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The map label for this gene is kdgR [H]

Identifier: 73537707

GI number: 73537707

Start: 490503

End: 491240

Strand: Reverse

Name: kdgR [H]

Synonym: Reut_B3872

Alternate gene names: 73537707

Gene position: 491240-490503 (Counterclockwise)

Preceding gene: 73537711

Following gene: 73537706

Centisome position: 18.02

GC content: 67.89

Gene sequence:

>738_bases
TTGCCCGTCCAGATCCCAGCAGCCAGCCGCGCCATGGCCGTATTCGAGGTCTTTGCGCGCGAAAAGCGCGACCTGTCCAA
TTCCGAGATGGCGAAGCTGCTTGCCGTGGCCGACAGCAGTTGCTCCGACCTGCTGCATACCCTGCATTCGCTCGGCTACC
TGATGCGCACCACGCGCACGCGGCGCTTTTACCCGACTGGCCGCCTGTTCGAGACCGCGCGCCAGATCGCGGAAAACGAC
CCGCTGACCCGGCTTGCGCAGGAAGCGGTGCAGCGCCTGACCGATGCCACCAACGAGAGCGCGTTCTTCGGCGTGCTGGA
ACCCCAGGCCGTGCGCGTTGCCGCTGTGGCGCAGAGCCGGCTGCCGCTGCGCTACATCCTTGATGTCGGCGAGCGTGTCG
CGCTGCACGCCTCCGCGCTGGGCAAGGCCCTGCTGGGCGTGCTGCCGGAGGGCGAGGCACGCAGCAGGCTGGAAGCCATC
CGCAGACCGGCCGTCACGCGCAGCACGGTGGTGGATATCGAGCCGCTGATGGCCCAACTCGCGCGTGGCCGCGAGCAAGG
CTGGTACGAAGCCCATGACGAAGGCACCGCGGGTGTGATGGCACTGGCGGTGCCGGCGCGTCTGGACGAGCGCCCGGTGG
CGATCTCGCTGGCCGGGCCCATCGAACGTATCGAAAAAAATCGCGAATCCTATCTGGCGGCCCTGCGCGATGTGCGCGAT
GGACTGCTGGCCGACTAG

Upstream 100 bases:

>100_bases
GATAAATACACCCCCTCGAAATATAGATTGCCTTGGTCTTCGACAGGTCGTACATTATTTCCAAATATCGTAAATACATA
CGGCATTTCGGAGATAGAGC

Downstream 100 bases:

>100_bases
TGATTTGCAAACCCGACTCTGCAAACCCCGACTCTGCAACCCATAAGGAGGAGAAATGGATCTTGGACTGAATGGCCGCG
TGGCGATCGTCACCGGCTCG

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPVQIPAASRAMAVFEVFAREKRDLSNSEMAKLLAVADSSCSDLLHTLHSLGYLMRTTRTRRFYPTGRLFETARQIAEND
PLTRLAQEAVQRLTDATNESAFFGVLEPQAVRVAAVAQSRLPLRYILDVGERVALHASALGKALLGVLPEGEARSRLEAI
RRPAVTRSTVVDIEPLMAQLARGREQGWYEAHDEGTAGVMALAVPARLDERPVAISLAGPIERIEKNRESYLAALRDVRD
GLLAD

Sequences:

>Translated_245_residues
MPVQIPAASRAMAVFEVFAREKRDLSNSEMAKLLAVADSSCSDLLHTLHSLGYLMRTTRTRRFYPTGRLFETARQIAEND
PLTRLAQEAVQRLTDATNESAFFGVLEPQAVRVAAVAQSRLPLRYILDVGERVALHASALGKALLGVLPEGEARSRLEAI
RRPAVTRSTVVDIEPLMAQLARGREQGWYEAHDEGTAGVMALAVPARLDERPVAISLAGPIERIEKNRESYLAALRDVRD
GLLAD
>Mature_244_residues
PVQIPAASRAMAVFEVFAREKRDLSNSEMAKLLAVADSSCSDLLHTLHSLGYLMRTTRTRRFYPTGRLFETARQIAENDP
LTRLAQEAVQRLTDATNESAFFGVLEPQAVRVAAVAQSRLPLRYILDVGERVALHASALGKALLGVLPEGEARSRLEAIR
RPAVTRSTVVDIEPLMAQLARGREQGWYEAHDEGTAGVMALAVPARLDERPVAISLAGPIERIEKNRESYLAALRDVRDG
LLAD

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=235, Percent_Identity=27.6595744680851, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788131, Length=238, Percent_Identity=27.3109243697479, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082359, Length=237, Percent_Identity=23.6286919831224, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26939; Mature: 26808

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQIPAASRAMAVFEVFAREKRDLSNSEMAKLLAVADSSCSDLLHTLHSLGYLMRTTRT
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
RRFYPTGRLFETARQIAENDPLTRLAQEAVQRLTDATNESAFFGVLEPQAVRVAAVAQSR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHC
LPLRYILDVGERVALHASALGKALLGVLPEGEARSRLEAIRRPAVTRSTVVDIEPLMAQL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGREQGWYEAHDEGTAGVMALAVPARLDERPVAISLAGPIERIEKNRESYLAALRDVRD
HCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GLLAD
HHCCC
>Mature Secondary Structure 
PVQIPAASRAMAVFEVFAREKRDLSNSEMAKLLAVADSSCSDLLHTLHSLGYLMRTTRT
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
RRFYPTGRLFETARQIAENDPLTRLAQEAVQRLTDATNESAFFGVLEPQAVRVAAVAQSR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHC
LPLRYILDVGERVALHASALGKALLGVLPEGEARSRLEAIRRPAVTRSTVVDIEPLMAQL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGREQGWYEAHDEGTAGVMALAVPARLDERPVAISLAGPIERIEKNRESYLAALRDVRD
HCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GLLAD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]