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The map label for this gene is murA

Identifier: 73542797

GI number: 73542797

Start: 3420341

End: 3421591

Strand: Reverse

Name: murA

Synonym: Reut_A3113

Alternate gene names: 73542797

Gene position: 3421591-3420341 (Counterclockwise)

Preceding gene: 73542798

Following gene: 73542796

Centisome position: 89.89

GC content: 65.63

Gene sequence:

>1251_bases
ATGGACAAATTCCAGATCCAGGGCAATGGCCCGCTCAAAGGCGAGATCCGTGTTTCCGGCGCCAAAAACGCCGCGCTGCC
GATCCTGTGCGCCGGCCTGCTGACGGCCGATACCGTCACCATCGACAACGTGCCCAACCTGCAGGACACGCGCACCATGC
TCAAGCTGCTGCGGCAGATGGGCATGCACGCCGAGATGACCGGCAGCACCGCCACGCTCAAGGGCACCGATATCAATTCG
CCCGAGGCGCCGTACGAGCTGGTGAAGACCATGCGCGCGTCGATCCTGGTGCTCGGCCCGCTGGTCGCGCGCTTTGGCGA
GGCGCGTGTGTCGTTGCCGGGCGGCTGCGGCATTGGCGCGCGCCCGGTGGACCAGCACATCAAGGGCCTGCAGGCCATGG
GTGCCGAAATCAGTATCGAACACGGCTTCATCCACGCCCGTGCGTCGCGCCTGAAGGGCGCGCGCGTGGTGACGGACATG
ATTACCGTGACCGGCACCGAAAACCTGCTGATGGCCGCGACGCTTGCCGATGGCGAGACAGTGCTCGAAAACGCCGCGCG
CGAACCCGAAGTGACCGACCTTGCGAACCTGCTCGTCAAGATGGGCGCGAAGATCGACGGCATCGGTACTGACCGCCTGA
TCGTGCAGGGCGTCGACAAGCTGCATGGCGCGACGCATTCGGTCGTCGCTGACCGCATCGAGGCCGGCACTTTCCTGTGC
GCGGCCGCTGCCTCGCTGGGCGACCTGGTCCTGCGCGATATTCCGCCGCTGATCCTCGACGCGGTGCTGATCAAGCTGCG
CGAGGCCGGTGCCAATATCGAAACCGGTGATGACTGGATCCGCCTGTCCATGTCGCAACGCGCGCAGGCCGTGAGCTTCC
GCACCTCGGAATACCCGGCGTTCCCGACCGACATGCAGGCCCAGTTCATGGCGCTCAATGCCGTGGCCGAAGGCACCGCC
CGCATTACCGAGACGATCTTCGAAAACCGCTTCATGCACGTGCAGGAACTGAACCGCCTGGGCGCCAACATCACCGCCGA
AGGCAACACGGCCGTGGTGACCGGCGTGCCGCGCCTGTCCGGCGCCAGCGTGATGGCGACCGACCTGCGCGCATCGGCGA
GCCTGGTCATCGCTGGCCTGGTCGCAGATGGCGATACCGTGATCGATCGCATCTACCATCTGGACCGCGGTTACGACCGC
ATGGAAGACAAGTTGTCGGCAGTCGGCGCCAAGATCCGCCGCATCGCCTGA

Upstream 100 bases:

>100_bases
GACGGCAGCTTCACCGAATCGAGCCGCGCGCCTGGCGCGCGTGGTTCCCGCGAAATCGATGCCGGACGTGATGACCCCGT
CCGGCCGCAACTGACAGAAC

Downstream 100 bases:

>100_bases
GGAACCCGATGAGCCCCGCATTCAACGCTTCGCCCAACCAGCTCACGCTGGCGCTTTCCAAGGGCCGCATCTTCAAGGAA
ACGCTGCCGCTGCTCGAAGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQMGMHAEMTGSTATLKGTDINS
PEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDM
ITVTGTENLLMAATLADGETVLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLC
AAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDR
MEDKLSAVGAKIRRIA

Sequences:

>Translated_416_residues
MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQMGMHAEMTGSTATLKGTDINS
PEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDM
ITVTGTENLLMAATLADGETVLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLC
AAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDR
MEDKLSAVGAKIRRIA
>Mature_416_residues
MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQMGMHAEMTGSTATLKGTDINS
PEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDM
ITVTGTENLLMAATLADGETVLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLC
AAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDR
MEDKLSAVGAKIRRIA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=59.7122302158273, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_CUPPJ (Q46WL0)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_297317.1
- ProteinModelPortal:   Q46WL0
- SMR:   Q46WL0
- GeneID:   3611939
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A3113
- NMPDR:   fig|264198.3.peg.2288
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   REUT264198:REUT_A3113-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44225; Mature: 44225

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQM
CCCEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
GMHAEMTGSTATLKGTDINSPEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGA
CCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDMITVTGTENLLMAATLADGET
CCHHHHHHHHHHCCCEEEEECCEEHHHHHHCCCCCEEEHHEEECCCCCEEEEEEECCCHH
VLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
AAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHEEEEHHHHHHHHHEECCCCCC
FPTDMQAQFMALNAVAEGTARITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEEECCCCCC
GASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDRMEDKLSAVGAKIRRIA
CCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQM
CCCEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
GMHAEMTGSTATLKGTDINSPEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGA
CCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDMITVTGTENLLMAATLADGET
CCHHHHHHHHHHCCCEEEEECCEEHHHHHHCCCCCEEEHHEEECCCCCEEEEEEECCCHH
VLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
AAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHEEEEHHHHHHHHHEECCCCCC
FPTDMQAQFMALNAVAEGTARITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEEECCCCCC
GASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDRMEDKLSAVGAKIRRIA
CCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA