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The map label for this gene is frr [H]

Identifier: 73541567

GI number: 73541567

Start: 2055078

End: 2055638

Strand: Reverse

Name: frr [H]

Synonym: Reut_A1878

Alternate gene names: 73541567

Gene position: 2055638-2055078 (Counterclockwise)

Preceding gene: 73541568

Following gene: 73541566

Centisome position: 54.0

GC content: 61.85

Gene sequence:

>561_bases
ATGAGCGTCGCCGAAACCAAGAAGAGCGTCGAGCAGAAGATGCAGAAGTCGATCGAGGCCTTCAAGGCCGATCTGGCTAA
AGTCCGCACCGGCCGTGCCCACGTCGGCCTGCTCGACCACGTACAGGTGGACTACTACGGTTCGATGGTGCCGATCAGCC
AGGTGGCCAATATCGGCCTTGGCGATGCCCGCACCATTACCGTGCAGCCGTGGGAAAAGAAGATGGTCGGCGCGGTCGAG
AAGGCAATCCGCGACTGCGACCTCGGCCTGAACCCGGCGACGATGGGCGAAGTTATCCGCGTGCCGATGCCGCCGCTGAC
GGAAGAGCGCCGCAAGGAGCTGACCAAGGTTGTCAAGGGCGAAGCCGAAGGCGCCAAGATCGCTGTGCGCAACCTGCGCC
GCGACGCCAACGAGCAGTTCAAGAAGCTGGTCAAGGACAAGGCGATCTCCGAGGACGACGAGCGCCGCGGCCAGGACGAC
GTGCAGAAGCTGACCGACAAGTATGTGGCGGAAATCGACAAGATGGTCGCCGAGAAAGAGAAGGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
GCCGGCCGCGGAATCTGTTGCGCGGGCCGGCAAAGAGTAGAATGATTCATTTTCGATCCCGGTATTTCGGGATCCTGGTA
GCTGATTTCCGGAGGTAATC

Downstream 100 bases:

>100_bases
CGGTTTCCCGGCGCTCTGCCGCCGGGACCTTCAGTGTCGTCTGCCATCATGCAGCACATCAGTTCTACGCTCGCCGTCCC
CGACAGTACCTATGTGCCCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGLGDARTITVQPWEKKMVGAVE
KAIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKGEAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDD
VQKLTDKYVAEIDKMVAEKEKEIMTV

Sequences:

>Translated_186_residues
MSVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGLGDARTITVQPWEKKMVGAVE
KAIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKGEAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDD
VQKLTDKYVAEIDKMVAEKEKEIMTV
>Mature_185_residues
SVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGLGDARTITVQPWEKKMVGAVEK
AIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKGEAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDDV
QKLTDKYVAEIDKMVAEKEKEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32.6666666666667, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=54.3956043956044, Blast_Score=211, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24661488, Length=181, Percent_Identity=29.2817679558011, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20835; Mature: 20704

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
GDARTITVQPWEKKMVGAVEKAIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKG
CCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
EAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDDVQKLTDKYVAEIDKMVAEKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KEIMTV
HHHCCC
>Mature Secondary Structure 
SVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
GDARTITVQPWEKKMVGAVEKAIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKG
CCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
EAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDDVQKLTDKYVAEIDKMVAEKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KEIMTV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA