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The map label for this gene is argJ

Identifier: 73542653

GI number: 73542653

Start: 3254689

End: 3255915

Strand: Reverse

Name: argJ

Synonym: Reut_A2969

Alternate gene names: 73542653

Gene position: 3255915-3254689 (Counterclockwise)

Preceding gene: 73542654

Following gene: 73542652

Centisome position: 85.53

GC content: 66.99

Gene sequence:

>1227_bases
ATGCCCGTCAATCTTCCGCTGCCGCAGGCAGACAACCTGAAACCCGTTGCCGGCGTGGAGCTCGGCTGGGCCGAGGCCGG
CATCCGCAAGGCCAACCGCAAGGACGTGCTTGTCGTGCGCGTGGCCGAAGGCAGCACGGTGGCTGGCGTGTTTACGCGCA
ACCGCTTCTGCGCCGCGCCGGTGCAGGTTTGCCGCGAGAACCTTGCTGGCGGAAAGGGTATTCGCGCGCTGGTGATCAAC
ACTGGCAACGCCAATGCCGGGACCGGCGAGACCGGCCTGGCCAATGCGCGTGCCACATGTGACGCGCTGGCTGGCCAACT
GGGCATCGCCGCGAATCAGGTGCTGCCGTTCTCGACCGGCGTGATCCTCGAACAACTGCCGATGGACCGGCTGCTCGCCG
GCCTGGCACCGGCCATCGCCAACGCCAAGGCTGACAACTGGCTGGCCGCAGCGGAATCGATCATGACCACCGACACGCAG
CCCAAGGCGGCGTCGCGCACGGTACAGATCGACGGCAAGACGGTCACGCTGAGCGGTATCAGCAAGGGCGCTGGCATGAT
CCGCCCGAACATGGCGACCATGCTCGGCTTCATCGCCACCGACGCGGCCGTGGCCCAGCCGGTGCTACAGGCGCTGGTGT
CGCATGCGGCCGACCACTCGTTCAACAGCATCACGATCGACGGCGATACGTCGACCAACGATTCTTTCGTGCTGATCGCC
ACGGGCAAGTCGGGCGCCGCGATCGACCGCGCCGACGGCCCGGCCTTCGAAGCGCTGCGCGAGGCCGTGACCAGCCTGGC
CCAGGAACTCGCGCAGATGATCGTGCGCGACGGCGAGGGCGCCACCAAGCTGATGACCATCCGCGTGGAAGGCGGCAAGG
ACGTGGCTGAATGCCGCCAGATCGCTTATGCCGTGGCCCACTCGCCGCTGGTCAAGACCGCGTTCTACGCTTCGGACCCC
AACCTCGGCCGTATCCTGGCCGCAGTCGGCTACGCCGGTGTGGATGATCTCGATGTCGACCGCGTCAACCTGTGGCTTGA
CGACGTCTGGGTCGCGCGCGACGGCGGCCGCAACCCCGAATACCGGGAAGAAGACGGCCAGCGCGTGATGAAGCAGGCCG
AAATCACCGTGCGCATCGCGCTGGGCCGCGGCAACGCCGAGGCCACGGTGTGGACCTGCGACCTCTCGCACGACTACGTA
TCGATCAACGCGGACTACCGTTCCTGA

Upstream 100 bases:

>100_bases
GAAGAGATAACGACATGCCCGCGCTACGCGGGCATGTTCGTCTGACGACTGAACAGAATCAGGTCAAGCAGGACCACAGG
ACTACAGGACAGGAGCCGAT

Downstream 100 bases:

>100_bases
TCATCGCCCCCTGTTCAACGACGCTCTGCTGCCATGTCTGACCTCGCCTCTCGCCTCGACAATTTCCTCGCCCGACTCGA
ACAGTGGCTACCGCCGCAGC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MPVNLPLPQADNLKPVAGVELGWAEAGIRKANRKDVLVVRVAEGSTVAGVFTRNRFCAAPVQVCRENLAGGKGIRALVIN
TGNANAGTGETGLANARATCDALAGQLGIAANQVLPFSTGVILEQLPMDRLLAGLAPAIANAKADNWLAAAESIMTTDTQ
PKAASRTVQIDGKTVTLSGISKGAGMIRPNMATMLGFIATDAAVAQPVLQALVSHAADHSFNSITIDGDTSTNDSFVLIA
TGKSGAAIDRADGPAFEALREAVTSLAQELAQMIVRDGEGATKLMTIRVEGGKDVAECRQIAYAVAHSPLVKTAFYASDP
NLGRILAAVGYAGVDDLDVDRVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGNAEATVWTCDLSHDYV
SINADYRS

