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The map label for this gene is lpxA [H]

Identifier: 73541558

GI number: 73541558

Start: 2045178

End: 2045981

Strand: Reverse

Name: lpxA [H]

Synonym: Reut_A1869

Alternate gene names: 73541558

Gene position: 2045981-2045178 (Counterclockwise)

Preceding gene: 73541559

Following gene: 73541557

Centisome position: 53.75

GC content: 64.8

Gene sequence:

>804_bases
ATGACGCAAATCCATCCCACCGCACTGGTCGATCCGAAAGCAGAACTTGCGGCTGACGTGACCGTCGGCCCGTTTTCCAT
TGTCGGCCCGAACGTGCGGATCGGCAGCGGCACGAGTATCGGCGCACATTCCACGGTGGAAGGACACACCACCATCGGCC
AGGGCAACAACATCGGCCCTTACGCTTCCGTGGGTGGCGTGCCGCAGGACATGAAGTACCGTAACGAGCCGACGCGGCTC
GACATCGGCGATCGCAATACCATCCGCGAGTTCACCACGATCCATACGGGAACGGTGCAGGATCGTGGCGTGACCACGAT
CGGCAGCGACAACTGGATCATGGCGTACGTGCACATCGCGCACGACTGCACGGTGGGCAACCACACGGTGTTCTCGAGCA
ATGCGCAGATCGCCGGCCACGTGGAAGTGGGCGACTGGGCCATCCTCGGCGGCATGAGCGGCGTGCACCAGTTCGTGCGC
ATCGGCGCGCATGCGATGCTGGGCGGTGCGTCGGCCCTGGTGCAGGACGTGCCCCCGTTCGTGATCGCCGCGAGCGACAA
GAACGGCAACAAGGCCACACCGCACGGCATCAACGTCGAAGGCTTGCGTCGCCGTGGCTTCGACGCGGGTCAGATTGCCG
GCCTGCGCCAAGCCTACAAGCTGCTGTACAAGTCGGATCTCAGTTTCGACGAGGCGCGCAACGAGATCGCTGCGCTGCTG
GCCCAGGCCGATGCAAGCGCGGCAGAACCGCTGCGCGCGTTCCTCGACTTCATCGCCGCCACCCAGCGCGGCATCGTGCG
CTGA

Upstream 100 bases:

>100_bases
AGGCGGCGGTAGGCCCTGAAAGGCCACCACATGCCGCCATTCCTGGGCCGGGCGGCCCAGCCCCCAGGCCCCCAGACACC
AGACCAACAGGACAGGACGT

Downstream 100 bases:

>100_bases
GACTGGCCCGGACATGGTCGACGCTGCGATTCGGGGCACATTGCCTGCCGGTACCGGGACCAACGCCAGCCAGCGTGGCA
CGATTGCCATGGTCGCCGGC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGPYASVGGVPQDMKYRNEPTRL
DIGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIAHDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVR
IGAHAMLGGASALVQDVPPFVIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALL
AQADASAAEPLRAFLDFIAATQRGIVR

Sequences:

>Translated_267_residues
MTQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGPYASVGGVPQDMKYRNEPTRL
DIGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIAHDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVR
IGAHAMLGGASALVQDVPPFVIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALL
AQADASAAEPLRAFLDFIAATQRGIVR
>Mature_266_residues
TQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGPYASVGGVPQDMKYRNEPTRLD
IGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIAHDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVRI
GAHAMLGGASALVQDVPPFVIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALLA
QADASAAEPLRAFLDFIAATQRGIVR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=264, Percent_Identity=53.7878787878788, Blast_Score=291, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28199; Mature: 28068

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGP
CCCCCCCEEECCHHHHEECCEECCEEEECCCEEECCCCCCCCCCCCCCCEEECCCCCCCC
YASVGGVPQDMKYRNEPTRLDIGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIA
CHHCCCCCCHHHCCCCCCEEECCCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEEEEEE
HDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVRIGAHAMLGGASALVQDVPPF
EECCCCCCEEEECCCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
VIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALL
EEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQADASAAEPLRAFLDFIAATQRGIVR
HHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQIHPTALVDPKAELAADVTVGPFSIVGPNVRIGSGTSIGAHSTVEGHTTIGQGNNIGP
CCCCCCEEECCHHHHEECCEECCEEEECCCEEECCCCCCCCCCCCCCCEEECCCCCCCC
YASVGGVPQDMKYRNEPTRLDIGDRNTIREFTTIHTGTVQDRGVTTIGSDNWIMAYVHIA
CHHCCCCCCHHHCCCCCCEEECCCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEEEEEE
HDCTVGNHTVFSSNAQIAGHVEVGDWAILGGMSGVHQFVRIGAHAMLGGASALVQDVPPF
EECCCCCCEEEECCCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
VIAASDKNGNKATPHGINVEGLRRRGFDAGQIAGLRQAYKLLYKSDLSFDEARNEIAALL
EEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQADASAAEPLRAFLDFIAATQRGIVR
HHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA