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The map label for this gene is argD [H]

Identifier: 73542408

GI number: 73542408

Start: 2990055

End: 2991242

Strand: Direct

Name: argD [H]

Synonym: Reut_A2723

Alternate gene names: 73542408

Gene position: 2990055-2991242 (Clockwise)

Preceding gene: 73542407

Following gene: 73542417

Centisome position: 78.55

GC content: 64.73

Gene sequence:

>1188_bases
ATGGCATTTGCTGAGTATCCCGTTCAATCCCTGATGTACATCACCAACCGGCCCGAACTCGTGTTCACCGAGGGCAAGGG
CTCCTGGCTGACGGACCATAACGGCAAGCGATACCTGGACTTCGTGCAAGGCTGGGCAGTGAACTGCCTCGGCCACTCCA
ACCAGGGCATGGTCGACGCCGTGGTCGCGCAGGCCGGCAAGCTGATCAACCCGAGCCCGGCTTTCTACAACGCGCCGATG
ATCAAGCTGGCCAAGCAGCTCACCGACAACAGCTGCTTCGACAAGGTCTTCTTCGCCAACAGCGGCGCCGAAGCCAACGA
AGGCGCAATCAAGCTCGCGCGCAAATGGGGCCGCAAGCACAAGAACGGCGCGTTCGAGATCATCACCATGGACCACAGTT
TCCATGGCCGCACGCTCGCCACCATGAGCGCGTCGGGCAAGGCTGGCTGGGACACCATCTTCGCGCCGCAGGTGCCCGGC
TTCCCGAAGGCCGACCTGAACGACCTGGCCTCGGTGGAAAAGCTGATCACCGACAAGACCGTCGGCATCATGCTCGAGCC
GGTGCAGGGCGAAGGCGGCGTGCTTCCCGCCACGCGCGAGTTCATGCAGGGCCTGCGCGCGCTGGCCGACAAGCACAAGC
TGCTGCTGATCGTCGATGAAGTGCAGACCGGTTGCGGCCGCTGCGGCACGCTGTTCGCGTACGAGCTGTCGGGCGTGGAG
CCGGACATCATGACGCTGGGCAAGGGCATCGGCGGTGGCGTGCCGCTGTCGGCGCTGCTGTGCAAGGCTGAAGTCGCGAG
CTTCGAGGCCGGCGACCAGGGCGGCACCTACAATGGCAACCCGCTGATGACCGCGGTCGGCAGCGCCGTCATCGAGCAAC
TGACCGCACCGGGGTTCCTGGACGATGTGAAAGCCAAGGGCGAGTACCTGAAGGAACAGCTGCTGGCCCTGTGCAGCGAA
TTTGGCCTGGCCGGCGAGCGCGGAGAAGGCCTGCTGCGTGCCCTGCAACTCGGCAAGGACATCGGCCCGCAGCTGGTCGA
GGAAGCGCGCGACATGGGACCCGACGGCCTGCTGCTGAATGCGCCGCGCGCCAACCTGCTGCGCTTCATGCCGGCACTGA
ACGTGACGCGTGAAGAGATCGACCAGATGATCGGGATGCTGCGTACGCTGCTGAAGAAGCTGGCCTGA

Upstream 100 bases:

>100_bases
TCATGTCAACGAGCCACGGGCAACCCCCGTGGCTTTTTGTTTTTGTTCCGGCCCTTCCGCCCGTCCGTCCATCATTCAAA
GCCGACCCCTGGAGTCCGCC

Downstream 100 bases:

>100_bases
TCGTCAGACGAAACGGGCCCTGAACGGGCCCTCTGCCTGCCATCGGGGAGGCGGGACGGGGCACCCCGCGCCCCGTCCCC
CAGCACAGGTCACCGCGCCC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAFAEYPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNCLGHSNQGMVDAVVAQAGKLINPSPAFYNAPM
IKLAKQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAFEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPG
FPKADLNDLASVEKLITDKTVGIMLEPVQGEGGVLPATREFMQGLRALADKHKLLLIVDEVQTGCGRCGTLFAYELSGVE
PDIMTLGKGIGGGVPLSALLCKAEVASFEAGDQGGTYNGNPLMTAVGSAVIEQLTAPGFLDDVKAKGEYLKEQLLALCSE
FGLAGERGEGLLRALQLGKDIGPQLVEEARDMGPDGLLLNAPRANLLRFMPALNVTREEIDQMIGMLRTLLKKLA

Sequences:

>Translated_395_residues
MAFAEYPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNCLGHSNQGMVDAVVAQAGKLINPSPAFYNAPM
IKLAKQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAFEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPG
FPKADLNDLASVEKLITDKTVGIMLEPVQGEGGVLPATREFMQGLRALADKHKLLLIVDEVQTGCGRCGTLFAYELSGVE
PDIMTLGKGIGGGVPLSALLCKAEVASFEAGDQGGTYNGNPLMTAVGSAVIEQLTAPGFLDDVKAKGEYLKEQLLALCSE
FGLAGERGEGLLRALQLGKDIGPQLVEEARDMGPDGLLLNAPRANLLRFMPALNVTREEIDQMIGMLRTLLKKLA
>Mature_394_residues
AFAEYPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNCLGHSNQGMVDAVVAQAGKLINPSPAFYNAPMI
KLAKQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKHKNGAFEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGF
PKADLNDLASVEKLITDKTVGIMLEPVQGEGGVLPATREFMQGLRALADKHKLLLIVDEVQTGCGRCGTLFAYELSGVEP
DIMTLGKGIGGGVPLSALLCKAEVASFEAGDQGGTYNGNPLMTAVGSAVIEQLTAPGFLDDVKAKGEYLKEQLLALCSEF
GLAGERGEGLLRALQLGKDIGPQLVEEARDMGPDGLLLNAPRANLLRFMPALNVTREEIDQMIGMLRTLLKKLA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=375, Percent_Identity=33.8666666666667, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=34.4481605351171, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=27.6346604215457, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=30.2211302211302, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=29.7297297297297, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=30.0518134715026, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=25.9708737864078, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI188536080, Length=409, Percent_Identity=24.4498777506112, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=409, Percent_Identity=24.4498777506112, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=409, Percent_Identity=24.4498777506112, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788044, Length=364, Percent_Identity=43.4065934065934, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=40.2116402116402, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1789016, Length=384, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=32.03125, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=33.033033033033, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=32.0099255583127, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786991, Length=323, Percent_Identity=29.7213622291022, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=369, Percent_Identity=34.1463414634146, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=28.2051282051282, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI25144274, Length=259, Percent_Identity=35.1351351351351, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=27.5058275058275, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71981843, Length=181, Percent_Identity=29.2817679558011, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=25.0569476082005, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=33.3333333333333, Blast_Score=209, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=383, Percent_Identity=33.9425587467363, Blast_Score=175, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=23.1308411214953, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=419, Percent_Identity=24.1050119331742, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.8624338624339, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=26.5700483091787, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=27.0731707317073, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=26.5258215962441, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366494, Length=298, Percent_Identity=26.510067114094, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667139, Length=298, Percent_Identity=26.510067114094, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667143, Length=298, Percent_Identity=26.510067114094, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42475; Mature: 42343

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFAEYPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNCLGHSNQGMVDA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCHHEEEECCCCCCHHHH
VVAQAGKLINPSPAFYNAPMIKLAKQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKH
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCC
KNGAFEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGFPKADLNDLASVEKLITDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCC
VGIMLEPVQGEGGVLPATREFMQGLRALADKHKLLLIVDEVQTGCGRCGTLFAYELSGVE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLSALLCKAEVASFEAGDQGGTYNGNPLMTAVGSAVIEQLTAPGFL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DDVKAKGEYLKEQLLALCSEFGLAGERGEGLLRALQLGKDIGPQLVEEARDMGPDGLLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
APRANLLRFMPALNVTREEIDQMIGMLRTLLKKLA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AFAEYPVQSLMYITNRPELVFTEGKGSWLTDHNGKRYLDFVQGWAVNCLGHSNQGMVDA
CCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCHHEEEECCCCCCHHHH
VVAQAGKLINPSPAFYNAPMIKLAKQLTDNSCFDKVFFANSGAEANEGAIKLARKWGRKH
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCC
KNGAFEIITMDHSFHGRTLATMSASGKAGWDTIFAPQVPGFPKADLNDLASVEKLITDKT
CCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCC
VGIMLEPVQGEGGVLPATREFMQGLRALADKHKLLLIVDEVQTGCGRCGTLFAYELSGVE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEEEECCCC
PDIMTLGKGIGGGVPLSALLCKAEVASFEAGDQGGTYNGNPLMTAVGSAVIEQLTAPGFL
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DDVKAKGEYLKEQLLALCSEFGLAGERGEGLLRALQLGKDIGPQLVEEARDMGPDGLLLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
APRANLLRFMPALNVTREEIDQMIGMLRTLLKKLA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]