Click here to switch to the map view.

The map label for this gene is hdfR [H]

Identifier: 73537333

GI number: 73537333

Start: 35323

End: 36189

Strand: Direct

Name: hdfR [H]

Synonym: Reut_B3498

Alternate gene names: 73537333

Gene position: 35323-36189 (Clockwise)

Preceding gene: 73537332

Following gene: 73537335

Centisome position: 1.3

GC content: 63.32

Gene sequence:

>867_bases
ATGGATATCGAACTTGCCCGCACCTTTCTGCAAGTGGTACGGACCGGCAGCCTTCTCGCGGCGGCCGACAAGCTGCATGT
GACGCAGACCGCCGTCACGGCGCGCATCAAGAGCCTGGAATCGCAACTCAACTGCCGGCTGTTCGACCGCAACAAGGCAG
GCGCCAGGCTGACGGCCGATGGTCAGCGCTTTCTCGGGTATGCCAGCCAGCTCGTGCAGACTTGGGAAGCGGCATGCCGA
GACCTGCCGCTGCCCGCTGGACTCGGCAGCATGCTGACGTTCGGCGCGGAGATCAGCCTGGGTAACCCCCTTGTGCTGTT
GTGGGCTACGCGCCTGCGCCAGCAGATGCCGGATCACGCAGTGCGCGCCGAAGTCGGCGATGGCGCGGAATTACAACGCA
AGCTGCAGTCGGGCACGCTGGACGCCGCGCTGGTCTACCAGCCGGAATACGCGGCTGGCCTGCACGTCGAGCATCTCATG
GAAGAGAAGCTGATCCAGATCCGCTCCACGCAGCGCGCTGGATCTTATGTCTATGTCGACTGGGGGCCAGAATTCCGCCG
GCAGCATGACAGCGCGTTGCCGGGGTACGCCAGGTCATCGCTGTACTTCAATCTCGGGCCGCTGGCGCTGCAGTACATCC
TGCAATATGGCGGCAGCGGCTATTTCCGCACGCGGGTTGTGCAGAGCTATCTGGACAGCGGCGTGCTGGAACGCGTCGAG
GACGCATCGGAATTCTCGTATCCGGTATTCCTCGTCCATGCCGGTTCGCCGGGGAGACAAGCCCTGGACGACGCGGTCCG
GATTCTCCACGACATCGTGCGTGAAGAATCGGACTGGTCGCAGCGCTGGGATTTTCCGCTGTCTTGA

Upstream 100 bases:

>100_bases
CAAGGTGAGTGGCGCGCCCTCCGCCCGGGCATGGTAAGGTTGGCAGCCACGCCGCCGTGCGGCGCATGGCACTCCACCTG
TCCAGCCCGCTTCGCTTTGC

Downstream 100 bases:

>100_bases
AGGGGGCCGAGGCGCTCAGGCGCGCACCGGCACCAAGCGCGGGACGGGATGCGCGGCCGGCAAGATGCGCAAGCGCCGGA
TACGCTTGCCGCCGCCACGG

Product: regulatory protein LysR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDIELARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFDRNKAGARLTADGQRFLGYASQLVQTWEAACR
DLPLPAGLGSMLTFGAEISLGNPLVLLWATRLRQQMPDHAVRAEVGDGAELQRKLQSGTLDAALVYQPEYAAGLHVEHLM
EEKLIQIRSTQRAGSYVYVDWGPEFRRQHDSALPGYARSSLYFNLGPLALQYILQYGGSGYFRTRVVQSYLDSGVLERVE
DASEFSYPVFLVHAGSPGRQALDDAVRILHDIVREESDWSQRWDFPLS

Sequences:

>Translated_288_residues
MDIELARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFDRNKAGARLTADGQRFLGYASQLVQTWEAACR
DLPLPAGLGSMLTFGAEISLGNPLVLLWATRLRQQMPDHAVRAEVGDGAELQRKLQSGTLDAALVYQPEYAAGLHVEHLM
EEKLIQIRSTQRAGSYVYVDWGPEFRRQHDSALPGYARSSLYFNLGPLALQYILQYGGSGYFRTRVVQSYLDSGVLERVE
DASEFSYPVFLVHAGSPGRQALDDAVRILHDIVREESDWSQRWDFPLS
>Mature_288_residues
MDIELARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFDRNKAGARLTADGQRFLGYASQLVQTWEAACR
DLPLPAGLGSMLTFGAEISLGNPLVLLWATRLRQQMPDHAVRAEVGDGAELQRKLQSGTLDAALVYQPEYAAGLHVEHLM
EEKLIQIRSTQRAGSYVYVDWGPEFRRQHDSALPGYARSSLYFNLGPLALQYILQYGGSGYFRTRVVQSYLDSGVLERVE
DASEFSYPVFLVHAGSPGRQALDDAVRILHDIVREESDWSQRWDFPLS

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=270, Percent_Identity=28.8888888888889, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787601, Length=167, Percent_Identity=29.940119760479, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788297, Length=186, Percent_Identity=26.8817204301075, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32172; Mature: 32172

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIELARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFDRNKAGARLTAD
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEECC
GQRFLGYASQLVQTWEAACRDLPLPAGLGSMLTFGAEISLGNPLVLLWATRLRQQMPDHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEECCCCCCHHHHHHHHHHHCCCHH
VRAEVGDGAELQRKLQSGTLDAALVYQPEYAAGLHVEHLMEEKLIQIRSTQRAGSYVYVD
HHCCCCCCHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
WGPEFRRQHDSALPGYARSSLYFNLGPLALQYILQYGGSGYFRTRVVQSYLDSGVLERVE
CCHHHHHHCCCCCCCCHHCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DASEFSYPVFLVHAGSPGRQALDDAVRILHDIVREESDWSQRWDFPLS
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MDIELARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFDRNKAGARLTAD
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEECC
GQRFLGYASQLVQTWEAACRDLPLPAGLGSMLTFGAEISLGNPLVLLWATRLRQQMPDHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEECCCCCCHHHHHHHHHHHCCCHH
VRAEVGDGAELQRKLQSGTLDAALVYQPEYAAGLHVEHLMEEKLIQIRSTQRAGSYVYVD
HHCCCCCCHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
WGPEFRRQHDSALPGYARSSLYFNLGPLALQYILQYGGSGYFRTRVVQSYLDSGVLERVE
CCHHHHHHCCCCCCCCHHCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DASEFSYPVFLVHAGSPGRQALDDAVRILHDIVREESDWSQRWDFPLS
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA