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The map label for this gene is paaG [C]

Identifier: 73537386

GI number: 73537386

Start: 101731

End: 102510

Strand: Direct

Name: paaG [C]

Synonym: Reut_B3551

Alternate gene names: 73537386

Gene position: 101731-102510 (Clockwise)

Preceding gene: 73537385

Following gene: 73537387

Centisome position: 3.73

GC content: 64.74

Gene sequence:

>780_bases
ATGGAAACGATTCGCTATGCCGTGGAAGACGGCATTGCCACCCTTACGCTCGATTACCCGGCCCGCAAGAATGCGCTGAA
CGGCGTCATGCGCCGCGAAATCGGCGATGTGATGCACGAGCTGCGCCAGGACACCAGCGTGCGCGCGCTGATCCTGACTG
GTGCCGGCACCGATTTCTGCTCGGGCGGGGACATCAGCTCCATGCAGGGCGAGATCAGCGCAGCGCAGGGGCGCCAGCGG
CTGGGCAATATCCATCCGTGGCTCGAGACGCTGATCAATCTCGAGATTCCTGTCATTTCCGCGGTCGATGGCGCGGCTTT
TGGCGCGGGATTCAGCCTGGCGCTCACCGCTGACATCATCCTGGCCACCCCGCGTGCCCGGTTCGGGTTGCCGTTCCTGC
GTCTGGGTTTGATTCCGGATTGTGGCGTGTTTTACACATTGCCTCGCATGGTCGGCCTCCAGCGCGCCAAGGCGCTGATG
TTCTCGATGCGCGAGCTCAACGCCGAGGCGGCCCAGGAGCAGGGCATCGTCATGGAGATCGTGCCAGCAGACAGCCTGCA
GGAGCGCGCCCGTGCGATGGCCCGCGCCTTCACCGAGGCCTCCCCCGTTGCGCTGGCGCTAACCAAGAAGGCGCTCAATG
CGTCGCTGAACCAGGACCTGCACAGCATGCTGGCCATGGAGGCGGACGGCCAGGGCATCGCGTTCGCCACGGAATACCGC
CAGGAGGCCGCGAATCGCTTCCTGTCCAAGCAGCCGCCGCGTTATCGCTGGCCTGACTAA

Upstream 100 bases:

>100_bases
GGCGACATGCCCAAGTGGGCCAAGATCGTACGCGACGCGCATATCCAGCTGGACTGAGCGCCAGTCAGGCATCGAACCGC
AGCATTACATGGAGTCATCA

Downstream 100 bases:

>100_bases
GTCCTGCGAAGCAACAGGGTGCGTGCGGCATGCTGCGCTGCGGTATGGCGGACAGGCGCCCACCTCGCAAGGCTTCAACG
AAATACGCCTATCTATATAG

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
METIRYAVEDGIATLTLDYPARKNALNGVMRREIGDVMHELRQDTSVRALILTGAGTDFCSGGDISSMQGEISAAQGRQR
LGNIHPWLETLINLEIPVISAVDGAAFGAGFSLALTADIILATPRARFGLPFLRLGLIPDCGVFYTLPRMVGLQRAKALM
FSMRELNAEAAQEQGIVMEIVPADSLQERARAMARAFTEASPVALALTKKALNASLNQDLHSMLAMEADGQGIAFATEYR
QEAANRFLSKQPPRYRWPD

Sequences:

