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The map label for this gene is mmgC [H]

Identifier: 73537387

GI number: 73537387

Start: 102676

End: 103866

Strand: Direct

Name: mmgC [H]

Synonym: Reut_B3552

Alternate gene names: 73537387

Gene position: 102676-103866 (Clockwise)

Preceding gene: 73537386

Following gene: 73537388

Centisome position: 3.77

GC content: 62.05

Gene sequence:

>1191_bases
ATGGGATCTCCCGAACTGAATGCCACCGCCGCTGCCTCCACCGAGGCCCCCTGGATGACCGAAGACCTGGTCCTGTTCCG
GGACACGGTGCGGCGCTTTGTCGAACGTGAACTGGCGCCGAACGAATCGCGCTGGGCCGAGCAGGGCTATATCGACCGCG
ACGTCTGGCGCCGTGCCGGCCAGATCGGCCTGCTGTGCGCGAGCATCCCCGAGGAATACGGCGGCGGTGGTGGCACCTTT
GCGCACGAGGCCGTCATCACGCAGGAAATGGCGCGCGGCATCTGCACCAGCCTGGGCAATAACGTGCATAGCGGCATCGT
GGCCCACTACTTGCTCAACTACGGCACACAGGCGCAGAAGGAGAAATGGCTGCCACAGATGGCCAGCGGCGAAATGGTGG
CGGCGATCGCCATGTCGGAACCAGGTGCCGGCTCGGACCTCAAATCGGTACGCACCCGCGCGGTGCGCGAGAAGACAGAA
AACGGGGATTGCTATCGCATCAACGGTGCAAAGACTTTCATTACCAACGGCTATCACGCCGACTTGGTCTGCCTGATTGC
GAAGACCGATCCGGAAGCCGGCACGCGCGGGGTGTCGCTGATCATGGTGGAGACCCGTGATCTGCCGGGGTTCCGTCGCG
GCCGCATCCTGGAGAAGATCGGACAGAAAGGCCAGGATACTGCCGAGCTGTTCTTCGACGACGTGCTGGTACCTTGCGAG
AACCTGCTCGGCGAGCAGGAGGGGCAAGGCTTCTACCAGCTCATGCAGCAGTTGCCGCAGGAGCGGATGATCATCGCCCT
TGGTGCGGTGGCGAGCATGCAGCGCGCCATCGAGCTGACGACCGACTATGTGCGCGAGCGCAAGGTGTTCGGTCAACCGT
TGCTCGACTTGCAGAACACGCGTTTCAAACTGGCTGAGTGCAAGACCAATGCGACCATCGCGGCCACGTTCGTGAACGAC
TGCATGGTGCGGCTGATGGAAGGCAAGCTCGACGCAGCGACCGCGGCAATGGCCAAGTGGTGGTGCACGCAACGCAACTG
CGAAATCATCGACGAGTGCCTGCAGTTGCATGGCGGCTACGGCTATATGCTCGAATACCCGATTGCACGCATGTACGCGA
ATGCGCGTGTCGGCAAGATCTACGGTGGCTCGAACGAGATCATGAAAGAGCTGGTCGCACGCACGCTCTGA

Upstream 100 bases:

>100_bases
CGCAAGGCTTCAACGAAATACGCCTATCTATATAGAGGCGCGACAGCGGTAATGCCGCCTGTCCTCCTTTTCCCTCTGCA
TTTCGAAGTCGATACACATC

Downstream 100 bases:

>100_bases
GTGCTGTCATCAGCAGTCGGCGTGTGCTGATGCACGCCGCGAAAACCTCAGCAAAAGGCCGGCGAAATCGCTGGCCTTTT
TTGTGTACTGGTTACAAAAC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGSPELNATAAASTEAPWMTEDLVLFRDTVRRFVERELAPNESRWAEQGYIDRDVWRRAGQIGLLCASIPEEYGGGGGTF
AHEAVITQEMARGICTSLGNNVHSGIVAHYLLNYGTQAQKEKWLPQMASGEMVAAIAMSEPGAGSDLKSVRTRAVREKTE
NGDCYRINGAKTFITNGYHADLVCLIAKTDPEAGTRGVSLIMVETRDLPGFRRGRILEKIGQKGQDTAELFFDDVLVPCE
NLLGEQEGQGFYQLMQQLPQERMIIALGAVASMQRAIELTTDYVRERKVFGQPLLDLQNTRFKLAECKTNATIAATFVND
CMVRLMEGKLDAATAAMAKWWCTQRNCEIIDECLQLHGGYGYMLEYPIARMYANARVGKIYGGSNEIMKELVARTL

Sequences:

>Translated_396_residues
MGSPELNATAAASTEAPWMTEDLVLFRDTVRRFVERELAPNESRWAEQGYIDRDVWRRAGQIGLLCASIPEEYGGGGGTF
AHEAVITQEMARGICTSLGNNVHSGIVAHYLLNYGTQAQKEKWLPQMASGEMVAAIAMSEPGAGSDLKSVRTRAVREKTE
NGDCYRINGAKTFITNGYHADLVCLIAKTDPEAGTRGVSLIMVETRDLPGFRRGRILEKIGQKGQDTAELFFDDVLVPCE
NLLGEQEGQGFYQLMQQLPQERMIIALGAVASMQRAIELTTDYVRERKVFGQPLLDLQNTRFKLAECKTNATIAATFVND
CMVRLMEGKLDAATAAMAKWWCTQRNCEIIDECLQLHGGYGYMLEYPIARMYANARVGKIYGGSNEIMKELVARTL
>Mature_395_residues
GSPELNATAAASTEAPWMTEDLVLFRDTVRRFVERELAPNESRWAEQGYIDRDVWRRAGQIGLLCASIPEEYGGGGGTFA
HEAVITQEMARGICTSLGNNVHSGIVAHYLLNYGTQAQKEKWLPQMASGEMVAAIAMSEPGAGSDLKSVRTRAVREKTEN
GDCYRINGAKTFITNGYHADLVCLIAKTDPEAGTRGVSLIMVETRDLPGFRRGRILEKIGQKGQDTAELFFDDVLVPCEN
LLGEQEGQGFYQLMQQLPQERMIIALGAVASMQRAIELTTDYVRERKVFGQPLLDLQNTRFKLAECKTNATIAATFVNDC
MVRLMEGKLDAATAAMAKWWCTQRNCEIIDECLQLHGGYGYMLEYPIARMYANARVGKIYGGSNEIMKELVARTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=45.1871657754011, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=31.5926892950392, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI7656849, Length=381, Percent_Identity=33.5958005249344, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=32.5648414985591, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4501859, Length=395, Percent_Identity=30.379746835443, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=32.6315789473684, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=32.8083989501312, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=32.8083989501312, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=32.4742268041237, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI4557235, Length=388, Percent_Identity=32.4742268041237, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=30.6282722513089, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=28.0205655526992, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI7669494, Length=374, Percent_Identity=28.3422459893048, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI48976061, Length=397, Percent_Identity=26.448362720403, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI211971008, Length=397, Percent_Identity=26.448362720403, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI38505218, Length=296, Percent_Identity=26.3513513513513, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=28.0839895013123, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786223, Length=359, Percent_Identity=28.133704735376, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87082384, Length=279, Percent_Identity=30.1075268817204, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=31.331592689295, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17551932, Length=396, Percent_Identity=30.3030303030303, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=32.258064516129, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=31.151832460733, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=395, Percent_Identity=29.873417721519, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=370, Percent_Identity=31.0810810810811, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=399, Percent_Identity=30.5764411027569, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=29.1338582677165, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=367, Percent_Identity=28.6103542234332, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=361, Percent_Identity=31.3019390581717, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=31.1188811188811, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=312, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=385, Percent_Identity=26.4935064935065, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=31.7596566523605, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=28.0442804428044, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=337, Percent_Identity=27.893175074184, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=25.3164556962025, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=279, Percent_Identity=27.5985663082437, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=279, Percent_Identity=27.5985663082437, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355753, Length=385, Percent_Identity=33.5064935064935, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21356377, Length=393, Percent_Identity=32.3155216284987, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=32.4607329842932, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24660351, Length=382, Percent_Identity=30.1047120418848, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=28.8713910761155, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363737, Length=349, Percent_Identity=31.8051575931232, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=26.8929503916449, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43904; Mature: 43773

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSPELNATAAASTEAPWMTEDLVLFRDTVRRFVERELAPNESRWAEQGYIDRDVWRRAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCC
QIGLLCASIPEEYGGGGGTFAHEAVITQEMARGICTSLGNNVHSGIVAHYLLNYGTQAQK
CCEEEHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
EKWLPQMASGEMVAAIAMSEPGAGSDLKSVRTRAVREKTENGDCYRINGAKTFITNGYHA
HHCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCC
DLVCLIAKTDPEAGTRGVSLIMVETRDLPGFRRGRILEKIGQKGQDTAELFFDDVLVPCE
EEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NLLGEQEGQGFYQLMQQLPQERMIIALGAVASMQRAIELTTDYVRERKVFGQPLLDLQNT
HHCCCCCCCHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
RFKLAECKTNATIAATFVNDCMVRLMEGKLDAATAAMAKWWCTQRNCEIIDECLQLHGGY
CEEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
GYMLEYPIARMYANARVGKIYGGSNEIMKELVARTL
CHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
GSPELNATAAASTEAPWMTEDLVLFRDTVRRFVERELAPNESRWAEQGYIDRDVWRRAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCC
QIGLLCASIPEEYGGGGGTFAHEAVITQEMARGICTSLGNNVHSGIVAHYLLNYGTQAQK
CCEEEHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
EKWLPQMASGEMVAAIAMSEPGAGSDLKSVRTRAVREKTENGDCYRINGAKTFITNGYHA
HHCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCC
DLVCLIAKTDPEAGTRGVSLIMVETRDLPGFRRGRILEKIGQKGQDTAELFFDDVLVPCE
EEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NLLGEQEGQGFYQLMQQLPQERMIIALGAVASMQRAIELTTDYVRERKVFGQPLLDLQNT
HHCCCCCCCHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
RFKLAECKTNATIAATFVNDCMVRLMEGKLDAATAAMAKWWCTQRNCEIIDECLQLHGGY
CEEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
GYMLEYPIARMYANARVGKIYGGSNEIMKELVARTL
CHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]