Click here to switch to the map view.

The map label for this gene is ydiO [H]

Identifier: 73537545

GI number: 73537545

Start: 297733

End: 298890

Strand: Direct

Name: ydiO [H]

Synonym: Reut_B3710

Alternate gene names: 73537545

Gene position: 297733-298890 (Clockwise)

Preceding gene: 73537544

Following gene: 73537546

Centisome position: 10.92

GC content: 69.86

Gene sequence:

>1158_bases
ATGAGCGATTCCCACGACGACCGCCGCATGCTGCGGGAAAGCGTACGGCGCTATGTCGAACGCGACTATGGCTTTGAACA
GCGCCGCGCGGCGCTGGCGGAGCCGGGCGGCTTCTCGCGCAGGCACTGGCAGGCATTTGCCGAGTTCGGCTGGCTGGCGC
TCGGCCTGCCCGACGCCTGTGCCGGGTTTGGCGATGCATCGGACCAGGCCGTATTGGCCGAGGCGCTCGGATGTGCTCAA
CCCGCCGAGCCGTGGCTGGCCAATGCCGCCTTGTGCGGCCCGCTGCTGGCCGCTTGCGGCGACGCTGCACATGCCGTCAC
CGCAGCCGCGATGGCGGAGGGCAGGACGATGCTGGCGCTGGCCGCATGGGAGGCGCAAGGGCGTTATGACGCCTTCGATG
TCGCTACGTCTGCAGAGCCACGGCAAAGCGCAGGCCCCATCGACTGGATGCTGGATGGGCGCAAGACGCTGGTGCTCGGC
GGCGGCTGTGCCGACATCCTGCTCGTACTGGCGCGCAACAGCGGCCAGCGCCGCGACCGCGATGGCCTCACGCTGTTCGC
CGTGCCAGCCGGCACACGCGGCGTCGCCATCGAGGCATTGCCGACATATGACGGCCGCCAGACCGCCACGGTCACGCTGC
GGCGTGTGAGCGTTCCCGACAGCGCGCGAGTCGGTGCCGTCGGCGGTGCGTGGCCGAGCGTCGAAGCCGCTATCGATCGC
GCCACTACCATGGCCTGCGCGGAAGCCGTGGGCACCATGGCGCGCGCGTTCGAGCTGACGCGCGATTACCTCGTTACGCG
TGAGCAGTTCGGCCGGCCGCTGTCCGCCAACCAGGTGATCCGCCACCGGCTGGTCGACCTCTATGTCAGCGTGGAACAGG
CGCGTGCCATCACCGAAGCGGCCGCCGCTGCGCTGCAGGGCGATGCGGCAGCGCGGATGCGTGCGGTCTCGCTCGCCAAG
GCCTTCGTCTCGGTCGCGGGACGCGCGCTCGGCGAAGACGCGGTGCAGCTGCACGGCGCGGTCGGCATGACCGATGAGAT
GGAAGTTGGCCACTGCTACAAGCGGCTCGCCGCGCTGGCCAACCTGTTCGGCGATGCCGACTGGCACTACGAACGGCTTT
CTGCCGTCGATCCCGCGGATCAGGCGCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GTGGCTACACCATCGCTGGCGGCTCCAGCGAGATCCAGCACGAACTGCTGGCCAAGCAAGTGCTCGGGCTCTAACAAACT
CTGCGAAAGGAACGGAACCC

Downstream 100 bases:

>100_bases
GCCGCATTACCCGGGGCGCCTGCGAGCGCCCATACACAACACGCCGGCAACGCACCGGCATGGGCGGCCAATGCGCCGCA
ATGGAGACCACATCATGTTC

Product: acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSDSHDDRRMLRESVRRYVERDYGFEQRRAALAEPGGFSRRHWQAFAEFGWLALGLPDACAGFGDASDQAVLAEALGCAQ
PAEPWLANAALCGPLLAACGDAAHAVTAAAMAEGRTMLALAAWEAQGRYDAFDVATSAEPRQSAGPIDWMLDGRKTLVLG
GGCADILLVLARNSGQRRDRDGLTLFAVPAGTRGVAIEALPTYDGRQTATVTLRRVSVPDSARVGAVGGAWPSVEAAIDR
ATTMACAEAVGTMARAFELTRDYLVTREQFGRPLSANQVIRHRLVDLYVSVEQARAITEAAAAALQGDAAARMRAVSLAK
AFVSVAGRALGEDAVQLHGAVGMTDEMEVGHCYKRLAALANLFGDADWHYERLSAVDPADQALAA

Sequences:

>Translated_385_residues
MSDSHDDRRMLRESVRRYVERDYGFEQRRAALAEPGGFSRRHWQAFAEFGWLALGLPDACAGFGDASDQAVLAEALGCAQ
PAEPWLANAALCGPLLAACGDAAHAVTAAAMAEGRTMLALAAWEAQGRYDAFDVATSAEPRQSAGPIDWMLDGRKTLVLG
GGCADILLVLARNSGQRRDRDGLTLFAVPAGTRGVAIEALPTYDGRQTATVTLRRVSVPDSARVGAVGGAWPSVEAAIDR
ATTMACAEAVGTMARAFELTRDYLVTREQFGRPLSANQVIRHRLVDLYVSVEQARAITEAAAAALQGDAAARMRAVSLAK
AFVSVAGRALGEDAVQLHGAVGMTDEMEVGHCYKRLAALANLFGDADWHYERLSAVDPADQALAA
>Mature_384_residues
SDSHDDRRMLRESVRRYVERDYGFEQRRAALAEPGGFSRRHWQAFAEFGWLALGLPDACAGFGDASDQAVLAEALGCAQP
AEPWLANAALCGPLLAACGDAAHAVTAAAMAEGRTMLALAAWEAQGRYDAFDVATSAEPRQSAGPIDWMLDGRKTLVLGG
GCADILLVLARNSGQRRDRDGLTLFAVPAGTRGVAIEALPTYDGRQTATVTLRRVSVPDSARVGAVGGAWPSVEAAIDRA
TTMACAEAVGTMARAFELTRDYLVTREQFGRPLSANQVIRHRLVDLYVSVEQARAITEAAAAALQGDAAARMRAVSLAKA
FVSVAGRALGEDAVQLHGAVGMTDEMEVGHCYKRLAALANLFGDADWHYERLSAVDPADQALAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=324, Percent_Identity=26.8518518518519, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4557231, Length=324, Percent_Identity=26.8518518518519, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI7656849, Length=223, Percent_Identity=27.8026905829596, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4501857, Length=365, Percent_Identity=23.013698630137, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557233, Length=356, Percent_Identity=23.5955056179775, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=25.561797752809, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=305, Percent_Identity=25.2459016393443, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=318, Percent_Identity=25.7861635220126, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=313, Percent_Identity=24.9201277955272, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=328, Percent_Identity=24.0853658536585, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=312, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=22.8882833787466, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=23.5457063711911, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=22.0994475138122, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 40887; Mature: 40756

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSHDDRRMLRESVRRYVERDYGFEQRRAALAEPGGFSRRHWQAFAEFGWLALGLPDAC
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCHHH
AGFGDASDQAVLAEALGCAQPAEPWLANAALCGPLLAACGDAAHAVTAAAMAEGRTMLAL
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
AAWEAQGRYDAFDVATSAEPRQSAGPIDWMLDGRKTLVLGGGCADILLVLARNSGQRRDR
EEECCCCCCCHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHCCCCCCCCC
DGLTLFAVPAGTRGVAIEALPTYDGRQTATVTLRRVSVPDSARVGAVGGAWPSVEAAIDR
CCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
ATTMACAEAVGTMARAFELTRDYLVTREQFGRPLSANQVIRHRLVDLYVSVEQARAITEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAAALQGDAAARMRAVSLAKAFVSVAGRALGEDAVQLHGAVGMTDEMEVGHCYKRLAALA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
NLFGDADWHYERLSAVDPADQALAA
HHHCCCCHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SDSHDDRRMLRESVRRYVERDYGFEQRRAALAEPGGFSRRHWQAFAEFGWLALGLPDAC
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCHHH
AGFGDASDQAVLAEALGCAQPAEPWLANAALCGPLLAACGDAAHAVTAAAMAEGRTMLAL
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
AAWEAQGRYDAFDVATSAEPRQSAGPIDWMLDGRKTLVLGGGCADILLVLARNSGQRRDR
EEECCCCCCCHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHCCCCCCCCC
DGLTLFAVPAGTRGVAIEALPTYDGRQTATVTLRRVSVPDSARVGAVGGAWPSVEAAIDR
CCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
ATTMACAEAVGTMARAFELTRDYLVTREQFGRPLSANQVIRHRLVDLYVSVEQARAITEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAAALQGDAAARMRAVSLAKAFVSVAGRALGEDAVQLHGAVGMTDEMEVGHCYKRLAALA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
NLFGDADWHYERLSAVDPADQALAA
HHHCCCCHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]