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The map label for this gene is stc [H]

Identifier: 73541496

GI number: 73541496

Start: 1973633

End: 1975624

Strand: Reverse

Name: stc [H]

Synonym: Reut_A1807

Alternate gene names: 73541496

Gene position: 1975624-1973633 (Counterclockwise)

Preceding gene: 73541503

Following gene: 73541491

Centisome position: 51.9

GC content: 67.82

Gene sequence:

>1992_bases
ATGCCACCGACCGTTTCTTCCCCCGGCCTGCCACGCATCTGGGCGCTCGGCATCAGCCGTCTGCAGCGCGCTTTCGCCGA
ACTGATTCCCGCCTATTCCCACCTTGCAGAGTTCCGCATCGTCGGGCGCGCCTATGACTCCGCGGCCGACGCGATCCGCC
GCGAGGCGCGCGAGGGCAAGCTCGATGTCGTCGTGTCCGGCGGCTCGAATGGCGCCTACCTGCGCCAGCACGTGGATGTG
CCGGTGGTGCTGGTCAAGGTTACGGGCTTCGATGTGATGAGCGCGCTCGCGACAGCGCGGCGCATCTCGCCAAATGTGGC
GCTGGTGACGCATGCGTCCACCTATGCCGAAGTGGATGAATTCACGCGCGCGTTCTCGCTGTCGATTCCGGCCTACACCT
ATCTGACCGAAGACGATGCGACCGCCCGCGTGCAGACGCTAAAGCAGGAGGGCGTAAAGGTGGTGGTCGGCCCCGGTCTG
GTGACGGACCTGGCGGACCGCCTCGGCCTGATCGGCGTCTTTCTCTATTCCGGCAACTCCGTGCGCATGGCGCTCGAGGA
CGCGATCGAAGCGGCCCGGCTGCGGCGCATCGAGTCCGGCCGGCGCGACTACGTCAACAACATCCTCGCGCACCTGAACG
AGGGCGTGGCGGCCGTCGACGGTGAGGGGCGCATCCAGTCGTTCAACCCGGCGATGGAACGCTTTCTCGGCACGCCTGCC
GCGAGCGCCGTCGGGCGCAAGCTGCAGTCGCTGTCGCCGGGGCTGTCGCTGGACGATGTAATCCAGACTGGCGCCAAGGA
ACTCGAAGCGATCCAGAAGGTGGGCGACCGCATGGTGGTGGTCAACCGCATCCCGCTCGCGAATGAATCCGGCACTACGG
GCGCGCTGCTGACGCTGCAGGACGCGACGGCCATCCAGCGCGTGGACCGCAACCTGCGTTCGCGCAGCCGTACGCGCCTG
CCCGGTGTGCGCTACAGCCTGGAGGACCTGGCCGGCACGTCGGCAGCCATGATGCACGTGCGCGAACTTGCGCGGCGCTA
TGCGTCGGTCGACTCCACCGTGCTGATTGGCGGCGAGAGCGGTACTGGCAAAGAGGTGCTGGCACAAGGCATGCACGACG
CGAGCCCGCGCCGCGCGTTCCCGTTCGTGGCGGTCAATTGCGCCGCGTTTCCCGAAACGCTGCTGGAAAGCGAACTGTTC
GGCTACGAGGAGGGCGCCTTCACCGGCGCGCGGCGCGGCGGCAAGGCTGGCCTGTTCGAGTCTGCCCACAACGGCACGCT
CTTCCTCGATGAAGTCGGCGACATGCCGCCCGCTCTGCAGACGCGTTTGCTGCGCGTGCTTCAGGAAAAGCAGGTGCTGC
CGATCGGCGGGCTGGAAGCTGTGCCGGTCAATGTGCGCGTGATCGCCGCCACACACAGGGACCTGGTGCAGCGCGTCAGC
GAGGGGACCTTCCGGCAGGATCTTTACTACCGGCTGAATATCCTGCGCATCGAAGTGCCGCCGCTGCGCGCGCGCGCGGA
GGACCTGCCTGAGCTGGCCGAACTGCTTTACCGGCGCGCGCTCGAACGGCTGGGCCTTGAGGATCACGAAGGCTTGCCGC
AAGCGGCCCGCGCCCGCCTGGCGGGCTATCACTGGCCGGGCAATATCCGCGAACTGGAAAACGTGACGGAGCGCATCGCC
GTGCTGGTCGCCGGCCGGCCGCTGGAACCGGCGGAATTGCTGCGCGAACTGCAGGCCGCGGTCCCGGAATTGTTTGGCGA
TGATCTGGGCGCCATGCCTGATGCCGCGATCTCCGTGGATGAGCCCGTACAGGAACCTATGCGCGGTGGCCGCCAGCGTC
GCGTCGGCCGTTCGCTAGCCGGTGTTGCGCAGGCCAGCGAAGCCGAGCATATCCGCCGCGTGCTGGCCGAGTGCGGTGGC
GACCGCAACGCGGCGTGCCACATCCTCGGGATCAGCCCGACCACGCTGTGGCGCCGGCTCCGGGCTGCCTGA

Upstream 100 bases:

>100_bases
TTTCATCCCTGCCTTGCATTTCATTGGCGCAATTCGCATTGCATGATTGAAATTCAAGCGGCTGACGCGCACAATAGCGG
CACTCTACGCCTTAAACACC

Downstream 100 bases:

>100_bases
GCGGCTGTATCAGGCCGGCGTCTTGCGGAACGAAATCGCGAAGCGGTTCCAGGTGTTGATGGCGGCCACCAGCAACGTAA
GGTTGACCAGTTCCGCATCG

Product: PAS:helix-turn-helix, Fis-type:propionate catabolism activator, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MPPTVSSPGLPRIWALGISRLQRAFAELIPAYSHLAEFRIVGRAYDSAADAIRREAREGKLDVVVSGGSNGAYLRQHVDV
PVVLVKVTGFDVMSALATARRISPNVALVTHASTYAEVDEFTRAFSLSIPAYTYLTEDDATARVQTLKQEGVKVVVGPGL
VTDLADRLGLIGVFLYSGNSVRMALEDAIEAARLRRIESGRRDYVNNILAHLNEGVAAVDGEGRIQSFNPAMERFLGTPA
ASAVGRKLQSLSPGLSLDDVIQTGAKELEAIQKVGDRMVVVNRIPLANESGTTGALLTLQDATAIQRVDRNLRSRSRTRL
PGVRYSLEDLAGTSAAMMHVRELARRYASVDSTVLIGGESGTGKEVLAQGMHDASPRRAFPFVAVNCAAFPETLLESELF
GYEEGAFTGARRGGKAGLFESAHNGTLFLDEVGDMPPALQTRLLRVLQEKQVLPIGGLEAVPVNVRVIAATHRDLVQRVS
EGTFRQDLYYRLNILRIEVPPLRARAEDLPELAELLYRRALERLGLEDHEGLPQAARARLAGYHWPGNIRELENVTERIA
VLVAGRPLEPAELLRELQAAVPELFGDDLGAMPDAAISVDEPVQEPMRGGRQRRVGRSLAGVAQASEAEHIRRVLAECGG
DRNAACHILGISPTTLWRRLRAA

Sequences:

>Translated_663_residues
MPPTVSSPGLPRIWALGISRLQRAFAELIPAYSHLAEFRIVGRAYDSAADAIRREAREGKLDVVVSGGSNGAYLRQHVDV
PVVLVKVTGFDVMSALATARRISPNVALVTHASTYAEVDEFTRAFSLSIPAYTYLTEDDATARVQTLKQEGVKVVVGPGL
VTDLADRLGLIGVFLYSGNSVRMALEDAIEAARLRRIESGRRDYVNNILAHLNEGVAAVDGEGRIQSFNPAMERFLGTPA
ASAVGRKLQSLSPGLSLDDVIQTGAKELEAIQKVGDRMVVVNRIPLANESGTTGALLTLQDATAIQRVDRNLRSRSRTRL
PGVRYSLEDLAGTSAAMMHVRELARRYASVDSTVLIGGESGTGKEVLAQGMHDASPRRAFPFVAVNCAAFPETLLESELF
GYEEGAFTGARRGGKAGLFESAHNGTLFLDEVGDMPPALQTRLLRVLQEKQVLPIGGLEAVPVNVRVIAATHRDLVQRVS
EGTFRQDLYYRLNILRIEVPPLRARAEDLPELAELLYRRALERLGLEDHEGLPQAARARLAGYHWPGNIRELENVTERIA
VLVAGRPLEPAELLRELQAAVPELFGDDLGAMPDAAISVDEPVQEPMRGGRQRRVGRSLAGVAQASEAEHIRRVLAECGG
DRNAACHILGISPTTLWRRLRAA
>Mature_662_residues
PPTVSSPGLPRIWALGISRLQRAFAELIPAYSHLAEFRIVGRAYDSAADAIRREAREGKLDVVVSGGSNGAYLRQHVDVP
VVLVKVTGFDVMSALATARRISPNVALVTHASTYAEVDEFTRAFSLSIPAYTYLTEDDATARVQTLKQEGVKVVVGPGLV
TDLADRLGLIGVFLYSGNSVRMALEDAIEAARLRRIESGRRDYVNNILAHLNEGVAAVDGEGRIQSFNPAMERFLGTPAA
SAVGRKLQSLSPGLSLDDVIQTGAKELEAIQKVGDRMVVVNRIPLANESGTTGALLTLQDATAIQRVDRNLRSRSRTRLP
GVRYSLEDLAGTSAAMMHVRELARRYASVDSTVLIGGESGTGKEVLAQGMHDASPRRAFPFVAVNCAAFPETLLESELFG
YEEGAFTGARRGGKAGLFESAHNGTLFLDEVGDMPPALQTRLLRVLQEKQVLPIGGLEAVPVNVRVIAATHRDLVQRVSE
GTFRQDLYYRLNILRIEVPPLRARAEDLPELAELLYRRALERLGLEDHEGLPQAARARLAGYHWPGNIRELENVTERIAV
LVAGRPLEPAELLRELQAAVPELFGDDLGAMPDAAISVDEPVQEPMRGGRQRRVGRSLAGVAQASEAEHIRRVLAECGGD
RNAACHILGISPTTLWRRLRAA

Specific function: Involved In The Transcriptional Regulation Of The Propionate Catabolism Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=398, Percent_Identity=42.964824120603, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1788905, Length=242, Percent_Identity=50.4132231404959, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI1789233, Length=475, Percent_Identity=33.8947368421053, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI87082117, Length=240, Percent_Identity=51.25, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1790299, Length=434, Percent_Identity=37.5576036866359, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1790437, Length=342, Percent_Identity=42.6900584795322, Blast_Score=233, Evalue=4e-62,
Organism=Escherichia coli, GI1788550, Length=372, Percent_Identity=37.9032258064516, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789087, Length=357, Percent_Identity=40.0560224089636, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=348, Percent_Identity=38.5057471264368, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=372, Percent_Identity=32.258064516129, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=45.021645021645, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI87081858, Length=477, Percent_Identity=27.4633123689727, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=223, Percent_Identity=39.4618834080717, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72008; Mature: 71877

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTVSSPGLPRIWALGISRLQRAFAELIPAYSHLAEFRIVGRAYDSAADAIRREAREGK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDVVVSGGSNGAYLRQHVDVPVVLVKVTGFDVMSALATARRISPNVALVTHASTYAEVDE
EEEEEECCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
FTRAFSLSIPAYTYLTEDDATARVQTLKQEGVKVVVGPGLVTDLADRLGLIGVFLYSGNS
HHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHEEEEEECCCE
VRMALEDAIEAARLRRIESGRRDYVNNILAHLNEGVAAVDGEGRIQSFNPAMERFLGTPA
EEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCH
ASAVGRKLQSLSPGLSLDDVIQTGAKELEAIQKVGDRMVVVNRIPLANESGTTGALLTLQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEC
DATAIQRVDRNLRSRSRTRLPGVRYSLEDLAGTSAAMMHVRELARRYASVDSTVLIGGES
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
GTGKEVLAQGMHDASPRRAFPFVAVNCAAFPETLLESELFGYEEGAFTGARRGGKAGLFE
CCCHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SAHNGTLFLDEVGDMPPALQTRLLRVLQEKQVLPIGGLEAVPVNVRVIAATHRDLVQRVS
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCEEEEEEEHHHHHHHHHHH
EGTFRQDLYYRLNILRIEVPPLRARAEDLPELAELLYRRALERLGLEDHEGLPQAARARL
CCCHHHHHHEEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AGYHWPGNIRELENVTERIAVLVAGRPLEPAELLRELQAAVPELFGDDLGAMPDAAISVD
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EPVQEPMRGGRQRRVGRSLAGVAQASEAEHIRRVLAECGGDRNAACHILGISPTTLWRRL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
RAA
HCC
>Mature Secondary Structure 
PPTVSSPGLPRIWALGISRLQRAFAELIPAYSHLAEFRIVGRAYDSAADAIRREAREGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDVVVSGGSNGAYLRQHVDVPVVLVKVTGFDVMSALATARRISPNVALVTHASTYAEVDE
EEEEEECCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
FTRAFSLSIPAYTYLTEDDATARVQTLKQEGVKVVVGPGLVTDLADRLGLIGVFLYSGNS
HHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHEEEEEECCCE
VRMALEDAIEAARLRRIESGRRDYVNNILAHLNEGVAAVDGEGRIQSFNPAMERFLGTPA
EEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCH
ASAVGRKLQSLSPGLSLDDVIQTGAKELEAIQKVGDRMVVVNRIPLANESGTTGALLTLQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEC
DATAIQRVDRNLRSRSRTRLPGVRYSLEDLAGTSAAMMHVRELARRYASVDSTVLIGGES
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
GTGKEVLAQGMHDASPRRAFPFVAVNCAAFPETLLESELFGYEEGAFTGARRGGKAGLFE
CCCHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SAHNGTLFLDEVGDMPPALQTRLLRVLQEKQVLPIGGLEAVPVNVRVIAATHRDLVQRVS
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCEEEEEEEHHHHHHHHHHH
EGTFRQDLYYRLNILRIEVPPLRARAEDLPELAELLYRRALERLGLEDHEGLPQAARARL
CCCHHHHHHEEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AGYHWPGNIRELENVTERIAVLVAGRPLEPAELLRELQAAVPELFGDDLGAMPDAAISVD
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EPVQEPMRGGRQRRVGRSLAGVAQASEAEHIRRVLAECGGDRNAACHILGISPTTLWRRL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHH
RAA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA