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The map label for this gene is yngJ [H]

Identifier: 73537671

GI number: 73537671

Start: 449568

End: 450734

Strand: Direct

Name: yngJ [H]

Synonym: Reut_B3836

Alternate gene names: 73537671

Gene position: 449568-450734 (Clockwise)

Preceding gene: 73537670

Following gene: 73537672

Centisome position: 16.49

GC content: 67.69

Gene sequence:

>1167_bases
ATGAACTTCAATCTCACTTCCGAGCAGCAGATGCTGCAGGACAGCGTGGCCCGCTTCGTCGAGAAGGACTATGACTTCGA
GGCTCGCACCGCGCTGGTCAAGGCCGGTTCGCGCTGCGACGCGAAGCACTGGAATACCTTCGCCAACAACGGCTGGCTTG
CCGCCGCGCTGCCGGAAGAGCAGGGCGGCCTCGGCGGTACGCTGCTCGACACCGTGCTGATCGCGGGCCAGCTCGGCCGC
GGCCTCGTCATCGAGCCGTACCTCGGCTGCGCAGTCGCTGCCGCACAGACGCTGCTGGCCGCCGCCACGCCCGCCCAGCG
CGATGCGCTGCTACCGGCCGTGGCGGAAGGCTCGCGCAAGATTGCGCTGGCGTACAGCGAAGCCGGCTCCCGCGGCCTGC
CCGCGCCGGTATCCACGCATGCCGACGCCGCGCCGGGCGGCTACGTGCTGAACGGCGTCAAGACCCTCGTGCTCGGCGGC
ACCGAAGCCGACGCGTTCATCGTCTCGGCCATGACGCCGATCGCCGAGCCGGCCAGCGCCCATGATGGTGGCGAACTGCG
CCTGTTCGTGGTGGACGCCGATGCACCGGGCGTCAAGCGCCGCGCCCTGCCGCTGCATGACGGTACGTGGGCTGCTGAAG
TGACGTTCGACGGCGTTGCCGTCAAGGCTGATGCCCTGCTCGGCGAGCCGGGAACCGGTCTGGCCGCACTGCAGCAGGGC
CTGCTGCACGGAACCACCGCCTTGTGCGCGGAAATCGTAGGCGCGATGGAAAAGACCATCGAGATCACGTCCGAATACCT
GAAGGTGCGCCAGCAGTTCGGCGTTCCCATCGGCAGCTTCCAGGCCCTGCAGCATCGCATGGCCGACATGGCCGCCGAAA
TGGAAGTCGCGCGCTCGATGCTGTACGCGCTGCTGGCCGCCGTCGAAACCGGCACGCCGGAAACGGTGCAACGCACGATG
TCGCAGGCCAAGGCCCTGATTGGCCGCGCCGCCAAGTACGTATGCGGCCAGGGTATCCAGCTGCACGGCGGCATCGGCAT
GACCGAGGAATACACGGTCGGTCACTACTTCAAGCGCGCGGTGGTAGCCGATGCGCTCTTCGGCAACGCCGACCTGCATG
AATCGCTGGTCGCCCAGGCGTTGCAGCAATCCCTGACCACGGAGTGA

Upstream 100 bases:

>100_bases
ACCATTTACGGCGGCACCAGCGAAGTCCAGCGCGGCATCATCGCCCGCGCCCTGTTCCAACTCTGACGCCGCGACGCGCG
TCTCCTGGCACATAACGATC

Downstream 100 bases:

>100_bases
GAACGAGCATGAAAGTCTACGAAAAGATCAGCGACCTGCAGCCTCTGGTGGGCGAAATCATCGGTACGAGCGATTGGGTG
AGTGTCGAGCAAGGCCGTAT

Product: acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNFNLTSEQQMLQDSVARFVEKDYDFEARTALVKAGSRCDAKHWNTFANNGWLAAALPEEQGGLGGTLLDTVLIAGQLGR
GLVIEPYLGCAVAAAQTLLAAATPAQRDALLPAVAEGSRKIALAYSEAGSRGLPAPVSTHADAAPGGYVLNGVKTLVLGG
TEADAFIVSAMTPIAEPASAHDGGELRLFVVDADAPGVKRRALPLHDGTWAAEVTFDGVAVKADALLGEPGTGLAALQQG
LLHGTTALCAEIVGAMEKTIEITSEYLKVRQQFGVPIGSFQALQHRMADMAAEMEVARSMLYALLAAVETGTPETVQRTM
SQAKALIGRAAKYVCGQGIQLHGGIGMTEEYTVGHYFKRAVVADALFGNADLHESLVAQALQQSLTTE

Sequences:

>Translated_388_residues
MNFNLTSEQQMLQDSVARFVEKDYDFEARTALVKAGSRCDAKHWNTFANNGWLAAALPEEQGGLGGTLLDTVLIAGQLGR
GLVIEPYLGCAVAAAQTLLAAATPAQRDALLPAVAEGSRKIALAYSEAGSRGLPAPVSTHADAAPGGYVLNGVKTLVLGG
TEADAFIVSAMTPIAEPASAHDGGELRLFVVDADAPGVKRRALPLHDGTWAAEVTFDGVAVKADALLGEPGTGLAALQQG
LLHGTTALCAEIVGAMEKTIEITSEYLKVRQQFGVPIGSFQALQHRMADMAAEMEVARSMLYALLAAVETGTPETVQRTM
SQAKALIGRAAKYVCGQGIQLHGGIGMTEEYTVGHYFKRAVVADALFGNADLHESLVAQALQQSLTTE
>Mature_388_residues
MNFNLTSEQQMLQDSVARFVEKDYDFEARTALVKAGSRCDAKHWNTFANNGWLAAALPEEQGGLGGTLLDTVLIAGQLGR
GLVIEPYLGCAVAAAQTLLAAATPAQRDALLPAVAEGSRKIALAYSEAGSRGLPAPVSTHADAAPGGYVLNGVKTLVLGG
TEADAFIVSAMTPIAEPASAHDGGELRLFVVDADAPGVKRRALPLHDGTWAAEVTFDGVAVKADALLGEPGTGLAALQQG
LLHGTTALCAEIVGAMEKTIEITSEYLKVRQQFGVPIGSFQALQHRMADMAAEMEVARSMLYALLAAVETGTPETVQRTM
SQAKALIGRAAKYVCGQGIQLHGGIGMTEEYTVGHYFKRAVVADALFGNADLHESLVAQALQQSLTTE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=385, Percent_Identity=26.2337662337662, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4501859, Length=387, Percent_Identity=25.8397932816537, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=28.7179487179487, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=28.7179487179487, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=27.1676300578035, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7656849, Length=327, Percent_Identity=27.217125382263, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557233, Length=398, Percent_Identity=25.6281407035176, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4501857, Length=385, Percent_Identity=23.3766233766234, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI21361497, Length=346, Percent_Identity=26.0115606936416, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4557231, Length=396, Percent_Identity=22.7272727272727, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI187960098, Length=396, Percent_Identity=22.7272727272727, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4503943, Length=298, Percent_Identity=25.1677852348993, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI7669494, Length=270, Percent_Identity=26.2962962962963, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=25.7294429708223, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=24.3386243386243, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=392, Percent_Identity=25.765306122449, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17506239, Length=340, Percent_Identity=26.1764705882353, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=397, Percent_Identity=26.448362720403, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=342, Percent_Identity=26.6081871345029, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=259, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=393, Percent_Identity=24.4274809160305, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=24.3654822335025, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=290, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=27.9166666666667, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=330, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=239, Percent_Identity=25.9414225941423, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=322, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=322, Percent_Identity=25.776397515528, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=397, Percent_Identity=25.9445843828715, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21355753, Length=391, Percent_Identity=26.8542199488491, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356377, Length=399, Percent_Identity=27.5689223057644, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281363737, Length=371, Percent_Identity=26.9541778975741, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646207, Length=289, Percent_Identity=25.2595155709343, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24660351, Length=400, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 40615; Mature: 40615

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNLTSEQQMLQDSVARFVEKDYDFEARTALVKAGSRCDAKHWNTFANNGWLAAALPEE
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCC
QGGLGGTLLDTVLIAGQLGRGLVIEPYLGCAVAAAQTLLAAATPAQRDALLPAVAEGSRK
CCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCE
IALAYSEAGSRGLPAPVSTHADAAPGGYVLNGVKTLVLGGTEADAFIVSAMTPIAEPASA
EEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHCCCCCCCCC
HDGGELRLFVVDADAPGVKRRALPLHDGTWAAEVTFDGVAVKADALLGEPGTGLAALQQG
CCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHCCCCCCCHHHHHHH
LLHGTTALCAEIVGAMEKTIEITSEYLKVRQQFGVPIGSFQALQHRMADMAAEMEVARSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYALLAAVETGTPETVQRTMSQAKALIGRAAKYVCGQGIQLHGGIGMTEEYTVGHYFKRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHH
VVADALFGNADLHESLVAQALQQSLTTE
HHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFNLTSEQQMLQDSVARFVEKDYDFEARTALVKAGSRCDAKHWNTFANNGWLAAALPEE
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCC
QGGLGGTLLDTVLIAGQLGRGLVIEPYLGCAVAAAQTLLAAATPAQRDALLPAVAEGSRK
CCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCE
IALAYSEAGSRGLPAPVSTHADAAPGGYVLNGVKTLVLGGTEADAFIVSAMTPIAEPASA
EEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHCCCCCCCCC
HDGGELRLFVVDADAPGVKRRALPLHDGTWAAEVTFDGVAVKADALLGEPGTGLAALQQG
CCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHCCCCCCCHHHHHHH
LLHGTTALCAEIVGAMEKTIEITSEYLKVRQQFGVPIGSFQALQHRMADMAAEMEVARSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYALLAAVETGTPETVQRTMSQAKALIGRAAKYVCGQGIQLHGGIGMTEEYTVGHYFKRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHH
VVADALFGNADLHESLVAQALQQSLTTE
HHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]