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The map label for this gene is gsiC [H]

Identifier: 73541614

GI number: 73541614

Start: 2110723

End: 2111643

Strand: Reverse

Name: gsiC [H]

Synonym: Reut_A1925

Alternate gene names: 73541614

Gene position: 2111643-2110723 (Counterclockwise)

Preceding gene: 73541615

Following gene: 73541613

Centisome position: 55.47

GC content: 64.39

Gene sequence:

>921_bases
ATGCTGAACTATTTCCTCAAACGATGCCTGGGCGTGATCCCGACACTGCTGATCGTGGCAGTGCTGGTATTCCTGTTCGT
CCACCTCCTGCCCGGCGATCCGGCGCGGTTGGCGGCGGGCCCCGAGGCCGACGAAGCCACCGTCGAGCTGGTGCGCAAGG
ACCTGGGGCTGGACAAAACCCTGCCCGAGCAGTTCGTGAACTTCTTCTCGAACGCCGTGCGCGGCGAGTTCGGGCATTCG
CTGCGCACCAAGCGTGCGGTCAGCGATGAGATCGGCGACCGCTTCATGCCGACGCTGTGGCTGACCGTGGCGTCGATGGC
CTGGGCCGTCGTGTTCGGCATGGTGATCGGCATCTGCTCCGCGGTCTGGCGCAACCGCTGGCCAGACCGGCTCGGCATGA
CGCTGGCCGTGTCCGGCATCTCGTTCCCGGCGTTTGCGCTCGGCATGCTGCTGATGGAAGTGTTCTCGGTGCAGCTCGGC
TGGCTGCCGTCGATCGGCGCCGATAGCTGGAAGCACTACGTGCTGCCGTCGCTGACGCTGGGCGCAGCCGTGGCAGCGGT
GATGGCGCGTTTTACGCGTGCGTCGTTTGTCGAGGTGCTGCAGGAAGATTTCGTGCGTACTGCGCGCGCCAAGGGCGTGC
GCGAGACCGTGGTCGTGGCCAAGCACACGCTGCGCAACGCGATGATTCCCGTGGTGACCATGATGGGCCTGCAGTTCGGC
TTCCTGCTGGGCGGCTCGATCGTGGTGGAGAAAGTCTTCAACTGGCCGGGCCTCGGGCGCCTGCTGGTCGATGCCGTCGA
GATGCGCGACTACCCGGTGATCCAGGCCGAGGTGCTGCTGTTCTCGCTTGAATTCATCCTGATCAACCTGGTGGTGGACT
TGCTCTACACCGTGATCAACCCAACCATCCGCTACAAGTAA

Upstream 100 bases:

>100_bases
CCGCGGCGCGCACCGGGTAGCAAGCAGTAAGCCGAACGTGGCCGCCTGTCCCATCGCAGGGGCATGGACAGGCGGCCTGC
GGCCTTTTCCCTGAAGCGTC

Downstream 100 bases:

>100_bases
AAGGAGGCAGGCATGACCGAGATTTCCACGCCCGCCGACACCCCGGCAGCCACCGTCGCAGCGGCCCCTCAGGCCGTGCG
GACGCCCTGGACCGAGTTCT

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLNYFLKRCLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEATVELVRKDLGLDKTLPEQFVNFFSNAVRGEFGHS
LRTKRAVSDEIGDRFMPTLWLTVASMAWAVVFGMVIGICSAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYVLPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHTLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDLLYTVINPTIRYK

Sequences:

>Translated_306_residues
MLNYFLKRCLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEATVELVRKDLGLDKTLPEQFVNFFSNAVRGEFGHS
LRTKRAVSDEIGDRFMPTLWLTVASMAWAVVFGMVIGICSAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYVLPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHTLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDLLYTVINPTIRYK
>Mature_306_residues
MLNYFLKRCLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEATVELVRKDLGLDKTLPEQFVNFFSNAVRGEFGHS
LRTKRAVSDEIGDRFMPTLWLTVASMAWAVVFGMVIGICSAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYVLPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHTLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDLLYTVINPTIRYK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=79.0849673202614, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=40.4129793510324, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=37.6623376623377, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=38.9570552147239, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787497, Length=310, Percent_Identity=35.1612903225806, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI1787550, Length=278, Percent_Identity=29.136690647482, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=26.9972451790634, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33917; Mature: 33917

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYFLKRCLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEATVELVRKDLGLDKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCC
LPEQFVNFFSNAVRGEFGHSLRTKRAVSDEIGDRFMPTLWLTVASMAWAVVFGMVIGICS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWRNRWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLGWLPSIGADSWKHYVLPSLTL
HHHHCCCCHHHCHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHH
GAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHTLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDLLYTVIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYK
CCCCCC
>Mature Secondary Structure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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA