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The map label for this gene is yfeR [H]

Identifier: 73542757

GI number: 73542757

Start: 3383231

End: 3384145

Strand: Reverse

Name: yfeR [H]

Synonym: Reut_A3073

Alternate gene names: 73542757

Gene position: 3384145-3383231 (Counterclockwise)

Preceding gene: 73542763

Following gene: 73542750

Centisome position: 88.9

GC content: 65.9

Gene sequence:

>915_bases
GTGGCCAACATCGGCAACATGAACGTGTCGCTGCGGCAACTGCGCGCCTTTATCGCGGTGGCGCAGGAGCGGCATTTCAC
GCGCGCGGCGGAGAAGCTGGACCTGTCGCAGTCCTCTGTCAGCGCGCTGATCCACGAGCTCGAAGACAACCTCGGCCTGA
AGCTGTTCGACCGGCATACGCGCCAGCTCCACATCACGCAGGCTGGCGAGGAACTGCTGCCGCTCGTGAAGAAGGCGGTG
GCCGATATCGACAGCGCGATCGAGACGTCGAGCGAGTTGCGCACGCTGGGCCGCGGGCGCGTATCGATTGCGGCATCGTC
GATCCAGGCGGCACTGATGCTGCCGCGCTTCATTCGCGAGTTCAGCCTTGGACATCCGGGCGTGAAGGTCGACATCCACG
ATGTGTCAGAGCATGAGGTGCCGAAGATGGTCAGCTCGGGCGAGGTCGACTTCGGCATCGGCACGATTCCGGAAGGGCAG
CCCGACCTGACCGCGCACCGGCTATCGACGGATCCGTTTGTGATCGTGATGCCGCCCGACCATCCGCTGCTGCGGCGCAA
GACTCTGCGCTGGGAAGATGTGGCGCCCATTCCGTTGATCGGTCCGCACAAGGGCAATCCGATCCGCGACTGCCTCGATA
CCGCACTGGCCGCGCGCGGCATCACGCTGTCGCGGCTGCATGAGGTGCTGCTGCCGCTGACGATGGTCGGCATGGTCGAG
GCCGGCCTCGGTATCGCCGTGATGAGCGCCGCAGTGACGCGGCTGACCGAGGCGCTGGGACTGGCCACGGTCATGCCGAC
CGATCCGGTGATCCATCGCGAGATCTCGCTGCTGGTGCACGCGGACCGGTCGCTGTCGCCGCCGGCCCAGCGCTTCCGCG
ACCTGTTGATGCGCAATCGCGGCAATCTCGGTTAG

Upstream 100 bases:

>100_bases
AAGACCTCGAAACCTATTAATTGATCGTGTTACCCTCTGAATCAGATGCGCCGCGCGGATCTCCGCAGCAGGCGCGCACC
TGACCACAGGAGGAAGACAA

Downstream 100 bases:

>100_bases
TCGTCAGGCGGGCTCTTTCGCAAGGCCGTGCGCTTGCGGCTGCGGCGAGCGCGCATTGAACAGCACGTTCAGCAGCACCG
CGGACAGCGTGCCGAGCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MANIGNMNVSLRQLRAFIAVAQERHFTRAAEKLDLSQSSVSALIHELEDNLGLKLFDRHTRQLHITQAGEELLPLVKKAV
ADIDSAIETSSELRTLGRGRVSIAASSIQAALMLPRFIREFSLGHPGVKVDIHDVSEHEVPKMVSSGEVDFGIGTIPEGQ
PDLTAHRLSTDPFVIVMPPDHPLLRRKTLRWEDVAPIPLIGPHKGNPIRDCLDTALAARGITLSRLHEVLLPLTMVGMVE
AGLGIAVMSAAVTRLTEALGLATVMPTDPVIHREISLLVHADRSLSPPAQRFRDLLMRNRGNLG

Sequences:

>Translated_304_residues
MANIGNMNVSLRQLRAFIAVAQERHFTRAAEKLDLSQSSVSALIHELEDNLGLKLFDRHTRQLHITQAGEELLPLVKKAV
ADIDSAIETSSELRTLGRGRVSIAASSIQAALMLPRFIREFSLGHPGVKVDIHDVSEHEVPKMVSSGEVDFGIGTIPEGQ
PDLTAHRLSTDPFVIVMPPDHPLLRRKTLRWEDVAPIPLIGPHKGNPIRDCLDTALAARGITLSRLHEVLLPLTMVGMVE
AGLGIAVMSAAVTRLTEALGLATVMPTDPVIHREISLLVHADRSLSPPAQRFRDLLMRNRGNLG
>Mature_303_residues
ANIGNMNVSLRQLRAFIAVAQERHFTRAAEKLDLSQSSVSALIHELEDNLGLKLFDRHTRQLHITQAGEELLPLVKKAVA
DIDSAIETSSELRTLGRGRVSIAASSIQAALMLPRFIREFSLGHPGVKVDIHDVSEHEVPKMVSSGEVDFGIGTIPEGQP
DLTAHRLSTDPFVIVMPPDHPLLRRKTLRWEDVAPIPLIGPHKGNPIRDCLDTALAARGITLSRLHEVLLPLTMVGMVEA
GLGIAVMSAAVTRLTEALGLATVMPTDPVIHREISLLVHADRSLSPPAQRFRDLLMRNRGNLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=32.7702702702703, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=28.6689419795222, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=30.2325581395349, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787589, Length=169, Percent_Identity=36.094674556213, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788887, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=28.3737024221453, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367136, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788296, Length=215, Percent_Identity=29.7674418604651, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=27.5303643724696, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=25.8964143426295, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=28.6885245901639, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081904, Length=222, Percent_Identity=27.9279279279279, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787601, Length=187, Percent_Identity=29.9465240641711, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994962, Length=145, Percent_Identity=31.7241379310345, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789173, Length=169, Percent_Identity=32.5443786982249, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788626, Length=246, Percent_Identity=30.4878048780488, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=27.5747508305648, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787128, Length=126, Percent_Identity=29.3650793650794, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33220; Mature: 33089

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIGNMNVSLRQLRAFIAVAQERHFTRAAEKLDLSQSSVSALIHELEDNLGLKLFDRHT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCC
RQLHITQAGEELLPLVKKAVADIDSAIETSSELRTLGRGRVSIAASSIQAALMLPRFIRE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
FSLGHPGVKVDIHDVSEHEVPKMVSSGEVDFGIGTIPEGQPDLTAHRLSTDPFVIVMPPD
HCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCC
HPLLRRKTLRWEDVAPIPLIGPHKGNPIRDCLDTALAARGITLSRLHEVLLPLTMVGMVE
CHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AGLGIAVMSAAVTRLTEALGLATVMPTDPVIHREISLLVHADRSLSPPAQRFRDLLMRNR
HCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHCC
GNLG
CCCC
>Mature Secondary Structure 
ANIGNMNVSLRQLRAFIAVAQERHFTRAAEKLDLSQSSVSALIHELEDNLGLKLFDRHT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCC
RQLHITQAGEELLPLVKKAVADIDSAIETSSELRTLGRGRVSIAASSIQAALMLPRFIRE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
FSLGHPGVKVDIHDVSEHEVPKMVSSGEVDFGIGTIPEGQPDLTAHRLSTDPFVIVMPPD
HCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCC
HPLLRRKTLRWEDVAPIPLIGPHKGNPIRDCLDTALAARGITLSRLHEVLLPLTMVGMVE
CHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AGLGIAVMSAAVTRLTEALGLATVMPTDPVIHREISLLVHADRSLSPPAQRFRDLLMRNR
HCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHCC
GNLG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]