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The map label for this gene is dgk [H]

Identifier: 73542464

GI number: 73542464

Start: 3047937

End: 3048581

Strand: Direct

Name: dgk [H]

Synonym: Reut_A2779

Alternate gene names: 73542464

Gene position: 3047937-3048581 (Clockwise)

Preceding gene: 73542463

Following gene: 73542465

Centisome position: 80.07

GC content: 65.12

Gene sequence:

>645_bases
ATGCTCGAACACCTGCGCCGCATCGTCGTGGAAGGCCCGGTCGGGTCCGGCAAGACTTCGCTGGCCCAGCGCCTTGCGCA
CACGCTGCACGCGGCCGAACTCCCCGACGGCGTCCGCAGCAACCCCTTCCTCGAACGCTTCTACCGCGATCGCGCGCGCT
ATGCGCTGCCGCTGCAACTGGCCTGCCTGAACAAGCGTGCCGACCAGCTCCAGCAATGGCAAAACGCCCTGTTCGCAGGG
CAGCGCATGGTCAGCAATTTCCTGATCGCAAAGGATCGCCTGTACGCTTCGCTGAACCTGCCCGAGGACGAGCTGGCACT
CTATGACGCGATTGCCTCACGGCTGCAGTTGCCACCACAGCGCACCGACCTCGTGATCATGCTGCAGGCCACCCCGTCGC
TGCTGCGCGAGCGCATCGCCCGCCGTGGCGAGCCCGGCGAGGCTGCCGGCATCGACGAGGCCTACCTGCAGCAGCTGACG
GACGCCTACGGCGAACTGTTCCATCGCTATGACGAAGCCCCCGTACTGATCGTGGATACGGCCCACTTCAATCCGGTGGA
CAACGATGGGGATTTCCGTACACTACTGACGCGCATCGAGAACATGCGCGGCCGCAGGGCCTTTCTCAATCTGGCTGCGC
CCTGA

Upstream 100 bases:

>100_bases
CCACCTGCAAGTGCATGCGCGCGCAGGCCGCCGGTTCAGCCGGCCCCTCCGACGCTAAGGACTGAGCCGGCGGAGCCATC
CGCCTCGCGCCGGCAACGAT

Downstream 100 bases:

>100_bases
CCGCAGCGGGCTTGCCCGCGACGGCACACAACCATAACGACAGCCGCGCCGGCCCGCCTCACGCCGAGCGCCCTCTCCTG
ACTCGTCACTGCCATGAGCT

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MLEHLRRIVVEGPVGSGKTSLAQRLAHTLHAAELPDGVRSNPFLERFYRDRARYALPLQLACLNKRADQLQQWQNALFAG
QRMVSNFLIAKDRLYASLNLPEDELALYDAIASRLQLPPQRTDLVIMLQATPSLLRERIARRGEPGEAAGIDEAYLQQLT
DAYGELFHRYDEAPVLIVDTAHFNPVDNDGDFRTLLTRIENMRGRRAFLNLAAP

Sequences:

>Translated_214_residues
MLEHLRRIVVEGPVGSGKTSLAQRLAHTLHAAELPDGVRSNPFLERFYRDRARYALPLQLACLNKRADQLQQWQNALFAG
QRMVSNFLIAKDRLYASLNLPEDELALYDAIASRLQLPPQRTDLVIMLQATPSLLRERIARRGEPGEAAGIDEAYLQQLT
DAYGELFHRYDEAPVLIVDTAHFNPVDNDGDFRTLLTRIENMRGRRAFLNLAAP
>Mature_214_residues
MLEHLRRIVVEGPVGSGKTSLAQRLAHTLHAAELPDGVRSNPFLERFYRDRARYALPLQLACLNKRADQLQQWQNALFAG
QRMVSNFLIAKDRLYASLNLPEDELALYDAIASRLQLPPQRTDLVIMLQATPSLLRERIARRGEPGEAAGIDEAYLQQLT
DAYGELFHRYDEAPVLIVDTAHFNPVDNDGDFRTLLTRIENMRGRRAFLNLAAP

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24260; Mature: 24260

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEHLRRIVVEGPVGSGKTSLAQRLAHTLHAAELPDGVRSNPFLERFYRDRARYALPLQL
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHH
ACLNKRADQLQQWQNALFAGQRMVSNFLIAKDRLYASLNLPEDELALYDAIASRLQLPPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCC
RTDLVIMLQATPSLLRERIARRGEPGEAAGIDEAYLQQLTDAYGELFHRYDEAPVLIVDT
CCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AHFNPVDNDGDFRTLLTRIENMRGRRAFLNLAAP
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure
MLEHLRRIVVEGPVGSGKTSLAQRLAHTLHAAELPDGVRSNPFLERFYRDRARYALPLQL
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHH
ACLNKRADQLQQWQNALFAGQRMVSNFLIAKDRLYASLNLPEDELALYDAIASRLQLPPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCC
RTDLVIMLQATPSLLRERIARRGEPGEAAGIDEAYLQQLTDAYGELFHRYDEAPVLIVDT
CCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AHFNPVDNDGDFRTLLTRIENMRGRRAFLNLAAP
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]