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The map label for this gene is bcd [H]

Identifier: 73537544

GI number: 73537544

Start: 296483

End: 297706

Strand: Direct

Name: bcd [H]

Synonym: Reut_B3709

Alternate gene names: 73537544

Gene position: 296483-297706 (Clockwise)

Preceding gene: 73537543

Following gene: 73537545

Centisome position: 10.88

GC content: 67.89

Gene sequence:

>1224_bases
ATGAGTGAATCCATCACGACTGACAGCGAAGCCTCCCTGGAGGCATTCCGCCGCGAGGTCCGCGACTTTGTTGCGCAGGC
CTTGCCGGAAATCGTGCGCGAGAAGGTGCGCCTGGGCCTTGAGGTCAGCAAGGACGAAATGGTCGCCTGGCAGCACCGGC
TGGCCGAACGCGGCTGGCTGGCGCCGCACTGGCCGCGCGACTGGCAGGGCCTAGGCTGGAGCGCCGAGCGGCGCGCCGTG
TTCCAGGAGGAACTGGTGCTCGCCCACGCGCCGGAGACCGGTGGCATCTCGATCGAGATGATCGGGCCGATTCTGATCCG
CTACGGCACGCCGGCGCAGCAGCAGTATTTCCTGCCGCGCATCCTTAATCTGGAGCACTGGTGGTGCCAGGGGTATTCGG
AGCCCAACGCGGGGTCGGACCTCGCATCGCTGAAGACGCATGCGGTGCGCAAGACGCGCGCCGACGGCACCGAAGTCTAT
GTCGTCAATGGCAGCAAGATCTGGACGTCGTACGCGCAGTACGCGGACTGGATCTTCTGCCTGGTGCGGACTGACAGCGC
GGCGCGCGCGCAGCAGGGCATCAGCTTCCTGCTGATCGATATGCGCAGCCCCGGCATCAGCGTGCGGCCGCTCGTAGGCA
TCCACGGCTGGCACCTGTTCAACCAGGTGTTCTTCGACGATGTCGAGGTGCCCGTCGACCACCGCGTCGGCGACGAGAAC
GCGGGCTGGACGATCGCCAAGTCGCTGCTCGAGCATGAGCGGCTGAACCTCGCCCGCGTGGCCGAGAACCGGCGCCGGCT
GGTCAAGGTGCGCGCCATTGCCGCGGAAGTCGAAGAAGCCGGACAGCCGCTGATGGAACGGCCGTGGTTTGCGCGCCGCT
ATCGTGAACTCGACGTGCGACTGGAAGCGCTGGCCGCGACCGTGCTGCGCTTTCGGCAGCGGGCGCGTGCGGGCGAGCGG
CTCGGTCCCGAGACCGGCATGCTCAAGCTGCTCGGCAGCCGCCTGATCCAGGACATCGAGAACCTCGCCGTCGACGCGCT
CGGCCCCGGCACGCTCGCCTACGACCGCGCGGCGCACTTCGAGCCGGCGGCGCCACGCTCCGGGCAATCCGCGTACTCGG
CAGCCGCTTCCGCGAGGCGCTTCGTGACGCGTGGCTACACCATCGCTGGCGGCTCCAGCGAGATCCAGCACGAACTGCTG
GCCAAGCAAGTGCTCGGGCTCTAA

Upstream 100 bases:

>100_bases
GCCGCTTTCCCGGCCGGCGGCGTGACCGCGATCAAGCGTGGCATGCGTGCCGCCAGCACGCGCATGGCGCGCGATACCCA
CGACTGAAGCGAGATCCCGC

Downstream 100 bases:

>100_bases
CAAACTCTGCGAAAGGAACGGAACCCATGAGCGATTCCCACGACGACCGCCGCATGCTGCGGGAAAGCGTACGGCGCTAT
GTCGAACGCGACTATGGCTT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSESITTDSEASLEAFRREVRDFVAQALPEIVREKVRLGLEVSKDEMVAWQHRLAERGWLAPHWPRDWQGLGWSAERRAV
FQEELVLAHAPETGGISIEMIGPILIRYGTPAQQQYFLPRILNLEHWWCQGYSEPNAGSDLASLKTHAVRKTRADGTEVY
VVNGSKIWTSYAQYADWIFCLVRTDSAARAQQGISFLLIDMRSPGISVRPLVGIHGWHLFNQVFFDDVEVPVDHRVGDEN
AGWTIAKSLLEHERLNLARVAENRRRLVKVRAIAAEVEEAGQPLMERPWFARRYRELDVRLEALAATVLRFRQRARAGER
LGPETGMLKLLGSRLIQDIENLAVDALGPGTLAYDRAAHFEPAAPRSGQSAYSAAASARRFVTRGYTIAGGSSEIQHELL
AKQVLGL

Sequences:

>Translated_407_residues
MSESITTDSEASLEAFRREVRDFVAQALPEIVREKVRLGLEVSKDEMVAWQHRLAERGWLAPHWPRDWQGLGWSAERRAV
FQEELVLAHAPETGGISIEMIGPILIRYGTPAQQQYFLPRILNLEHWWCQGYSEPNAGSDLASLKTHAVRKTRADGTEVY
VVNGSKIWTSYAQYADWIFCLVRTDSAARAQQGISFLLIDMRSPGISVRPLVGIHGWHLFNQVFFDDVEVPVDHRVGDEN
AGWTIAKSLLEHERLNLARVAENRRRLVKVRAIAAEVEEAGQPLMERPWFARRYRELDVRLEALAATVLRFRQRARAGER
LGPETGMLKLLGSRLIQDIENLAVDALGPGTLAYDRAAHFEPAAPRSGQSAYSAAASARRFVTRGYTIAGGSSEIQHELL
AKQVLGL
>Mature_406_residues
SESITTDSEASLEAFRREVRDFVAQALPEIVREKVRLGLEVSKDEMVAWQHRLAERGWLAPHWPRDWQGLGWSAERRAVF
QEELVLAHAPETGGISIEMIGPILIRYGTPAQQQYFLPRILNLEHWWCQGYSEPNAGSDLASLKTHAVRKTRADGTEVYV
VNGSKIWTSYAQYADWIFCLVRTDSAARAQQGISFLLIDMRSPGISVRPLVGIHGWHLFNQVFFDDVEVPVDHRVGDENA
GWTIAKSLLEHERLNLARVAENRRRLVKVRAIAAEVEEAGQPLMERPWFARRYRELDVRLEALAATVLRFRQRARAGERL
GPETGMLKLLGSRLIQDIENLAVDALGPGTLAYDRAAHFEPAAPRSGQSAYSAAASARRFVTRGYTIAGGSSEIQHELLA
KQVLGL

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=261, Percent_Identity=27.9693486590038, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI226958414, Length=211, Percent_Identity=29.8578199052133, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7656849, Length=307, Percent_Identity=26.3843648208469, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4557231, Length=301, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187960098, Length=301, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI76496475, Length=305, Percent_Identity=27.5409836065574, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4557235, Length=305, Percent_Identity=27.5409836065574, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4557233, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI21361497, Length=261, Percent_Identity=24.1379310344828, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4501857, Length=273, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI211971008, Length=292, Percent_Identity=25.6849315068493, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48976061, Length=292, Percent_Identity=25.6849315068493, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=279, Percent_Identity=25.089605734767, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=252, Percent_Identity=26.5873015873016, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=214, Percent_Identity=30.3738317757009, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=208, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=268, Percent_Identity=27.2388059701493, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=305, Percent_Identity=25.5737704918033, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=208, Percent_Identity=26.4423076923077, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=216, Percent_Identity=28.2407407407407, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=216, Percent_Identity=28.2407407407407, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355753, Length=267, Percent_Identity=28.8389513108614, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363737, Length=282, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24666513, Length=208, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24660351, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 45766; Mature: 45634

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESITTDSEASLEAFRREVRDFVAQALPEIVREKVRLGLEVSKDEMVAWQHRLAERGWL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
APHWPRDWQGLGWSAERRAVFQEELVLAHAPETGGISIEMIGPILIRYGTPAQQQYFLPR
CCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEECCCCEECCCCHHHHHHHHH
ILNLEHWWCQGYSEPNAGSDLASLKTHAVRKTRADGTEVYVVNGSKIWTSYAQYADWIFC
HHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHEEE
LVRTDSAARAQQGISFLLIDMRSPGISVRPLVGIHGWHLFNQVFFDDVEVPVDHRVGDEN
EEECCCHHHHHCCCEEEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AGWTIAKSLLEHERLNLARVAENRRRLVKVRAIAAEVEEAGQPLMERPWFARRYRELDVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHH
LEALAATVLRFRQRARAGERLGPETGMLKLLGSRLIQDIENLAVDALGPGTLAYDRAAHF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
EPAAPRSGQSAYSAAASARRFVTRGYTIAGGSSEIQHELLAKQVLGL
CCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SESITTDSEASLEAFRREVRDFVAQALPEIVREKVRLGLEVSKDEMVAWQHRLAERGWL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
APHWPRDWQGLGWSAERRAVFQEELVLAHAPETGGISIEMIGPILIRYGTPAQQQYFLPR
CCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEECCCCEECCCCHHHHHHHHH
ILNLEHWWCQGYSEPNAGSDLASLKTHAVRKTRADGTEVYVVNGSKIWTSYAQYADWIFC
HHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHEEE
LVRTDSAARAQQGISFLLIDMRSPGISVRPLVGIHGWHLFNQVFFDDVEVPVDHRVGDEN
EEECCCHHHHHCCCEEEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AGWTIAKSLLEHERLNLARVAENRRRLVKVRAIAAEVEEAGQPLMERPWFARRYRELDVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHH
LEALAATVLRFRQRARAGERLGPETGMLKLLGSRLIQDIENLAVDALGPGTLAYDRAAHF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
EPAAPRSGQSAYSAAASARRFVTRGYTIAGGSSEIQHELLAKQVLGL
CCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]