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The map label for this gene is fabZ

Identifier: 73541559

GI number: 73541559

Start: 2046110

End: 2046562

Strand: Reverse

Name: fabZ

Synonym: Reut_A1870

Alternate gene names: 73541559

Gene position: 2046562-2046110 (Counterclockwise)

Preceding gene: 73541560

Following gene: 73541558

Centisome position: 53.76

GC content: 60.04

Gene sequence:

>453_bases
ATGACCGCCGCCGAGATCGACATCCGCCAGATTCTGAAACTGCTGCCGCATCGCTATCCGATGCTGCTGGTGGACCGTGT
GCTCGAATTCGAACCGCAGAAGCGAATCAAGACGCTGAAGAACGTCACGATCAACGAGCCGTTCTTCCAGGGACATTTTC
CCGGCCAGCCGGTGATGCCTGGCGTGATGATCCTGGAAGCGCTGGCCCAGTCCGCCGGTCTGCTGACCTTCGGCGCCGAC
ATGGAGCGCAAGGAAGGCGCGCTGTATTACTTCGTCGGCATCGACGGCGCGCGCTTCAAGCAGGTCGTCTATCCGGGGGA
CCAACTGCACATGAACGTGACCGTGGAGCGCTATATCCGCGGCATCTGGAAGTTCAAGGCGTTTGCCACAGTGGACGAGA
AGGTCGCGTGTGAAGCGGAACTGATGTGCACTGTCAAGCAGGCTGACGCCTGA

Upstream 100 bases:

>100_bases
CGTGGCCTGACCAAGCTGCGTGAACGCGTCATGCAACTGGAGCGCCGCCTGCGCGGCCAGTCCGCCGGGACCCAAACCTC
ACAAGACTAAGAGAAACATC

Downstream 100 bases:

>100_bases
GTCCCGCGCCCGCGGCGCGCCGCGGGCAAGGCGGCGGTAGGCCCTGAAAGGCCACCACATGCCGCCATTCCTGGGCCGGG
CGGCCCAGCCCCCAGGCCCC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTAAEIDIRQILKLLPHRYPMLLVDRVLEFEPQKRIKTLKNVTINEPFFQGHFPGQPVMPGVMILEALAQSAGLLTFGAD
MERKEGALYYFVGIDGARFKQVVYPGDQLHMNVTVERYIRGIWKFKAFATVDEKVACEAELMCTVKQADA

Sequences:

>Translated_150_residues
MTAAEIDIRQILKLLPHRYPMLLVDRVLEFEPQKRIKTLKNVTINEPFFQGHFPGQPVMPGVMILEALAQSAGLLTFGAD
MERKEGALYYFVGIDGARFKQVVYPGDQLHMNVTVERYIRGIWKFKAFATVDEKVACEAELMCTVKQADA
>Mature_149_residues
TAAEIDIRQILKLLPHRYPMLLVDRVLEFEPQKRIKTLKNVTINEPFFQGHFPGQPVMPGVMILEALAQSAGLLTFGADM
ERKEGALYYFVGIDGARFKQVVYPGDQLHMNVTVERYIRGIWKFKAFATVDEKVACEAELMCTVKQADA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=57.9710144927536, Blast_Score=175, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CUPPJ (Q470E8)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_296079.1
- ProteinModelPortal:   Q470E8
- SMR:   Q470E8
- GeneID:   3609257
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A1870
- NMPDR:   fig|264198.3.peg.2400
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   REUT264198:REUT_A1870-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17034; Mature: 16903

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: ACT_SITE 52-52

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAEIDIRQILKLLPHRYPMLLVDRVLEFEPQKRIKTLKNVTINEPFFQGHFPGQPVMP
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GVMILEALAQSAGLLTFGADMERKEGALYYFVGIDGARFKQVVYPGDQLHMNVTVERYIR
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHEEECCCCEEEEEEEHHHHHH
GIWKFKAFATVDEKVACEAELMCTVKQADA
HHHHHHHHHCCCHHHHCCHHHEEEEECCCC
>Mature Secondary Structure 
TAAEIDIRQILKLLPHRYPMLLVDRVLEFEPQKRIKTLKNVTINEPFFQGHFPGQPVMP
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GVMILEALAQSAGLLTFGADMERKEGALYYFVGIDGARFKQVVYPGDQLHMNVTVERYIR
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHEEECCCCEEEEEEEHHHHHH
GIWKFKAFATVDEKVACEAELMCTVKQADA
HHHHHHHHHCCCHHHHCCHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA