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The map label for this gene is aroB [H]

Identifier: 73542813

GI number: 73542813

Start: 3439111

End: 3440217

Strand: Reverse

Name: aroB [H]

Synonym: Reut_A3129

Alternate gene names: 73542813

Gene position: 3440217-3439111 (Counterclockwise)

Preceding gene: 73542814

Following gene: 73542812

Centisome position: 90.38

GC content: 64.59

Gene sequence:

>1107_bases
ATGATCACGCTACAAGTCGACCTGGGAGAGCGCAGCTATCCCATCCATATCGGTACCGGCCTGCTCGGCAACGCCGAGCT
GCTGCGCCCGCATGTGCGCGGCCAGCACGCCGTTATCGTCACCAATGAAACCGTCGGCCCGCTCTACGCGGCCCGCGTCG
AAGCGAGCCTGAAGGAACTGGGCAAGACCGTGCGCGTGGTCACGCTGCCCGACGGCGAAGCCTTCAAGCAGTGGGAAACG
CTGAACCTGATCTTCGATGCGCTGCTTTCCGCTGGCGCTGATCGCAAGACCACGCTGGTCGCGCTGGGCGGCGGCGTGGT
GGGCGACATGACCGGGTTTGCGGCGGCGTGCTACATGCGCGGCGTGCCGTTCGTGCAGGTGCCGACCACGCTGCTGTCGC
AGGTGGATTCGTCGGTTGGCGGCAAGACCGGCATCAATCACCCGCTCGGCAAGAACATGATTGGCGCGTTCCACCAGCCC
AACGCGGTGATTGCCGACATCGACACGCTGCGTACGCTGCCTGCACGCGAGCTGGCAGCCGGCATGGCCGAAGTCATCAA
GCACGGCGCGATCGCCGACGCCGATTACTTCGCCTGGATCGAGCGCAATATCGCCGCGCTGAACAGTTGCGACCCGGACC
TGATGGCGCTGGCCGTACAGCGCTCGTGCGAGATCAAGGCTGGTGTCGTGGCCCAGGACGAGCGCGAAGGCGGATTGCGT
GCAATCCTGAACTTCGGCCATACCTTCGGCCATGCCATCGAAGCCGGCATGGGCTACGGCGAATGGCTGCATGGCGAAGC
AGTGGGCTGCGGCATGGTGATGGCGGCGGACCTGTCGCACCGGCTCGGCTTTATCGACACGGAGACGCGTGCGCGCATCC
GGCAACTGACGCAGGCGGCCATGCTACCCATCGTCGCGCCGGAACTGGGCACCGACCGCTATATCGAACTGATGAAGGTG
GACAAGAAGGCCGAAGCCGGCAGCATCAAGTTCATCCTGCTGAAGAAGCTTGGCGAAGCGTTCATCACCACGGTTCCCGA
TACCGATCTGCGCGCGACACTGGCGCAGGCAGTCCTTAAACCCCCCACCGAGGCCACGGTCGCGTAA

Upstream 100 bases:

>100_bases
TGGCACAGCTTGCTAATATGGTGCTGATGCAGCTGGAAATGGCCGGTTTCCGCATCGACACCGCCGCCGCGTCGGACCAG
CCGGCCAACGATACGCATTC

Downstream 100 bases:

>100_bases
ACGATCGGTTATGCCTCGCAACCCTGACCCAGCCCACGGATTGCCGCATGACCGACCTTGAAAGCCACCTCGCTCCCTAC
GCCGCCCGCTCCGCGCAGAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MITLQVDLGERSYPIHIGTGLLGNAELLRPHVRGQHAVIVTNETVGPLYAARVEASLKELGKTVRVVTLPDGEAFKQWET
LNLIFDALLSAGADRKTTLVALGGGVVGDMTGFAAACYMRGVPFVQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIERNIAALNSCDPDLMALAVQRSCEIKAGVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDTETRARIRQLTQAAMLPIVAPELGTDRYIELMKV
DKKAEAGSIKFILLKKLGEAFITTVPDTDLRATLAQAVLKPPTEATVA

Sequences:

>Translated_368_residues
MITLQVDLGERSYPIHIGTGLLGNAELLRPHVRGQHAVIVTNETVGPLYAARVEASLKELGKTVRVVTLPDGEAFKQWET
LNLIFDALLSAGADRKTTLVALGGGVVGDMTGFAAACYMRGVPFVQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIERNIAALNSCDPDLMALAVQRSCEIKAGVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDTETRARIRQLTQAAMLPIVAPELGTDRYIELMKV
DKKAEAGSIKFILLKKLGEAFITTVPDTDLRATLAQAVLKPPTEATVA
>Mature_368_residues
MITLQVDLGERSYPIHIGTGLLGNAELLRPHVRGQHAVIVTNETVGPLYAARVEASLKELGKTVRVVTLPDGEAFKQWET
LNLIFDALLSAGADRKTTLVALGGGVVGDMTGFAAACYMRGVPFVQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIERNIAALNSCDPDLMALAVQRSCEIKAGVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDTETRARIRQLTQAAMLPIVAPELGTDRYIELMKV
DKKAEAGSIKFILLKKLGEAFITTVPDTDLRATLAQAVLKPPTEATVA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=345, Percent_Identity=55.6521739130435, Blast_Score=355, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6320332, Length=395, Percent_Identity=38.7341772151899, Blast_Score=220, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39239; Mature: 39239

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLQVDLGERSYPIHIGTGLLGNAELLRPHVRGQHAVIVTNETVGPLYAARVEASLKEL
CEEEEEECCCCCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
GKTVRVVTLPDGEAFKQWETLNLIFDALLSAGADRKTTLVALGGGVVGDMTGFAAACYMR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFVQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPNAVIADIDTLRTLPARELAA
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIERNIAALNSCDPDLMALAVQRSCEIKAGVVAQDEREGGLR
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCEECCCCCCCHH
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDTETRARIRQLTQAA
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MLPIVAPELGTDRYIELMKVDKKAEAGSIKFILLKKLGEAFITTVPDTDLRATLAQAVLK
HCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHEECCCCCHHHHHHHHHHHC
PPTEATVA
CCCCCCCC
>Mature Secondary Structure
MITLQVDLGERSYPIHIGTGLLGNAELLRPHVRGQHAVIVTNETVGPLYAARVEASLKEL
CEEEEEECCCCCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
GKTVRVVTLPDGEAFKQWETLNLIFDALLSAGADRKTTLVALGGGVVGDMTGFAAACYMR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFVQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPNAVIADIDTLRTLPARELAA
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIERNIAALNSCDPDLMALAVQRSCEIKAGVVAQDEREGGLR
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCEECCCCCCCHH
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDTETRARIRQLTQAA
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MLPIVAPELGTDRYIELMKVDKKAEAGSIKFILLKKLGEAFITTVPDTDLRATLAQAVLK
HCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHEECCCCCHHHHHHHHHHHC
PPTEATVA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA