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The map label for this gene is virS [H]

Identifier: 73537684

GI number: 73537684

Start: 464601

End: 465659

Strand: Direct

Name: virS [H]

Synonym: Reut_B3849

Alternate gene names: 73537684

Gene position: 464601-465659 (Clockwise)

Preceding gene: 73537683

Following gene: 73537692

Centisome position: 17.04

GC content: 66.67

Gene sequence:

>1059_bases
ATGAGCCGTTTAGTCCGCAGTGCCACGCTGTCCCGCTATACCGAGGTGGCCCGCTCGGTGGGGCTGGATCCATTGCGGAT
CCTGGCAGAAGTCGGGCTGCCCAGAACCTGCCTGGACGCCGGCGACAACCTGGTCTCCGCCAACGCGGTCTGCCGGCTGC
TCGAAATGTCCGCAGCCGATTCCGATGCCGAAGACTTCGGCCTGCGCATGGGGGAGGGCCGTCAATTGTCGGTACTGGGG
CCGCTCGGCATGGCAGTGCGGGACTCGCCGACGTTGCGCGATGCGCTGGGGGCGATGGTGCGCTATATCACGCTGCACAG
CGAGGCGCTGTTCCTCGGCGTGGAAGAACGCGAGGGCGCGCTTGTGATCCGCGTGTCGCTGATCGTGGAGCACGCCGGCT
CGACGCGCCAGGCCGACGAGATGGTCGTGGTGTCGCTTTACCGGATGCTTCAGGAACTGATCGGGCCAGGATGGCGCGCG
CGGCGGATCTGCCTTTCGCATGAGGCCCCAAGGAGCCTGGCATCCCATCTGCGCGTGTTCGGTCGGGCCGTCGATTTCGG
TTGCGACTTCAACGGCATCGTTTGCGAGCTGAAGGACATGGACGCCATGCCGCGCGCCGCGCGCCCGGAGCTGGCGCAGT
ACGCGCATGCCTATCTGGATTCACTGTCGGCGCGTGCGACCCTGTCCATGACCGAAAACGTCCGGCGGATGGTGCTGTCC
TTGCTCCCTTCGGGCAACTGCAGCGTGGAACGCGTCGCCAGCCAGCTTGGCGTCGACCGGCGCACGGTCCATCGCAAGCT
GCTGCAGGAAGGCGCGAGTTTCAGCAGCATTCTCGATGAGGTCCGTGCCACGCTGGCGCTGCAGTATCTGCGGCACTTGG
AGCGCCCGGTCAGCTACGTGGCCGTGTTGCTCGGGTTTTCGATGCAGAGCGCGTTCTCGCGCTGGTTCCGCGATCATTTT
GGCTGCAGCCCCAGCGCATGGCGCAGCGAGGGCATGCAGCCGGCGCGGCCCGTGCCGCGGCAACCTCTGCTAGCGGCGAG
CCCCGAGCAGCGCATGTAG

Upstream 100 bases:

>100_bases
GGCCCCAGCGCGCAGAGCTACAGCCTGATGCGCCGCGCCTGATTCCCGCGACAACCGAAGGCTGCAATGCCTTGCAGCCG
CCGCCCGTGCAAGGAGGCCC

Downstream 100 bases:

>100_bases
CACGGCGTTGCTCAGGCCATCTGCGGCCAGACAATGCGGTGCTCTGCTTCGATCGAGAGCGTTACGGCGGAGTCAGTATC
GATGAAGTTCGCTTCGTCCG

Product: Fis-type helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSRLVRSATLSRYTEVARSVGLDPLRILAEVGLPRTCLDAGDNLVSANAVCRLLEMSAADSDAEDFGLRMGEGRQLSVLG
PLGMAVRDSPTLRDALGAMVRYITLHSEALFLGVEEREGALVIRVSLIVEHAGSTRQADEMVVVSLYRMLQELIGPGWRA
RRICLSHEAPRSLASHLRVFGRAVDFGCDFNGIVCELKDMDAMPRAARPELAQYAHAYLDSLSARATLSMTENVRRMVLS
LLPSGNCSVERVASQLGVDRRTVHRKLLQEGASFSSILDEVRATLALQYLRHLERPVSYVAVLLGFSMQSAFSRWFRDHF
GCSPSAWRSEGMQPARPVPRQPLLAASPEQRM

Sequences:

>Translated_352_residues
MSRLVRSATLSRYTEVARSVGLDPLRILAEVGLPRTCLDAGDNLVSANAVCRLLEMSAADSDAEDFGLRMGEGRQLSVLG
PLGMAVRDSPTLRDALGAMVRYITLHSEALFLGVEEREGALVIRVSLIVEHAGSTRQADEMVVVSLYRMLQELIGPGWRA
RRICLSHEAPRSLASHLRVFGRAVDFGCDFNGIVCELKDMDAMPRAARPELAQYAHAYLDSLSARATLSMTENVRRMVLS
LLPSGNCSVERVASQLGVDRRTVHRKLLQEGASFSSILDEVRATLALQYLRHLERPVSYVAVLLGFSMQSAFSRWFRDHF
GCSPSAWRSEGMQPARPVPRQPLLAASPEQRM
>Mature_351_residues
SRLVRSATLSRYTEVARSVGLDPLRILAEVGLPRTCLDAGDNLVSANAVCRLLEMSAADSDAEDFGLRMGEGRQLSVLGP
LGMAVRDSPTLRDALGAMVRYITLHSEALFLGVEEREGALVIRVSLIVEHAGSTRQADEMVVVSLYRMLQELIGPGWRAR
RICLSHEAPRSLASHLRVFGRAVDFGCDFNGIVCELKDMDAMPRAARPELAQYAHAYLDSLSARATLSMTENVRRMVLSL
LPSGNCSVERVASQLGVDRRTVHRKLLQEGASFSSILDEVRATLALQYLRHLERPVSYVAVLLGFSMQSAFSRWFRDHFG
CSPSAWRSEGMQPARPVPRQPLLAASPEQRM

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38864; Mature: 38733

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVRSATLSRYTEVARSVGLDPLRILAEVGLPRTCLDAGDNLVSANAVCRLLEMSAAD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHCCC
SDAEDFGLRMGEGRQLSVLGPLGMAVRDSPTLRDALGAMVRYITLHSEALFLGVEEREGA
CCHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
LVIRVSLIVEHAGSTRQADEMVVVSLYRMLQELIGPGWRARRICLSHEAPRSLASHLRVF
EEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
GRAVDFGCDFNGIVCELKDMDAMPRAARPELAQYAHAYLDSLSARATLSMTENVRRMVLS
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPSGNCSVERVASQLGVDRRTVHRKLLQEGASFSSILDEVRATLALQYLRHLERPVSYV
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLLGFSMQSAFSRWFRDHFGCSPSAWRSEGMQPARPVPRQPLLAASPEQRM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLVRSATLSRYTEVARSVGLDPLRILAEVGLPRTCLDAGDNLVSANAVCRLLEMSAAD
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHCCC
SDAEDFGLRMGEGRQLSVLGPLGMAVRDSPTLRDALGAMVRYITLHSEALFLGVEEREGA
CCHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
LVIRVSLIVEHAGSTRQADEMVVVSLYRMLQELIGPGWRARRICLSHEAPRSLASHLRVF
EEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
GRAVDFGCDFNGIVCELKDMDAMPRAARPELAQYAHAYLDSLSARATLSMTENVRRMVLS
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPSGNCSVERVASQLGVDRRTVHRKLLQEGASFSSILDEVRATLALQYLRHLERPVSYV
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLLGFSMQSAFSRWFRDHFGCSPSAWRSEGMQPARPVPRQPLLAASPEQRM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]