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The map label for this gene is yesM [H]

Identifier: 73541654

GI number: 73541654

Start: 2152145

End: 2153314

Strand: Reverse

Name: yesM [H]

Synonym: Reut_A1966

Alternate gene names: 73541654

Gene position: 2153314-2152145 (Counterclockwise)

Preceding gene: 73541655

Following gene: 73541653

Centisome position: 56.57

GC content: 64.44

Gene sequence:

>1170_bases
ATGAACGCCATGGAACGCTGCATCTCCGCTGCCATCCCGTCCCGGCTGACAATCCTTGGGCGTGACCTGCTCTTTGTGCT
TTGCATGAACACGGTGATCGCGGTCAGCCTGAACTACGGCTTCCAGACCGGAGGCACGCTGTGGCACAACTTTGTCTACA
GCCACCTGATCGGCATATCGATCTGGATGCTGATCGATATTCCGCGCGTGATGATTTGGTGGAACGATCGCCCGCGCCGC
TGGCCGTTCCTGTTCCTGGCCGCGGCAGCCGTGCCTATGGGCGTGGTTCTGGGCAGCTGGGCCACGCGCGAGGTACTGAA
CCTGCCGCCAAAGCTGTCCGCTGAAACCGGCGATATGCTGCGCATGTGCCTGGTGGTGGGCATGCTGGCGTCCGCCAGCA
TGATCTATTTCTACTGGTCACGCGAAAAGCTGGCTTATCTCGAACGCCAGGCCGCGCTGGACGCCCTCCAGCGCGAAGAA
GCCGAGAAGCAACTCGTGCGCGCTCAGCTGATGGCACTCCAGGCACAGATCGAACCGCATTTCCTGTTCAACTCGCTGGC
CAATCTCGACGGGCTCATTGCCACGGACCCGCGCGCGGCACGCAAGCTGCTGCAACGGCTGATCGGCTTCCTGCGCACCT
CGCTGTCGCATACGCGGGCCGAGCAATGCACGCTGCGCCAGGAGTTCGAGTTGCTGCGCAGCTATCTCGATATCCAGGGC
ATGCGCTTCGGCACGCGCCTTGGCTACGACTTCGACCTGCCTGCCGAGCTGGCCGGTGTGGAGATTCCGCCGATGCTGAT
CCAGCCGCTGGTGGAGAATGCGGTCACGCATGGCATCGAGCCGTGCATGCGAGGTGGCCACATTACGCTGTCGGCGCGCG
CGGCTGGCGAAGACGCGGTACAGGTCATCATCGCCGATACCGGCGTCGGCTTCGGCCATGGATCGGGCAAGGGCTCTGGC
CTCGGCCTGACCCACGTGCGCGAACGGCTCGCGCGCATCTTTGGCGCGGCGGCCAGCATGCAGATGGAAGAAAACACGCC
GCGCGGCGTGGTCGTGCGTCTGACGCTGCCGATGACTCGCCATACCGAAGTGCCAATGCCGGCGCCGGCTGCTCCTCCGG
TGCCCGCCACGCCTGCCGGTGCTACACCGGCCATGCCTCGCCTCGGATGA

Upstream 100 bases:

>100_bases
GACAAGTGAGAGAGAGACATGAGGACGGGTGGCTTACGCGGGGCAAGAACCGTATGCTTGCGGACTACCACACATTGCGC
CAGGCATAGGGCACGCTAAC

Downstream 100 bases:

>100_bases
TCTGAAACGCCCTGCCTGCTGACATCGATCACGCCCCTGATCCCTGCCATGACTCCGACCCTGCTGATTGCCGATGATGA
ACCCCTGCTGGCCCGCGTGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNAMERCISAAIPSRLTILGRDLLFVLCMNTVIAVSLNYGFQTGGTLWHNFVYSHLIGISIWMLIDIPRVMIWWNDRPRR
WPFLFLAAAAVPMGVVLGSWATREVLNLPPKLSAETGDMLRMCLVVGMLASASMIYFYWSREKLAYLERQAALDALQREE
AEKQLVRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARKLLQRLIGFLRTSLSHTRAEQCTLRQEFELLRSYLDIQG
MRFGTRLGYDFDLPAELAGVEIPPMLIQPLVENAVTHGIEPCMRGGHITLSARAAGEDAVQVIIADTGVGFGHGSGKGSG
LGLTHVRERLARIFGAAASMQMEENTPRGVVVRLTLPMTRHTEVPMPAPAAPPVPATPAGATPAMPRLG

Sequences:

>Translated_389_residues
MNAMERCISAAIPSRLTILGRDLLFVLCMNTVIAVSLNYGFQTGGTLWHNFVYSHLIGISIWMLIDIPRVMIWWNDRPRR
WPFLFLAAAAVPMGVVLGSWATREVLNLPPKLSAETGDMLRMCLVVGMLASASMIYFYWSREKLAYLERQAALDALQREE
AEKQLVRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARKLLQRLIGFLRTSLSHTRAEQCTLRQEFELLRSYLDIQG
MRFGTRLGYDFDLPAELAGVEIPPMLIQPLVENAVTHGIEPCMRGGHITLSARAAGEDAVQVIIADTGVGFGHGSGKGSG
LGLTHVRERLARIFGAAASMQMEENTPRGVVVRLTLPMTRHTEVPMPAPAAPPVPATPAGATPAMPRLG
>Mature_389_residues
MNAMERCISAAIPSRLTILGRDLLFVLCMNTVIAVSLNYGFQTGGTLWHNFVYSHLIGISIWMLIDIPRVMIWWNDRPRR
WPFLFLAAAAVPMGVVLGSWATREVLNLPPKLSAETGDMLRMCLVVGMLASASMIYFYWSREKLAYLERQAALDALQREE
AEKQLVRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARKLLQRLIGFLRTSLSHTRAEQCTLRQEFELLRSYLDIQG
MRFGTRLGYDFDLPAELAGVEIPPMLIQPLVENAVTHGIEPCMRGGHITLSARAAGEDAVQVIIADTGVGFGHGSGKGSG
LGLTHVRERLARIFGAAASMQMEENTPRGVVVRLTLPMTRHTEVPMPAPAAPPVPATPAGATPAMPRLG

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=226, Percent_Identity=30.9734513274336, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788446, Length=185, Percent_Identity=34.5945945945946, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42819; Mature: 42819

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMERCISAAIPSRLTILGRDLLFVLCMNTVIAVSLNYGFQTGGTLWHNFVYSHLIGIS
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
IWMLIDIPRVMIWWNDRPRRWPFLFLAAAAVPMGVVLGSWATREVLNLPPKLSAETGDML
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHH
RMCLVVGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQLVRAQLMALQAQIEPH
HHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLFNSLANLDGLIATDPRAARKLLQRLIGFLRTSLSHTRAEQCTLRQEFELLRSYLDIQG
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MRFGTRLGYDFDLPAELAGVEIPPMLIQPLVENAVTHGIEPCMRGGHITLSARAAGEDAV
CEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCEE
QVIIADTGVGFGHGSGKGSGLGLTHVRERLARIFGAAASMQMEENTPRGVVVRLTLPMTR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEECCCCCCCEEEEEEECCCC
HTEVPMPAPAAPPVPATPAGATPAMPRLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAMERCISAAIPSRLTILGRDLLFVLCMNTVIAVSLNYGFQTGGTLWHNFVYSHLIGIS
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
IWMLIDIPRVMIWWNDRPRRWPFLFLAAAAVPMGVVLGSWATREVLNLPPKLSAETGDML
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHH
RMCLVVGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQLVRAQLMALQAQIEPH
HHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLFNSLANLDGLIATDPRAARKLLQRLIGFLRTSLSHTRAEQCTLRQEFELLRSYLDIQG
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MRFGTRLGYDFDLPAELAGVEIPPMLIQPLVENAVTHGIEPCMRGGHITLSARAAGEDAV
CEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCEE
QVIIADTGVGFGHGSGKGSGLGLTHVRERLARIFGAAASMQMEENTPRGVVVRLTLPMTR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEECCCCCCCEEEEEEECCCC
HTEVPMPAPAAPPVPATPAGATPAMPRLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]