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The map label for this gene is bcd [H]

Identifier: 73537692

GI number: 73537692

Start: 473934

End: 475133

Strand: Direct

Name: bcd [H]

Synonym: Reut_B3857

Alternate gene names: 73537692

Gene position: 473934-475133 (Clockwise)

Preceding gene: 73537684

Following gene: 73537697

Centisome position: 17.38

GC content: 66.75

Gene sequence:

>1200_bases
ATGGACTTCCGACCCGACCCCAACCTCGCCGAGTTCCGCCAGCAGGTGCGTGACTTCCTGCGCGAACACATGCCGGCCGA
CATGCCGCGCCGCGCGCATGGCATGCGTTCGCCGCGCGATACGCTGATGCAGTGGCAGCGCGTGCTCAATACGCATGGCT
GGGGCGCGCCTTACTGGGCGGCCGAACACGGCGGCACGGGCTGGACCGTGGCACAGCGGCTGGCCTTCGACGAGGAGTGT
GCGCTGGCCGGAACGCCGTCGCAGGATGCCTTTGCGCAGAAACTTGTCGGGCCGGTGCTGAACCACTTCGGCACGCCGGC
GCAGAAGGACGAGCATGTCGGCGCCATCCTGCGCGGCGAGCGCCTGTGGTGCCAGGGCTTCTCCGAGCCGGGATCGGGTT
CGGACCTGGCGTCGCTGCGTACGCAGGCCGTGCGCGATGGCGACCACTACGTCATCAATGGCCAGAAGATCTGGACCAGC
TACGGCCACCAGGCCGACTGGATCTTCCTGCTGGTGCGTACCGGCAGCGGCGAGAAGAAGCAGGCCGGCATCACGTTCAT
CCTGGTGGACATGAAAACGCCCGGCATCACCGTGCGCCCGATCATCAGCATCGACGGCTGCCACCACCTGAACGAGACCT
TCTTCGACAACGTGCGCGTGCCCGTCGAAAACCTGATCGGCGAGGAAGGCGGCGGCTGGAAGATCACCAAGTTCCTGCTG
AACAACGAGCACGCGACCACGGCCGACCTGCCTACGCTGCGCCGCCTGCAACGCCAGCTCCGCGCATTCGCTGCAGCGCC
GGCCGCGGGCAGCACGCTGGGTGAGCAGCCCCAGTTCGCACTGCGGCTGGCGCGCTATGAGGCCGAGCTGGAAGCGATCG
CGGTCATGGTGCAGCGAGTCGCGGCGATGGAGCAAGCCGGTGACCACAGCCCGGCTGCGCACGCGTTGGGATCGATGCTG
AAGATCCGTGGTACCGAGCTGCAGCAGCAGATGGGGCAGTTTGCTGTGGAGAGCATGGGCGACTATGGTCCGGTGTCGTA
TCCGTCGAGCCACGATGGCCACGCCGGCGAGCCGCTGCCGATGCAGGACGTGATGCAGGATATTGCGACGGAGGCCTTCT
TCCGCCGTGCCACCACGATCTACGGCGGCACCAGCGAGATCCAGCGCGGCATCATCGCCAAGACGAAGTTCCGGCTCTGA

Upstream 100 bases:

>100_bases
CCAGTGGTGGGGGGCGCCGCGACCATCCCCAGCACTTAAGGTGTCACCATCCGGCAAGCCGCGTCCGCGGCGCCGCCACG
CCAGATGGAGAGCGAATCAG

Downstream 100 bases:

>100_bases
TCGCCACGCGGTAATCTGCGCCGTCCCTTGAATGGGACGGCGCGTTGGGCCTCTTACAGGCTGATCGCCTTCCACTCCAG
GAACTCGACCAGTCCTTCAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MDFRPDPNLAEFRQQVRDFLREHMPADMPRRAHGMRSPRDTLMQWQRVLNTHGWGAPYWAAEHGGTGWTVAQRLAFDEEC
ALAGTPSQDAFAQKLVGPVLNHFGTPAQKDEHVGAILRGERLWCQGFSEPGSGSDLASLRTQAVRDGDHYVINGQKIWTS
YGHQADWIFLLVRTGSGEKKQAGITFILVDMKTPGITVRPIISIDGCHHLNETFFDNVRVPVENLIGEEGGGWKITKFLL
NNEHATTADLPTLRRLQRQLRAFAAAPAAGSTLGEQPQFALRLARYEAELEAIAVMVQRVAAMEQAGDHSPAAHALGSML
KIRGTELQQQMGQFAVESMGDYGPVSYPSSHDGHAGEPLPMQDVMQDIATEAFFRRATTIYGGTSEIQRGIIAKTKFRL

Sequences:

>Translated_399_residues
MDFRPDPNLAEFRQQVRDFLREHMPADMPRRAHGMRSPRDTLMQWQRVLNTHGWGAPYWAAEHGGTGWTVAQRLAFDEEC
ALAGTPSQDAFAQKLVGPVLNHFGTPAQKDEHVGAILRGERLWCQGFSEPGSGSDLASLRTQAVRDGDHYVINGQKIWTS
YGHQADWIFLLVRTGSGEKKQAGITFILVDMKTPGITVRPIISIDGCHHLNETFFDNVRVPVENLIGEEGGGWKITKFLL
NNEHATTADLPTLRRLQRQLRAFAAAPAAGSTLGEQPQFALRLARYEAELEAIAVMVQRVAAMEQAGDHSPAAHALGSML
KIRGTELQQQMGQFAVESMGDYGPVSYPSSHDGHAGEPLPMQDVMQDIATEAFFRRATTIYGGTSEIQRGIIAKTKFRL
>Mature_399_residues
MDFRPDPNLAEFRQQVRDFLREHMPADMPRRAHGMRSPRDTLMQWQRVLNTHGWGAPYWAAEHGGTGWTVAQRLAFDEEC
ALAGTPSQDAFAQKLVGPVLNHFGTPAQKDEHVGAILRGERLWCQGFSEPGSGSDLASLRTQAVRDGDHYVINGQKIWTS
YGHQADWIFLLVRTGSGEKKQAGITFILVDMKTPGITVRPIISIDGCHHLNETFFDNVRVPVENLIGEEGGGWKITKFLL
NNEHATTADLPTLRRLQRQLRAFAAAPAAGSTLGEQPQFALRLARYEAELEAIAVMVQRVAAMEQAGDHSPAAHALGSML
KIRGTELQQQMGQFAVESMGDYGPVSYPSSHDGHAGEPLPMQDVMQDIATEAFFRRATTIYGGTSEIQRGIIAKTKFRL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=407, Percent_Identity=26.044226044226, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557231, Length=407, Percent_Identity=26.044226044226, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557235, Length=308, Percent_Identity=31.4935064935065, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI76496475, Length=404, Percent_Identity=28.7128712871287, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI7656849, Length=403, Percent_Identity=26.5508684863524, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI21361497, Length=385, Percent_Identity=26.4935064935065, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=310, Percent_Identity=28.0645161290323, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226958412, Length=397, Percent_Identity=23.9294710327456, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4501859, Length=352, Percent_Identity=28.4090909090909, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI226958414, Length=395, Percent_Identity=23.2911392405063, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4501857, Length=408, Percent_Identity=24.2647058823529, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI48976061, Length=313, Percent_Identity=24.2811501597444, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI211971008, Length=313, Percent_Identity=24.2811501597444, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786223, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=238, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=406, Percent_Identity=26.3546798029557, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=391, Percent_Identity=26.3427109974425, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=364, Percent_Identity=26.6483516483516, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=364, Percent_Identity=24.1758241758242, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=27.3584905660377, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=148, Percent_Identity=38.5135135135135, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=27.8089887640449, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=148, Percent_Identity=38.5135135135135, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=212, Percent_Identity=27.8301886792453, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=395, Percent_Identity=26.0759493670886, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=348, Percent_Identity=27.2988505747126, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=190, Percent_Identity=32.6315789473684, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=231, Percent_Identity=29.4372294372294, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=149, Percent_Identity=30.2013422818792, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531909, Length=260, Percent_Identity=26.5384615384615, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=398, Percent_Identity=27.8894472361809, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666513, Length=356, Percent_Identity=28.6516853932584, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363737, Length=149, Percent_Identity=36.241610738255, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21355753, Length=400, Percent_Identity=25.25, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=353, Percent_Identity=26.9121813031161, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=404, Percent_Identity=25.990099009901, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 44167; Mature: 44167

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRPDPNLAEFRQQVRDFLREHMPADMPRRAHGMRSPRDTLMQWQRVLNTHGWGAPYWA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
AEHGGTGWTVAQRLAFDEECALAGTPSQDAFAQKLVGPVLNHFGTPAQKDEHVGAILRGE
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
RLWCQGFSEPGSGSDLASLRTQAVRDGDHYVINGQKIWTSYGHQADWIFLLVRTGSGEKK
CCEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCEEEEEEECCCCCCC
QAGITFILVDMKTPGITVRPIISIDGCHHLNETFFDNVRVPVENLIGEEGGGWKITKFLL
CCCEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEE
NNEHATTADLPTLRRLQRQLRAFAAAPAAGSTLGEQPQFALRLARYEAELEAIAVMVQRV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAMEQAGDHSPAAHALGSMLKIRGTELQQQMGQFAVESMGDYGPVSYPSSHDGHAGEPLP
HHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
MQDVMQDIATEAFFRRATTIYGGTSEIQRGIIAKTKFRL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDFRPDPNLAEFRQQVRDFLREHMPADMPRRAHGMRSPRDTLMQWQRVLNTHGWGAPYWA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
AEHGGTGWTVAQRLAFDEECALAGTPSQDAFAQKLVGPVLNHFGTPAQKDEHVGAILRGE
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
RLWCQGFSEPGSGSDLASLRTQAVRDGDHYVINGQKIWTSYGHQADWIFLLVRTGSGEKK
CCEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCEEEEEEECCCCCCC
QAGITFILVDMKTPGITVRPIISIDGCHHLNETFFDNVRVPVENLIGEEGGGWKITKFLL
CCCEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEE
NNEHATTADLPTLRRLQRQLRAFAAAPAAGSTLGEQPQFALRLARYEAELEAIAVMVQRV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAMEQAGDHSPAAHALGSMLKIRGTELQQQMGQFAVESMGDYGPVSYPSSHDGHAGEPLP
HHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
MQDVMQDIATEAFFRRATTIYGGTSEIQRGIIAKTKFRL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]