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The map label for this gene is mmgC [H]

Identifier: 73537335

GI number: 73537335

Start: 36808

End: 37965

Strand: Direct

Name: mmgC [H]

Synonym: Reut_B3500

Alternate gene names: 73537335

Gene position: 36808-37965 (Clockwise)

Preceding gene: 73537333

Following gene: 73537336

Centisome position: 1.35

GC content: 63.9

Gene sequence:

>1158_bases
ATGCAACGCCTAATCTTCGACGCCGAACACGAGAGCTTTCGCGAGTCCGCGCGCCGTTTCTACCAGCGCGAGGTTGGTCC
GCACGGCGAGCGATGGCGCGAGCAGGGTTGCGTGGACCGGGACGTGTTTCGCAAGGCTGGGGAGCAGGGCTATCTGCTGA
TGTGGGCGGACGAGAAGTACGGCGGCGCGGGCGTGGATGACTTCCGCTACGAACAGATCCTGATCGAGGAAAATGCGCGC
CATGGCGATACGGGTTTCTTCGGCACGCTGCATTCGCGGCTTGTGGCGCCCTATGTCGGCCGCATCGGCAACGAGGAGCA
GCGCCAGCGTTTGCTGCCGGCCGCGGCGCGCGGCGAGAAGATCTTCGCCATTGCGATGACCGAGCCGCAGACCGGCTCGG
ATCTGGCCGGCATACGCACCCGCGCGGAGGATAAGGGCGACCACTGGCTGCTCAATGGCGCCAAGACCTATATCTCGAAC
GGGCAACTCGCCGACTACGTGGTCGTGGTGGCGCGCACCGATCCGGAACGCAGCCATGGGCTCGGCCTGTTCATCGTCGA
GCGCGACATGCCCGGGTTCCAGCGCGGACGCAAGCTGCGCAAAATGGGCCTGCACTCGCAAGATACTTCCGAACTCTTCT
TCGATAACGTCAGGGTGCCGAAGTCCAATGTGCTCGGCGAACCGGGACAGGGCTTCCGCTATCTGACGCGCCACCTGGCC
GAGGAGCGCCTGATCGGCGCCTGCGGCTACATGGCGTCGGCCCAGGTGGCGTTCGATATCACGCTGGATTACGTCAAGGA
GCGCAAGGCGTTCGGCCGGGCGATCGGCACGTTCCAGGATTCCCGCTTCAGGCTGGCGGAGTTGCGTGCGCAGCTCGACG
CACTGCAGACCTTCGTCGACCAGTGCGTGCTGCAGCACAACGCCGGCACGCTGACAGTCGAAACCGCGGCTTCGGCCAAA
CTACTGACTTCGGAACTGCAGGGGCGGGTGGTCGACGAAGGCGTTCAGTTTCACGGCGGCGCGGGTTATATGGAGGAGTA
CCGCATCTGCCGCATGTACACCGATGCGCGAATCTCTCGAATCTATGCGGGCAGCAGCGAGATCATGAAAGAGATCATCG
GCCGTAGCCTTGGACTCGATGACCGGGCGAGGGCATAG

Upstream 100 bases:

>100_bases
ACGGCGCACCCAAAATCATCCTTTCCGACGAACCTGACAACGGCCGCAAGGCCGACACTGGTCCGATTCCGTCAGCCAAA
AACGAGAAAGGAGACAACCC

Downstream 100 bases:

>100_bases
CGACCTCGCTGTCATGAATGCACCTATATGGTGCATCCTGTGGGCCGAGCTACTGGGATTTTCCCTTGATTTTGCGTTTT
CGCAGCAATTAACGTAGTTT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQRLIFDAEHESFRESARRFYQREVGPHGERWREQGCVDRDVFRKAGEQGYLLMWADEKYGGAGVDDFRYEQILIEENAR
HGDTGFFGTLHSRLVAPYVGRIGNEEQRQRLLPAAARGEKIFAIAMTEPQTGSDLAGIRTRAEDKGDHWLLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERDMPGFQRGRKLRKMGLHSQDTSELFFDNVRVPKSNVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDITLDYVKERKAFGRAIGTFQDSRFRLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRVVDEGVQFHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRARA

Sequences:

>Translated_385_residues
MQRLIFDAEHESFRESARRFYQREVGPHGERWREQGCVDRDVFRKAGEQGYLLMWADEKYGGAGVDDFRYEQILIEENAR
HGDTGFFGTLHSRLVAPYVGRIGNEEQRQRLLPAAARGEKIFAIAMTEPQTGSDLAGIRTRAEDKGDHWLLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERDMPGFQRGRKLRKMGLHSQDTSELFFDNVRVPKSNVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDITLDYVKERKAFGRAIGTFQDSRFRLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRVVDEGVQFHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRARA
>Mature_385_residues
MQRLIFDAEHESFRESARRFYQREVGPHGERWREQGCVDRDVFRKAGEQGYLLMWADEKYGGAGVDDFRYEQILIEENAR
HGDTGFFGTLHSRLVAPYVGRIGNEEQRQRLLPAAARGEKIFAIAMTEPQTGSDLAGIRTRAEDKGDHWLLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERDMPGFQRGRKLRKMGLHSQDTSELFFDNVRVPKSNVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDITLDYVKERKAFGRAIGTFQDSRFRLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRVVDEGVQFHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRARA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=45.9317585301837, Blast_Score=339, Evalue=2e-93,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=33.42175066313, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=34.8837209302326, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=31.283422459893, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=32.4324324324324, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=31.4666666666667, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=32, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=32, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=31.151832460733, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4557235, Length=372, Percent_Identity=31.989247311828, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI76496475, Length=372, Percent_Identity=31.989247311828, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=28.1914893617021, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI7669494, Length=350, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI48976061, Length=366, Percent_Identity=26.5027322404372, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=366, Percent_Identity=26.5027322404372, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38505218, Length=320, Percent_Identity=24.6875, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=30.3370786516854, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1786223, Length=279, Percent_Identity=29.3906810035842, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082384, Length=271, Percent_Identity=27.3062730627306, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=36.436170212766, Blast_Score=244, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=33.5106382978723, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=32.4396782841823, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=30.5630026809651, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=31.6216216216216, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=30.0791556728232, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=382, Percent_Identity=32.1989528795811, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=30.3430079155673, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=30.6233062330623, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=31.4285714285714, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=32.7338129496403, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=285, Percent_Identity=31.5789473684211, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=275, Percent_Identity=31.2727272727273, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=34.2105263157895, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=28, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=26.5560165975104, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=26.9896193771626, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=33.7696335078534, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=34.0540540540541, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=30.8108108108108, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=29.9465240641711, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=30.2702702702703, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281363737, Length=335, Percent_Identity=29.2537313432836, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=27.5132275132275, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43460; Mature: 43460

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLIFDAEHESFRESARRFYQREVGPHGERWREQGCVDRDVFRKAGEQGYLLMWADEKY
CCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GGAGVDDFRYEQILIEENARHGDTGFFGTLHSRLVAPYVGRIGNEEQRQRLLPAAARGEK
CCCCCCCHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHCCCCE
IFAIAMTEPQTGSDLAGIRTRAEDKGDHWLLNGAKTYISNGQLADYVVVVARTDPERSHG
EEEEEECCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEEEEECCCCCCCC
LGLFIVERDMPGFQRGRKLRKMGLHSQDTSELFFDNVRVPKSNVLGEPGQGFRYLTRHLA
CEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHH
EERLIGACGYMASAQVAFDITLDYVKERKAFGRAIGTFQDSRFRLAELRAQLDALQTFVD
HHHHHHHHCCHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QCVLQHNAGTLTVETAASAKLLTSELQGRVVDEGVQFHGGAGYMEEYRICRMYTDARISR
HHHHHCCCCEEEEECCHHHHHHHHHHCCCCHHCCCEECCCCCHHHHHHHHHHHHHHHHHH
IYAGSSEIMKEIIGRSLGLDDRARA
HCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQRLIFDAEHESFRESARRFYQREVGPHGERWREQGCVDRDVFRKAGEQGYLLMWADEKY
CCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GGAGVDDFRYEQILIEENARHGDTGFFGTLHSRLVAPYVGRIGNEEQRQRLLPAAARGEK
CCCCCCCHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHCCCCE
IFAIAMTEPQTGSDLAGIRTRAEDKGDHWLLNGAKTYISNGQLADYVVVVARTDPERSHG
EEEEEECCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEEEEECCCCCCCC
LGLFIVERDMPGFQRGRKLRKMGLHSQDTSELFFDNVRVPKSNVLGEPGQGFRYLTRHLA
CEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHH
EERLIGACGYMASAQVAFDITLDYVKERKAFGRAIGTFQDSRFRLAELRAQLDALQTFVD
HHHHHHHHCCHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QCVLQHNAGTLTVETAASAKLLTSELQGRVVDEGVQFHGGAGYMEEYRICRMYTDARISR
HHHHHCCCCEEEEECCHHHHHHHHHHCCCCHHCCCEECCCCCHHHHHHHHHHHHHHHHHH
IYAGSSEIMKEIIGRSLGLDDRARA
HCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]