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The map label for this gene is ftsW [H]

Identifier: 73542664

GI number: 73542664

Start: 3268804

End: 3270045

Strand: Reverse

Name: ftsW [H]

Synonym: Reut_A2980

Alternate gene names: 73542664

Gene position: 3270045-3268804 (Counterclockwise)

Preceding gene: 73542665

Following gene: 73542663

Centisome position: 85.91

GC content: 62.88

Gene sequence:

>1242_bases
ATGAGTGAATCGCAGGTCAAGCGCAGCGGTTTCATCGGCGCCACCATCGGCAATGCCTGGGGTGGCCTGCGCGATGCGGT
GTCCGGCGTCAAGCCGACCCGTTCGCGCATGATGGAGTACGACCAGCCCCTGCTGTGGGTGGCGATCGTGCTGCTCGCGC
TCGGCCTGGTGATGGTCTACTCGGCGTCGATTGCGCTGCCGGATTCGCCGCGCTACGCCAACTATCGCGAAAGCCATTTC
CTGGTCCGCCATGCGTTCGCGCTGCTGATCGGGCTGTCGGTCGGCCTGGCGGCGTTCCAGATTCCCGTGAAGGTGTGGGA
CCGATACGCGCCCAAGCTGTTCATCATCGCGCTGGTGCTGCTGGTGATCGTGCTGGTGCCGTTCGTCGGCAAGGGCGTGA
ATGGCGCGCGCCGCTGGATTCCCCTCGGCATCATGAACTTCCAGCCGTCGGAGCTGATGAAGCTGGCCGTGGTGCTGTAC
GCGGCCAACTACACCGTGCGCAAGCAGGAGTGGATGCAGACCGTGTCCAAGGGCTTCCTGCCAATGGGTGTGGCGGTCGT
GGTGGTCGGCATGCTGCTGCTGCTCGAGCCGGACATGGGCGCGTTCCTCGTGATCGCCGCGGTGGCCATGGGCATTCTGT
TCCTTGGCGGCATCAACGGCAAGCTGTTCGCGGGACTGGTCGGTGTGGCGGTCGGCGCGTTTGCGCTGCTGATCACGGCA
TCGCCATGGCGGCGTGAACGGATCTTTGCATACCTCAATCCGTGGGAAGAGAGCAACGCGCTCGGCAAGGCGTACCAGTT
GACCCACTCGCTGATCGCGTTTGGCCGTGGCGAATGGACCGGTGTCGGCCTTGGCGGCAGCATCGAAAAATTGCACTACC
TGCCTGAAGCGCATACCGACTTCATCCTCGCCGTGATTGGCGAGGAATTTGGCTTTGTGGGCGTGCTGGTCGTCATCATC
CTGTTCTACTGGATGGTGCGCCGCGCGTTCGGCATCGGCCGCACCGCGCTGCAACTCGACCGCACGTTTGCCGGCCTCGT
GGCCAAGGGCATTGGCGTGTGGATCGGCTGGCAGACCTTTATCAATATGGGCGTGAACCTGGGCCTGCTGCCGACCAAGG
GATTGACGCTGCCGCTGGTGAGCTATGGCGGCTCGGGCATTCTGATGAATTGCATGGCTTTGGCGATCCTGCTCCGTATC
GACTATGAAAACCGTGTGCTGATGCGTGGAGGGAAGGTATGA

Upstream 100 bases:

>100_bases
CGGCCTGCGCCAGCCTCGACATGTTCCGTAACTACGTGCACCGCGCCGAAGTGTTCCGCTCGGCGGTGGAAGAACTGGCC
CTGTCGCGGGGGATCATGCC

Downstream 100 bases:

>100_bases
CGCAGCAGCGCACGTTGCTCGTGATGGCCGGCGGCACCGGGGGGCATGTATTCCCCGGGTTGGCGGTCGCGCACGCGCTG
CGCGAGCAGGGCTGGAAGGT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSESQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLALGLVMVYSASIALPDSPRYANYRESHF
LVRHAFALLIGLSVGLAAFQIPVKVWDRYAPKLFIIALVLLVIVLVPFVGKGVNGARRWIPLGIMNFQPSELMKLAVVLY
AANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFVGVLVVII
LFYWMVRRAFGIGRTALQLDRTFAGLVAKGIGVWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCMALAILLRI
DYENRVLMRGGKV

Sequences:

>Translated_413_residues
MSESQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLALGLVMVYSASIALPDSPRYANYRESHF
LVRHAFALLIGLSVGLAAFQIPVKVWDRYAPKLFIIALVLLVIVLVPFVGKGVNGARRWIPLGIMNFQPSELMKLAVVLY
AANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFVGVLVVII
LFYWMVRRAFGIGRTALQLDRTFAGLVAKGIGVWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCMALAILLRI
DYENRVLMRGGKV
>Mature_412_residues
SESQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLALGLVMVYSASIALPDSPRYANYRESHFL
VRHAFALLIGLSVGLAAFQIPVKVWDRYAPKLFIIALVLLVIVLVPFVGKGVNGARRWIPLGIMNFQPSELMKLAVVLYA
ANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITAS
PWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFVGVLVVIIL
FYWMVRRAFGIGRTALQLDRTFAGLVAKGIGVWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCMALAILLRID
YENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=45.5263157894737, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1786853, Length=328, Percent_Identity=35.3658536585366, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45001; Mature: 44870

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLALGLVMVY
CCCHHHHHCCCCEEEHHHHHCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SASIALPDSPRYANYRESHFLVRHAFALLIGLSVGLAAFQIPVKVWDRYAPKLFIIALVL
HCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LVIVLVPFVGKGVNGARRWIPLGIMNFQPSELMKLAVVLYAANYTVRKQEWMQTVSKGFL
HHHHHHHHHCCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
CCCHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
FILAVIGEEFGFVGVLVVIILFYWMVRRAFGIGRTALQLDRTFAGLVAKGIGVWIGWQTF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECHHHH
INMGVNLGLLPTKGLTLPLVSYGGSGILMNCMALAILLRIDYENRVLMRGGKV
HHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
SESQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLALGLVMVY
CCHHHHHCCCCEEEHHHHHCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SASIALPDSPRYANYRESHFLVRHAFALLIGLSVGLAAFQIPVKVWDRYAPKLFIIALVL
HCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LVIVLVPFVGKGVNGARRWIPLGIMNFQPSELMKLAVVLYAANYTVRKQEWMQTVSKGFL
HHHHHHHHHCCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
CCCHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
FILAVIGEEFGFVGVLVVIILFYWMVRRAFGIGRTALQLDRTFAGLVAKGIGVWIGWQTF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECHHHH
INMGVNLGLLPTKGLTLPLVSYGGSGILMNCMALAILLRIDYENRVLMRGGKV
HHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]