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The map label for this gene is ytfL [C]

Identifier: 73537859

GI number: 73537859

Start: 667290

End: 668603

Strand: Reverse

Name: ytfL [C]

Synonym: Reut_B4026

Alternate gene names: 73537859

Gene position: 668603-667290 (Counterclockwise)

Preceding gene: 73537861

Following gene: 73537858

Centisome position: 24.53

GC content: 65.14

Gene sequence:

>1314_bases
ATGGAAATTGCCATACTGCTGGCGCTGATTCTGCTCAACGGTCTGTTCGCCATGTCCGAGATCGCGCTGGTCACCGCACG
CCGGGCCCGGCTGCAGCGCCAGGTGGAAGAAGGCGACCGCGGAGCCATTGAAGCCATCAAGCTTGGCGAAGACCCAACGC
GGTTCCTGTCGACCGTTCAGATCGGGATCACCTCGATCGGCGTGCTCAACGGCGTAGTGGGCGAATCGACCCTGGCACAA
CCGCTGGGCGTGTGGCTTCAGGGGCTTGGGCTGCCGCAGACCACGGCCGGCTATGTGGCAACAGCCATCGTAGTGGCCGG
CCTGACCTATTTCTCGATCGTGCTGGGCGAACTGGTGCCCAAGCGCCTGGGCCAGATGGCGCCGGAGACCATCGCCCGGC
TGGCGGCGCGCCCGATCTCCTGGCTCGCCGTGGCCAGCACGCCGTTCGTCAAGTTGCTGTCGGGATCCACGCGTCTGGTG
CTGCGCCTACTCGGCGTCAACACAAACCGCGGCCCCGGCGTGACCGAAGAAGAAATTCACGCGCTGCTGGTCGAGGGCTC
CGAGGCCGGCATCATCGAGCAGCACGAGCACACCATGGTGCGCAACGTGTTCCGCCTCGATGACCGGCAACTCGCTTCGC
TGATGGTGCCGCGCGGAGACGTGGTGTATCTCGACGTGGAAGTGCCGCTGGATGAGAACCTCAAGCGTATCGAGGAATCG
GATCATTCCCGCTTTCCGGTCGTGCGTGGCGGCATGCATGACATCGTCGGCGTGGTGAGCGCGCGCCAGTTGCTGGCCCG
CCGCCTGCGCGGCGAAGAAGCCGACCTGATGGCCGCGGTGCAGCCGGCGGTGTTCGTGCCGGAGAGCGTCACGGGCATGG
AGCTGCTGGAAAACTTCCGCGGCTCGGGCGGCCAGATCGCCTTCGTCATCGACGAGTACGGCGAAGTGCTGGGCCTGGTC
ACGCTGCAGGACCTGATCGAAGCCATCACCGGCGAGTTCAAGCCGGACAGCGCGGACGAGGAATGGGCCATCCAGCGCGA
AGACGGCTCCTGGCTGCTCGACGGCCTGATCCCGATTCCCGAACTGAAGGATCGCATCGGCCTGCGCCAGGTCCCCGAGG
AAGAGAAAGAGCGCTATCACACGCTCTCCGGCATGCTCCTGCTGCTGCTTGGCCGGTTGCCCCAGACCGCGGACAGTGTC
CAGTGGGGAGACTGGCGCTTCGAGATCCTTGATATGGACGGCAAGCGCATCGATAAGGTCCTGGCCTCGCGGGTAGCGGC
ATCGGAAGGACCAGAAGACGAAACCACGGGCTGA

Upstream 100 bases:

>100_bases
TACCTCAGTTTGCGCCCTATTCTGCACACCACGACAAGGTGTAACAGGCGAATGGTATGCTTGATCTTTTAACCCCCGCG
CGCAAAGGGCGCGCACCCTG

Downstream 100 bases:

>100_bases
TTCCGGCACCGCCCTTCGTCGTCTTTCCCGCGCATCGGCAATTCGGGCGGCTGTCAAGGCCGGCGTACCGCGCACCGGCT
CGATGCCGACGGCGCTCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MEIAILLALILLNGLFAMSEIALVTARRARLQRQVEEGDRGAIEAIKLGEDPTRFLSTVQIGITSIGVLNGVVGESTLAQ
PLGVWLQGLGLPQTTAGYVATAIVVAGLTYFSIVLGELVPKRLGQMAPETIARLAARPISWLAVASTPFVKLLSGSTRLV
LRLLGVNTNRGPGVTEEEIHALLVEGSEAGIIEQHEHTMVRNVFRLDDRQLASLMVPRGDVVYLDVEVPLDENLKRIEES
DHSRFPVVRGGMHDIVGVVSARQLLARRLRGEEADLMAAVQPAVFVPESVTGMELLENFRGSGGQIAFVIDEYGEVLGLV
TLQDLIEAITGEFKPDSADEEWAIQREDGSWLLDGLIPIPELKDRIGLRQVPEEEKERYHTLSGMLLLLLGRLPQTADSV
QWGDWRFEILDMDGKRIDKVLASRVAASEGPEDETTG

Sequences:

>Translated_437_residues
MEIAILLALILLNGLFAMSEIALVTARRARLQRQVEEGDRGAIEAIKLGEDPTRFLSTVQIGITSIGVLNGVVGESTLAQ
PLGVWLQGLGLPQTTAGYVATAIVVAGLTYFSIVLGELVPKRLGQMAPETIARLAARPISWLAVASTPFVKLLSGSTRLV
LRLLGVNTNRGPGVTEEEIHALLVEGSEAGIIEQHEHTMVRNVFRLDDRQLASLMVPRGDVVYLDVEVPLDENLKRIEES
DHSRFPVVRGGMHDIVGVVSARQLLARRLRGEEADLMAAVQPAVFVPESVTGMELLENFRGSGGQIAFVIDEYGEVLGLV
TLQDLIEAITGEFKPDSADEEWAIQREDGSWLLDGLIPIPELKDRIGLRQVPEEEKERYHTLSGMLLLLLGRLPQTADSV
QWGDWRFEILDMDGKRIDKVLASRVAASEGPEDETTG
>Mature_437_residues
MEIAILLALILLNGLFAMSEIALVTARRARLQRQVEEGDRGAIEAIKLGEDPTRFLSTVQIGITSIGVLNGVVGESTLAQ
PLGVWLQGLGLPQTTAGYVATAIVVAGLTYFSIVLGELVPKRLGQMAPETIARLAARPISWLAVASTPFVKLLSGSTRLV
LRLLGVNTNRGPGVTEEEIHALLVEGSEAGIIEQHEHTMVRNVFRLDDRQLASLMVPRGDVVYLDVEVPLDENLKRIEES
DHSRFPVVRGGMHDIVGVVSARQLLARRLRGEEADLMAAVQPAVFVPESVTGMELLENFRGSGGQIAFVIDEYGEVLGLV
TLQDLIEAITGEFKPDSADEEWAIQREDGSWLLDGLIPIPELKDRIGLRQVPEEEKERYHTLSGMLLLLLGRLPQTADSV
QWGDWRFEILDMDGKRIDKVLASRVAASEGPEDETTG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=382, Percent_Identity=29.3193717277487, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=29.03981264637, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI145693175, Length=416, Percent_Identity=26.4423076923077, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87082033, Length=270, Percent_Identity=34.0740740740741, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788119, Length=245, Percent_Identity=31.4285714285714, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=30.3149606299213, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47738; Mature: 47738

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAILLALILLNGLFAMSEIALVTARRARLQRQVEEGDRGAIEAIKLGEDPTRFLSTVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHH
IGITSIGVLNGVVGESTLAQPLGVWLQGLGLPQTTAGYVATAIVVAGLTYFSIVLGELVP
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLGQMAPETIARLAARPISWLAVASTPFVKLLSGSTRLVLRLLGVNTNRGPGVTEEEIH
HHHHCCCHHHHHHHHCCCCHHEEECCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHH
ALLVEGSEAGIIEQHEHTMVRNVFRLDDRQLASLMVPRGDVVYLDVEVPLDENLKRIEES
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHC
DHSRFPVVRGGMHDIVGVVSARQLLARRLRGEEADLMAAVQPAVFVPESVTGMELLENFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCCCHHHHHHHHHC
GSGGQIAFVIDEYGEVLGLVTLQDLIEAITGEFKPDSADEEWAIQREDGSWLLDGLIPIP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECCCCCCH
ELKDRIGLRQVPEEEKERYHTLSGMLLLLLGRLPQTADSVQWGDWRFEILDMDGKRIDKV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHH
LASRVAASEGPEDETTG
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEIAILLALILLNGLFAMSEIALVTARRARLQRQVEEGDRGAIEAIKLGEDPTRFLSTVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHH
IGITSIGVLNGVVGESTLAQPLGVWLQGLGLPQTTAGYVATAIVVAGLTYFSIVLGELVP
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLGQMAPETIARLAARPISWLAVASTPFVKLLSGSTRLVLRLLGVNTNRGPGVTEEEIH
HHHHCCCHHHHHHHHCCCCHHEEECCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHH
ALLVEGSEAGIIEQHEHTMVRNVFRLDDRQLASLMVPRGDVVYLDVEVPLDENLKRIEES
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHC
DHSRFPVVRGGMHDIVGVVSARQLLARRLRGEEADLMAAVQPAVFVPESVTGMELLENFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCCCHHHHHHHHHC
GSGGQIAFVIDEYGEVLGLVTLQDLIEAITGEFKPDSADEEWAIQREDGSWLLDGLIPIP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECCCCCCH
ELKDRIGLRQVPEEEKERYHTLSGMLLLLLGRLPQTADSVQWGDWRFEILDMDGKRIDKV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHH
LASRVAASEGPEDETTG
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]