Sequences:

>Translated_408_residues
MPVNLPLPQADNLKPVAGVELGWAEAGIRKANRKDVLVVRVAEGSTVAGVFTRNRFCAAPVQVCRENLAGGKGIRALVIN
TGNANAGTGETGLANARATCDALAGQLGIAANQVLPFSTGVILEQLPMDRLLAGLAPAIANAKADNWLAAAESIMTTDTQ
PKAASRTVQIDGKTVTLSGISKGAGMIRPNMATMLGFIATDAAVAQPVLQALVSHAADHSFNSITIDGDTSTNDSFVLIA
TGKSGAAIDRADGPAFEALREAVTSLAQELAQMIVRDGEGATKLMTIRVEGGKDVAECRQIAYAVAHSPLVKTAFYASDP
NLGRILAAVGYAGVDDLDVDRVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGNAEATVWTCDLSHDYV
SINADYRS
>Mature_407_residues
PVNLPLPQADNLKPVAGVELGWAEAGIRKANRKDVLVVRVAEGSTVAGVFTRNRFCAAPVQVCRENLAGGKGIRALVINT
GNANAGTGETGLANARATCDALAGQLGIAANQVLPFSTGVILEQLPMDRLLAGLAPAIANAKADNWLAAAESIMTTDTQP
KAASRTVQIDGKTVTLSGISKGAGMIRPNMATMLGFIATDAAVAQPVLQALVSHAADHSFNSITIDGDTSTNDSFVLIAT
GKSGAAIDRADGPAFEALREAVTSLAQELAQMIVRDGEGATKLMTIRVEGGKDVAECRQIAYAVAHSPLVKTAFYASDPN
LGRILAAVGYAGVDDLDVDRVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGNAEATVWTCDLSHDYVS
INADYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=412, Percent_Identity=39.5631067961165, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_CUPPJ (Q46X04)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_297173.1
- ProteinModelPortal:   Q46X04
- SMR:   Q46X04
- MEROPS:   T05.001
- GeneID:   3612366
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2969
- NMPDR:   fig|264198.3.peg.2919
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   REUT264198:REUT_A2969-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42834; Mature: 42703

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNLPLPQADNLKPVAGVELGWAEAGIRKANRKDVLVVRVAEGSTVAGVFTRNRFCAAP
CCCCCCCCCCCCCCCCCCCEECHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCHHH
VQVCRENLAGGKGIRALVINTGNANAGTGETGLANARATCDALAGQLGIAANQVLPFSTG
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
VILEQLPMDRLLAGLAPAIANAKADNWLAAAESIMTTDTQPKAASRTVQIDGKTVTLSGI
HHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECC
SKGAGMIRPNMATMLGFIATDAAVAQPVLQALVSHAADHSFNSITIDGDTSTNDSFVLIA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGKSGAAIDRADGPAFEALREAVTSLAQELAQMIVRDGEGATKLMTIRVEGGKDVAECRQ
ECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHH
IAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVDDLDVDRVNLWLDDVWVARDGGRNPE
HHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
YREEDGQRVMKQAEITVRIALGRGNAEATVWTCDLSHDYVSINADYRS
CCHHHHHHHHHHCEEEEEEEEECCCCCEEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure 
PVNLPLPQADNLKPVAGVELGWAEAGIRKANRKDVLVVRVAEGSTVAGVFTRNRFCAAP
CCCCCCCCCCCCCCCCCCEECHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCHHH
VQVCRENLAGGKGIRALVINTGNANAGTGETGLANARATCDALAGQLGIAANQVLPFSTG
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
VILEQLPMDRLLAGLAPAIANAKADNWLAAAESIMTTDTQPKAASRTVQIDGKTVTLSGI
HHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECC
SKGAGMIRPNMATMLGFIATDAAVAQPVLQALVSHAADHSFNSITIDGDTSTNDSFVLIA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGKSGAAIDRADGPAFEALREAVTSLAQELAQMIVRDGEGATKLMTIRVEGGKDVAECRQ
ECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHH
IAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVDDLDVDRVNLWLDDVWVARDGGRNPE
HHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
YREEDGQRVMKQAEITVRIALGRGNAEATVWTCDLSHDYVSINADYRS
CCHHHHHHHHHHCEEEEEEEEECCCCCEEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA