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The map label for this gene is dgt [H]

Identifier: 73542623

GI number: 73542623

Start: 3220799

End: 3222214

Strand: Reverse

Name: dgt [H]

Synonym: Reut_A2939

Alternate gene names: 73542623

Gene position: 3222214-3220799 (Counterclockwise)

Preceding gene: 73542624

Following gene: 73542621

Centisome position: 84.65

GC content: 49.86

Gene sequence:

>1416_bases
ATGACCGGTCGTAATATTCTCACGGAGTCCGAGAGCGATAGGGGGCGCGTTCTGTTTTCTCCGGCGTTTCGACGTTTGCA
GCAAAAAGCCCAAGTTTTCTCTATGGAGCCAAATGCTGCGGTACGTAGCCGATTGACTCATTCGTTTGAGGTTTCCCAAA
TCGGTCGATACATTGCGGACCTATTGTCTGAGAAGCTCGGCATCGCGACGGAGCAGCAGGCTGGAGCGCTGGTGAACTTC
GTCGAAACCGCTTGCCTAATGCATGATATAGGCAATCCACCATTCGGACATTTTGGTGAAGAGGCCATCAAAAAATGGTT
TGAAGACAATGGGGAACGCTGTCTCCGCTTGTCCATCGGGAGGCCCAAGCCATCTGATGGAGCATGTCCCGATCAAGCCA
AGGTGCGTGATGCACTGGTGGACTTCGCTGATTTCGATGGTAACCCCCAAGGGTTGCGTATTGTGGCGCGCTTGCAGTGG
AACACAGACGAGTTTGGGCTTAACCTAACCAAGACGTCATTAGCATCATTTATGAAATATATCCGCATGGCGGGTGGGGA
AAAGTCGGGCATTTTCACAAAAAAAGCCGGCTATTTCACGACGGAAAGGGATTTAGTCGAATCCGTTTGGCGCGAATTTG
GTTACGAACTGCCTCAGCGCTTCCCCTTGGCGTATATCATGGAGGCGGCCGATGACATCGCCTACTGTATTAGTGATCTT
GAAGACTCCTTTGAAAAAGACATAGTTCGCCCCGATGATGCGCTGAGTTATGTTGAGGAGCAATACGAACGACATGAATT
CGAGGATGGTGATCCGAAGCATGTCGATATTCGCCGAGCTATTCGGCAGATGAGGGCGAAGGAGCGGGAGAGTGGAGGGG
AGTTTACTTTTACTGATTTTCGAACGTCATTAAATAACGTGATCGTTAATTATGTCGCTGATCGATACGTAGAAAATCAT
TCGAAGATTCTTGACGGAACCTTGGAGTCATTGATTCCTGGCAACGAACCACCTGGTGCGATTCTCAACGCAATTAGAAA
ATTCTGTCGAGAGCATGTGTATACTCACGAGTCGGTTCAACGTGTAGAGCTGGCGGGCTACAATGCCATTCGAGGTTTGC
TGGAGCAGTGCTCTTCGTTGCTTTGCATCTCCGCCGAAGGGTTTCGTGCGGCAAGAGCTAACGAGAAGCAGGATGCGAAA
GGCCAAGCGCTCGTTCTTGAACCAAAGCTGTTGAGGCTATTTCCAGAAAAATACATAAAGGTTTACGATTATCATCTGAA
GCAAGCAGGTGGTGACGAGGCGGACCCGTTCTTGGAGTGGACCTATCGGGCTCATCTGATCGTCGACTTTATTTCTGGCA
TGACTGACGATTTCGCCATGACGACTTACCGCACCTTGGCGGGGATGAGGCTTTAA

Upstream 100 bases:

>100_bases
TTATAGAGTCTTGTCTGAGTCTGGAAGAATAAGAAAAAGGAGGGAAAAATTGTTCGACTATCTAAATATCCTGAAAACGG
CGCGTCTTAGACCGTCGAAG

Downstream 100 bases:

>100_bases
GCTGTGATTCCAGTAAAGCACCCCTACTGGCATGTCCGGGCTGTCGTTGAGGCTCGGCCCGAGATAGAGGCCATTCCGCT
TAGCTATTACACATACAAGC

Product: deoxyguanosinetriphosphate triphosphohydrolase

Products: NA

Alternate protein names: dGTP triphosphohydrolase; dGTPase [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTGRNILTESESDRGRVLFSPAFRRLQQKAQVFSMEPNAAVRSRLTHSFEVSQIGRYIADLLSEKLGIATEQQAGALVNF
VETACLMHDIGNPPFGHFGEEAIKKWFEDNGERCLRLSIGRPKPSDGACPDQAKVRDALVDFADFDGNPQGLRIVARLQW
NTDEFGLNLTKTSLASFMKYIRMAGGEKSGIFTKKAGYFTTERDLVESVWREFGYELPQRFPLAYIMEAADDIAYCISDL
EDSFEKDIVRPDDALSYVEEQYERHEFEDGDPKHVDIRRAIRQMRAKERESGGEFTFTDFRTSLNNVIVNYVADRYVENH
SKILDGTLESLIPGNEPPGAILNAIRKFCREHVYTHESVQRVELAGYNAIRGLLEQCSSLLCISAEGFRAARANEKQDAK
GQALVLEPKLLRLFPEKYIKVYDYHLKQAGGDEADPFLEWTYRAHLIVDFISGMTDDFAMTTYRTLAGMRL

Sequences:

>Translated_471_residues
MTGRNILTESESDRGRVLFSPAFRRLQQKAQVFSMEPNAAVRSRLTHSFEVSQIGRYIADLLSEKLGIATEQQAGALVNF
VETACLMHDIGNPPFGHFGEEAIKKWFEDNGERCLRLSIGRPKPSDGACPDQAKVRDALVDFADFDGNPQGLRIVARLQW
NTDEFGLNLTKTSLASFMKYIRMAGGEKSGIFTKKAGYFTTERDLVESVWREFGYELPQRFPLAYIMEAADDIAYCISDL
EDSFEKDIVRPDDALSYVEEQYERHEFEDGDPKHVDIRRAIRQMRAKERESGGEFTFTDFRTSLNNVIVNYVADRYVENH
SKILDGTLESLIPGNEPPGAILNAIRKFCREHVYTHESVQRVELAGYNAIRGLLEQCSSLLCISAEGFRAARANEKQDAK
GQALVLEPKLLRLFPEKYIKVYDYHLKQAGGDEADPFLEWTYRAHLIVDFISGMTDDFAMTTYRTLAGMRL
>Mature_470_residues
TGRNILTESESDRGRVLFSPAFRRLQQKAQVFSMEPNAAVRSRLTHSFEVSQIGRYIADLLSEKLGIATEQQAGALVNFV
ETACLMHDIGNPPFGHFGEEAIKKWFEDNGERCLRLSIGRPKPSDGACPDQAKVRDALVDFADFDGNPQGLRIVARLQWN
TDEFGLNLTKTSLASFMKYIRMAGGEKSGIFTKKAGYFTTERDLVESVWREFGYELPQRFPLAYIMEAADDIAYCISDLE
DSFEKDIVRPDDALSYVEEQYERHEFEDGDPKHVDIRRAIRQMRAKERESGGEFTFTDFRTSLNNVIVNYVADRYVENHS
KILDGTLESLIPGNEPPGAILNAIRKFCREHVYTHESVQRVELAGYNAIRGLLEQCSSLLCISAEGFRAARANEKQDAKG
QALVLEPKLLRLFPEKYIKVYDYHLKQAGGDEADPFLEWTYRAHLIVDFISGMTDDFAMTTYRTLAGMRL

Specific function: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs [H]

COG id: COG0232

COG function: function code F; dGTP triphosphohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dGTPase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786355, Length=493, Percent_Identity=36.5111561866126, Blast_Score=275, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006261
- InterPro:   IPR020779
- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: =3.1.5.1 [H]

Molecular weight: Translated: 53502; Mature: 53371

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRNILTESESDRGRVLFSPAFRRLQQKAQVFSMEPNAAVRSRLTHSFEVSQIGRYIAD
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLSEKLGIATEQQAGALVNFVETACLMHDIGNPPFGHFGEEAIKKWFEDNGERCLRLSIG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
RPKPSDGACPDQAKVRDALVDFADFDGNPQGLRIVARLQWNTDEFGLNLTKTSLASFMKY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHCCCHHHHHHHHHHHH
IRMAGGEKSGIFTKKAGYFTTERDLVESVWREFGYELPQRFPLAYIMEAADDIAYCISDL
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCHHCHHHCCHHHHHHHHHHHHHHHHHH
EDSFEKDIVRPDDALSYVEEQYERHEFEDGDPKHVDIRRAIRQMRAKERESGGEFTFTDF
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHH
RTSLNNVIVNYVADRYVENHSKILDGTLESLIPGNEPPGAILNAIRKFCREHVYTHESVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVELAGYNAIRGLLEQCSSLLCISAEGFRAARANEKQDAKGQALVLEPKLLRLFPEKYIK
HHHHHCHHHHHHHHHHHHHEEEECCCCCHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHH
VYDYHLKQAGGDEADPFLEWTYRAHLIVDFISGMTDDFAMTTYRTLAGMRL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGRNILTESESDRGRVLFSPAFRRLQQKAQVFSMEPNAAVRSRLTHSFEVSQIGRYIAD
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLSEKLGIATEQQAGALVNFVETACLMHDIGNPPFGHFGEEAIKKWFEDNGERCLRLSIG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
RPKPSDGACPDQAKVRDALVDFADFDGNPQGLRIVARLQWNTDEFGLNLTKTSLASFMKY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHCCCHHHHHHHHHHHH
IRMAGGEKSGIFTKKAGYFTTERDLVESVWREFGYELPQRFPLAYIMEAADDIAYCISDL
HHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCHHCHHHCCHHHHHHHHHHHHHHHHHH
EDSFEKDIVRPDDALSYVEEQYERHEFEDGDPKHVDIRRAIRQMRAKERESGGEFTFTDF
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHH
RTSLNNVIVNYVADRYVENHSKILDGTLESLIPGNEPPGAILNAIRKFCREHVYTHESVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVELAGYNAIRGLLEQCSSLLCISAEGFRAARANEKQDAKGQALVLEPKLLRLFPEKYIK
HHHHHCHHHHHHHHHHHHHEEEECCCCCHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHH
VYDYHLKQAGGDEADPFLEWTYRAHLIVDFISGMTDDFAMTTYRTLAGMRL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]