues
MPTALSCRPACRMIVVAPHRTPRYCLHGNVQSQWQNTITTTERGSVDSSRHLAGLACKRDCMHQDDADDSAGQRAGNAYD
MVQPAAFVAALGNCRATFAGAPLVILVIRLDRFASACESAGPRRAAHLRQLVQARLARLLLPEARMYWLGPADLAVVTPL
PAATQDPARLGQRMADELGRPFTLDGFELFLSCSIGMSLDHPDVAAERSLQHAFDAMLRICRQGGDGLASAMRAGTPAAD
QMLAALPQALERGELSLHLQPRADFAGARISGYSVRLRWRHPALGRVAPQDFLPALEGLGLMGPVGNWLLGSLAPLARAA
EDVGPLQFTLLASSAQLHQLEMVDALARTLDAGAVAPERLCIEVPSTNLPDDPELIGSFEALRQRGLQLSLSDFDGRPES
LETFAWLRPDRVTLDVRSLGHADQPANAAAGLRDACTVARKAGVMVCAKGVETRKQLEQVHAWGCHSIQGYLLAQPFPAN
WLAQTHWAIQQRARELLGPAG
>Mature_500_residues
PTALSCRPACRMIVVAPHRTPRYCLHGNVQSQWQNTITTTERGSVDSSRHLAGLACKRDCMHQDDADDSAGQRAGNAYDM
VQPAAFVAALGNCRATFAGAPLVILVIRLDRFASACESAGPRRAAHLRQLVQARLARLLLPEARMYWLGPADLAVVTPLP
AATQDPARLGQRMADELGRPFTLDGFELFLSCSIGMSLDHPDVAAERSLQHAFDAMLRICRQGGDGLASAMRAGTPAADQ
MLAALPQALERGELSLHLQPRADFAGARISGYSVRLRWRHPALGRVAPQDFLPALEGLGLMGPVGNWLLGSLAPLARAAE
DVGPLQFTLLASSAQLHQLEMVDALARTLDAGAVAPERLCIEVPSTNLPDDPELIGSFEALRQRGLQLSLSDFDGRPESL
ETFAWLRPDRVTLDVRSLGHADQPANAAAGLRDACTVARKAGVMVCAKGVETRKQLEQVHAWGCHSIQGYLLAQPFPANW
LAQTHWAIQQRARELLGPAG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=390, Percent_Identity=24.1025641025641, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1787541, Length=324, Percent_Identity=27.1604938271605, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786507, Length=256, Percent_Identity=25, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787055, Length=238, Percent_Identity=25.2100840336134, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI226510982, Length=375, Percent_Identity=24, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788502, Length=245, Percent_Identity=24.0816326530612, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081845, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=23.046875, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=25.1028806584362, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 54048; Mature: 53916

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTALSCRPACRMIVVAPHRTPRYCLHGNVQSQWQNTITTTERGSVDSSRHLAGLACKRD
CCCCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
CMHQDDADDSAGQRAGNAYDMVQPAAFVAALGNCRATFAGAPLVILVIRLDRFASACESA
HCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCC
GPRRAAHLRQLVQARLARLLLPEARMYWLGPADLAVVTPLPAATQDPARLGQRMADELGR
CCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCC
PFTLDGFELFLSCSIGMSLDHPDVAAERSLQHAFDAMLRICRQGGDGLASAMRAGTPAAD
CEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
QMLAALPQALERGELSLHLQPRADFAGARISGYSVRLRWRHPALGRVAPQDFLPALEGLG
HHHHHHHHHHHCCCEEEEECCCCCCCCCEECCEEEEEEECCCCCCCCCCHHHHHHHHCCC
LMGPVGNWLLGSLAPLARAAEDVGPLQFTLLASSAQLHQLEMVDALARTLDAGAVAPERL
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCE
CIEVPSTNLPDDPELIGSFEALRQRGLQLSLSDFDGRPESLETFAWLRPDRVTLDVRSLG
EEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHEECCCCEEEEHHHCC
HADQPANAAAGLRDACTVARKAGVMVCAKGVETRKQLEQVHAWGCHSIQGYLLAQPFPAN
CCCCCCHHHCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
WLAQTHWAIQQRARELLGPAG
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTALSCRPACRMIVVAPHRTPRYCLHGNVQSQWQNTITTTERGSVDSSRHLAGLACKRD
CCCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
CMHQDDADDSAGQRAGNAYDMVQPAAFVAALGNCRATFAGAPLVILVIRLDRFASACESA
HCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCC
GPRRAAHLRQLVQARLARLLLPEARMYWLGPADLAVVTPLPAATQDPARLGQRMADELGR
CCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCC
PFTLDGFELFLSCSIGMSLDHPDVAAERSLQHAFDAMLRICRQGGDGLASAMRAGTPAAD
CEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
QMLAALPQALERGELSLHLQPRADFAGARISGYSVRLRWRHPALGRVAPQDFLPALEGLG
HHHHHHHHHHHCCCEEEEECCCCCCCCCEECCEEEEEEECCCCCCCCCCHHHHHHHHCCC
LMGPVGNWLLGSLAPLARAAEDVGPLQFTLLASSAQLHQLEMVDALARTLDAGAVAPERL
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCE
CIEVPSTNLPDDPELIGSFEALRQRGLQLSLSDFDGRPESLETFAWLRPDRVTLDVRSLG
EEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHEECCCCEEEEHHHCC
HADQPANAAAGLRDACTVARKAGVMVCAKGVETRKQLEQVHAWGCHSIQGYLLAQPFPAN
CCCCCCHHHCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
WLAQTHWAIQQRARELLGPAG
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]