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The map label for this gene is obgE [H]

Identifier: 73542640

GI number: 73542640

Start: 3241649

End: 3242746

Strand: Reverse

Name: obgE [H]

Synonym: Reut_A2956

Alternate gene names: 73542640

Gene position: 3242746-3241649 (Counterclockwise)

Preceding gene: 73542641

Following gene: 73542639

Centisome position: 85.19

GC content: 65.21

Gene sequence:

>1098_bases
ATGAAGTTCATCGACGAAGCCCGAATCGAAGCCATCGCCGGCAACGGCGGCAATGGCAGCGCCTCGTTCCGGCGCGAGAA
GTTTGTGCCCTTCGGTGGTCCGGATGGCGGCGACGGCGGCCGGGGTGGCAGCGTGTTCGCCGTGGCGGACCGCAACATCA
ATACGCTGATCGACTTCCGCTACGCGAAGAAGCACGTGGCGCGCAACGGTGAAAACGGCCGTGGCTCCGACTGCTACGGT
GCGGCCGGCGACGACGTCACGTTGCGCATGCCGGTCGGTACGCTGATCACCGACATGGACACCGGCGAGCTGATCGCCGA
CCTGACCGAGCACGGCCAGAAGGTCTGCCTGGCCGAAGGCGGCATGGGTGGCTGGGGCAACCTGCATTTCAAGTCCAGTA
CCAACCGCGCGCCGCGCCAGCAGGTTGACGGCAAGCCGGGCGAGCGCCGCATGCTCAAGCTCGAACTCAAGGTGCTGGCC
GACGTCGGCCTGCTGGGCATGCCCAACGCCGGCAAGTCGACGTTCATCTCGCATATCTCGAACGCGCGGCCGAAGGTGGC
GGACTACCCGTTCACCACGCTGCACCCGAACCTGGGTGTGGTGCGCGTCGACCATGAGCAGTCTTTCGTGGTGGCCGACA
TTCCGGGCCTGATCGAAGGCGCGGCCGAAGGCGCTGGCCTCGGCCACCAGTTCCTGCGCCATCTGCAGCGTACGGGCCTG
TTGCTGCACATCGTTGACCTCGCGCCGTTTGATGAAGCCGTGGATCCCGTGGCGGAAGCCAAGGCCATCGTCAACGAGCT
CAAGAAGTACGACGAAACGCTCTACGACAAGCCGCGCTGGCTCGTGCTGAACAAGCTCGACGTAGTGCCCGAGGAAGAGC
GCGCCACGCGCGTGAAGGACTTCATCAAGCGCTACAAGTGGAAGGGCCCGGTGTTCCAGATCTCCGCGCTGACCGGCGAC
GGCTGCCGCGAGTTGATCTACGCGATCAAGGACCACCTGGCAGCGCTCAAGGCTGAAGAGGCCGCAGCGCTGGCCGAGCC
CGATATCCGCCTCGACGAGCGCCTGCATAACGTCGACCACGACGGTCACGAGCAGTAA

Upstream 100 bases:

>100_bases
GCCCCGCAACGCTTGCGGGGCTTTTTTGTTTCTGGCGACAATATAAATAGTCAATGCCAGTCACCCGCCCGGTCACCTGG
CTCCATCACGGAAACCCATC

Downstream 100 bases:

>100_bases
GCCAGCTTTTCTCCCTCGCCCATGCGGGGCGAGGGATCACCATTGGGGATGCCAGAAAAGCCCCCCGGAGACAGGATTTC
TCGCCATGCAATCGGTCATT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGDDVTLRMPVGTLITDMDTGELIADLTEHGQKVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHISNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERATRVKDFIKRYKWKGPVFQISALTGD
GCRELIYAIKDHLAALKAEEAAALAEPDIRLDERLHNVDHDGHEQ

Sequences:

>Translated_365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGDDVTLRMPVGTLITDMDTGELIADLTEHGQKVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHISNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERATRVKDFIKRYKWKGPVFQISALTGD
GCRELIYAIKDHLAALKAEEAAALAEPDIRLDERLHNVDHDGHEQ
>Mature_365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGDDVTLRMPVGTLITDMDTGELIADLTEHGQKVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHISNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERATRVKDFIKRYKWKGPVFQISALTGD
GCRELIYAIKDHLAALKAEEAAALAEPDIRLDERLHNVDHDGHEQ

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=328, Percent_Identity=39.6341463414634, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI111955139, Length=365, Percent_Identity=34.5205479452055, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI111955063, Length=199, Percent_Identity=36.1809045226131, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI58761500, Length=173, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4758796, Length=156, Percent_Identity=32.6923076923077, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789574, Length=344, Percent_Identity=55.5232558139535, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790615, Length=236, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=333, Percent_Identity=38.7387387387387, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=371, Percent_Identity=29.6495956873315, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=168, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321962, Length=208, Percent_Identity=38.9423076923077, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585318, Length=307, Percent_Identity=38.1107491856677, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20129375, Length=328, Percent_Identity=37.5, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24640873, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640877, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640875, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17981711, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39816; Mature: 39816

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFR
CCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
YAKKHVARNGENGRGSDCYGAAGDDVTLRMPVGTLITDMDTGELIADLTEHGQKVCLAEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCHHHHHHHHHCCCEEEEECC
GMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHIS
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
NARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERATRVKD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FIKRYKWKGPVFQISALTGDGCRELIYAIKDHLAALKAEEAAALAEPDIRLDERLHNVDH
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
DGHEQ
CCCCC
>Mature Secondary Structure
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFR
CCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
YAKKHVARNGENGRGSDCYGAAGDDVTLRMPVGTLITDMDTGELIADLTEHGQKVCLAEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCHHHHHHHHHCCCEEEEECC
GMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHIS
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
NARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERATRVKD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FIKRYKWKGPVFQISALTGDGCRELIYAIKDHLAALKAEEAAALAEPDIRLDERLHNVDH
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
DGHEQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA