Click here to switch to the map view.

The map label for this gene is gntP [H]

Identifier: 73537851

GI number: 73537851

Start: 657932

End: 659293

Strand: Reverse

Name: gntP [H]

Synonym: Reut_B4018

Alternate gene names: 73537851

Gene position: 659293-657932 (Counterclockwise)

Preceding gene: 73537852

Following gene: 73537850

Centisome position: 24.18

GC content: 64.46

Gene sequence:

>1362_bases
ATGGGTGCCGTCACCGGAACCACACTGTTGGTGTACGCGCTGATCGCCGTGATCGCCCTGGTCATACTGATCGCGCGCTT
CAAGCTCAACCCCTTCATCACCCTGGTCGTCGTCTCTGTGCTGCTCGGCTTCGCCGTGGGCATGCCCATGGGCGACATCA
TCAAGTCGTTCGAAGCCGGCGTAGGCGGCACGCTCGGGCATATTGCCCTGGTGGTGGGCCTCGGCACCATGCTCGGCAAG
ATGATGGCGGAATCGGGCGGCGCCGAGCGCATCGCCCGCACGCTGATCGATTTCTTCGGCGAGAAGAACGTGCACTGGGC
CATGGTGACCATCGCCTTCATCGTCGGCCTGCCGGTCTTCTTTGAAGTCGGCTTCGTGCTGCTGGTGCCGATCGCCTTCA
ACGTGGCCAAGCGCACCGGCACGTCGATGGTGCTGGTCGGCATTCCGATGGTGGCGGGCCTGTCCGTCGTGCATGGCCTG
ATTCCCCCGCACCCGGCAGCGCTGCTCGCGGTCACCGCCTATGGCGCCGACATCGGCCGCACCATCATGTACGCGCTGAT
CGTCGGCATTCCGACCGCGGCCATTGCCGGCCCGCTGTTCGCGAAACTGATGGACCGCTACGTCAAGCTGCCCGATGTCA
ACCCGCTGGCCGCGCAGTTCACCGAGGAAGACGAGAAGGTCAAGGAATCGCACGACCTGCCGGGCTTCGGCATCACGGTG
TTCACGATCCTGCTGCCGGTGCTGCTGATGCTGATCGGCAGCTGGGCCGACCTGTTCACGACGCCCAAGACCTTTGCCAA
CGACTTCCTCAAGCTGATCGGCAACTCGGTCATGGCGCTGCTGATCGCCGCGCTGGTCAGCTTCTACACCTTTGGCAAAG
CGCGCGGCTTCAATCGCGACGCGATCCTGAAGTTCACCAACGAGTGCGTGGCGCCTACAGCCATCATCACGCTCGTGGTC
GGCGCCGGCGGCGGCTTTGGCCGCATCCTGCGCGATTCCGGCATTTCCAACGCCATCGTCGACGTTGCCACGAACGCGCA
CGTGTCCGTGTTGGTGCTCGGCTGGCTGGTTGCAGTAATGATCCGCATCGCGACCGGCTCCGCCACCGTGGCCATGACCA
CGGCCGCCGGCATCGTCGCACCGATCGCGGCCAGCGTGCCGGGGACGCGCCCCGAACTGCTGGTGCTGACCACCGGCGCG
GGCTCGCTGATCTTGTCGCACGTGAATGACGGCGGCTTCTGGCTGGTCAAGGAGTACTTCAACATGACCGTGACCCAGAC
CTTCAAGACCTGGTCGGTCTGCGAAACCCTCATCTCGGTGGTAGCGCTGCTGCTCACGCTGGCACTGGCCACTGTCGTCT
GA

Upstream 100 bases:

>100_bases
GTCTGATTGCGCTTTCCCCGCCCGCGACCCGGGCGGGACATGAACTGAACTACAAACATTGCCGCCACAAGCGGCCTTTT
TTTCCACTCAAGGAGACAAC

Downstream 100 bases:

>100_bases
CCTGCGCTGAGCCGGCCAGGGCCCCCGTGTCAATCGGGATTGCCTTGGCCCGGGCACCCTCCTACACTCCCTCCTCGATG
CGGCCGCAAGTGCCGCACAG

Product: gluconate transporter

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVTGTTLLVYALIAVIALVILIARFKLNPFITLVVVSVLLGFAVGMPMGDIIKSFEAGVGGTLGHIALVVGLGTMLGK
MMAESGGAERIARTLIDFFGEKNVHWAMVTIAFIVGLPVFFEVGFVLLVPIAFNVAKRTGTSMVLVGIPMVAGLSVVHGL
IPPHPAALLAVTAYGADIGRTIMYALIVGIPTAAIAGPLFAKLMDRYVKLPDVNPLAAQFTEEDEKVKESHDLPGFGITV
FTILLPVLLMLIGSWADLFTTPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFNRDAILKFTNECVAPTAIITLVV
GAGGGFGRILRDSGISNAIVDVATNAHVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGA
GSLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVCETLISVVALLLTLALATVV

Sequences:

>Translated_453_residues
MGAVTGTTLLVYALIAVIALVILIARFKLNPFITLVVVSVLLGFAVGMPMGDIIKSFEAGVGGTLGHIALVVGLGTMLGK
MMAESGGAERIARTLIDFFGEKNVHWAMVTIAFIVGLPVFFEVGFVLLVPIAFNVAKRTGTSMVLVGIPMVAGLSVVHGL
IPPHPAALLAVTAYGADIGRTIMYALIVGIPTAAIAGPLFAKLMDRYVKLPDVNPLAAQFTEEDEKVKESHDLPGFGITV
FTILLPVLLMLIGSWADLFTTPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFNRDAILKFTNECVAPTAIITLVV
GAGGGFGRILRDSGISNAIVDVATNAHVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGA
GSLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVCETLISVVALLLTLALATVV
>Mature_452_residues
GAVTGTTLLVYALIAVIALVILIARFKLNPFITLVVVSVLLGFAVGMPMGDIIKSFEAGVGGTLGHIALVVGLGTMLGKM
MAESGGAERIARTLIDFFGEKNVHWAMVTIAFIVGLPVFFEVGFVLLVPIAFNVAKRTGTSMVLVGIPMVAGLSVVHGLI
PPHPAALLAVTAYGADIGRTIMYALIVGIPTAAIAGPLFAKLMDRYVKLPDVNPLAAQFTEEDEKVKESHDLPGFGITVF
TILLPVLLMLIGSWADLFTTPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFNRDAILKFTNECVAPTAIITLVVG
AGGGFGRILRDSGISNAIVDVATNAHVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGAG
SLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVCETLISVVALLLTLALATVV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=448, Percent_Identity=44.8660714285714, Blast_Score=355, Evalue=4e-99,
Organism=Escherichia coli, GI1790716, Length=435, Percent_Identity=43.2183908045977, Blast_Score=347, Evalue=7e-97,
Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=39.5505617977528, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI2367370, Length=431, Percent_Identity=39.4431554524362, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1790776, Length=438, Percent_Identity=34.4748858447489, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI48994939, Length=446, Percent_Identity=34.9775784753363, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1789097, Length=454, Percent_Identity=32.8193832599119, Blast_Score=226, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47466; Mature: 47335

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAVTGTTLLVYALIAVIALVILIARFKLNPFITLVVVSVLLGFAVGMPMGDIIKSFEAG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
VGGTLGHIALVVGLGTMLGKMMAESGGAERIARTLIDFFGEKNVHWAMVTIAFIVGLPVF
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FEVGFVLLVPIAFNVAKRTGTSMVLVGIPMVAGLSVVHGLIPPHPAALLAVTAYGADIGR
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHH
TIMYALIVGIPTAAIAGPLFAKLMDRYVKLPDVNPLAAQFTEEDEKVKESHDLPGFGITV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCHHHH
FTILLPVLLMLIGSWADLFTTPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFNRD
HHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AILKFTNECVAPTAIITLVVGAGGGFGRILRDSGISNAIVDVATNAHVSVLVLGWLVAVM
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHH
IRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGAGSLILSHVNDGGFWLVKEYF
HHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHH
NMTVTQTFKTWSVCETLISVVALLLTLALATVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA