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The map label for this gene is yngJ [H]

Identifier: 73541524

GI number: 73541524

Start: 2009589

End: 2010773

Strand: Reverse

Name: yngJ [H]

Synonym: Reut_A1835

Alternate gene names: 73541524

Gene position: 2010773-2009589 (Counterclockwise)

Preceding gene: 73541525

Following gene: 73541523

Centisome position: 52.82

GC content: 64.56

Gene sequence:

>1185_bases
ATGCAGGCCGGCGCAACCCAACAACGGAGAGACGAAGTGCAACCGAACTTCCTGAATGAATCCCAGGCCCTGTGGCTCGA
CACCGTGAACCGCTTCATGGACAACGAGGTCACGGTCGAATACGTACGCAAGTGCGACCAGAACCGCGACTATCCGTACG
AGGCCTACGACAAGATCGCGAAGCAGGGCTGGCTGGGCCTGCTGTTCAGCGAGGAAGAGGGCGGCGCGGGCGGCGACATC
TTCGACTACACGCTCATGGCCGAGGGCCTCGGCAAGTTTGGCTTCGACTTCGCGGCCGCGGTGCTGGTACCGACCTTCAC
CGCGATGAATATCGGTAAGTACGGCACGGCTGCGCAGAAGGACAAGTACATCAAGCCGTTTATCGACGGCAAGATCCGCT
TCTCGGTGTCGATCTCCGAGCCCGACGCCGGCTCCGACGCCTCGAACACCAAGACCCGCGCGCGCCGCGACGAGAACGGC
GACTGGATCGTCTCGGGCCAGAAGCTGTGGTGCAGCGGCGCGGCGGCGAAGGACACGGTCATTGCCATGCTGGTGCGCAC
CGATGCCGACAACAAGCACGGTGGCCTCTCCGTGCTGCTGATTCCCAACTCCACGCCGGGGCTGGTCATCAACAAGCTGC
CGACGCTGTCGCGCCACGCCACGGGCACCACCGAGATTTTCCTCGATGAAGTCCGCGTGCCGGCCGACGCCCTGCTGGGC
GAGGAAGGCCAGGGCTGGGAAATCATTACCAAGCACCTTGAACTGGAGCGCTGCGCGGTGGCCGCTGCCTATGTCGGCAA
CGCGCAGACGGCAGTGTCGAAGGCCACGCAGTACGCCCACGAGCGCATCCAGTTCGGCAAGCAGTTGTGGGACTTCCAGG
TGCTCAAGCACATGCTGGCGGACCGCCAGACCGAAGTGGATGCCGCGCGCCTGCTGTGCTACCGCGCTGCGCAGATGGCG
GCGGCCGACGTGCCGTGCAGCCGCGAAGTGTCGATGGCGAAGCTGTACGGCTCCGAAACGCTCAAGCAGTGCGCGCTGAC
CGGCATGCAAGTGCTCGGCGGCTACGCCAACCTGCCCGAAGCCGACATGGAGCGCTACCTGCGCGAAAGCGTGCAGTCCA
CCATCGGCGGCGGCACCTCGCAGATCCAGAAGACCATCATCGCCAAGTCGATGCGGATCGGCTGA

Upstream 100 bases:

>100_bases
GCCCGCCTTTTTCATTTCGCCCGCACCGAAACGCCGCTTCAAAAATGGCCAGTTGGCCTCGCGGTGGCACGACTCTACTC
TTCCAATACGCGCCGCATAC

Downstream 100 bases:

>100_bases
ACCAGACGACATAGAAGGAGAAAGACATGAGCGACACGAGCAAGCGCATCATCAACAACCGCATCGACCAGACCTATGAC
GAACTGGAGATCGGCCAGGT

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQAGATQQRRDEVQPNFLNESQALWLDTVNRFMDNEVTVEYVRKCDQNRDYPYEAYDKIAKQGWLGLLFSEEEGGAGGDI
FDYTLMAEGLGKFGFDFAAAVLVPTFTAMNIGKYGTAAQKDKYIKPFIDGKIRFSVSISEPDAGSDASNTKTRARRDENG
DWIVSGQKLWCSGAAAKDTVIAMLVRTDADNKHGGLSVLLIPNSTPGLVINKLPTLSRHATGTTEIFLDEVRVPADALLG
EEGQGWEIITKHLELERCAVAAAYVGNAQTAVSKATQYAHERIQFGKQLWDFQVLKHMLADRQTEVDAARLLCYRAAQMA
AADVPCSREVSMAKLYGSETLKQCALTGMQVLGGYANLPEADMERYLRESVQSTIGGGTSQIQKTIIAKSMRIG

Sequences:

>Translated_394_residues
MQAGATQQRRDEVQPNFLNESQALWLDTVNRFMDNEVTVEYVRKCDQNRDYPYEAYDKIAKQGWLGLLFSEEEGGAGGDI
FDYTLMAEGLGKFGFDFAAAVLVPTFTAMNIGKYGTAAQKDKYIKPFIDGKIRFSVSISEPDAGSDASNTKTRARRDENG
DWIVSGQKLWCSGAAAKDTVIAMLVRTDADNKHGGLSVLLIPNSTPGLVINKLPTLSRHATGTTEIFLDEVRVPADALLG
EEGQGWEIITKHLELERCAVAAAYVGNAQTAVSKATQYAHERIQFGKQLWDFQVLKHMLADRQTEVDAARLLCYRAAQMA
AADVPCSREVSMAKLYGSETLKQCALTGMQVLGGYANLPEADMERYLRESVQSTIGGGTSQIQKTIIAKSMRIG
>Mature_394_residues
MQAGATQQRRDEVQPNFLNESQALWLDTVNRFMDNEVTVEYVRKCDQNRDYPYEAYDKIAKQGWLGLLFSEEEGGAGGDI
FDYTLMAEGLGKFGFDFAAAVLVPTFTAMNIGKYGTAAQKDKYIKPFIDGKIRFSVSISEPDAGSDASNTKTRARRDENG
DWIVSGQKLWCSGAAAKDTVIAMLVRTDADNKHGGLSVLLIPNSTPGLVINKLPTLSRHATGTTEIFLDEVRVPADALLG
EEGQGWEIITKHLELERCAVAAAYVGNAQTAVSKATQYAHERIQFGKQLWDFQVLKHMLADRQTEVDAARLLCYRAAQMA
AADVPCSREVSMAKLYGSETLKQCALTGMQVLGGYANLPEADMERYLRESVQSTIGGGTSQIQKTIIAKSMRIG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=31.4666666666667, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=33.2432432432432, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=28.2666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226958412, Length=403, Percent_Identity=26.302729528536, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=27.2463768115942, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI187960098, Length=390, Percent_Identity=28.974358974359, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4557231, Length=390, Percent_Identity=28.974358974359, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=27.1052631578947, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI21361497, Length=389, Percent_Identity=28.5347043701799, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=29.96632996633, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=26.1538461538462, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=26.1538461538462, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI211971008, Length=333, Percent_Identity=25.2252252252252, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI48976061, Length=333, Percent_Identity=25.2252252252252, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4503943, Length=339, Percent_Identity=25.3687315634218, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7669494, Length=282, Percent_Identity=26.9503546099291, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87081958, Length=367, Percent_Identity=29.4277929155313, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=25.7217847769029, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082384, Length=306, Percent_Identity=24.5098039215686, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=33.9522546419098, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=32.9842931937173, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=27.8215223097113, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=28.8359788359788, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=28.9256198347107, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=392, Percent_Identity=27.5510204081633, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=34.0425531914894, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=353, Percent_Identity=29.1784702549575, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17551932, Length=344, Percent_Identity=27.906976744186, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=349, Percent_Identity=26.647564469914, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985184, Length=391, Percent_Identity=26.0869565217391, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=33.7606837606838, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=318, Percent_Identity=26.7295597484277, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=27.9761904761905, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=293, Percent_Identity=27.9863481228669, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=348, Percent_Identity=25.5747126436782, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=31.4814814814815, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=30.7894736842105, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=29.6296296296296, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=30.3370786516854, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24660351, Length=401, Percent_Identity=29.1770573566085, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281363737, Length=283, Percent_Identity=27.9151943462898, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19920834, Length=332, Percent_Identity=27.710843373494, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43277; Mature: 43277

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAGATQQRRDEVQPNFLNESQALWLDTVNRFMDNEVTVEYVRKCDQNRDYPYEAYDKIA
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
KQGWLGLLFSEEEGGAGGDIFDYTLMAEGLGKFGFDFAAAVLVPTFTAMNIGKYGTAAQK
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DKYIKPFIDGKIRFSVSISEPDAGSDASNTKTRARRDENGDWIVSGQKLWCSGAAAKDTV
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEECCEEEECCCCHHHHH
IAMLVRTDADNKHGGLSVLLIPNSTPGLVINKLPTLSRHATGTTEIFLDEVRVPADALLG
EEEEEECCCCCCCCCEEEEEECCCCCCEEEECCCCCHHCCCCCHHHHHHHHCCCHHHHCC
EEGQGWEIITKHLELERCAVAAAYVGNAQTAVSKATQYAHERIQFGKQLWDFQVLKHMLA
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRQTEVDAARLLCYRAAQMAAADVPCSREVSMAKLYGSETLKQCALTGMQVLGGYANLPE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ADMERYLRESVQSTIGGGTSQIQKTIIAKSMRIG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAGATQQRRDEVQPNFLNESQALWLDTVNRFMDNEVTVEYVRKCDQNRDYPYEAYDKIA
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
KQGWLGLLFSEEEGGAGGDIFDYTLMAEGLGKFGFDFAAAVLVPTFTAMNIGKYGTAAQK
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DKYIKPFIDGKIRFSVSISEPDAGSDASNTKTRARRDENGDWIVSGQKLWCSGAAAKDTV
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEECCEEEECCCCHHHHH
IAMLVRTDADNKHGGLSVLLIPNSTPGLVINKLPTLSRHATGTTEIFLDEVRVPADALLG
EEEEEECCCCCCCCCEEEEEECCCCCCEEEECCCCCHHCCCCCHHHHHHHHCCCHHHHCC
EEGQGWEIITKHLELERCAVAAAYVGNAQTAVSKATQYAHERIQFGKQLWDFQVLKHMLA
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRQTEVDAARLLCYRAAQMAAADVPCSREVSMAKLYGSETLKQCALTGMQVLGGYANLPE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ADMERYLRESVQSTIGGGTSQIQKTIIAKSMRIG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]