>Translated_259_residues
METIRYAVEDGIATLTLDYPARKNALNGVMRREIGDVMHELRQDTSVRALILTGAGTDFCSGGDISSMQGEISAAQGRQR
LGNIHPWLETLINLEIPVISAVDGAAFGAGFSLALTADIILATPRARFGLPFLRLGLIPDCGVFYTLPRMVGLQRAKALM
FSMRELNAEAAQEQGIVMEIVPADSLQERARAMARAFTEASPVALALTKKALNASLNQDLHSMLAMEADGQGIAFATEYR
QEAANRFLSKQPPRYRWPD
>Mature_259_residues
METIRYAVEDGIATLTLDYPARKNALNGVMRREIGDVMHELRQDTSVRALILTGAGTDFCSGGDISSMQGEISAAQGRQR
LGNIHPWLETLINLEIPVISAVDGAAFGAGFSLALTADIILATPRARFGLPFLRLGLIPDCGVFYTLPRMVGLQRAKALM
FSMRELNAEAAQEQGIVMEIVPADSLQERARAMARAFTEASPVALALTKKALNASLNQDLHSMLAMEADGQGIAFATEYR
QEAANRFLSKQPPRYRWPD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=29.7959183673469, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI45643119, Length=256, Percent_Identity=28.515625, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI260275230, Length=256, Percent_Identity=28.515625, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI260274832, Length=256, Percent_Identity=28.515625, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=30.7692307692308, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=26.3779527559055, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI70995211, Length=225, Percent_Identity=28.4444444444444, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=23.5059760956175, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=23.5059760956175, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI116235487, Length=189, Percent_Identity=26.984126984127, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4757966, Length=225, Percent_Identity=24, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI51538581, Length=225, Percent_Identity=24, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=23.1075697211155, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=23.1075697211155, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI221307494, Length=251, Percent_Identity=23.1075697211155, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI157694516, Length=239, Percent_Identity=25.9414225941423, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI68989263, Length=172, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI213417737, Length=232, Percent_Identity=25.8620689655172, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4757968, Length=252, Percent_Identity=22.6190476190476, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI49355787, Length=252, Percent_Identity=22.6190476190476, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=188, Percent_Identity=27.1276595744681, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI37594471, Length=243, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI37594469, Length=243, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=35.7692307692308, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=34.9794238683128, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI221142681, Length=214, Percent_Identity=34.5794392523364, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790281, Length=190, Percent_Identity=32.6315789473684, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=31.9796954314721, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082183, Length=255, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=31.4516129032258, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=220, Percent_Identity=32.7272727272727, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=31.3492063492063, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17535521, Length=250, Percent_Identity=25.2, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=29.296875, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=212, Percent_Identity=27.8301886792453, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=251, Percent_Identity=23.9043824701195, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=26.775956284153, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=189, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=166, Percent_Identity=24.0963855421687, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=32.1138211382114, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=32.1138211382114, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=29.4820717131474, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=32.093023255814, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654903, Length=184, Percent_Identity=27.7173913043478, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357171, Length=185, Percent_Identity=28.1081081081081, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=20.8661417322835, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28238; Mature: 28238

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIRYAVEDGIATLTLDYPARKNALNGVMRREIGDVMHELRQDTSVRALILTGAGTDFC
CCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SGGDISSMQGEISAAQGRQRLGNIHPWLETLINLEIPVISAVDGAAFGAGFSLALTADII
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCHHCCCCHHHEEHHHE
LATPRARFGLPFLRLGLIPDCGVFYTLPRMVGLQRAKALMFSMRELNAEAAQEQGIVMEI
EECCCHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VPADSLQERARAMARAFTEASPVALALTKKALNASLNQDLHSMLAMEADGQGIAFATEYR
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
QEAANRFLSKQPPRYRWPD
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
METIRYAVEDGIATLTLDYPARKNALNGVMRREIGDVMHELRQDTSVRALILTGAGTDFC
CCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SGGDISSMQGEISAAQGRQRLGNIHPWLETLINLEIPVISAVDGAAFGAGFSLALTADII
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCHHCCCCHHHEEHHHE
LATPRARFGLPFLRLGLIPDCGVFYTLPRMVGLQRAKALMFSMRELNAEAAQEQGIVMEI
EECCCHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VPADSLQERARAMARAFTEASPVALALTKKALNASLNQDLHSMLAMEADGQGIAFATEYR
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
QEAANRFLSKQPPRYRWPD
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA